Antibiotic Spectral Library Version 1.1 for LibraryView Software

Transcription

1 Antibiotic Spectral Library Version 1.1 for LibraryView Software

2 Antibiotic Spectral Library v1.1 for LibraryView Software An overview of the licensed mass spectral library for antibiotics compatible with LibraryView Software LibraryView Software is a fast way to analyze large batches of MS/MS data for accurate and efficient MS/MS library searching, data mining, and compound database management. We ve assembled an MS/MS spectral library compatible with LibraryView Software containing 201 antibiotic drug residue entries. This library was created using certified reference materials and can be used in LibraryView Software to perform MS/MS library searching or to create custom screening and/or quantitation methods using the integrated MRM information. Features of this MS/MS spectra library: Includes data on 201antibiotics and metabolites commonly tested for in meat and other food products. Contains 115 integrated MRM entries with up to 3 transitions per compound. Includes 201 full MS/MS spectral library entries including individual spectra acquired using three distinct collision energies (20 ev, 35 ev, 50 ev), as well as a single spectra representing the sum of all three collision energies. Contains spectra for both positive and negative ionization for compounds that ionize in both polarities. Advantages of using this MS/MS spectral library: Use the integrated MRM information to build methods without the need to re-infuse standards and optimize MRM transitions for a given compound. Easily create screening methods for an MRM triggered EPI workflow for use on QTRAP LC/MS/MS systems. Quickly set-up MRM quantitation methods for traditional MRM ratio quantitation and confirmation on a QTRAP or Triple Quad LC/MS/MS system. Set-up smaller customer libraries by simply selecting only the compounds of interest from the list in LibraryView Software. Use LibraryView Software to automatically create your custom acquisition and quantitation methods. The following is a list of the antibiotics currently in the library. This library is verified for use on AB SCIEX QTRAP LC/MS/MS systems. Please note that this library is continuously being expanded to include additional compounds. 2-Amino-5-benzoylbenzimidazole C14H11N3O Aminoflubendazole C14H10FN3O Hydroxymethyl-1-methyl-5-nitro-imidazol (HMMNI) C5H7N3O mercaptobenzimidazole C7H6N2S Nitrobenzaldehyde Semicarbazone C8H8N4O Nitrobenzaldehyde Semicarbazone-15N2-C13 (13C)(15N)2C7H8N2O N/A 4 2-NP-AHD C10H8N4O NP-AHD-13C3 (13C)3C7H8N4O N/A 4 2-NP-AMOZ C15H18N4O NP-AMOZ-D5 C15(2H)5H13N4O N/A 4 2-NP-AOZ C10H9N3O NP-AOZ-D4 C10H5(2H)4N3O N/A 4 2-quinoxalinecarboxylic acid C9H6N2O Hydroxythiabendazole C10H7N3OS phenyl-2-thiouracil C10H8N2OS Albendazole C12H15N3O2S Albendazole Sulfone C12H15N3O4S Albendazole Sulfoxide C12H15N3O3S Albendazole-2-aminosulfone C10H13N3O2S p 2

3 Amoxicillin C16H19N3O5S Ampicillin C16H19N3O4S Amprolium C14H19ClN Aprinocid C12H9ClFN Bacitracin C66H103N17O16S beta-nandrolone-d3 C18H23(2H)3O beta-trenbolone-d3 C18H19(2H)3O N/A 4 boldenone C19H26O Brilliant green C27H33N (C.I ) 4 Bromobuterol C12H18N2OBr Cambendazole C14H14N4O2S Carbadox C11H10N4O Cefazolin C14H14N8O4S Cefoperazone C25H27N9O8S Ceftiofur C19H17N5O7S Chloramphenicol C11H12Cl2N2O Chlormadinone Acetate C23H29ClO Chlortetracycline C22H23ClN2O Cimaterol C12H17N3O Cinoxacin C12H10N2O Ciprofloxacin C17H18FN3O Clenbuterol C12H18Cl2N2O Clenbuterol-D6 C12H12(2H)6N2OCl N/A 4 Clencyclohexerol C14H20N2O2Cl Clenproperol C11H16N2OCl Clindamycin C18H33ClN2O5S Clopidol C7H7Cl2NO Closantel C22H14Cl2I2N2O Cloxacillin C19H18ClN3O5S Danofloxacin C19H20FN3O Dapsone C12H12N2O2S Decoquinate C24H35NO Demeclocycline C21H21ClN2O Desethylene Ciprofloxacin C15H16FN3O Diaveridine C13H16N4O Diclofenac C14H11Cl2NO Dicloxacillin C19H17Cl2N3O5S Difloxacin C21H19F2N3O Dimetridazole C5H7N3O Dipyrone C13H16N3NaO4S Doxycycline C22H24N2O Enoxacin C15H17FN4O Enrofloxacin C19H22FN3O epi-tetracycline C22H24N2O N/A 4 Erythromycin C37H67NO Erythromycin-13C2 (13C)2C35H67NO N/A 4 Etodolac C17H21NO Febantel C20H22N4O6S p 3

4 Fenbendazole C15H13N3O2S Fenbendazole Sulfone C15H13N3O4S Fenbendazole Sulfoxide C15H13N3O3S Fenoterol C17H21NO Florfenicol C12H14Cl2FNO4S Florfenicol Amine C10H14FNO3S Flubendazole C16H12FN3O Flumequine C14H12FNO Flunixin C14H11N2O2F Gentian Violet C25H30N (C.I ) 4 Halofuginone C16H17BrClN3O Hydroxymebendazole C16H15N3O Ibuprofen C13H18O Indomethacin C19H16ClNO Ipronidazole C7H11N3O Ipronidazole-OH C7H11N3O Ipronidazole-OH-D3 C7H8(2H)3N3O N/A 4 Isochlortetracycline C22H23ClN2O Isoxsuprine C18H23NO Josamycin C42H69NO Ketoprofen C16H14O Ketotriclabendazole C13H7Cl3N2O N/A 4 Laidlomycin propionate -Ammonium C40H69O13N Lasalocid C34H54O Leucogentian violet C25H31N Leucomalachite green C23H26N Leucomalachite green-d5 C23H21(2H)5N N/A 4 Lincomycin C18H34N2O6S Lomefloxacin C17H19F2N3O Mabuterol C13H18N2OClF Maduramycin C47H80O Malachite green C23H25N Marbofloxacin C17H19FN4O Mebendazole C16H13N3O Medroxyprogesterone 17-acetate C24H34O Medroxyprogesterone acetate-d3 C24H31(2H)3O N/A 4 megestrol acetate C24H32O melengestrol acetate C25H32O Melengestrol acetate-d3 C25H29O4(2H) N/A 8 Methylcimaterol C13H19N3O Methylcimaterol-D9 C13H10(2H)9N3O N/A 4 Methylclenbuterol C13H20N2OCl N/A 5 Methylmabuterol C14H20N2OClF Methyltestosterone C20H30O Methyltestosterone-D3 C20H27(2H)3O Metoprolol C15H25NO Metronidazole C6H9N3O Metronidazole-OH C6H9N3O p 4

5 Minocycline C23H27N3O Monensin C36H62O Nafcillin C21H22N2O5S Nalidixic acid C12H12N2O Nandrolone C18H26O Naproxen C14H14O Narasin C43H72O Nicarbazin C13H10N4O Niclosamide C13H8Cl2N2O Norfloxacin C16H18FN3O Norfloxacin-D5 C16H13(2H)5FN3O N/A 4 norgestrel C21H28O Novobiocin C31H36N2O Ofloxacin C18H20FN3O Orbifloxacin C19H20F3N3O Ormetoprim C14H18N4O Oxacillin C19H19N3O5S Oxibendazole C12H15N3O Oxolinic Acid C13H11NO oxyphenbutazone C19H20N2O Oxytetracycline C22H24N2O Penicillin G C16H18N2O4S Penicillin G-D7 C16H10(2H)7N2O4S N/A 4 Penicillin V C16H18N2O5S Phenylbutazone C19H20N2O ractopamine C18H23NO Rafoxanide C19H11Cl2I2NO Ritodrine C17H21NO Ronidazole C6H8N4O Roxithromycin C41H76N2O Salbutamol C13H21NO Salbutamol-D6 C13H15(2H)6NO N/A 4 Salinomycin C42H70O Salmeterol C25H37NO Sarafloxacin C20H17F2N3O Semduramicin C45H76O Spiramycin C43H74N2O Sulfabenzamide C13H12N2O3S Sulfacetamide C8H10N2O3S Sulfachloropyridazine C10H9ClN4O2S Sulfaclozine C10H9ClN4O2S Sulfadiazine C10H10N4O2S Sulfadimethoxine C12H14N4O4S Sulfadoxine C12H14N4O4S Sulfaguanidine C7H10N4O2S Sulfamerazine C11H12N4O2S Sulfameter C11H12N4O3S Sulfamethazine C12H14N4O2S p 5

6 Sulfamethazine-D4 C12H10(2H)4N4O2S N/A 4 Sulfamethizole C9H10N4O2S Sulfamethoxazole C10H11N3O3S Sulfamethoxazole-D4 C10H7(2H)4N3O3S N/A 4 Sulfamethoxypyridazine C11H12N4O3S Sulfamonomethoxine C11H12N4O3S Sulfamoxole C11H13N3O3S Sulfanilamide C6H8N2O2S Sulfanitran C14H13N3O5S Sulfaphenazole C15H14N4O2S Sulfapyridine C11H11N3O2S Sulfaquinoxaline C14H12N4O2S Sulfasalazine C18H14N4O5S Sulfathiazole C9H9N3O2S Sulfathiazole-D4 C9H5(2H)4N3O2S N/A 4 Sulfisomidine C12H14N4O2S Sulfisoxazole C11H13N3O3S Taleranol C18H26O Taleranol-D4 C18H22(2H)4O N/A 4 Terbutaline C12H19NO Tetracycline C22H24N2O tetramisole C11H12N2S Thiabendazole C10H7N3S Thiabendazole-13C6 C4H7(13C)6N3S N/A 4 Thiamphenicol C12H15Cl2NO5S Tiamulin C28H47NO4S Tilmicosin C46H80N2O Tolfenamic acid C14H12ClNO trenbolone C18H22O Triclabendazole C14H9Cl3N2OS Triclabendazole Sulfone C14H9Cl3N2O3S Triclabendazole Sulfoxide C14H9Cl3N2O2S Trimethoprim C14H18N4O Tulobuterol C12H18ClNO Tylosin C46H77NO zeranol C18H26O Zeranol-D4 C18H22(2H)4O N/A 4 Zilpaterol C14H19N3O Product Name Part Number Antibiotic Spectral Library Version For Research Use Only. Not for use in diagnostic procedures AB SCIEX. The trademarks mentioned herein are the property of AB Sciex Pte. Ltd. or their respective owners. AB SCIEX is being used under license. Publication number: p 6