OIE Reference Laboratory Reports Activities

Transcription

1 OIE Reference Laboratory Reports Activities Activities in 2013 This report has been submitted : :17:14 Name of disease (or topic) for which you are a designated OIE Reference Laboratory: Campylobacteriosis Address of laboratory: Utrecht University, Faculty of Veterinary Medicine, PO box , 3508 TD Utrecht, the Netherlands Central Veterinary Institute, PO box 65, 8200 AB Lelystad, the Netherlands Tel.: Fax: address: j.wagenaar@uu.nl website: Name (including Title) of Head of Laboratory (Responsible Official): Prof. Jaap A. Wagenaar, DVM, PhD Name (including Title and Position) of OIE Reference Expert: Prof. Jaap A. Wagenaar, DVM, PhD Which of the following defines your laboratory? Check all that apply: Academic OIE Reference Laboratory Reports Activities,

2 ToR: To use, promote and disseminate diagnostic methods validated according to OIE Standards 1. Did your laboratory perform diagnostic tests for the specified disease/topic for purposes such as disease diagnosis, screening of animals for export, surveillance, etc.? (t for quality control, proficiency testing or staff training) Diagnostic Test Indicated in OIE Manual (/) Total number of test performed last year Indirect diagnostic tests Nationally Internationally Biochemical testing yes 10 0 Direct diagnostic tests Nationally Internationally Amplified Fragment Length Polymorphism (AFLP) yes PCR (Abril et al., 2007) no Pulsed Field Gel Electroforesis (PFGE) yes 15 ToR: To develop reference material in accordance with OIE requirements, and implement and promote the application of OIE Standards. To store and distribute to national laboratories biological reference products and any other reagents used in the diagnosis and control of the designated pathogens or disease. 2. Did your laboratory produce or supply imported standard reference reagents officially recognised by the OIE? 3. Did your laboratory supply standard reference reagents (non OIE-approved) and/or other diagnostic reagents to OIE Member Countries? 4. Did your laboratory produce vaccines? 5. Did your laboratory supply vaccines to OIE Member Countries? 2 OIE Reference Laboratory Reports Activities, 2013

3 ToR: To develop, standardise and validate, according to OIE Standards, new procedures for diagnosis and control of the designated pathogens or diseases 6. Did your laboratory develop new diagnostic methods validated according to OIE Standards for the designated pathogen or disease? 7. Did your laboratory develop new vaccines according to OIE Standards for the designated pathogen or disease? ToR: To provide diagnostic testing facilities, and, where appropriate, scientific and technical advice on disease control measures to OIE Member Countries 8. Did your laboratory carry out diagnostic testing for other OIE Member Countries? Name of OIE Member Country seeking assistance Date (month). samples received for provision of diagnostic support. samples received for provision of confirmatory diagnoses February, March, April, July, December Did your laboratory provide expert advice in technical consultancies on the request of an OIE Member Country? Name of the OIE Member Country receiving a technical consultancy Purpose How the advice was provided UNITED KINGDOM Advice about treatment and epidemiology of Bovine Genital Campylobacteriosis Telephone calls and UNITED STATES OF AMERICA Advice about available diagnostic tests and treatment of Bovine Genital Campylobacteriosis ToR: To carry out and/or coordinate scientific and technical studies in collaboration with other laboratories, centres or organisations 10. Did your laboratory participate in international scientific studies in collaboration with OIE Member Countries OIE Reference Laboratory Reports Activities,

4 other than the own? Title of the study Duration Purpose of the study Partners (Institutions) Whole genome sequencing of Campylobacter fetus subspecies Whole genome sequencing of Campylobacter fetus subspecies USDA Infection trial of Campylobacter fetus subspecies in cattle Pathogenicity of Campylobacter subspecies in cattle INTA Studies on pathogenicity Molecular characterisation of strains Univerisity of Graz CamVac Vaccination against Campylobacter jejuni Danish Technical University (DTU) as projectleader (Danish Research Council) CamCon Vaccination against Campylobacter jejuni and phage therapy to combat C. jejuni EU-Consortium (led by the rwegian Zoonoses Center) Campylobacter in the poultry meat production chain Descriptive epidemiology of Campylobacter in the poultry production chain in Sri Lanka Vet School in Peradeniya WHO Global Food Borne Infections Network (WHO- GSS) WHO-Capacity building program Global collaboration ToR: To collect, process, analyse, publish and disseminate epizootiological data relevant to the designated pathogens or diseases 11. Did your Laboratory collect epizootiological data relevant to international disease control? 12. Did your laboratory disseminate epizootiological data that had been processed and analysed? 13. What method of dissemination of information is most often used by your laboratory? (Indicate in the appropriate box the number by category) a) Articles published in peer-reviewed journals: Kalupahana RS, Kottawatta KS, Kanankege KS, van Bergen MA, Abeynayake P, Wagenaar JA Colonization of Campylobacter spp. in Broiler Chickens and Laying Hens Reared in Tropical Climates with Low-Biosecurity Housing. Appl Environ Microbiol.79: OIE Reference Laboratory Reports Activities, 2013

5 2. Louwen R, Horst-Kreft D, de Boer AG, van der Graaf L, de Knegt G, Hamersma M, Heikema AP, Timms AR, Jacobs BC, Wagenaar JA, Endtz HP, van der Oost J, Wells JM, Nieuwenhuis EE, van Vliet AH, Willemsen PT, van Baarlen P, van Belkum A A novel link between Campylobacter jejuni bacteriophage defence, virulence and Guillain-Barré syndrome. Eur J Clin Microbiol Infect Dis. 32(2): Smid JH, Mughini Gras L, de Boer AG, French NP, Havelaar AH, Wagenaar JA, van Pelt W Practicalities of using non-local or non-recent multilocus sequence typing data for source attribution in space and time of human campylobacteriosis. PLoS One. 8(2):e Van der Graaf, Linda, Marcel A. P. van Bergen, Fimme J. van der Wal, Albert G. de Boer, and Jaap A. Wagenaar Evaluation of molecular assays for identification Campylobacter fetus species and subspecies and development of a C. fetus specific real-time PCR assay. J Microbiol Methods. 95(1): Ewa Pacholewicz, Arno Swart, Len J. A. Lipman, Jaap A. Wagenaar, Arie H. Havelaar, Birgitta Duim Propidium monoazide does not fully inhibit the detection of dead Campylobacter on broiler chicken carcasses by qpcr. J Microbiol Methods. 95(1): Patrick M, Gilbert MJ, Blaser M, Lim K, Tauxe RV, Wagenaar JA, Fitzgerald C Human Campylobacter fetus subsp. testudinum infections. Emerg Infect Dis. 19(10) Lapo Mughini Gras, Joost H. Smid, Jaap A. Wagenaar, Miriam G. Koene, Arie H. Havelaar, Ingrid H.M. Friesema, Nigel P. French, Carolien Flemming, Caterina Graziani, Luca Busani, Wilfrid van Pelt Increased risk for Campylobacter jejuni and C. coli infection of pet origin in dog owners and evidence for genetic association between strains causing infection in humans and their pets. Epidemiol Infect. 141(12): Jaap A. Wagenaar, Nigel P. French, Arie H. Havelaar. Preventing Campylobacter at the source why is it so difficult? Clin Infect Dis. 57(11): Lapo Mughini Gras, Joost H. Smid, Jaap A. Wagenaar, Albert de Boer, Arie H. Havelaar, Ingrid H.M. Friesema, Nigel P. French, Caterina Graziani, Luca Busani, Wilfrid van Pelt. Campylobacteriosis in travellers returning to The Netherlands: multilocus sequence types, risk factors, and evidence for person-to-person transmission of exotic strains in domestically acquired infections. Accepted Epidemiology and Infection. 10. Gilbert MJ, Miller WG, Yee E, Blaser MJ, Wagenaar JA, Duim B Complete Genome Sequence of Campylobacter fetus subsp. testudinum Strain T. Genome Announc. 1(6). pii: e Jaap A. Wagenaar, Marcel A.P. van Bergen, Martin J. Blaser, Robert V. Tauxe, Diane G. Newell, Jos P.M. van Putten. Campylobacter fetus infections in humans: exposure and disease. Accepted for publication. Clin Infect Dis. b) International conferences: 4 17th International Workshop on Campylobacter, Helicobacter and Related Organisms (CHRO2013) September 2013, Aberdeen, UK. ASM 113th General Meeting, May Denver, Co, US. Med-Vet-Net Association Conference One Health, One Medicine: sharing challenges for combating zoonoses June, Copenhagen, Denmark. CamCon novel approaches to control Campylobacter in primary poultry production. Safefood Campylobacter Knowledge Network, Ireland c) National conferences: 2 The Scientific Spring Meeting. Royal Dutch Society of Microbiology (KNMV) and the Dutch Society of Medical Microbiology. Arnhem, the Netherlands april 2013 Veterinary Science Day 2013, 14 vember d) Other: (Provide website address or link to appropriate information) 0 ToR: To provide scientific and technical training for personnel from OIE Member OIE Reference Laboratory Reports Activities,

6 Countries To recommend the prescribed and alternative tests or vaccines as OIE Standards 14. Did your laboratory provide scientific and technical training to laboratory personnel from other OIE Member Countries? a) Technical visits: 0 b) Seminars: 5 c) Hands-on training courses: 0 d) Internships (>1 month): 0 Type of technical training provided (a, b, c or d) Country of origin of the expert(s) provided with training. participants from the corresponding country b Spain (host) appr 8 participating countries (40 participants) b US (host) appr 5 participating countries (appr 5 participants) b Beijing (host) appr. 4 participating countries (5 participants) b Colombia (host) appr 14 part countries (40 participants) b Colombia (host) appr 10 countries, (40 participants) ToR: To maintain a system of quality assurance, biosafety and biosecurity relevant for the pathogen and the disease concerned 15. Does your laboratory have a Quality Management System certified according to an International Standard? Quality management system adopted ISO 9001 and ISO Is your laboratory accredited by an international accreditation body? 17. Does your laboratory maintain a biorisk management system for the pathogen and the disease concerned? (See Manual of Diagnostic Tests and Vaccines for Terrestrial Animals 2012, Chapter or Manual of Diagnostic Tests for Aquatic Animals 2012, Chapter 1.1.1) 6 OIE Reference Laboratory Reports Activities, 2013

7 ToR: To organise and participate in scientific meetings on behalf of the OIE 18. Did your laboratory organise scientific meetings on behalf of the OIE? 19. Did your laboratory participate in scientific meetings on behalf of the OIE? ToR: To establish and maintain a network with other OIE Reference Laboratories designated for the same pathogen or disease and organise regular inter-laboratory proficiency testing to ensure comparability of results 20. Did your laboratory exchange information with other OIE Reference Laboratories designated for the same pathogen or disease? 21. Was your laboratory involved in maintaining a network with OIE Reference Laboratories designated for the same pathogen or disease by organising or participating in proficiency tests? 22. Did your laboratory collaborate with other OIE Reference Laboratories for the same disease on scientific research projects for the diagnosis or control of the pathogen of interest? ToR: To organise inter-laboratory proficiency testing with laboratories other than OIE Reference Laboratories for the same pathogens and diseases to ensure equivalence of results 23. Did your laboratory organise or participate in inter-laboratory proficiency tests with laboratories other than OIE Reference Laboratories for the same disease? te: See Interlaboratory test comparisons in: Laboratory Proficiency Testing at: see point 1.3 OIE Reference Laboratory Reports Activities,

8 Purpose for inter-laboratory test comparisons 1. participating laboratories Region(s) of participating OIE Member Countries Proficiency testing for National Laboratories in NL 18 Africa Americas Asia and Pacific Europe Middle East ToR: To place expert consultants at the disposal of the OIE 24. Did your laboratory place expert consultants at the disposal of the OIE? Kind of consultancy Location Subject (facultative) Regional Seminar for OIE Focal Points on Animal Production Food Safety Servia Campylobacter Seminar for the OIE National Focal Points for Animal Production Food Safety Columbia Campylobacter: food safety aspects and interventions 25. Additional comments regarding your report: 8 OIE Reference Laboratory Reports Activities, 2013