OIE Reference Laboratory Reports Activities
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1 OIE Reference Laboratory Report Activitie Activitie in 2016 Thi report ha been ubmitted : :46:17 Name of dieae (or topic) for which you are a deignated OIE Reference Laboratory: Glander Addre of laboratory: Naumburger Str. 96a Jena GERMANY Tel.: Fax: addre: heinrich.neubauer@fli.bund.de Webite: Name (including Title) of Head of Laboratory (Reponible Official): Prof. Dr. Heinrich Neubauer Name (including Title and Poition) of OIE Reference Expert: Prof. Dr. Heinrich Neubauer, Head of Intitute of Bacterial Infection and Zoonoe Which of the following define your laboratory? Check all that apply: Governmental OIE Reference Laboratory Report Activitie,
2 ToR 1: To ue, promote and dieminate diagnotic method validated according to OIE Standard 1. Did your laboratory perform for the pecified dieae/topic for purpoe uch a dieae diagnoi, creening of animal for export, urveillance, etc.? (t for quality control, proficiency teting or taff training) Diagnotic Tet Indicated in OIE Manual (/) Total number of tet performed lat year Indirect Nationally Internationally CFT Immunoblot ELISA Direct Nationally Internationally Iolation 1 0 PCR 1 0 ToR 2: To develop reference material in accordance with OIE requirement, and implement and promote the application of OIE Standard. To tore and ditribute to national laboratorie biological reference product and any other reagent ued in the diagnoi and control of the deignated pathogen or dieae. 2. Did your laboratory produce or upply imported tandard reference reagent officially recognied by the OIE? 3. Did your laboratory upply tandard reference reagent (non OIE-approved) and/or other diagnotic reagent to OIE Member Countrie? 2 OIE Reference Laboratory Report Activitie, 2016
3 Type of reagent available Related diagnotic tet Produced/ provide Amount upplied nationally (ml, mg) Amount upplied internationally (ml, mg). of recipient OIE Member Countrie Region of recipient DNA PCR produced/ provided 0 8 vial 3 Eat B.mallei negative control erum erology produced/ provided 0 7 vial 2 Eat B.mallei poitive control erum erology produced/ provided 5 vial 5 vial vial 4 Eat LPS-Antigen erology produced/ provided 15 vial 14 vial 4 Eat LPS-NC-Strip erology produced/ provided Eat unknown DNA interlaboratory tet 6 1 Eat OIE Reference Laboratory Report Activitie,
4 4. Did your laboratory produce vaccine? Glander - Heinrich Neubauer - germany 5. Did your laboratory upply vaccine to OIE Member Countrie? ToR 3: To develop, tandardie and validate, according to OIE Standard, new procedure for diagnoi and control of the deignated pathogen or dieae 6. Did your laboratory develop new diagnotic method validated according to OIE Standard for the deignated pathogen or dieae? 7. Did your laboratory develop new vaccine according to OIE Standard for the deignated pathogen or dieae? ToR 4: To provide diagnotic teting facilitie, and, where appropriate, cientific and technical advice on dieae control meaure to OIE Member Countrie 8. Did your laboratory carry out diagnotic teting for other OIE Member Countrie? Name of OIE Member Country eeking aitance Date (month). ample received for proviion of diagnotic upport. ample received for proviion of confirmatory diagnoe UNITED KINGDOM 7,10, CZECH REPUBLIC FRANCE CHILE CANADA BELGIUM 10, LATVIA 7,8 2 2 PERU 4, Did your laboratory provide expert advice in technical conultancie on the requet of an OIE Member Country? 4 OIE Reference Laboratory Report Activitie, 2016
5 Name of the OIE Member Country receiving a technical conultancy Purpoe How the advice wa provided JAPAN diagnotic training Training on CFT and immunoblot UKRAINE diagnotic training Training on CFT and immunoblot UNITED STATES OF AMERICA diagnotic training Training on CFT and immunoblot CHILE diagnotic training Training on CFT and immunoblot ToR 5: To carry out and/or coordinate cientific and technical tudie in collaboration with other laboratorie, centre or organiation 10. Did your laboratory participate in international cientific tudie in collaboration with OIE Member Countrie other than the own? Title of the tudy Duration Purpoe of the tudy Partner (Intitution) OIE Member Countrie involved other than your country OIE-Tender-Glander Tender ref.: AD/SR/2015/1885 EU-RL for Equine diee, Ane FRANCE OIE-Tender-Glander Tender ref.: AD/SR/2015/1885 ICAR-National Reearch Centre on Equine, Sira Road, Hiar INDIA OIE-Tender-Glander Tender ref.: AD/SR/2015/1885 National Reference laboratory for Glander, Recife BRAZIL OIE-Tender-Glander Tender ref.: AD/SR/2015/1885 Univeridade Federal Rural de Pernambuco OIE-Tender-Glander Tender ref.: AD/SR/2015/1885 Section of Epidemiology and Public Health, College of Veterinary and Animal Science, Jhang PAKISTAN Tender ref.: AD/SR/2015/1885 Department of Clinical Medicine and Surgery, Univerity of Agriculture, Faialabad PAKISTAN OIE Reference Laboratory Report Activitie,
6 ToR 6: To collect, proce, analye, publih and dieminate epizootiological data relevant to the deignated pathogen or dieae 11. Did your Laboratory collect epizootiological data relevant to international dieae control? 12. Did your laboratory dieminate epizootiological data that had been proceed and analyed? 13. What method of diemination of information i mot often ued by your laboratory? (Indicate in the appropriate box the number by category) a) Article publihed in peer-reviewed journal: 2 Mandy C. Elchner, Praad Thoma, Falk Melzer: Complete Genome Sequence of a Burkholderia mallei Iolate Originating from a Glanderou Hore from the Kingdom of Bahrain.Genome Announcement.2016 Volume 4 Iue 6 e Oberteller S, Neubauer H, Hagen RM, Frickmann H. Comparion of Five Commercial Nucleic Acid Extraction Kit for the PCR-baed Detection of Burkholderia Peudomallei DNA in Formalin-Fixed, Paraffin-Embedded Tiue. Eur J Microbiol Immunol (Bp) Sep 29;6(3): b) International conference: 10 Mandy C. Elchner 1, Karine Laroucau 2, Stepahn Zientara 2, Hariankar Singha 3, Malik Praveen 4, Subodh Kumar 5, Ullrich Wernery 6, Vania Lucia de Ai Santana 7, Roberto Soare Catro 8, Rinaldo Aparecido Mota 8, Roman Koziy 9, Iahtaham Khan 10, Muhammad Saqib 11, Te_otimo Becú 12, Nader Moavari 13, Heinrich Neubauer : OIE-Project-Validation tudy of a wetern blot technique and ELISA for erological diagnoi of glander in equid for the purpoe of certifying freedom from infection in individual animal for trade. or movement110th S16 IEIDC Abtract / Journal of Equine Veterinary Science 39 (2016) S7eS19 Neubauer H Global cenario of glander and Experience of an OIE Reference Laboratory. Training Coure at NRCE, Hiar (India) on Glander. 8th February 2016 Elchner MC Bioafety and Laboratory Bioecurity. Training Coure at NRCE, Hiar (India) on Glander. 8th February 2016 Elchner MC Shipping of Infectiou ubtance IATA regulation. Training Coure at NRCE, Hiar (India) on Glander. 8th February 2016 Elchner MC Glander diagnoi by iolation and identification of cauative agent. Training Coure at NRCE, Hiar (India) on Glander. 8th February 2016 Melzer, F. Complement fixation tet. Training Coure at NRCE, Hiar (India) on Glander. 8th February 2016 Elchner MC Advance in diagnoi of glander. Training Coure at NRCE, Hiar (India) on Glander. 8th February 2016 Neubauer H The Global Situation of Glander and the role of the OIE glander Reference Laboratory in control of the dieae. XVII Annual ABRAVEQ Conference Campo do Jordão Convention Center - Campo do Jordão 04/30/2016 Neubauer H Principle of Control and Eradication of Glander. XVII Annual ABRAVEQ Conference Campo do Jordão Convention Center - Campo do Jordão 04/30/2016 Neubauer H When i a cae a cae? Diagnotic of glander. XVII Annual ABRAVEQ Conference Campo do Jordão Convention Center - Campo do Jordão 04/30/2016 c) National conference: 4 Mandy C. Elchner, Jan Hnizdo, Ivonne Stamm, Hony El-Adawy, Katja Merten, Falk Melzer 2016 Firt an cae of a Burkholderia peudomallei infection in a pet green Iguana,3rd Force Health Protection Congre 2016, Tropical Medicine and Infectiou Dieae in an International Military Context, September 2016, Hamburg, Poter. 6 OIE Reference Laboratory Report Activitie, 2016
7 Mandy C. Elchner, Hony El-Adawy, Heinrich Neubauer, Md Abu Sayeed Sarker, Laila Akhter, Md. Siddiqur Rahman 2016 Initial erological invetigation on prevalence of Glander in rural hore of Bangladeh3rd Force Health Protection Congre 2016, Tropical Medicine and Infectiou Dieae in an International Military Context, September 2016, Hamburg, Vortrag Neubauer H Rotz und Brucelloe-re-emerging dieae al globale Bedrohung. Riiken entlang globaler Lebenmittel-Warenketten. BfR, Berlin, Neubauer H Die globale Wiederkehr de equinen Rotze und ihre Auwirkung auf Deutchland. Fortbildung de Landeverbande der beamteten Tierärzte Baden-Württemberg. Dettingen u.t Neubauer H Anzeigepflichtige Tiereuchen und meldepflichtige Tierkrankheiten Fallbeipiele au der Arbeit de Intitut für Bakterielle Infektionen und Zoonoen de FLI. 4. Biomerieux Seminar Mikrobiologie in der Veterinärmedizin. Frankfurt d) Other: (Provide webite addre or link to appropriate information) 3 Elchner MC, Liebler-Tenorio, E., Neubauer, H.: The diagnotic approach to equine glander in Germany Equine Dieae Quartely 2016, 25(1). Elchner M L-TE, Brügmann M., Melzer F. Neubauer H. : Re-appearance of glander into Wetern : clinical, laboratory and pathological finding in a German hore. OIE Bulletin 2016, 1/2016: Iahtaham KHAN, Shahzad AL, Mandy ELSCHNER, Katja MERTENS, Falk MELZER,Haroon AHMED Muhammad SAQIB, Muhammad IJAZ,Mayada GWIDA, Heinrich NEUBAUER: Evaluation of Analytical-Senitivity and -Specificity of a Commercially Available One-Step Real-Time Polymerae Chain Reaction Aay Kit for the Detection of Burkholderia mallei. Kafka Univ Vet Fak Derg x (x): in pre, 2016 DOI: /kvfd ToR 7: To provide cientific and technical training for peronnel from OIE Member Countrie To recommend the precribed and alternative tet or vaccine a OIE Standard 14. Did your laboratory provide cientific and technical training to laboratory peronnel from other OIE Member Countrie? a) Technical viit: 1 b) Seminar: 4 c) Hand-on training coure: 4 d) Internhip (>1 month): 0 Type of technical training provided (a, b, c or d) Country of origin of the expert() provided with training. participant from the correponding country b, c USA 2 b,c Chile 1 b,c Japan 2 b,c Ukraine 4 a India 15 OIE Reference Laboratory Report Activitie,
8 ToR 8: To maintain a ytem of quality aurance, bioafety and bioecurity relevant for the pathogen and the dieae concerned 15. Doe your laboratory have a Quality Management Sytem certified according to an International Standard? Quality management ytem adopted See lat year report; DIN EN ISO/IEC 17025:2005 Certificate can (PDF, JPG, PNG format) Akkreditierungurkunde_FLI_Riem-Jena-2016.pdf 16. I your laboratory accredited by an international accreditation body? Tet for which your laboratory i accredited microbiology; erology;moleculr diagnoi Accreditation body DAkkS 17. Doe your laboratory maintain a biorik management ytem for the pathogen and the dieae concerned? (See Manual of Diagnotic Tet and Vaccine for Terretrial Animal, Chapter 1.1.4) ToR 9: To organie and participate in cientific meeting on behalf of the OIE 18. Did your laboratory organie cientific meeting on behalf of the OIE? 19. Did your laboratory participate in cientific meeting on behalf of the OIE? 8 OIE Reference Laboratory Report Activitie, 2016
9 Title of event Date (mm/yy) Location Role (peaker, preenting poter, hort communication) Title of the work preented X International Equine Infectiou Dieae (IEID) Conference in Bueno Aire, Argentina between to /16 Bueno Aire, Argentina POSTER Comparative tet performance of different erological tet for glander Training Coure at NRCE, Hiar (India) on Glander 02/16 India, Hiar Speaker Diagnoi of glander ToR 10: To etablih and maintain a network with other OIE Reference Laboratorie deignated for the ame pathogen or dieae and organie regular inter-laboratory proficiency teting to enure comparability of reult 20. Did your laboratory exchange information with other OIE Reference Laboratorie deignated for the ame pathogen or dieae? 21. Wa your laboratory involved in maintaining a network with OIE Reference Laboratorie deignated for the ame pathogen or dieae by organiing or participating in proficiency tet? 22. Did your laboratory collaborate with other OIE Reference Laboratorie for the ame dieae on cientific reearch project for the diagnoi or control of the pathogen of interet? Title of the project or contract Scope Name() of relevant OIE Reference Laboratorie OIE- INTERNATIONAL CALL FOR TENDER- Tender ref.: AD/SR/2015/1885 Validation tudy of a wetern blot (WB) technique and ELISA for erological diagnoi of glander in equid for the purpoe of certifying freedom from infection in individual animal for trade or movement. CVRL Dubai ToR 11: To organie inter-laboratory proficiency teting with laboratorie other OIE Reference Laboratory Report Activitie,
10 than OIE Reference Laboratorie for the ame pathogen and dieae to enure equivalence of reult 23. Did your laboratory organie or participate in inter-laboratory proficiency tet with laboratorie other than OIE Reference Laboratorie for the ame dieae? te: See Interlaboratory tet comparion in: Laboratory Proficiency Teting at: ee point 1.3 Purpoe for inter-laboratory tet comparion 1. participating laboratorie Region() of participating OIE Member Countrie CFT glander 01/16 12 Eat CFT glander 02/16 12 Eat ToR 12: To place expert conultant at the dipoal of the OIE 24. Did your laboratory place expert conultant at the dipoal of the OIE? Kind of conultancy Location Subject (facultative) Participation of Prof. Neubauer at Glander meeting Brazil Glander 25. Additional comment regarding your report: 10 OIE Reference Laboratory Report Activitie, 2016
OIE Reference Laboratory Reports Activities
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