Principles of rabies eradication
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1 WHO CC for Rabies Surveillance and Research, OIE Reference Laboratory for Rabies, Germany Principles of rabies eradication Thomas MüllerM
2 Rabies control Basic considerations Problem identification Goal Plan development Tools Principles Canine & wildlife rabies
3 Basic considerations Problem identification Canine rabies? both? Wildlife rabies? Rabies surveillance Notifiable disease Basis for any rabies control programme Collection, analysis & dissemination of data Submission & testing of indicator animals Emphasis on laboratory confirmation Reporting of human & animal rabies cases Reporting of number of PEPs
4 Basic considerations Goal Containment of disease Avoiding of further spread Elimination of disease Freedom from disease Paradigm shift one health approach
5 Basic considerations Plan development Destruction of target (reservoir) species ineffective unacceptable Mass vaccination of target species dogs - mass parenteral vaccination wildlife - oral vaccination
6 Definition A long term plan of action designed to achieve a particular goal. Criteria State Basic considerations Tool Vaccination strategy State-of-the-art of science and technology Efficiency under any condition Minimal expense maximal success Cost-effective Simple principles to follow
7 Efficiency Vaccination strategy Relation of benefits to costs Rabies cases Inefficient Efficient Money spent
8 Principles A basic generalization that is accepted as true or a basic rule that guides or influences action or decision making rules used by veterinarians to organize the elements of rabies eradication programs to create a unified vaccination strategy
9 Principles of rabies elimination in dogs mass parenteral vaccination campaigns
10 Principles Dog density estimation Classification of dogs Vaccination campaigns Dog population management Surveillance and Monitoring
11 overall dog population Methods Capture / mark / re-observe Transect counting (free roaming dogs) Priciples Dog density estimation Random house-to to-house survey (owned dogs) Dog - human ratio
12 What is a stray dog? Owned vs. unowned Principles Classification of dogs Abandoned or true ownerless Community dogs Restricted vs. free-roaming roaming Changes during day and night Feral dogs Live independent from humans
13 Organization Priciples Vaccination campaigns (1) Intersectorial collaboration Community participation Strong media support Subregional & local committees to deal with technical & logistic aspects Vaccination of all dogs (70% coverage) Regardless of age, weight or state of health, Regardless of ownership-status status Adequate coverage of puppies Identification of vaccinated dogs
14 Responsible dog ownership Annual vaccination weeks Once a y / more frequent Fixed time points Basic approaches House-to to-house visits Fixed vacc.. posts Temporary vacc.. posts (mobile teams) Supplementary measure Oral vaccination Principles Vaccination campaigns (2)
15 Removal of dogs No significant impact Worsens situation (disruption of social system) Unacceptable In certain situations the only solution (humane) Practical methods Movement restriction Habitat control Reproduction control ABC programmes neuter- and-release release Principles Dog population management
16 Principles of rabies elimination in wildlife Oral vaccination campaigns
17 Principles Vaccinated areas Timing of vaccination Bait density Mode of bait distribution Duration of vaccination Surveillance and Monitoring
18 Principles Vaccination areas large scale patchy
19 Principles Timing of vaccination (Foxes) rabies incidence 0.4 mating birth ? dispersal population turnover J F M A M J J A S O N D spring den summer autumn
20 Principles Mode of bait distribution organizational expense man power large-scale vaccination accessibility to areas cost-effectiveness control hand aerial hand and aerial distribution complement each other
21 Principles Mode of bait distribution
22 Principles Bait density Hunting bag baits per campaign fox wild boar /km 15/km /km /km / / / /01
23 Principles Bait density varying bait density varying flight line distance >20 baits Bait densities >20/km² do not increase bait uptake Very small flight line distances cannot improve the ground pattern further
24 Principles Duration of vaccination Average 6 y budget planning! cessation 2 y after last rabies case
25 Large scale > 5,000 km² Aerial & complementary hand distribution 25 baits / km²,, cross border coordination Long-term 6 y + 2 y Average 6 y ORV of wildlife Take home message Twice a y (spring /autumn) vs. once a y Stop of vaccination 2 y after last rabies case Targeted surveillance and monitoring Rabies incidence, bait-uptake, seroconversion Epidemiological analysis
26 Can rabies be eradicated? Charles Rupprecht,, Paris, 2007 Yes (a question of balance in perspective) No (if we are honest and live in the now ) Maybe (because hope springs eternal) I do not know (as ignorance is bliss, things change, and life on earth is unpredictable)
27 Thank you for your attention!
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