OIE Reference Laboratory Reports Activities
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1 OIE Reference Laboratory Reports Activities Activities in 2015 This report has been submitted : :54:54 Name of disease (or topic) for which you are a designated OIE Reference Laboratory: Enzootic bovine leukosis Address of laboratory: Institute of Virology An den Tierkliniken Leipzig GERMANY Tel.: Fax: address: Thomas.vahlenkamp@uni-leipzig.de Website: Name (including Title) of Head of Laboratory (Responsible Official): Prof. Dr. Dr. Thomas Vahlenkamp Director Institute of Virology Faculty of Veterinary Medicine University of Leipzig Name (including Title and Position) of OIE Reference Expert: Prof. Dr. Dr. Thomas Vahlenkamp Director Institute of Virology Which of the following defines your laboratory? Check all that apply: Academic OIE Reference Laboratory Reports Activities,
2 ToR 1: To use, promote and disseminate diagnostic methods validated according to OIE Standards 1. Did your laboratory perform diagnostic tests for the specified disease/topic for purposes such as disease diagnosis, screening of animals for export, surveillance, etc.? (t for quality control, proficiency testing or staff training) Diagnostic Test Indicated in OIE Manual (/) Total number of test performed last year Indirect diagnostic tests Nationally Internationally ELISA 0 24 Immunofluorescence assay (IFA) 0 12 Direct diagnostic tests Nationally Internationally real time PCR ToR 2: To develop reference material in accordance with OIE requirements, and implement and promote the application of OIE Standards. To store and distribute to national laboratories biological reference products and any other reagents used in the diagnosis and control of the designated pathogens or disease. 2. Did your laboratory produce or supply imported standard reference reagents officially recognised by the OIE? NOTE: Currently, there are 22 laboratories that produce Standard Reference Reagents officially recognised by the OIE for 19 diseases/pathogens. Please click the following link to the list of OIE-approved International Standard Sera: If the reagent is not listed on this page, it is NOT considered OIE-approved. The next two questions allow you to indicate non-oie-approved diagnostic reagents. 2 OIE Reference Laboratory Reports Activities, 2015
3 Disease Test Available from Enzootic bovine leukosis Agar gel immunodiffusion Prof. Thomas Vahlenkamp Institute of Virology, Centre for Infectious Diseases, Faculty of Veterinary Medicine Leipzig University, An den Tierkliniken Leipzig, Germany Tel: (49-341) Fax: (49-341) Type of reagent available Related diagnostic test Produced/ Supply imported Amount supplied nationally (ml, mg) Amount supplied internationally (ml, mg) Name of recipient OIE Member Countries OIE EBL-Reference Serum E05 AGID ELISA Supply GERMANY OIE EBL-Reference Serum E05 AGID ELISA Supply SERBIA OIE EBL-Reference Serum E05 AGID ELISA Supply KOREA (REP. OF) 3. Did your laboratory supply standard reference reagents (non OIE-approved) and/or other diagnostic reagents to OIE Member Countries? 4. Did your laboratory produce vaccines? 5. Did your laboratory supply vaccines to OIE Member Countries? ToR 3: To develop, standardise and validate, according to OIE Standards, new procedures for diagnosis and control of the designated pathogens or diseases 6. Did your laboratory develop new diagnostic methods validated according to OIE Standards for the designated pathogen or disease? 7. Did your laboratory develop new vaccines according to OIE Standards for the designated pathogen or disease? OIE Reference Laboratory Reports Activities,
4 Name of the new test or diagnostic method or vaccine developed Description and References (Publication, website, etc.) real time PCR Heenemann et al. (2012) Development of a Bovine leukemia virus polymerase gene based real-time polymerase chain reaction and comparison with an envelope gene based Assay. J. Vet. Diagn. Invest. 24: ToR 4: To provide diagnostic testing facilities, and, where appropriate, scientific and technical advice on disease control measures to OIE Member Countries 8. Did your laboratory carry out diagnostic testing for other OIE Member Countries? Name of OIE Member Country seeking assistance Date (month). samples received for provision of diagnostic support. samples received for provision of confirmatory diagnoses DENMARK 02/03/ SERBIA KAZAKHSTAN FRANCE 06/07/07/10/11/ Did your laboratory provide expert advice in technical consultancies on the request of an OIE Member Country? Name of the OIE Member Country receiving a technical consultancy Purpose How the advice was provided FRANCE Problems in detecting EBL specific antibodies in milk by phone by by personal visit SERBIA advice which Commercial test to be used for antibody screenning by URUGUAY How to validate diagnostic tests for EBL by BULGARIA How to test EBL-specific antibodies by 4 OIE Reference Laboratory Reports Activities, 2015
5 ToR 5: To carry out and/or coordinate scientific and technical studies in collaboration with other laboratories, centres or organisations 10. Did your laboratory participate in international scientific studies in collaboration with OIE Member Countries other than the own? Title of the study Duration Purpose of the study Partners (Institutions) Ring trial for EBL PCRbased diagnosis 06/2015 compare different PCR methods (quantitative detection) in total 6 institutions: 1) Poland 2) UK 3) Germany 4) Belgium 5) Japan 6) Argentina ToR 6: To collect, process, analyse, publish and disseminate epizootiological data relevant to the designated pathogens or diseases 11. Did your Laboratory collect epizootiological data relevant to international disease control? 12. Did your laboratory disseminate epizootiological data that had been processed and analysed? 13. What method of dissemination of information is most often used by your laboratory? (Indicate in the appropriate box the number by category) a) Articles published in peer-reviewed journals: 1 Depner, K., P. Have, A. De Koeijer, J. Kuzmak, T.W Vahlenkamp, A. Viltrop and L. Willems (2015): EFSA AHAW Panel (EFSA Panel on Animal Health and Welfare). Scientific opinion on enzootic bovine leukosis. EFSA Journal 13(7): 4188, 63 pp. doi: /j.efsa ISSN: b) International conferences: 1 European Food Safety Agency (EFSA): Panel on Animal Health and Welfare. Scientific opinion on enzootic bovine leukosis c) National conferences: 1 Presentation: Stendaler Symposium - Tierseuchenbekämpfung, Tierschutz und Tierarzneimittel bei der Tierart Rind, Stendal Vahlenkamp, T.W.: Zur Epidemiologie und wirtschaftlichen Bedeutung von Enzootischer Boviner Leukose (EBL) in und außerhalb der EU d) Other: (Provide website address or link to appropriate information) 1 Meeting: OIE reference laboratories in Poland 1) National Veterinary Research Institute (NVRI), Pulawy (Poland) 2) Animal and Plant Health Agency (APHA), Weybridge (UK) OIE Reference Laboratory Reports Activities,
6 3) Institute of Virology, University of Leipzig (Germany) ToR 7: To provide scientific and technical training for personnel from OIE Member Countries To recommend the prescribed and alternative tests or vaccines as OIE Standards 14. Did your laboratory provide scientific and technical training to laboratory personnel from other OIE Member Countries? ToR 8: To maintain a system of quality assurance, biosafety and biosecurity relevant for the pathogen and the disease concerned 15. Does your laboratory have a Quality Management System certified according to an International Standard? Explain Quality Management System in adoption process or currently in place We are currently in the process to aquire a QM certificate 16. Is your laboratory accredited by an international accreditation body? 17. Does your laboratory maintain a biorisk management system for the pathogen and the disease concerned? (See Manual of Diagnostic Tests and Vaccines for Terrestrial Animals 2014, Chapter 1.1.3a) ToR 9: To organise and participate in scientific meetings on behalf of the OIE 18. Did your laboratory organise scientific meetings on behalf of the OIE? 19. Did your laboratory participate in scientific meetings on behalf of the OIE? 6 OIE Reference Laboratory Reports Activities, 2015
7 Title of event Date (mm/yy) Location Role (speaker, presenting poster, short communications) Title of the work presented Meeting of the OIE Reference Laboratories for EBL 06/2015 Pulawy (Poland) short communications EBL diagnosis at the reference Laboratory in Germany ToR 10: To establish and maintain a network with other OIE Reference Laboratories designated for the same pathogen or disease and organise regular inter-laboratory proficiency testing to ensure comparability of results 20. Did your laboratory exchange information with other OIE Reference Laboratories designated for the same pathogen or disease? 21. Was your laboratory involved in maintaining a network with OIE Reference Laboratories designated for the same pathogen or disease by organising or participating in proficiency tests? Purpose of the proficiency tests: 1 Role of your Reference Laboratory (organiser/ participant). participants Participating OIE Ref. Labs/ organising OIE Ref. Lab. quantitative real time PCR Participant 6 1) National Veterinary Research Institute (NVRI) (Poland) 2) Animal and Plant Health Agency (APHA) (UK) 3) Institute of Virology University of Leipzig (Germany) 1 validation of a diagnostic protocol: specify the test; quality control of vaccines: specify the vaccine type, etc. 22. Did your laboratory collaborate with other OIE Reference Laboratories for the same disease on scientific research projects for the diagnosis or control of the pathogen of interest? Title of the project or contract Scope Name(s) of relevant OIE Reference Laboratories Exchange protocols for immunofluorescence assays (IFA) Establishment of EBLspecific IFA National Veterinary Research Institute (NVRI) (Poland) OIE Reference Laboratory Reports Activities,
8 ToR 11: To organise inter-laboratory proficiency testing with laboratories other than OIE Reference Laboratories for the same pathogens and diseases to ensure equivalence of results 23. Did your laboratory organise or participate in inter-laboratory proficiency tests with laboratories other than OIE Reference Laboratories for the same disease? te: See Interlaboratory test comparisons in: Laboratory Proficiency Testing at: see point 1.3 Purpose for inter-laboratory test comparisons 1. participating laboratories Region(s) of participating OIE Member Countries EBL detection by ELISA and PCR 1 Africa Americas Asia and Pacific Europe Middle East ToR 12: To place expert consultants at the disposal of the OIE 24. Did your laboratory place expert consultants at the disposal of the OIE? 25. Additional comments regarding your report: 8 OIE Reference Laboratory Reports Activities, 2015
OIE Reference Laboratory Reports Activities
OIE Reference Laboratory Reports Activities Activities in 2016 This report has been submitted : 2017-01-13 10:41:13 Name of disease (or topic) for which you are a designated OIE Reference Laboratory: Enzootic
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OIE Reference Laboratory Reports Activities Activities in 2016 This report h been submitted : 2017-01-11 18:55:37 Name of disee (or topic) for which you are a designated OIE Reference Laboratory: Brucellosis
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OIE Reference Laboratory Reports Activities Activities in 2016 This report has been submitted : 2017-01-04 14:57:02 Name of disease (or topic) for which you are a designated OIE Reference Laboratory: Contagious
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