Our mission is to provide the most accurate diagnosis with the fastest turnaround times, by equipping our service with the most advanced veterinary

Transcription

1 Price List Malaysia

2 Our mission is to provide the most accurate diagnosis with the fastest turnaround times, by equipping our service with the most advanced veterinary diagnostics technology. Asia Veterinary Diagnostics works only with highly experienced boarded or double boarded veterinary pathologists, and thanks to our digitizer system experts from all over the world can discuss the cases and provide second opinions concurrently. 1

3 Welcome Since our inception in 2013, Hong Kong Veterinary Diagnostics Centre has quickly grown to be the leading provider of veterinary specialty diagnostic services in Hong Kong. More recently we have expanded our service to mainland China and Singapore and rebranded as Asia Veterinary Diagnostics. Our organization is founded on the principle of providing diagnostic services to veterinarians, by veterinarians, all of whom are boarded or double boarded veterinary pathologists, and are supported by a global network of second tier pathologists who provide second opinion and additional readings for special requests. We joined the UK NEQAS external Quality Control Histopathology and Cytology schemes, in order to provide nothing but excellence for our histopathologists, allowing us to deliver the best diagnosis for our clients. AVD is your laboratory and our team is very much looking forward to hearing your ongoing feedback, so that we can continue to provide you with everything you need as your pathology service. Emeritus Prof. Michael J. Day Director of Pathology Michael Day is Asia Veterinary Diagnostics Director of Pathology since September He is Emeritus Professor of Veterinary Pathology at the University of Bristol and Adjunct Professor of Veterinary Pathology in the School of Veterinary and Life Sciences, Murdoch University (Western Australia). Michael qualified as a veterinary surgeon from Murdoch University in After a period in small animal practice he returned to Murdoch to complete a Residency in Microbiology and Immunology, and a PhD involving collaborative research with the Royal Perth Hospital. Michael held postdoctoral positions in experimental immunology at the Universities of Bristol and Oxford and then spent a further 27 years at Bristol Veterinary School. His research focus is on companion animal immune-mediated and infectious diseases. Michael has published over 325 papers in the field of immunopathology, is author of the textbooks Clinical Immunology of the Dog and Cat (in second edition) and Veterinary Immunology: Principles and Practice (in second edition). He is co-editor of the BSAVA Manual of Canine and Feline Haematology and Transfusion Medicine (in second edition) and the texts Arthropod-Borne Infectious Diseases of the Dog and Cat (in second edition) and Canine and Feline Gastroenterology. He is a diplomate of the European College of Veterinary Pathology, and holds fellowship of the Australian Society for Microbiology, the Royal College of Pathologists and the Royal College of Veterinary Surgeons. Michael is Editor-in-Chief of the Journal of Comparative Pathology. He is a Past President of the BSAVA. Michael is a member of the Executive Board of the WSAVA and is also chairman of the WSAVA Vaccination Guidelines Group. He is a member of the Petplan Charitable Trust Scientific Committee, a member of the Board of the WSAVA AFSCAN Project and a Trustee for the Mission Rabies Project. Michael is co-founder of a university spin-out company KWS Biotest Ltd where he is Director of Pathology. He has been the recipient of the BSAVA Amoroso Award for outstanding contribution to small animal studies (1999), the BSAVA Petsavers Award (2000, 2006 & 2007), the RCVS Trust s G. Norman Hall Medal for outstanding research into animal diseases (2003), the Petplan Charitable Trust Scientific Award (2009), the Murdoch University Distinguished Alumnus Award (2015) and the FAVP Paatsama Lectureship (2016). 2 3

4 Dr. Monali Bera Head of Veterinary Support and Quality Assurance Dr Bera DVM, MS, DACVP (Anatomic Pathology) received her DVM degree from Michigan State University and her BS degree in animal physiology and neuroscience from the University of California San Diego in She works full time on-site at Asia Veterinary Diagnostics as Head of Veterinary Support and Quality Assessment/Quality Control. After completing a three year residency programme in anatomic pathology at Colorado State University, College of Veterinary Medicine and Biomedical Sciences whilst obtaining her MS degree, Dr. Bera completed a post-doctoral research fellowship at Harvard Medical School in Boston. In 2011, she obtained her board certification with the American College of Veterinary Pathologists and moved to Singapore in 2013, after accepting a position with Philip Morris International. Dr Bera is an active member of the American College of Veterinary Pathologists and the Society of Toxicologic Pathology. Dr. Chien-Che Hung Head of Microbiology and Molecular Diagnostics Dr. Hung received his Bachelor of Veterinary Medicine degree from the College of Veterinary Medicine, National Chung Hsing University, Taiwan in 2000, and a Master of Science degree in Veterinary Pathology from the same university in From 2006 to 2012, he joined the Comparative Biomedical Science program at Cornell University for his PhD, and he remained at Cornell for his postdoctoral training for the following 4 years. His research focuses on bacterial pathogenesis, specifically in salmonellosis. During , Dr. Hung received clinical bacteriology/mycology training from the Animal Health Diagnostic Center at Cornell University. Dr. Hung is a diplomate of the American College of Veterinary Microbiologists in Bacteriology and Mycology. He works full time on site for Asia Veterinary Diagnostics as Head of Microbiology and Molecular Diagnostics. 4 5

5 Our Team of Tier 1 Pathologists Dr. Rémi Froment DMV Dipl ACVP Clinical Pathologists Dr. Joe McCoy DVM MS Dipl ACVP Dr. McCoy is a graduate of the University of Florida College of Veterinary Medicine. He completed an internship in small animal medicine and a residency in pathology at Angell Memorial Animal Hospital in Boston. He was a research fellow in comparative pathology at Harvard Medical School and was director of haematology of the eastern division of Antech diagnostics prior to joining the staff of a local laboratory. Dr. McCoy is a diplomate of the American College of Veterinary Pathologists in both anatomic and clinical pathology. Dr. Ruth Houseright DVM Dipl ACVP Dr. Houseright is a 2009 graduate of Kansas State University s College of Veterinary Medicine. Following vet school, she completed a private practice internship in equine medicine and surgery before spending 2 years in mixed animal general practice. She completed a residency in clinical pathology at the University of Wisconsin-Madison, achieving ACVP diplomate status in clinical pathology in Dr. Caroline Cluzel DMV MSc Dipl ACVP Dr. Froment graduated from the École Nationale Vétérinaire de Lyon (France) in He worked with avian and exotic species before starting his residency training in Veterinary Clinical Pathology at the University of Montréal (Québec) in He became Board Certified by the American College of Veterinary Pathology (clinical pathology) in September He has worked as a contractual pathologist and locum pathologist mostly for diagnostics and toxicology pathology labs in Europe and North America until May He is currently working at the University of Montréal, Faculty of Veterinary Medicine as a clinical pathologist. Dr Froment has a strong interest in pet cancer, particularly haematological malignancies. Dr Francesco Cian DVM DipECVCP FRCPath MRCVS RCVS and European Veterinary Specialist in Clinical Pathology Francesco qualified from University of Padua (Italy) with a DVM in He spent the next 4 years in small animal practice. In 2010, he started a residency program in Clinical Pathology at the University of Cambridge, which he finished in 2013 attaining both an ECVCP and FRCPath diploma. Francesco joined the Animal Health Trust in 2013 as Head of Clinical Pathology, and from September 2015 works for Batt Laboratories (Coventry, UK). He is part of the executive board of the European College of Veterinary Clinical Pathology (ECVCP) and member of the cytology exam committee. He is author of several publications on peer-reviewed journals and of the cytology chapter of the BSAVA Manual of Veterinary Clinical Pathology (3ed). He is also Editor of the second edition of the book Veterinary Cytology: Dog, Cat, Horse and Cow: Self-Assessment Color Review Dr. Cluzel is a graduate of Nantes College of Veterinary Medicine (France). She completed an internship in equine medicine and surgery and a M.Sc. at the University of Montreal, Faculty of Veterinary Medicine (Canada) where she investigated fetal and postnatal equine articular cartilage development with magnetic resonance imaging and histology. Subsequently, she completed a residency in clinical pathology at the University of Montreal, and was certified as a Diplomate of the American College of Veterinary Pathologists in After working for one year in academia, she moved back to France and is currently clinical pathologist/ assistant director in a private veterinary diagnostic laboratory (C.A.L). Dr Cluzel enjoys various aspects of diagnostic pathology with emphasis on cytology/histology correlation, bone marrow disorders, haemostasis and infectious diseases. 6 7

6 Anatomic Pathologists Dr. Rosa De Souza Resendes DVM MSc PhD Dipl ECVP Dr. Ramesh Kovi BVs&AH MVetSc PhD Dipl ACVP Dr. Kovi was certified as a Diplomate of the American College of Veterinary Pathologists in 2012 after completing a residency in Anatomic Pathology in the College of Veterinary Medicine, University of Minnesota. He is currently working as a veterinary pathologist/assistant professor at University of Minnesota Veterinary Diagnostic Laboratory and a comparative pathologist at Comparative Pathology Shared Resource, a core laboratory for the University of Minnesota Masonic Cancer Center. His areas of interest include cancer biology, diagnostic pathology and toxicologic pathology. He is an active member of the ACVP, AAVLD, Society of Toxicologic Pathologists (STP) and the American Association for Cancer Research (AACR). Dr. Kyla A. Beguesse MS DVM Dipl ACVP Dr. Beguesse is a 2003 Sam Houston State University alumni. She received a Master s degree in Small Ruminant Nutrition and a D.V.M. degree from Tuskegee University. She completed advanced training in Anatomic Pathology as an intern at Tuskegee University School of Veterinary Medicine and resident at the University of Pennsylvania School of Veterinary Medicine. Dr. Beguesse has a strong interest in zoological, bone and cartilage pathology as well as forensics and paleopathology. She is currently the Zoological Pathology Fellow at the University of Wisconsin- Madison and Milwaukee County Zoo. Dr. Cara Pillitteri DVM CVA Dipl ACVP Dr Pillietteri is a 2006 graduate of The Ohio State University College of Veterinary Medicine and reads exotics submissions at the HKVDC. She practiced Small Animal Medicine in northern New Jersey before pursuing a residency in Veterinary Anatomic Pathology at the University of Tennessee. She was certified as a Diplomate of the American College of Veterinary Pathologists in 2015 and is also a member of the American Association of Veterinary Laboratory Diagnosticians (AAVLD), and the Davis-Thompson Foundation. Dr. Resendes graduated from Faculdadede Medicina Veterinaria, Universidade Tecnicade Lisboa in 1998, and graduated her PhD cum laude in veterinary pathology at the Departamentde d Anatomia I Sanitat Animals, Universitat Autonomade Barcelona. Dr. Rosa has been the recipient of several research grant awards for projects including Evaluation of the expression of proinflammatory cytokines by activated macrophages/kupffer cells and the activation of FasL in procine circovirus 2 (PCV2) hepatitis. Dr. Rosa has 15 peer-reviewed publications and has contributed to more than 20 conference publications for the Annual Meeting of the European Society of Veterinary Pathology and the European College of Veterinary Pathologists (ESVP/ECVP). She is currently a consultant veterinary pathologist, having previously worked for IDEXX Laboratories in the UK. Dr. Ilze Matise DVM MS PhD Dipl ACVP Dr. Matise has more than 15 years of experience in diagnostic veterinary pathology with most of this time devoted to small animal biopsies. Ilze received her veterinary degree from Latvia University of Agriculture in Ilze found her passion for veterinary pathology and received training in veterinary pathology in the US while pursuing a PhD at Iowa State University. In 2001 Ilze s professional career continued at the University of Minnesota where she held a faculty position as a diagnostic pathologist at the Minnesota Veterinary Diagnostic laboratory and as a comparative pathologist at the Masonic Cancer Center. In 2007 she was put in change of the anatomic veterinary pathology residency program at the College of Veterinary Medicine. In 2009, Ilze returned to Latvia to teach pathology and to provide a biopsy service to small animal practitioners in Latvia. She is a diplomate of the American College Veterinary Pathologists since Ilze s particular interests are dermatopathology and cancer pathology. 8 9

7 Dr. David J. Gasper DVM PhD Dipl ACVP Dr. Gasper is a veterinary anatomic pathologist specializing in the diagnostic pathology of non-domestic species including exotic companion, zoo animals, marine mammals, and laboratory animals. He received his DVM from Kansas State University, and his residency training in zoo and wildlife pathology at University of California-Davis and the San Diego Zoo. He earned a PhD in immunology of infectious diseases from the University of Wisconsin-Madison where he developed an interest in vaccine development. He is board certified in anatomic pathology by the American College of Veterinary Pathologists, and is active in many professional organizations focused on the health and welfare of exotic companion animals, zoo animals, and wildlife. Dr. Gasper is passionate about conservation efforts and strongly supports the One Health initiative. He currently shares his office with a wide variety of tarantulas and his Belgian malinois, Tango. Dr. Jennifer Dill-Okubo DVM PhD Dipl ACVP Dr. Dill-Okubo is a graduate of the University of Florida College of Veterinary Medicine. She completed a residency in Veterinary Anatomic Pathology at the University of Georgia and was certified as a Diplomate of the American College of Veterinary Pathologists in Her doctoral research involved the investigation of pathology, disease pathogenesis and molecular aspects of aquatic disease. She has extensive experience in the field of companion animal as well as exotic animal pathology. Dr. Okubo joined Asia Veterinary Diagnostics in 2017 as an anatomic pathologist with a focus on exotic and aquatic animal species. Dr. Joe McCoy DVM MS Dipl ACVP Dr. McCoy is a graduate of the University of Florida College of Veterinary Medicine. He completed an internship in small animal medicine and a residency in pathology at Angell Memorial Animal Hospital in Boston. He was a research fellow in comparative pathology at Harvard Medical School and was director of haematology of the eastern division of Antech diagnostics prior to joining the staff of a local laboratory. Dr. McCoy is a diplomate of the American College of Veterinary Pathologists in both anatomic and clinical pathology. Our Team of Second Tier Expert Pathologists Clinical Pathologists Assoc. Prof. ltamar Aroch DVM Dipl ECVIM-CA Dr. ltamar Aroch is a graduate (1990) of the Koret School of Veterinary Medicine (KSVM), Hebrew University of Jerusalem (HUJI). He has completed a rotational internship in small animal medicine (1991) and residency in small animal internal medicine (1994) at the Hebrew University Veterinary Teaching hospital (HUVTH). As a diplomate of the ECVIM-CA (Internal Medicine; 2001), Prof. Aroch is an Associate Professor at the KSVM and has been teaching veterinary clinical pathology and small animal internal medicine since 1992; has been head of the HUVTH diagnostic laboratory since 2002 and the Small Animal Internal Medicine Residency Programme Director since Prof. Aroch s research is focused on markers of diseases, infectious diseases (ehrlichiosis, spirocercosis), canine and feline diseases (heatstroke, snakebites, pancreatitis and hepatic lipidosis) and clinical pathology. He has published more than 100 papers in peer-reviewed journals, many of which are in the field of clinical pathology, and contributed two book chapters. He is a member of the advisory board of the Journal of Veterinary Clinical Pathology

8 Anatomic Pathologists Dr. Sionagh Smith (Neuropathology & Oncology) Dr. Drury Reavill DVM DABVP Dipl ACVP (Exotics Pathology) Dr. Drury Reavill DVM, DABVP (Avian and Reptile & Amphibian Practice), DACVP is a charter Diplomate of the American Board of Veterinary Practitioners and obtained avian specialty status in 1993, before recertifying in She also gained board certification from the American College of Veterinary Pathology (ACVP) in With over 19 years of experience in avian and exotic clinical practice, laboratory diagnostics and pathology, Dr Reavill is skilled in the medicine and surgery of birds, reptiles, amphibians, fish, insects, and a wide variety of exotic mammals. Graduating from Colorado State University s College of Veterinary Medicine in 1986, Dr Reavill took an associate position at the Avian Medical Center of Sacramento where she practiced for more than 8 years. During this time, she also undertook relief work for other exclusively exotic animal practices and provided clinical consultation and laboratory services to practitioners through California Avian Laboratory (a national service exclusively devoted to avian and exotic animals) as well as the California Veterinary Diagnostic Labs of West Sacramento. Dr Reavill has authored or co-authored over 30 papers, 10 book chapters, one book and a CD, each covering a wide range of exotic animal disease conditions. She is a popular presenter online through VIN and at veterinary conferences, veterinary schools, and meetings in the United States and around the world. Dr. Shannon McLeland DVM PhD Dipl ACVP (Renal Pathology) Dr. McLeland graduated from Iowa State University College of Veterinary Medicine in Following veterinary college, she completed a rotating small animal internship at Advanced Veterinary Care Center in Lawndale, California. She was accepted into a combined residency and PhD program at the College of Veterinary Medicine and Biomedical Sciences at Colorado State University where she studied feline chronic kidney disease. She is a diplomate of the American College of Veterinary Pathologists in anatomic pathology. Special interests include renal pathology with an emphasis in feline chronic kidney disease. Sionagh received her BVMS degree from the University of Glasgow in 1990, after which she spent four years in Yorkshire-based mixed practice. She returned to Scotland to join a research group at the University of Edinburgh, focusing on porcine proliferative enteropathy. This allowed her to pursue a PhD on epidemiological and pathological aspects of this disease. Sionagh began her residency training in veterinary anatomic pathology at the University of Pennsylvania in 1997 and became a diplomate of the American College of Veterinary Pathologists in 2000, after which she remained as a lecturer at the University of Pennsylvania for one more year, followed by a two-year spell as a veterinary histopathologist with Idexx Laboratories in England. Sionagh has been back in Scotland for 12 years, working as a veterinary anatomic pathologist in academia, where her main interests are companion animal surgical pathology, particularly oncological and neuromuscular pathology, and contributing to the training of future veterinary pathologists. She is a member of the British Society of Veterinary Pathology, a Senior Fellow of the Higher Education Academy and a Royal College of Veterinary Surgeons Specialist in Veterinary Pathology. Dr. Ted van den Ingh DVM PhD Dipl ECVP (Liver Pathology) Dr van den Ingh graduated in 1969 from the Faculty of Veterinary Science, Utrecht University. After graduation he completed an internship in veterinary pathology and finished his PhD on pathology and pathogenesis of experimental trypanosomiasis in rabbits in After one year at the Department of Veterinary Pathology, Faculty of Veterinary Medicine, Bern University, he became Head of the Diagnostic Services for Domestic Animals, Faculty of Veterinary Science, Utrecht, University in 1978 and remained so untill his retirement. In this function he was also responsible for the education of the residents in veterinary pathology. He is board certified by the European College of Veterinary Pathologist. Dr van den Ingh has published over 250 pear-reviewed papers on a broad range of subjects in diagnostic and experimental veterinary pathology but particularly in his special area of interest: liver diseases in horses and small domestic animals. He was member of the WSAVA Liver Standardization Group and main author on the chapters on histology in the Standards for Clinical and Histological Diagnosis of Canine and Feline Liver Diseases and their recent updates in

9 Dr. Joanne Mansell (Dermatopathology) Joanne received her DVM from the University of Florida in She completed a residency in Anatomic Pathology at the University of Georgia and became board certified by the American College of Veterinary Pathology in She joined the faculty at the University of Georgia in 1993 as Assistant Professor. Dr. Mansell joined the Department of Veterinary Pathobiology in the CVM at Texas A&M in 2000 as Clinical Associate Professor and Chief of Surgical Pathology, became Professor in the department, and is now Emeritus Professor. She specializes in dermatopathology and ran a specialty dermatopathology biopsy service open to clients around the USA. Dr. Mansell s interests have included cutaneous paraneoplastic conditions, cutaneous microbiome in domestic animals, and gastrointestinal pathology. She has authored and co-authored over 60 peer reviewed publications and 6 book chapters. She is past president of the International Society of Veterinary Dermatopathology, and has been on the scientific committee of 14 international dermatopathology and pathology meetings. Dr. Mansell is an editorial advisor for the Journal of Comparative Pathology, and provides peer-review of manuscripts for 5 other scientific journals

10 Price List Contents *Please note all prices exclude general sales tax (GST). Immunology Histopathology - Extended Coombs test - Vaccicheck test for core vaccine protection - Leptospirosis IgM test - Allergy testing and provision of immunotherapy (please refer to our HESKA brochure) - AChR Antibody test 21 - Routine small/large specimen - Skin biopsy specimen - Endoscopic biopsy specimen - Additional services 18 Serum Biochemistry Profiles Cytology Microbiology - Routine - Cytology of washes - Fluid analysis Immunohistochemistry (IHC) and Immunocytochemistry (ICC) - IHC/ICC lymphoma typing - Mast cell tumour prognostic panel - PCR including c-kit mutation PCR Haematology - Complete blood count with morphology - Blood smear interpretation - Blood parasites screen - Reticulocyte count with CBC - Anaemia Panel Canine - Anaemia Panel Feline - CSF analysis - Additional services Bone Marrow Study Genomic Assay General - Urine - Faeces - Bacterial Stains Molecular Diagnostics Single Tests Panels - Virus - Canine - Parasite - Feline - Bacteria - Fungi Additional Tests Sample Submission Contact Details Submission Forms Specialist Case Review

11 Histopathology 2-6 working days Cytology 1-2 working days Requirement* Fee (SG$ ex.gst) Requirement Fee (SG$ ex.gst) Small biopsy specimen (Full margin evaluation included) Single small specimen 90 <8cm maximum Second small specimen from the same animal (different site) 45 dimension Each additional small specimen from the same site 20 Large biopsy specimen (Full margin evaluation included) Single large specimen 195 >8cm dimension Second large specimen from the same animal (different site) 95 Skin biopsy specimen Skin punch biopsy samples Up to 3 from the same animal Each additional skin punch from the same animal 20 Endoscopic biopsy specimens Endoscopic biopsy samples Up to 20 from one site Endoscopic biopsy samples from a different site in the same animal 20 Liver-plus panel Standard histology plus panel of Fouchet s, Perl s Prussian blue, reticulin and rubeanic acid stains Additional services Panel of special stains for infectious disease screening (Gram, periodic acid-schiff and Ziehl Neelsen) Small liver biopsy sample (<8cm) Other individual special stains 25 Decalcification fee (for tissues containing bone; applied in addition to histology charge) FISH (fluorescence in-situ hybridization) testing - first tissue (turnaround time 7-12 days- call laboratory for availability) Recommended after histopathology FISH (fluorescence in-situ hybridization) testing - additional tissues 100 Second opinion on case from another laboratory Internal second opinion by second-tier specialist pathologist *Tissue in Formalin % on test required Routine cytology Cytology of single site or lesion Up to 4 slides, air dried 65 Each additional slide from the same site 1 slide, air dried 10 Cytology from a different site in the same animal Up to 4 slides, air dried 50 Cytology of washes Cytology of one wash sample 0.5 ml wash (e.g. BAL, prostatic, tracheal, cyst content, nasal, urine) in EDTA +/- air 65 Cytology of additional wash sample from the same animal dried smear 60 Fluid analysis Cytology of one synovial, pleural, abdominal or pericardial fluid 0.5 ml fluid in (including specific gravity, protein concentration, RBC & WBC counts) EDTA +/- air 80 Each additional fluid sample from the same animal dried smear 55 CSF analysis Cytology of CSF including microprotein, RBC count and WBC count 0.5 ml fluid in EDTA +/- air 80 dried smear Additional services Consultation on cytology cases not submitted to AVD 60 Clinical pathology consultation/interpretation of laboratory data performed in clinic or elsewhere 60 IHC and ICC working days lmmunohistochemistry (IHC) and immunocytochemistry (ICC) IHC lymphoma typing, including WHO classification Recommended after 220 ICC lymphoma typing, B and T lymphocyte markers histopathology or 210 Each individual ICC/IHC marker - initial cytology. ICC will be 150 Each individual ICC/IHC marker - additional dependent on having 90 Mast cell tumour prognostic panel additional unstained 2 c-kit expression (CD117) for TKI chemotherapy smears. IHC can be performed 190 PCR including c-kit mutation PCR using the same sample as submitted for initial histopathology Please call laboratory for prices 18 19

12 Genomic Assay 5-7 working days Immunology 1-2 working days Requirement Fee (SG$ ex.gst) Requirement Fee (SG$ ex.gst) Genomic Assay Performed on the same sample Customised Innogenics Gene Signature Assay for submitted for histopathology or characterization of cancer-related gene expression for cytological samples, requiring 4 by tumours additional unstained slides Bone Marrow Study 360 Immunology Extended Coombs test (4 antibodies Canine, 3 Feline) 2 ml EDTA blood * 150 Vaccicheck test - canine (CDV, CAV, CPV2) 2 ml clotted blood 25 Vaccicheck test - feline (FPV, FHV, FCV) or 1 ml serum 25 Leptospirosis lgm test (for diagnosis of acute 1 ml whole blood or serum infection [recommend concurrent PCR testing]) or plasma 55 Acetylcholine receptor antibody 2 ml clotted blood or 1 ml serum 270 Bone Marrow Study 4 slides (air dried) +/- aspirate in Serum Biochemistry Profiles 1-2 working days Bone marrow aspirate cytology (turnaround time 3 working days) EDTA and peripheral blood smear (air dried) +/- 1 ml blood in EDTA and recent CBC data 110 Serum Biochemistry Profiles Combined evaluation of bone marrow aspirate and core biopsy samples (turnaround time 5 working days) Core biopsy and 4 slides (air dried) +/- aspirate in EDT A and peripheral blood smear (air dried) +/- 1 ml blood in EDTA and recent CBC data 140 Comprehensive diagnostic profile: 14 parameters include albumin (ALB), alkaline phosphatase (ALP), alanine transaminase (ALT), amylase (AMY), urea (BUN), calcium (Ca), creatinine 0.5 ml serum in plain tube, separated from blood clot 165 (CREA), globulin (GLOB), glucose (GLU), potassium within 30 minutes of collection Haematology 1-2 working days (K), sodium (Na), phosphate (PHOS), total bilirubin (TBIL), total protein (TP) Haematology CBC 1 ml EDTA blood 35 Blood smear interpretation by pathologist 2 slides (air dried) 90 CBC with blood smear interpretation by pathologist + 1 ml EDTA blood 110 Blood parasite screen (air dried smear from the ear tip) 2 slides, air dried 100 Kidney profile plus: 10 parameters include albumin (ALB), urea (BUN), calcium (Ca), chloride (Cl), creatinine (CREA), glucose (GLU), potassium (K), sodium (Na), phosphate (PHOS), bicarbonate (tco₂) 0.5 ml serum in plain tube, separated from blood clot within 30 minutes of collection 135 Reticulocyte count (including CBC) 1 ml EDTA blood 35 Canine anaemia panel (Full CBC, reticulocyte count, blood smear reviewed by pathologist, Babesia spp. and Ehrlichia spp. q-pcr, Coombs test) Feline anaemia panel (Full CBC, reticulocyte count, blood smear reviewed by pathologist, Mycoplasma haemofelis, Candidatus Mycoplasma haemominutum, Candidatus Mycoplasma turicensis q-pcr, FeLV PCR, 2 ml EDTA sample and smear (In severely anemic patients, please send 3 ml for adequate cellularity of the sample) Avian/Reptile profile: albumin (ALB), aspartate aminotransferase (AST), bile acids (BA), calcium (Ca), creatinine kinase (CK), globulin (GLOB), glucose (GLU), potassium (K), sodium (Na), phosphates (PHOS), total protein (TP), uric acid (UA) 300 μl whole blood in heparin. If glucose required 300 μl serum in plain tube instead 135 FIV PCR, Coombs test) 20 *in case of severely anemic patient, please send 3 ml for appropriate cellularity of the sample 21

13 Microbiology Molecular Diagnostics 2-4 working days Requirement Fee (SG$ ex.gst) Requirement* Fee (SG$ ex.gst) Microbiology Swab with Amies transport Aerobic culture and sensitivity test medium, fluid in sterile (Turnaround time 2-4 working days) container. Specify source 30 To be inoculated into anaerobic transport media (ATM) vials Anaerobic culture and sensitivity test and kept at room temperature (Turnaround time 2-6 working days) C. Samples should be 40 submitted to the lab within 24 hours Urine culture and sensitivity test (Turnaround time 2-4 working days) 1 ml urine in sterile container 25 Faecal culture and sensitivity test (Turnaround time 2-6 working days) 5g stool in sterile container ml blood in blood culture Blood culture bottle. Contact laboratory to be (Turnaround time 7-10 days) sent blood culture bottle 60 Fungal culture Tissue, hair, skin scraping, (Turnaround time up to 21 days) body fluid in sterile container 30 Gram stain Swab with Amies transport 15 (Turnaround time 2 days) medium, fluid in sterile Ziehl-Neelsen stain (Acid Fast Stain) container. Specify source 15 (Turnaround time 2 days) Faecal occult blood 5g stool in sterile container 15 Urinalysis (dip stick and sediment) 15 5 ml urine in sterile container Urinalysis + urine culture 35 Molecular Diagnostics Canine tick-borne infectious disease profile (Babesia genus, Ehrlichia genus) Canine gastrointestinal panel (Giardia intestinalis, Cryptosporidium spp., Salmonella spp., Clostridium perfringens, canine coronavirus, canine parvovirus 2) Canine respiratory tract infection panel (Fungus kingdom, Streptococcus spp., Mycoplasma spp., Bordetella bronchiseptica, canine influenza [H3N8] [H3N2], canine distemper virus, canine adenovirus 2, canine parainfluenza virus, canine respiratory coronavirus) Feline gastrointestinal panel (Giardia intestinalis, Cryptosporidium spp., Tritrichomonas foetus, Toxoplasma gondii, Salmonella spp., Clostridium perfringens, feline coronavirus [FeCoV], feline panleukopenia virus) Feline respiratory tract infection panel (Fungus kingdom, Streptococcus spp., Mycoplasma spp., Chlamydia spp., feline calicivirus, feline herpesvirus-1, Bordetella bronchiseptica) Skin infection panel (Fungus kingdom [fungus, yeast and mould], bacteria domain, Staphylococcus aureus with methicillin resistance gene MecA [MRSA]) Gastrointestinal parasite profile feline (Tritrichomonas foetus, Giardia intestinalis, Cryptosporidium spp.) Gastrointestinal parasite profile canine (Giardia intestinalis, Cryptosporidium spp.) Canine neurology panel (Borrelia spp., Canine distemper virus [CDV], Cryptococcus spp., Neospora spp., Toxoplasma gondii, Bacterial 16S ribosome PCR + Cytology) Feline neurology panel (Cryptococcus spp., Feline Coronavirus [FCoV], FeLV, FIV, and Toxoplasma gondii PCR, Bacterial 16S ribosome PCR + Cytology) 1 ml EDTA blood 100 5g stool in sterile container ml transtracheal wash (TTW) or bronchiolar-alveolar lavage (BAL) 140 fluid in sterile plain tube 5g stool in sterile container ml transtracheal wash (TTW) or bronchiolar-alveolar lavage 140 (BAL) fluid in sterile plain tube, oropharyngeal swab Deep lesion: fresh skin biopsies in plain tube with 0.5 ml sterile saline to keep moist (not wet), swab from deep in tissue placed 205 in aerobic transport media. Superficial lesion: 0.5-3mg hair and skin scraping, wound swab laced in aerobic transport media 90 5g stool in sterile container 230 CSF 1 ml volume in EDTA *Samples for molecular diagnostics are best kept as cool as possible. They should be kept refrigerated or on ice, but not frozen. 23

14 Molecular Diagnostics 2-4 working days Molecular Diagnostics 2-4 working days Requirement Fee (SG$ ex.gst) Requirement Fee (SG$ ex.gst) Virus Feline coronavirus 1 ml fluid, blood in EDTA/ tissue in sterile container Feline calicivirus 1 ml transtracheal wash (TTW) or bronchiolar-alveolar lavage (BAL) Feline herpesvirus type 1 fluid in sterile plain tube or dry oropharyngeal swab Feline panleukopenia virus (Feline parvovirus) 5g stool sample, tongue swab, tissues including gut or lymphoid in 80 sterile container Feline leukaemia virus (FeLV) 0.5 ml EDTA blood or bone marrow aspirate collected into EDTA Feline immunodeficiency virus (FIV) 0.5 ml EDTA blood Canine parvovirus 2 5g stool sample, tongue swab, tissues including gut or lymphoid in sterile container Canine distemper virus 1 ml EDTA blood or serum, CSF or urine. Transtracheal wash (TTW) or BAL fluid. Conjunctival, nasal or genital swab. Tissue samples. Canine Parainfluenza Virus 1 ml transtracheal wash (TTW) or bronchiolar-alveolar lavage (BAL) fluid in sterile plain tube Parasite Cryptosporidium spp. 5g stool in sterile container Babesia canis/gibsoni 1 ml EDTA blood Ehrlichia spp. Anaplasma spp. (for detecting Anaplasma platys) 1 ml EDTA whole blood Giardia intestinalis 5g stool in sterile container Tritrichomonas foetus 80 Anaplasma phagocytophilium 1 ml EDTA whole blood Bacteria Swab placed in aerobic transport media or 1 ml fluid, blood in EDTA. Deep lesion: fresh skin biopsies in plain tube with 0.5 ml sterile Staphylococcus aureus with methicillin saline to keep moist (not wet), swab from resistance gene MecA (MRSA) deep in tissue placed in aerobic transport media. Superficial lesion: mg hair and skin scraping, wound swab placed in aerobic transport media. Bordetella spp. 1 ml transtracheal wash (TTW) or bronchiolar-alveolar lavage (BAL) fluid in sterile plain tube, 1.0 ml EDTA. Throat swab Bartonella spp. 1 ml EDTA whole blood Clostridium perfringens 80 5g stool in sterile container Salmonella spp. Leptospira spp. 1 ml blood in EDTA, 5 ml urine in sterile container Mycoplasma spp. (canis and cynos) Throat swab, ocular swab, transtracheal wash Mycoplasma felis (TTW) or BAL, CSF, synovial or pleural fluid Mycoplasma haemocanis 1 ml EDTA whole blood Candidatus Mycoplasma haematoparvum Feline Haemotropic Mycoplasma (Mycoplasma haemofelis, Candidatus Mycoplasma haemominutum, Candidatus 1 ml EDTA whole blood Mycoplasma turicensis) Bacteria domain Deep lesion: fresh skin biopsies in plain tube with 0.5 ml sterile saline to keep moist (not wet), swab from deep in tissue placed in aerobic transport media. Superficial lesion: mg hair and skin scraping, wound swab placed in aerobic transport media. Chlamydia spp. Dry or VTM conjunctival swab Fungi Encephalitozoon spp. 1 ml EDTA whole blood *Samples for molecular diagnostics are best kept as cool as possible. They should be kept refrigerated or on ice, but not frozen

15 Additional Tests 1-2 working days Additional Tests 1-2 working days Requirement Fee (SG$ ex.gst) Requirement Fee (SG$ ex.gst) Thyroid Total T3 Free T4 T4 antibodies Total T4 T4 canine pre/post T4/TSH TSH Thyroid panel (Free T4, TT4, TSH) Canine TRH stimulation Feline TRH stimulation 2 ml clotted blood or 1 ml Serum Serum. Collect basal blood sample. Inject TRH I/V slowly over one minute (1.5 kg- 100μg TRH, 5-30 kg- 200μg TRH, > 30 kg- 300μg TRH). Take second blood sample 4-6 hours later for post T4 concentration Serum. Collect basal blood sample. Inject 0.1 mg TRH I/V slowly over one minute. Take second blood sample 4-6 hours later for post T4 concentration Therapeutic drug monitoring Digoxin 2 ml clotted blood or 1 ml serum Phenobarbitone 50 Phenobarbitone x 2 (pre/post dosing) Peak and trough specimens 90 Phenytoin ml clotted blood or 1 ml serum Potassium bromide 90 Miscellaneous blood tests B₁₂ and Folate 2 ml clotted blood or 1 ml serum Emergency Submission Fee: STAT submission 1.5x listed price Cancellation Fee: Cancellation after sample pick up and registration 100 HKD 27

16 Submission Forms Molecular Diagnostics Submission Form Telephone: asiaveterinarydiagnostics.com Clinic Information Patient Information Name of submitting veterinarian: Owner s name: Sex M/F: Microbiology Submission Form Telephone: Clinic/Address Label: Neutered Y/N: admin@asiaveterinarydiagnostics.com Clinic Information asiaveterinarydiagnostics.com Patient Information Patient s name: Date Sample Collected: Name of submitting veterinarian: Owner s name: Sex M/F: Species: Time Sample Collected: Clinic/Address Label: Neutered Y/N: Breed: Patient s name: Date Sample Collected: Age: Species: Breed: Age: Time Sample Collected: Real Time PCR Molecular Diagnostics (Do not freeze samples, store refrigerated!) Single Panel Virus Bacteria Canine tick-borne infectious disease profile (Babesia & Ehrlichia) Feline coronavirus Staphylococcus aureus with Canine gastrointestinal panel (Giardia intestinalis, Cryptosporidium Feline calicivirus methicillin resistance gene spp., Tritrichomonas foetus, Salmonella spp., Clostridium perfringens, General Faeces Feline herpesvirus type 1 MecA (MRSA) canine coronavirus, canine parvovirus 2) Indicate specimen type and anatomic location: Faecal culture and sensitivity Faecal occult blood Feline panleukopenia virus (Feline parvovirus) Bordetella spp. Bartonella spp. Feline gastrointestinal panel (Giardia intestinalis, Cryptosporidium spp., Toxoplasma gondii, Salmonella spp., Clostridium perfringens, feline Bacterial Stains Feline leukaemia virus FeLV Chlamydia spp. coronavirus [FeCoV], feline panleukopenia virus) Routine aerobic culture and sensitivity Anaerobic culture Gram stain Ziehl-Neelsen stain (Acid Fast Stain) Feline immunodeficiency (FIV) Canine parvovirus 2 Clostridium perfringens Salmonella spp. Skin infection panel (Fungus kingdom [fungus, yeast and mould], bacteria domain, Staphylococcus aureus with methicillin resistance Fungal culture Additional Information/History Canine distemper virus Leptospira spp. gene MecA [MRSA]) Blood culture aerobic and anaerobic Urine Test Required Sample Pertinent history and specimen information: Parasite Cryptosporidium spp. Babesia canis/gibsoni Mycoplasma spp. (canis & cynos) Feline haemotropic Mycoplasma (three species) Canine neurology panel (Borrelia spp., Canine distemper virus [CDV], Cryptococcus spp., Neospora spp., Toxoplasma gondii, Bacterial 16S ribosome PCR + Cytology) Urine culture sensitivity test Urinalysis + urine culture Urinalysis (dip stick and sediment) Cystocentesis Free catch Catheterization Ehrlichia spp. Anaplasma spp Giardia intestinalis Mycoplasma haemocanis Candidatus Mycoplasma haematoparvum Feline neurology panel (Cryptococcus spp., FCoV, FeLV, FIV, Toxoplasma gondii PCR, Bacterial 16S ribosome PCR + Cytology) Differential diagnosis: Tritrichomonas foetus Bacteria domain Canine Gastrointestinal parasite profile (Tritrichomonas foetus, Anaplasma phagocytophilium Fungi Encephalitozoon spp. Giardia intestinalis, Cryptosporidium spp.) Additional Information/History Pertinent history and specimen information: Treatment and response: Differential diagnosis: Treatment and response: 28 29

17 Histopathology and Cytology Submission Form Telephone: Name of submitting veterinarian: Clinic lnformation asiaveterinarydiagnostics.com Patient Information Owner s name: Sex M/F: Specialist Case Review Clinic/Address Label: Patient s name: Neutered Y/N: Date Sample Collected: Additional Information/History Species: Breed: Age: Description Time Sample Collected: A second tier clinical pathologist and/or internist will review the clinical history and all of our laboratory data (from different disciplines) related to your case, and provide an overall case interpretation with recommendations for any further diagnostics or broad management options. Pertinent history and specimen information: Site of organ, location of lesion, number of biopsies etc. The case review comprises a concise (up to 1 page) written summary from our specialist and is over and above any interpretations given for single tests. (SG$90) Differential diagnosis: Indicate site of sample collection: Sample Submission Treatment and response: Dorsal Cytology Number of slides: Cytology (up to 4 air dried or methanol-fixed smears) Fluid Analysis Cytology (synovial, pleural, abdominal, pericardial) (>0.5ml fluid in EDTA +/- air dried smear) Spinal Fluid Analysis Cytology (EDTA/Plain) Advanced booking for collection Bone Marrow (up to 4 air dried smears +/- aspirate in EDTA} (air dried blood smear or 1 ml EDTA or recent CBC result) Cytology Washes (>0.5ml fluid in EDTA +/- air dried smear) (BAL, prostatic wash, tracheal wash, cystic mass, nasal flush, urine) (up to 4 air dried or methanol-fixed slides) Ventral Histology (fixed in formalin) Type of biopsy Number of specimens: Endoscopic Excisional (Surgical margins identified Y / N ) Incisional Tru-cut Bone marrow core biopsy Decalcification Bone marrow core biopsy with aspirates and CBC data (air dried blood smear or 1 ml EDTA or recent CBC result) Submission forms for our different laboratory disciplines are provided to you as tear-off pads for your convenience and are available to download from our website asiaveterinarydiagnostics.com We will also provide you with plastic sample submission bags and formalin-filled sample pots for biopsy submissions. Advice on the correct method for sample packaging can be found on our website. We run a full courier collection service direct to your practice and our couriers will deliver forms and submission materials as requested

18 Contact Us / Book a Pick-up Address 466 Serangoon Road #03-01 Singapore Opening Hours 09:30-18:30 Mondays to Saturdays Closed on Sunday and Public Holidays Call before 12pm for sample to be collected before 2pm Call before 3pm for sample to be collected before 5pm Contact Telephone: info@asiaveterinarydiagnostics.com Web: asiaveterinarydiagnostics.com 32

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