Depolarized GABAergic Signaling in Subicular Microcircuits Mediates Generalized Seizure in Temporal Lobe Epilepsy

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1 orrections epolrized ergic Signling in Suiculr Microcircuits Medites enerlized Seizure in Temporl Loe pilepsy Yi Wng, englin Xu, Zhengho Xu, ihong Ji, Jio Ling, Ying Wng, in hen, Xiohu Wu, eng o, Shung Wng, Yi uo, Xioming Li, Jinhong Luo, Shumin un, nd Zhong hen* *orrespondence: ( 95, 9 15; July 5, 17) fter puliction, we noticed n error in igure S5, which ws indvertently introduced during the reformtting of the finl version of the mnuscript. The western lot for K in the 3 field of hippocmpus (igure S5, right side) erroneously displyed the sme western lot s tht shown in igure S5, which reflects expression of K in the suiculum. This error hs no effect on ny of the sttistics or conclusions in the pper nd the revised figure (igure S5) hs now een corrected online. The uthors pologize for the mistke nd ny confusion this my hve cused. ª 17 lsevier nc. Reck nd pr1 re ssentil Receptor ofctors for Wnt7/Wnt7-Specific Signling in Mmmlin NS ngiogenesis nd lood-rin rrier Regultion hris ho, Philip M. Smllwood, nd Jeremy Nthns* *orrespondence: jnthns@jhmi.edu ( 95, ; ugust 3, 17) uring the production stge, minor lettering errors were introduced in igures 3 nd. These hve now een corrected oth online nd in print. The journl pologizes for the error. ª 17 lsevier nc. 95, 11 15, ugust 3, 17 11

2 Reck flex/δex1; Reck flex/δex1; Pdgf-reR/+ Pdgf-reR/+ Pdgf-reR/+ P Streptvidin ludin-5 P7 1 95, 11 15, ugust 3, 17 PLVP pr1 ; Tie-re 11.5 ludin-5 PLVP rction of vessels tht re ludin-5+ per 1 x 1 x 1 µm 1. rction of vessels tht re PLVP+ per 1 x 1 x 1 µm Tie-re S Lectin+ mcrophges in hindrin per 3 x 5 x 1 µm Tie-re S Lectin Reltive vsculr density in hindrin per 3 x 5 x 1 µm Tie-re Tie-re orrections S Lectin 1. 1 J igure 3. Reck- nd Norrin-Medited Wnt Signling Pthwys unction Redundntly to Regulte NS ngiogenesis nd ntegrity (corrected)

3 Reck flex/δex1; Reck flex/δex1; Pdgf-reR/+ Pdgf-reR/+ Pdgf-reR/+ P Streptvidin P7 ludin-5 PLVP pr1 ; Tie-re 11.5 ludin-5 PLVP rction of vessels tht re ludin-5+ per 1 x 1 x 1 µm 1. rction of vessels tht re PLVP+ per 1 x 1 x 1 µm Tie-re S Lectin+ mcrophges in hindrin per 3 x 5 x 1 µm Tie-re S Lectin Reltive vsculr density in hindrin per 3 x 5 x 1 µm Tie-re Tie-re orrections S Lectin 1. 1 J.5. zz. igure 3. Reck- nd Norrin-Medited Wnt Signling Pthwys unction Redundntly to Regulte NS ngiogenesis nd ntegrity (originl) 95, 11 15, ugust 3, 17 13

4 S Lectin+ mcrophges in M per 5 x 5 x 1 µm Reltive vsculr density in M per 5 x 5 x 1 µm 1 95, 11 15, ugust 3, 17 Reltive vsculr density in spinl cord per 35 x 5 x 1 µm Tie-re Tie-re Reck flex/δex; Tie-re Tie-re right-field (13.5) S Lectin+ mcrophges in spinl cord per 35 x 5 x 1 µm Reltive vsculr density 1 x x 1 µm S Lectin+ mcrophges 1 x x 1 µm Reck flex/δex; Tie-re orrections S Lectin S Lectin PM S Lectin PM igure. enetic vidence for Reck-pr1 nterction in NS ngiogenesis (corrected) 5 3 1

5 Reltive vsculr density in spinl cord per 35 x 5 x 1 µm Tie-re Reck flex/δex; Tie-re Tie-re right-field (13.5) S Lectin+ mcrophges in spinl cord per 35 x 5 x 1 µm. Reltive vsculr density in M per 5 x 5 x 1 µm Tie-re S Lectin+ mcrophges in M per 5 x 5 x 1 µm Reltive vsculr density 1 x x 1 µm S Lectin+ mcrophges 1 x x 1 µm Reck flex/δex; Tie-re orrections S Lectin S Lectin PM S Lectin PM igure. enetic vidence for Reck-pr1 nterction in NS ngiogenesis (originl) 95, 11 15, ugust 3, 17 15