CERMES (Pasteur Institute of Niger)

Size: px

Start display at page:

Download "CERMES (Pasteur Institute of Niger)"

Albert McDonald
5 years ago
Views:

1 CERMES (Pasteur Institute f Niger) The missins: a basic, applied and peratinal, in medical and health fields; Supprt fr natinal institutins and services and pssibly t any ther state, fr everything related t labratry medicine and public health; The expertise f risks and evaluatin f prgrams against endemic diseases; Training f health cadres, dmestic r freign. The CERMES Branch is assured since March 2012 by Odile Ouwe Missi-OUKEM 1. Bilgy (Bacterilgy- Virlgy) (UBIOL) 2. Medical Entmlgy (EMU) 3. Parasitlgy (UPARA) 4. Epidemilgy-Health-Envirnment-Climate (EUSEC) Three main themes Bacterial meningitis 1. Impact f MenAfriVac vaccine 2. Asymptmatic Prtage 3. Negative CSF 4. Mrtality 5. Aftermath 6. Infectins pneumcccal Malaria 1. Genetic diversity f parasites and anphèliennees ppulatins 2. Efficiency based cmbinatin Artémisineine 3. Impact f massive campaigns f distributin f msquit nets (LLINs) 4. Cmparisn f methds f distributin f LLINs Relatinships Health-Envirnment-Climate 1. Analysis f spatitempral meningitis 2. Special features f urban malaria 3. Threshlds Alerts A New Theme Respiratry Infectin Aigues IRAs (in develpment) Other issues f interest 1. Antimalarial Resistance 2. Resistance t insecticides 3. Antimicrbial Resistance

2 Natinal Reference Labratries (NRL) 1. Diagnsis and Surveillance f Meningitis 2. Diagnsis and Surveillance f Influenza 3. Diagnsis and Mnitring f Chlera and ther Gastrenteritis 4. Surveillance f Antimalarial Drug Resistance 5. Crdinatin f the Natinal Netwrk f Labratries A strip prductin unit Prductin f strips fr the rapid diagnsis f meningitis A, C, W, Y Meningitis Surveillance f meningitis in Niger Micrbilgical mnitring f meningitis Rapid diagnstic test activities Cerebr-spinal Study f negative fluid samples Evaluate the diagnstic cnduct face a suspected case f meningitis, perfrmed in the medical curses and knw the ptential pathgens invlved Atres than thse detected by surveillance. Studies sequelae after meningitis The main bjective is t estimate the incidence f bacterial meningitis sequelae in Niger in the range f three t six mnths after the meningitis episde, and the relative risk cmpared t the general ppulatin. Study and carry immunity (MenAfriCar) The bjectives are: The identificatin f carriers f meningcccal meningitis in cuntries f the meningitis belt Africa. Characterizatin f prting dynamic amng the hlders f families and what will be the impact f vaccinatin with the new cnjugate vaccine A. The investigatin f the relatinship between the carriage f ptentially pathgenic meningccci and Neisseria spnnpathgenic befre and after vaccinatin with the new cnjugate vaccine A. This research prject initiated by Brian Greenwd (Lndn Schl f Hygiene & Trpical Medicine) and funded by the Wellcme Trust / B. Gates Fundatin and assciate n seven cuntries in the African meningitis belt: Chad, Ethipia, Gambia, Ghana, Mali, Nigeria and Niger (with tw assciated cuntries: Burkina Fas and Senegal). Internatinal Cllabratins Natinal Centre f Reference and Neisseria Neisseria Unit, Institute Pasteur, Paris: Dr Muhamed Taha K Technical Platfrm PT5, Institute Pasteur, Paris: Dr Farida Nat Preventive Medicine Assciatin, Paris: Dr. Judith Muller, Betty Lafurcade, Dr. Alfred Da Sylva

3 WHO Cllabratin Centre fr meningcccal IMTSSA / Le Phar, Marseille: Dr Pierre Niclas Health Prtectin Agency (Manchester Medical Micrbilgy Partnership), Manchester, UK: Dr Ray Brrw Muraz Center, Bb Diulass, Burkina Fas: Dr Yves Trare R. Piqué Hspital (Brdeaux): Dr. Jean-Luis Keck Natinal Reference Center pneumccci, Eurpean Gerges Pmpidu Hspital, Paris Internatinal Netwrk f Pasteur Institutes (Camern, Bangui, Dakar, Ivry Cast, Paris) Malaria Head f Parasitlgy Unit: Rabiu Labb Participatin in the management f malaria cases 1. Establishment f a mnitring netwrk f P. falciparum resistance t antimalarials. 2. Equipment f a technical platfrm fr carrying ut tests in vitr and in additin mlecular in viv tests. 3. Training f health wrkers in methds f labratry diagnsis f malaria. Vectr cntrl and reductin f transmissin. 1. Intra Hme residual spraying (IRS) 2. Especially the distributin f LLINs. Evaluatin f sensitivity f vectrs t épandus insecticides and used t impregnate the nets. Evaluatin f the impact f PID campaigns n the transmissin and Resistances. Measuring the impact f universal cverage f LLINs in the transmissin, the parasite and species f anpheles, and finally the behavir f vectrs Vectr transmissin study in urban areas. Internatinal Cllabratins Netwrk f Pasteur Institutes (Madagascar, Cambdia, Guyana). Institute f Trpical Medicine f the Army Health Service (Marseille, France). Pasteur Institute (Paris). Massachusetts Institute f Technlgy (Bstn, USA). The areas f expertise are: Mlecular epidemilgy f malaria. Eclgy and dynamics f vectr ppulatins. Envirnmental factrs related t the parasite prtage. Surveillance f resistance f P. falciparum t antimalarial drugs and insecticide anpheles. Bilgical diagnsis f malaria micrscpy, rapid tests and mlecular tests.

4 Training and receiving trainees. Health / envirnment-climate - Jean-Paul Mulia Pelat, MD, PhD, Epidemilgist, Head f Unit Epidemilgy / Health-Envirnment-Climate This link is quantified measure f risk crrespnding t the prbability that an individual suffers harm r harm t his health if expsed t danger especially f envirnmental rigin. Advances in statistics, epidemilgy nw allw this quantificatin. Relatinal database management systems and gegraphic infrmatin systems (GIS) allw t ptimally explit mnitring data in the study f the link between disease and the envirnment. The seasnality f meningitis and malaria In the Sahel, seasnal variatins in malaria cases are strngly related t climate variatins including rainfall. Outbreaks f meningcccal meningitis are, t, because f the marked seasnal rle f certain climatic factrs (humidity, dust) and limited t certain areas. The themes include: GIS-mnitring: health card and spatitempral distributin f meningitis Study f the link between disease and the envirnment. The activities include: develp the tls and resurces necessary fr spatial and tempral analysis f the transmissin f malaria and meningitis cllect envirnmental and climate infrmatin at scales cmpatible with health data, in time and in space and establish cllabratins with specialized agencies t identify and get the mst relevant climatic and envirnmental parameters measure the risk psed by envirnmental factrs in the ccurrence f a disease Develp training in the field f envirnmental health. Digital supprt natinal health map Niger Spatitempral distributin f meningitis Spatial and spati-tempral clusters identified during the 2002 seasn (N. meningitidis and S. pneumniae) Envirnmental health: study f the relatinship between climatic factrs / meningitis and malaria Public health

5 Flu: NRL fr the mnitring and diagnsis f influenza - Crdinatin: Jean-Paul MOULIA PELAT, PhD, Epidemilgist, Head f the Unit f Epidemilgy / Health-Climate-Envirnment Influenza surveillance in Niger The main bjectives are: The descriptin f seasnal influenza (A and B) in terms f seasnality (apprach), its gegraphic distributin and epidemilgy. Antigenic and genetic cmparisn f strains circulating in Africa (dynamic genetic diversity f influenza viruses). The measurement f antiviral resistance strains islated Internatinal Cllabratins WHO Cllabrating Centre fr Reference and n influenza viruses and ther respiratry viruses, Institute Pasteur, Paris. WHO Influenza EQAP Wrking Team, Hng Kng Training activity with tw main directins: Labratry Technician Refresher Curse Reginal thematic scientific wrkshps Mémires Master, and ingéniriat f dctral thesis Stages And memries f the Natinal Schl f Public Health and Institute f Public Health, Niamey Stages Schlars (Internatinal Yuth) During Natinal Malaria The Natinal Malaria Curse (NOC) is the result f cllabratin between the Faculty f Health Sciences f the University Abu Mumuni (FSS / UAM), the Natinal Prgram against Malaria (NMCP), the Hspital Niamey Natinal (HNN) and the Center fr Medical and Health (CERMES). The gal: train scientists and stakehlders in the fight against malaria by using internet search engines under the supervisin f a facilitatr.

The Centre for Research on Filariasis and other Tropical Diseases (CRFilMT) Joseph KAMGNO

The Centre for Research on Filariasis and other Tropical Diseases (CRFilMT) Joseph KAMGNO The Centre fr Research n Filariasis and ther Trpical Diseases (CRFilMT) Jseph KAMGNO Plan Histry Presentatin Infrastructure Main research tpics Main achievements CANTAM Netwrk 2 Histry CRFilMT was created