Scientific Program. 08:30 Phylogenomic transduction networks reveal genetic barriers for phagemediated lateral gene transfer Tal Dagan, Germany
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1 Scientific Program SUNDAY, 17 MAY :00-17:30 Welcome Kornelia Smalla, Germany 17:30-18:05 Opening Lecture Antibiotics at sub-inhibitory concentrations Fernando Baquero, Spain 18:30-20:00 Welcome Reception MONDAY, 18 MAY 2015 SESSION I: EVOLUTION OF ANTIBIOTIC RESISTANCE Chair Jan Dirk van Elsas, The Netherlands 08:30 Phylogenomic transduction networks reveal genetic barriers for phagemediated lateral gene transfer Tal Dagan, Germany 09:05 Magnitude and determinants of plasmid transfer from exogenous donor strains to complex microbial communities Barth F. Smets, Denmark 09:25 The origin of Beta-lactamase encoding genes: Are we misannotating resistance genes using sequencing data in microbial ecology? Lars Hanse, Denmark 09:45 Insights into the resistome of bacterial communities from environments shaped by exceptional antibiotic selection pressures Nachiket Marathe, Sweden 10:05 Bacterial antibiotic resistance can be induced by disinfection byproducts via mutagenesis Lu Lv, China 10:25-10:55 Coffee Break
2 MONDAY, 18 MAY 2015 SESSION II: MOBILIZING ANTIBIOTIC RESISTANCE GENES THROUGH ANTHROPOGENIC USE OF ANTIBIOTICS Chairs Steve Djordjevic, Australia Amy Pruden, United States 10:55 Xenobiotics, xenogenetics and evolution: Tracking antibiotic resistance from environment to clinic, and back again Michael Gillings, Australia 11:30 Class 1 integrons as markers of antibiotic resistance Will Gaze, United Kingdom 11:50-13:00 Lunch Break 13:00 Antibiotic use selects for strains with increased permissiveness for broadhost-range resistance plasmids within a local population Holger Heuer, Germany 13:20 Turn up the signal wipe out the noise: Gaining insights into antibiotic resistance of bacterial communities using metagenomic data Johan Bengtsson-Palme, Sweden 13:40 Dissemination of tetracycline resistance genes from a convential dairy farm via manure into field soil Dana Elhottova, Czech Republic 14:00 What's the road to resistance? 15 years of antibiotic molecules application to farm soil do not significantly increase resistance genes abundance. Joseph Nesme, Germany
3 MONDAY, 18 MAY 2015 SESSION III: MOLECULAR STUDIES REVEAL LINKS BETWEEN THE HOSPITAL AND THE ENVIRONMENT Chairs Lisa Durso, United States Will Gaze, United Kingdom 14:20 The rifamycin antibiotic resistome Gerry Wright, Canada 14:55 Co-occurrence of antibacterial biocide, metal and antibiotic resistance genes in bacterial genomes and plasmids reveals novel insights in their coselection potential Chandan Pal, Sweden 15:15 Phylogeny and comparative genomics unveil independent diversification trajectories of qnrb and genetic surroundings within Citrobacter sp. Luísa Peixe, Portugal 15:35 Exploiting unique molecular signatures created during the evolution of complex resistance regions to track imminent threats by multiple antibiotic resistant pathogens Steven Djordjevic, Australia 15:55-16:25 Coffee Break 16:25-18:30 Poster Session I
4 TUESDAY, 19 MAY 2015 SESSION IV: FATE AND EFFECTS OF ANTIBIOTICS IN THE AGRO-ECOSYSTEM Chair Kristian Koefoed Brandt, Denmark 08:30 Antibiotic resistance gene discovery in the swine intestinal microbiome Heather Allen, United States 09:05 Manure fertilization increases resident antibiotic-resistant bacteria in soil Nikolina Udikovic-Kolic, Croatia 09:25 Antibiotic resistance gene concentrations in agroecosystems following beef manure or poultry litter deposition Kimberly Cook, United States 09:45 Fate and effects of veterinary medicines in soil Jan Siemens, Germany 10:20-10:50 Coffee Break SESSION IV continued Chair Kimberly Cook, United States 10:50 Antibiotics in plant agriculture Fiona Walsh, Ireland 11:25 Antibiotic resistant bacteria from livestock husbandry are released with biogas plant digestate into the environment Stefanie P. Glaeser, Germany 11:45 Metals as co-selective agents in soil bacterial communities Kristian Koefoed Brandt, Denmark 12:05 Transport of antibiotics in wastewater irrigated soil columns and their relation with the increase of resistance genes Kathia Lueneberg, Mexico 12:25-13:25 Lunch Break
5 TUESDAY, 19 MAY 2015 SESSION IV continued Chair Pascal Simonet, France 13:25 Resistance and mobilome of fresh produce the missing link Ed Topp, Canada 14:00 Antibiotics resistance genes and resistant bacteria within an ecoagricultural system Hong Chen, China 14:20 The role of wildlife in disseminating antibiotic-resistant bacteria to and from livestock facilities Alan B.Franklin, United States 14:40 Antibiotic resistance genes in manure-amended soil and vegetables at harvest Min Qiao, China 15:00-15:30 Coffee Break 15:30-17:30 Poster session II
6 WEDNESDAY, 20 MAY 2015 SESSION V: DISSEMINATION OF ANTIBIOTICS AND ANTIBIOTIC RESISTANCE GENES THROUGH AQUATIC ECOSYSTEMS/ SEWAGE TREATMENT PLANTS Chair Kaare Nielsen, Norway 08:30 The contribution of the mobilome in the dissemination of antibiotic resistance in rivers, sediments and farm slurries Elizabeth Wellington, United Kingdom 09:05 Exploring plasmid-based dissemination of antibiotic resistance genes in environmental matrices Xavier Bellanger, France 09:25 Distribution and fate of antibiotic resistance bacteria and genes in enhanced anaerobic digestion of sewage sludge with microwave pretreatment Juan Tong, China 09:45 Transferable antibiotic resistance in rivers and estuaries Isabel Henriques, Portugal 10:20-10:50 Coffee Break 10:50 Antibiotic resistance genes in urbanizing watershed Yong-Guan Zhu, China 11:25 Multidrug-resistant human-associated bacteria from wastewater treatment plants and their receiving waters Gulf of Gdańsk, Baltic Sea (Poland). Ewa Kotlarska, Poland 11:45 Determining the minimal selective concentrations of antibacterial agents in complex aquatic bacterial communities Sara Lundström, Sweden 12:05 Antibiotic resistance genes in sewage and related water environment Tong Zhang, China
7 WEDNESDAY, 20 MAY :40-13:40 Lunch Break SESSION V continued Chair Helmut Bürgmann, Switzerland 13:40 Wastewater irrigation increases abundance of antibiotic resistance genes and potentially harmful Gammaproteobacteria in soils from Mezquital Valley, Mexico Elisabeth Grohmann, Germany 14:15 Overview of meropenem and zinc resistance in biofilms: Rotating tubular reactors and river sediments in the River Tyne Catherine Hands, United Kingdom 14:35 Antibiotic resistance in Pristine Red Sea Brine Pools Ali H A Elbehery, Egypt 14:55 Persistence of resistance genes in sewage canalization networks of metropolitan areas: relationship between antibiotic selective pressure and antibiotic resistance genes Thomas Berendonk, Germany 15:15-15:45 Coffee Break 15:45 Environmental pollution from antibiotic manufacturing creates hotspots for resistance development Joakim Larsson, Sweden 16:20 Microbial metabolic capabilities including antimicrobial biosynthesis during water infiltration revealed by metagenomic and transcriptomic analyses Jörg Drewes, Germany 16:40 Exploring the effects of anthropogenic pollution on the environmental resistome of rivers and agricultural soils in Central Mexico using microbiological and genomic approaches Pablo Vinuesa, Mexico 17:00 Temporal dynamics and source-to-tap connectivity in a surface-water fed drinking water distribution system Helmut Bürgmann, Switzerland
8 WEDNESDAY, 20 MAY :20-20:00 Free time 20:00-00:00 Conference Dinner THURSDAY, 21 MAY 2015 SESSION VI: MITIGATION STRATEGIES AND HOW TO EVALUATE THEM (Round table and Discussion groups) Chairs Mark Ibekwe, United States Heike Schmitt, The Netherlands 09:00 Mitigation strategies for environmental sources of antibiotic resistance Amy Pruden, United States 09:35 Artilysins: Highly effective antimicrobial enzymes with a low risk of resistance formation for targeted elimination of bacterial pathogens Stefan Miller, Germany 09:50 Thermophilic anaerobic digestion: an effective approach for blocking both horizontal and vertical gene transfer pathways of antibiotic resistance genes Min Yang, China 10:05 Specific in silico tools for the detection of acquired antibiotic resistance genes Gisle Vestergaard, Germany 10:20 Discussion 11:00-11:20 Coffee Break 11:20 Closing Lecture taking stock of ARGs as pollutants past, now and future Jim Tiedje, United States 12:05 Farewell and announcements Kornelia Smalla, Germany
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