Capnocytophaga canimorsus

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1 Capnocytophaga canimorsus infection caused by dog/cat-bites/scratches Michio SUZUKI C. canimorsus Capnocytophaga canimorsus 200 C. canimorsus 30 C. canimorsus Capnocytophaga canimorsus ,000 6, Pasteurella P. multocida 2, 3 Staphylococcus Laboratory of Reservoir Control of Zoonoses, Department of Veterinary Science, National Institute of Infectious Diseases (-23- Toyama, Shinjuku-ku, Tokyo)

2 Streptococcus Fusobacterium 4 Bartonella 5 C. canimorsus Capnocytophaga canimorsus C. canimorsus C. canimorsus , 8 2, 9 2 0, 9 3 Capnocytophaga Capnocytophaga Capnocytophaga C. ochracea 5 5 Capnocytophaga 6, 7 C. canimorsus C. cynodegmi 2 DF-2Dysgonic Fermenter-2 DF-2-like canimorsus cynodegmi C. canimorsus C. cynodegmi C. canimorsus Capnocytophaga 2 Capnocytophaga C. canimorsus C. cynodegmi Capnocytophaga C. ochracea C. gingivalis C. sputigena C. haemolytica C. granulosa C. canimorsus C. cynodegmi DIC

3 C. canimorsus C. canimorsus CO2 HK 5 C. canimorsus C. cynodegmi PCR 20, C. canimorsus C. cynodegmi C. canimorsus C. cynodegmi C. canimorsus C. canimorsus 200 7, 8 C. canimorsus immunocompromised host 7, 0, 7, 9, 23. Capnocytophaga C. canimorsus C. cynodegmi C. ca andor C. cy C. canimorsus C. cynodegmi C. ca andor C. cy Capnocytophaga C. ca : C. canimorsus, C. cy : C. cynodegmi

4 , , 9 7, 2 DIC 30 7, C. canimorsus 25 C. canimorsus , 23, C. canimorsus. n98 2. n70 3. n99 4. n , 23, ICU ICU 28, C. canimorsus

5 C. canimorsus No DIC DIC DIC DIC DIC DIC 3 35 immunocompromised host C. canimorsus C. canimorsus C. canimorsus 36 C. canimorsus 23, 27, 28 PCR 20, 23 PCR 20, 26 6S rrna 23 C. canimorsus C. canimorsus C. canimorsus

6 C. canimorsus ST B SXT DDDDDDDDDDDDDDDDDDDDDDDDDDDDD C. canimorsus Tel : , Fax : michios@nih.go.jp DDDDDDDDDDDDDDDDDDDDDDDDDDDDD Centers for Disease Control and PreventionCDC: Nonfatal dog bite-related injuries treated in hospital emergency departments--united States, 200. MMWR Morb. Mortal. Wkly. Rep. 26: ,., : 65-70, Holst E., Rollof J., Larsson L., et al.: Characterization and distribution of Pasteurella species recovered from infected humans. J. Clin. Microbiol. : Talan D.A., Citron D.M., Abrahamian F.M., et al.: Bacteriologic analysis of infected dog and cat bites. Emergency Medicine Animal Bite Infection Study Group. N. Engl. J. Med. 2: : 203-2, Bobo R.A. and Newton E.J.: A previously undescribed Gram-negative bacillus causing septicemia and meningitis. Am. J. Clin. Pathol. : , Gaastra W. and Lipman. L.J.A.: Capnocytophaga canimorsus. Vet. Microbiol. : 9-346, Macrea M.M., McNamee M., Martin T.J.: Acute onset of fever, chills, and lethargy in a 36-year-old woman. Chest : , Janda J.M., Graves M.H., Lindquist D., et al.: Diagnosing Capnocytophaga canimorsus infections. Emerg. Infect. Dis. : , Lion C., Escande F., Burdin J.C.: Capnocytophaga canimorsus infections in human: review of the literature and cases report. Eur. J. Epidemiol. 5: 52-5, 996. Pers C., Gahrn-Hansen B., Frederiksen W.: Capnocytophaga canimorsus septicemia in Denmark, : review of 39 cases. Clin. Infect. Dis. : 7-75, Valtonen M., Lauhio A., Carlson P., et al.: Capnocytophaga canimorsus septicemia: fifth report of a cat-associated infection and five other cases. Eur. J. Clin. Microbiol. Infect Dis. 6: , Capnocytophaga canimorsus. : 554, Leadbetter E.R., Holt S.C.,Socransky S.S.: Capnocytophaga : new genus of gram-negative gliding bacteria. I. General characteristics, taxonomic considerations and significance. Arch. Microbiol. : 9-6, p48, Buu-Hoi A.Y., Joundy S., Acar J.F.: Endocarditis caused by Capnocytophaga ochracea. J. Clin. Microbiol. 5: , Desai S.S., Harrison R.A., Murphy M.D.: Capnocytophaga ochracea causing severe sepsis and purpura fulminans in an immunocompetent patient. J. Infect. 2: e07-09, 2007.

7 8Brenner D.J., Hollis D.G., Fannning, G.R., et al.: Capnocytophaga canimorsus sp. nov.formerly CDC Group DF- 2, a cause of localized wound infection following dog bite. J. Clin. Microbiol. : , Blanche P., Bloch E., Sicard D.: Capnocytophaga canimorsus in the oral flora of dogs and cats. J. Infect. : 34, Suzuki M., Kimura M., Imaoka K., et al : Prevalence of Capnocytophaga canimorsus and Capnocytophaga cynodegmi in dogs and cats determined by using a newly established species-specific PCR. Vet. Microbiol. doi0.06 j.vetmic , Westwell A.J., Kerr K., Spencer M.B., et al.: DF-2 infection. BMJ, 6666: 6-7, ,, Capnocytophaga canimorsus. 4: 48, Moal G.L., Landron C., Grollier G., et al.: Meningitis due to Capnocytophaga canimorsus after receipt of a dog bite : case report and review of the literature. Clin. Infect. Dis. 3: e42-46, de Smet M.D., Chan C.C., Nussenblatt R.B., et al.: Capnocytophaga canimorsus as the cause of a chronic corneal infection. Am. J. Ophthalmol. 2: , Capnocytophaga canimorsus. : 9-4, : 67, ,, Capnocytophaga canimorsus., : , Capnocytophaga canimorsus. : S263, Canocytophaga canimorsus HPVB9 HPS. 8: 90, Capnocytophaga canimorsus. : 290, Capnocytophaga canimorsus. : , Capnocytophaga canimorsus 4. 4: 48, Capnocytophaga canimorsus. : S47, Morgan M. and Palmer J.: Dog bites. BMJ. 7590: Capnocytophaga canimorsus. JVM3:

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