OIE Collaborating Centers Reports Activities

Transcription

1 OIE Collaborating Centers Reports Activities Activities in 2014 This report has been submitted : :17:10 Title of collaborating centre: Veterinary Biologicals Biobank Address of Collaborating Centre: (IZSLER) Via Bianchi, Brescia ITALY Tel.: Fax: address: maura.ferrari@izsler.it Website: Name of Director of Institute (Responsible Official): Prof. Stefano Cinotti (General Manager of Istituto Zooprofilattico Sperimentale della Lombardia e dell'emilia Romagna - IZSLER" Name (including Title and Position) of Head of the Collaborating Centre (formally OIE Contact Point): Dr. Maura Ferrari, Head of the OIE Collaborating Centre for "Veterinary Biological Biobank Network" Name of writer: Maura Ferrari OIE Collaborating Centers Reports Activities,

2 ToR: To provide services to the OIE, in particular within the region, in the designated specialty, in support of the implementation of OIE policies and, where required, seek for collaboration with OIE Reference Laboratories ToR: To identify and maintain existing expertise, in particular within its region 1. Activities as a centre of research, expertise, standardisation and dissemination of techniques within the remit of the mandate given by the OIE Disease control Leishmaniasis Control Control of the spread of disease Epidemiology, surveillance, risk assessment, modelling Regional surveillance of West Nile virus (WNV) To detect and survey the circulation of WNV in monitored area Training, capacity building Organization of meetings and scientific events Organization of the annual CEROVEC s congress Zoonoses Leishmaniasis surveillance Study of the disease prevalence and prevention of zoonotic risk Aquatic animal diseases Anisakiasis surveillance Evaluation of the presence of Anisakis in fish Diagnosis, biotechnology and laboratory 2 OIE Collaborating Centers Reports Activities, 2014

3 Basic activity: histopathological diagnosis, histochemical and immunohistochemical exams The National Reference Centre for Veterinary and Comparative Oncology is responsible for domestic animal tumor tissue samples collection and analyses (field samples). Formalin-fixed neoplastic organs and tissues are sent by local veterinary surgeons to the Centre for histologic diagnosis. Histochemical and immunohistochemical exams are performed to confirm the diagnosis. Food safety Anisakiasis surveillance Evaluation of the presence of Anisakis in the chain of fishery products Other (Name the category) Network of Biobank of Veterinary Biological Resources Collect, control, store and distribute biological resources of interest in Veterinary field ToR : To propose or develop methods and procedures that facilitate harmonisation of international standards and guidelines applicable to the designated specialty 2. Proposal or development of any procedure that will facilitate harmonisation of international regulations applicable to the surveillance and control of animal diseases, food safety or animal welfare Proposal title /Content Applicable area IZSLER Biobank: Headquarter Collect different types of biological resources; harmonize the development of biobanks involved in the network Surveillance and control of animal diseases Food safety Animal welfare ToR: To establish and maintain a network with other OIE Collaborating Centres designated for the same specialty, and should the need arise, with Collaborating Centres in other disciplines ToR: To carry out and/or coordinate scientific and technical studies in collaboration with other centres, laboratories or organisations 3. Did your Collaborating Centre maintain a network with other OIE Collaborating Centres (CC), Reference Laboratories (RL), or organisations designated for the same specialty, to coordinate scientific and technical studies? OIE Collaborating Centers Reports Activities,

4 Name of OIE CC/RL/other organisation(s) Location Region of networking Centre Purpose OIE Reference Centre for Avian influenza and Necastle virus IZS Venezie (Padova, IT) Africa Americas Asia and Pacific Europe Middle East To collect viruses and samples from infected animals to be used for diagnosis, epidemiologic surveys and prevention strategies 4. Did your Collaborating Centre maintain a network with other OIE Collaborating Centres, Reference laboratories, or organisations in other disciplines, to coordinate scientific and technical studies? Name of OIE CC/RL/other organisation(s) Location Region of networking Centre Purpose OIE Reference Centre for Avian influenza and Necastle virus IZS Venezie (Padova, IT) Africa Americas Asia and Pacific Europe Middle East To increase the cooperation on virus detection and cultivation on biological systems alternative to the standard chicken embryos ToR: To place expert consultants at the disposal of the OIE. 5. Did your Collaborating Centre place expert consultants at the disposal of the OIE? Name of expert Kind of consultancy Subject Maura Ferrari Standardization of quality controls for pathogens to be collected in a biobank Development of biobanks ToR: To provide, within the designated specialty, scientific and technical training to personnel from OIE Member Countries 6. Did your Collaborating Centre provide scientific and technical training, within the remit of the mandate given by the OIE, to personnel from OIE Member Countries? a) Technical visits: 0 b) Seminars: 2 c) Hands-on training courses: 0 4 OIE Collaborating Centers Reports Activities, 2014

5 d) Internships (>1 month): 1 Veterinary Biologicals Biobank - Istituto Zooprofilattico Sperimentale de Type of technical training provided (a, b, c or d) Content Country of origin of the expert(s) provided with training No. participants from the corresponding country b The food risk related to toxoplasmosis Catania, Italy 55 ToR: To organise and participate in scientific meetings and other activities on behalf of the OIE 7. Did your Collaborating Centre organise or participate in the organisation of scientific meetings on behalf of the OIE? National/International Title of event Co-organiser Date (mm/yy) Location No. Participants National Training course on diagnosis of equine diseases April 2014 Palermo, Italy 10 ToR: To collect, process, analyse, publish and disseminate data and information relevant to the designated specialty 8. Publication and dissemination of any information within the remit of the mandate given by the OIE that may be useful to Member Countries of the OIE a) Articles published in peer-reviewed journals: A chapter entitled "Veterinary Biobank facility: development and management for diagnostic and research purposes". Tina Lombardo, Silvia Dotti, Riccardo Villa, Stefano Cinotti, Maura Ferrari of the MiMB Springer's volume "Molecular Diagnostics in Laboratory Veterinary Practice. in press. 2. Ciani E, Crepaldi P, Nicoloso L, Lasagna E, Sarti FM, Moioli B, Napolitano F, Carta A, Usai G, D'Andrea M, Marletta D, Ciampolini R, Riggio V, Occidente M, Matassino D, Kompan D, Modesto P, Macciotta N, Ajmone-Marsan P, Pilla F. Genome-wide analysis of Italian sheep diversity reveals a strong geographic pattern and cryptic relationships between breeds. Anim Genet Apr;45(2): doi: /age Orrù CD, Favole A, Corona C, Mazza M, Manca M, Groveman BR, Hugson AG, Acutis PL, Caramelli M, Zanusso G, Casalone C, Caughey B (2014). Detection and discrimination of classical BSE and BASE by RT-QuIC Journal of Clinical Microbiology (Under Review) 4. Schiffer D, Valentini C, Melcarne A, Mellai M, Prodi E, Carrara G, Denysenko T, Junemann C, Casalone C, Corona C, Caldera V, Annovazzi L, Piazzi A, Cassoni P, Senetta R, Fania P, Cistaro A. Book title: CNS tumor Chapter title: Spatial relationships of MR imaging and positron emission tomography with phenotype, genotype and tumor stem cell generation in glioblastoma multiforme. In CNS tumor ISBN Book edited by: Lee Roy Morgan 5. Berrone E, Corona C, Mazza M, Vallino Costassa E, Lo Faro M, Properzi F, Maurella C, Caramelli M, Deregibus OIE Collaborating Centers Reports Activities,

6 MC, Camussi G, Casalone C (2014) "Prion protein in exosome derived from ovine plasma" articolo sottomesso a Journal of Virology (Under Review) 6. Pintore MD, Ceballos L, Iulini B, Tomassone L, Pautasso A, Corbellini D, Rizzo F, Mandola ML, Bardelli M, Peletto S, Acutis PL, Mannelli A, Casalone C. (2014) Detection of Invasive Borrelia burgdorferi Strains in North-Eastern Piedmont, Italy. Zoonoses Public Health. Sep 15. doi: /zph Rizzo F, Cerutti F, Ballardini M, Mosca A, Vitale N, Radaelli MC, Desiato R, Prearo M, Pautasso A, Casalone C, Acutis P, Peletto S, Mandola ML. (2014). Molecular characterization of flaviviruses from field-collected mosquitoes in northwestern Italy, Parasit Vectors. Aug 26;7:395. doi: / Casalone C, Mazzariol S, Pautasso A, Di Guardo G, Di Nocera F, Lucifora G, Ligios C, Franco A, Fichi G, Cocumelli C, Cersini A, Guercio A, Puleio R, Goria M, Podesta M, Marsili L, Pavan G, Pintore A, De Carlo E, Eleni C, Caracappa S. (2014). Cetacean strandings in Italy: an unusual mortality event along the Tyrrhenian Sea coast in Dis Aquat Organ Apr 23;109(1):81-6. doi: /dao Ceballos LA, Pintore MD, Tomassone L, Pautasso A, Bisanzio D, Mignone W, Casalone C, Mannelli A. (2014). Habitat and occurrence of ixodid ticks in the Liguria region, northwest Italy. Exp Appl Acarol.Sep;64(1): doi: /s y. Epub 2014 Mar 30. Erratum in: Exp Appl Acarol Sep;64(1): Capra E, Cremonesi P, Cortimiglia C, Bignoli G, Ricchi M, Moroni P, Pesce A, Luini M, Castiglioni B. Simultaneous identification by multiplex PCR of major Prototheca spp. isolated from bovine and buffalo intramammary infection and bulk tank. Lett Appl Microbiol Dec;59(6): Ferrari A., Campanella C., Vito G., Crescio I., Ferrari M., Ratto A., The National Reference Centre of Veterinary and Comparative Oncology: Veterinary Biobank, International Journal of Comparative Oncology, in press. 12.Gatti M., Wurth R, Pattarozzi A., Ratto A., Campanella C., Vito G., Maniscalco L., De Maria R., Barbieri F., Villa V., Thellung S., Corsaro A., Nizzari M., Bajetto A., Ferrari A and Florio T. Canine osteosarcoma cell lines contain stem-like cancer cells: biological and pharmacological characterization, International Journal of Comparative Oncology, in press 13. Calzolari M, Monaco F, Montarsi F, Bonilauri P, Ravagnan S, Bellini R, Cattoli G, Cordioli P, Cazzin S, Pinoni C, Marini V, Natalini S, Goffredo M, Angelini P, Russo F, Dottori M, Capell G, Savini G. New incursions of West Nile virus lineage 2 in Italy in 2013: the value of the entomological surveillance as early warning system. Vet Ital Jul-Sep;49(3): Calzolari M, Bonilauri P, Bellini R, Albieri A, Defilippo F, Tamba M, Tassinari M, Gelati A, Cordioli P, Angelini P, Dottori M. Usutu virus persistence and West Nile virus inactivity in the Emilia-Romagna region (Italy) in PLoS One May 7;8(5):e doi: /journal.pone Print Calzolari M, Gaibani P, Bellini R, Defilippo F, Pierro A, Albieri A, Maioli G, Luppi A, Rossini G, Balzani A, Tamba M, Galletti G, Gelati A, Carrieri M, Poglayen G, Cavrini F, Natalini S, Dottori M, Sambri V, Angelini P, Bonilauri P. Mosquito, bird and human surveillance of West Nile and Usutu viruses in Emilia-Romagna Region (Italy) in PLoS One. 2012;7(5):e doi: /journal.pone Epub 2012 May Calzolari M, Bonilauri P, Bellini R, Albieri A, Defilippo F, Maioli G, Galletti G, Gelati A, Barbieri I, Tamba M, Lelli D, Carra E, Cordioli P, Angelini P, Dottori M. Evidence of simultaneous circulation of West Nile and Usutu viruses in mosquitoes sampled in Emilia-Romagna region (Italy) in PLoS One Dec 15;5(12):e doi: /journal.pone Calzolari M, Bonilauri P, Bellini R, Caimi M, Defilippo F, Maioli G, Albieri A, Medici A, Veronesi R, Pilani R, Gelati A, Angelini P, Parco V, Fabbi M, Barbieri I, Lelli D, Lavazza A, Cordioli P, Dottori M. Arboviral survey of mosquitoes in two northern Italian regions in 2007 and Vector Borne Zoonotic Dis Nov;10(9): doi: /vbz Epub 2010 Apr Torina A., Moreno-Cid J.A., Blanda V., Fernández de Mera I.G., Pérez de la Lastra J.M., Scimeca S., Blanda M., Scariano M. E., Briganò S., Disclafani R., Piazza A., Vicente J., Gortázar C., Caracappa S., Lelli R.C., de la Fuente J. (2014) Control of tick infestations and pathogen prevalence in cattle and sheep farms vaccinated with the recombinant Subolesin-Major Surface Protein 1a chimeric antigen. Parasites & Vectors 7: Spada E., Proverbio D., Galluzzo P., Perego R., Bagnagatti De Giorgi G., Roggero N., Caracappa S. (2014) 6 OIE Collaborating Centers Reports Activities, 2014

7 Frequency of Piroplasms Babesia microti and Cytauxzoon felis in Stray Cats from Northern Italy. BioMed Research International 2014 doi: /2014/ Torina, A., Blanda V., Antoci F., Scimeca S., D Agostino R., Scariano M.E., Piazza A., Galluzzo P., Giudice E. and Caracappa S. (2013) A Molecular Survey of Anaplasma spp., Rickettsia spp., Ehrlichia canis and Babesia microti in Foxes and Fleas from Sicily. Transboundary and Emerging Diseases. 60 (Suppl. 2) Spada E., Proverbio D., Galluzzo P., Della Pepa A., Perego R., Bagnagatti De Giorgi G., Ferro E. (2014) Molecular study on selected vector-borne infections in urban stray colony cats in northern Italy. J Feline Med and Surg 16(8): Migliazzo A, Vitale F, Calderone S, Puleio R, Binanti D, Abramo F. Feline leishmaniasis: a case with a high parasitic burden. Vet Dermatol Oct 18. doi: /vde [Epub ahead of print] PubMed PMID: Castelli G, Galante A, Lo Verde V, Migliazzo A, Reale S, Lupo T, Piazza M, Vitale F, Bruno F. Evaluation of two modified culture media for Leishmania infantum cultivation versus different culture media. J Parasitol Apr;100(2): doi: / Epub 2013 Dec 18. PubMed PMID: Ceccarelli M, Galluzzi L, Migliazzo A, Magnani M. Detection and characterization of Leishmania (Leishmania) and Leishmania (Viannia) by SYBR green-based real-time PCR and high resolution melt analysis targeting kinetoplast minicircle DNA. PLoS One Feb 13;9(2):e doi: /journal.pone ecollection PubMed PMID: ; PubMedCentral PMCID: PMC Amodio E., Calamusa G., Sidoti E., Migliazzo A., Vitale F., Costantino C., Vitale F., Seroprevalence of and risk factors for Leishmania seropositivity in a sample population of Western Sicily (Italy) Epidemiology Biostatistics and Public Health , Volume 11, Number 2. NBN: urn:nbn:it:prex DOI: /9024 Published as Online First on June 3, Giammanco GM, Di Bartolo I, Purpari G, Costantino C, Rotolo V, Spoto V, Geraci G, Bosco G, Petralia A, Guercio A, Macaluso G, Calamusa G, De Grazia S, Ruggeri FM, Vitale F, Maida CM, Mammina C. Investigation and control of a Norovirus outbreak of probable waterborne transmission through a municipal groundwater system. J Water Health Sep;12(3): doi: /wh PubMed PMID: Recovery of Anisakid larvae by means of chloro-peptic digestion and proposal of the method for the official control P. Fraulo, C. Morena, A. Costa. Acta Parasitologica 59 (4)2014: Putative hybrids between two Anisakis cryptic species: molecular genotyping using High Resolution Melting (2014) S. Cavallero, A. Costa, S. Caracappa, B. Gambetta, S. D'Amelio. Experimental Parasitology 146 (2014): Anisakidae in fishing products sold in Sicily V. Ferrantelli, A. Cicero, A. Costa, A. Alongi, P. Palumbo, S. Graci, G. Giangrosso. Italian Journal Food Safety 2014: Vol 3: 1719; Il Centro di Referenza Nazionale per le Anisakiasi: attività e competenze A. Costa, V. Ferrantelli. Eurofishmarket Magazine n n.1; b) International conferences: 16 European, Middle Eastern and African Society for Biopreservation and Biobanking (ESBB): Leipzig, Germany, October )Regenerative medicine: need of a controlled and long-lasting cryopreservation. Renzi, S., Dotti, S., Lombardo, T., Ferrari, M. and Villa, R. Istituto Zooprofilattico Sperimentale della Lombardia e dell Emilia Romagna, Brescia, Italy 2)Development of the Italian Veterinary biobank network Lombardo, T., Villa, R., Dotti, S., Renzi, S., Ferrari, M., Cinotti, S. Istituto Zooprofilattico Sperimentale della Lombardia e dell Emilia Romagna, Brescia, Italy 3) OIE International Meeting, Seoul, October 2014 International reference materialresults of the OIE survey. T. Lombardo, R. Villa, M. Ferrari, S. Cinotti 4. TSE EURL Conference 18th-19th June Heathrow, London. Update on atypical TSE cases in Italy. 5. TSE EURL Conference 18th-19th June Heathrow, London. Nor98 like in Italy. 6. BTSF, Prevention, Control and Eradication of TSEs. Utrecht, Giugno 2014, Utrecht, 30 settembre- 3 ottobre 2014; Lubiana 4-7 novembre 2014; Lisbona, novembre BSE/TSE EFSA Network, Breeding programmes for resistance to Classical scrapie: ideal characteristics and expected impact on Classical scrapie. Parma 7-8 Ottobre rd Iberian Congress on Prions, Zaragoza (Spain), 2-3 December Experimental transmission of classical and atypical BSE in goats. 9. Ferrari A., Florio T., Gatti M., Vito G., Campanella C., Barbieri F., Maniscalco L., De Maria R., Buracco P., Ratto A., Biological characterization and sensitivity to metformin of cancer stem-like cells from canine osteosarcoma OIE Collaborating Centers Reports Activities,

8 cell lines, European Society of Veterinary Oncology (ESVONC) Annual Congress, Vienna, may. 10. Ferrari A., Porcario C., Barbieri F., Thellung S., Wurth R., Campanella C., Cosma V., Vito G., Ratto A., Florio T., In vitro and in vivo metformin effects on cancer-stem like cells isolated from canine mammary carcinoma, Veterinary Cancer Society (VCS) Annual Conference, St. Louis, 9-11 october. 11. Ferrari A., Porcario C., D amore M., Campanella C., Ratto A., Vito G., Rosato G., Mizzoni V., Cavallo S., Baldi L., Galiero G., Degli Uberti B., Environment-cancer correlation: oncological casuistry in sentinel animals in Campania Region, Italy, Veterinary Cancer Society (VCS) Annual Conference, St. Louis, 9-11 october. 12. Crescio M.I., Ratto A., Campanella C., Longo A., Vito G., Ru G., Ferrari A., The network of italian laboratories for oncology in veterinary medicine: harmonizing diagnosis and data sharing, 3rd European Association of Veterinary Laboratory Diagnosticians (EAVLD) Congress, Pisa, october. 13. Caldara GF, Alongi A, Chetta M, Ferrantelli V. A histological study of eosinophilic granuloma in mice following infestation with Anisakis larvae. IJAE, Italian Journal of Anatomy and Embryology. 68 Meeting of the Italian Society of Anatomy and Histology. Vol. 119 n.1: 30, Ancona September Alongi A, Ferrantelli V, Carfì F, Caldara GF. On the morfology of Anisakis pegreffii : a comparative analysis of three microscopic techniques used to build a new parasite atlas. XIII ICOPA, International Congress of Parasitology. Camino Real Hotel of Mexico City. August 10-15, Alongi A, Caldara GF, Ferrantelli V. Anisakis pegreffii and Anisakis simplex sensu strictu in Mediterranean sea. XIII ICOPA, International Congress of Parasitology. Camino Real Hotel of Mexico City. August 10-15, Ferrantelli V, Alongi A, Platania S, Vella A and Caldara GF. Anisakids in the Mediterranean sea: statistical and health-related risks assessment. European Symposium on Food Safety (IAFP). Budapest, Hungary, May c) National conferences: 13 1) EUROPA 2014:ANIMALI E UOMINI ALLEATI CONTRO IL CANCRO (Centro di Referenza Nazionale per l Oncologia Veterinaria e Comparata (CEROVEC), Istituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle d Aosta Accademia Romena, Commissione di Medicina Comparata): Il futuro delle biobanche. Maura Ferrari. Roma, 19 Maggio )Genetic selection for resistance spongiform encephalopathies in sheep: application aspects. 2 editions: 04/04/2014, Cesenatico (FC), 25/09/2014, Baggiovara (MO). 3) Assessment quantitative BSE risk in cattle intestines and mesentery. 21/02/2014 Annual meeting of Italian Association Food Products, Milano. 4) News by EFSA on TSE risks: The new opinion on the BSE risk linked to the consumption of bovine intestine. 27/02/2014, IZS PLV, Torino. 5) Updates of the Quality System in the TSE Laboratory Diagnosis. 2 editions: 30/07/2014 and 19/12/2014, IZS PLV, Torino. 6) Ferrari A., The translational research in comparative oncology. Italian-Romanian Days of Comparative Oncology, Europe2014: Humans and animals allied against cancer. 7) Vito G., Campanella C., Ratto A., Razzuoli E., Florio T., Gatti M., Barbieri F., Maniscalco L., De Maria R., Buracco P., Ferrari A., Canine osteosarcoma cancer-stem like cells: a comparative study model in oncology, 27th Annual Conference of Italian Association of Cell Cultures (ONLUS-AICC), Verona, november. 8) Blanda V., Lelli R.C., Currò V., Randazzo K., D Agostino R., Giudice E., Caracappa S., Torina A. (2014) A new Taqman real time pcr targeting the OmpA gene for Rickettsia conorii identification 3rd European EAVLD (European Association of Veterinary Laboratory Diagnosticians) Congress - Pisa (Italy), October 12-15, 2014 Pag ) Blanda V., Lelli R., Caracappa S., Cacioppo T., Scarpulla M., Salvato L., Rizzo F., Casalone C., Tomassone L., Torina A. (2014) Phylogenetic analysis of Rickettsia pathogens present in Italy. LXVIII SISVET Congress, SICV Congress, XI AIPVET Congress e XII SIRA Congress. Pisa june ) Torina A., Crucitti D., Di Pasquale C., Marino F., De Maria C., Tarantino V., Randazzo K., Blanda V., Caracappa S. (2014) Molecular detection of tick-borne pathogens in sicilian wild animals. XXVIII SoIPa National Congress Roma june ) Torina A., Alaimo A., Blanda V., Giudice E., D Agostino R., Caracappa S., Lelli R. (2014) Molecular identification of rickettsia pathogens from stray cats and dogs and their fleas. XXVIII SoIPa National Congress Roma june 8 OIE Collaborating Centers Reports Activities, 2014

9 ) Caracappa S., Blanda V., Di Pasquale C., Torina A. (2014) Sorveglianza molecolare di infezioni da Anaplasma ovis, Babesia ovis e Theileria ovis in ovi-caprini siciliani. XXI SIPAOC National Congress. Foggia 9-12 september Marino A.M.F., Di Bella C., Giunta R., Salvaggio A., Conti R., Bauso R., Percipalle M., Schembri P. Studio sulla prevalenza della Toxoplasmosi negli allevamenti bovini della Sicilia: dati preliminari del XLVI Società Italiana di Buiatria National Congress Palermo, May 2014 d) Other (Provide website address or link to appropriate information): 4 (web site of IZSLER biobank) www. biowarehouse.net(web site of the OIE biobank network) Training courses organized by CEA: Updates and perspectives on the TSE: epidemiological, diagnostic and regulatory aspects. 5 editions: II.ZZ.SS. 24/03/2014 Napoli, 14/05/2014 Roma, 12/06/2014 Palermo, 21/10/2014 Padova, 25/11/2014 Torino. Updates on the TSE surveillance for students of Epidemiology and Veterinary Public Health (VET0227), Veterinary Medicine of Milano. 13/05/2014 IZS PLV, Torino. Improving the efficiency of epidemiological surveillance. IZS PLV 28-29/10/2014 Torino. CEROVEC: Organization of meetings and scientific events: The National Reference Centre for Veterinary and Comparative Oncology (CEROVEC) organizes yearly a scientific meeting dedicated to specific topics. In 2014 an international learning event, organized in collaboration with the Academy of Romania, was held on May in Rome. The title was Italian-Romanian Days of Comparative Oncology, Europe2014: Humans and animals allied against cancer A.M.F. Marino, M. Percipalle, C. Di Bella, P. Schembri, R.C. Lelli Esperienza della Regione Sicilia su uno studio pilota per la valutazione della prevalenza della toxoplasmosi Parte I. BENV Bollettino Epidemiologico Nazionale Veterinario july 2014, Nr OIE Collaborating Centers Reports Activities,