OIE Collaborating Centres Reports Activities

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1 OIE Collaborating Centres Reports Activities Activities in 2016 This report has been submitted : :33:58 Title of collaborating centre: Parasites zoonotiques transmis par les aliments Europe Address of Collaborating Centre: 14, rue Pierre et Marie Curie, Maisons-Alfort cedex FRANCE Tel.: +33 (0) Fax: +33 (0) address: isabelle.vallee@anses.fr Website: Name of Director of Institute (Responsible Official): Pascal Boireau Name (including Title and Position) of Head of the Collaborating Centre (formally OIE Contact Point): Dr Isabelle Vallee Resaerch scientist, Head of the French National Reference Laboratory for Foodborne Parasites Deputy head to the Research Unit "Parasitc Mlecular Biology and Immunology" Name of writer: Isabelle Vallee OIE Collaborating Centres Reports Activities,

2 ToR: To provide services to the OIE, in particular within the region, in the designated specialty, in support of the implementation of OIE policies and, where required, seek for collaboration with OIE Reference Laboratories ToR: To identify and maintain existing expertise, in particular within its region 1. Activities as a centre of research, expertise, standardisation and dissemination of techniques within the remit of the mandate given by the OIE Epidemiology, surveillance, risk assessment, modelling Surveillance activities on parasites circulation within livestock Trichinella spp, Toxoplasma gondii, Cryptosporidium spp. Training, capacity building Training for direct detection of Trichinella larvae in meat Official method for trichinella detection in meat, quality assurance, proficiency testing Zoonoses - development of serological tests for trichinella detection in pigs; Research programs for improvement of foodborne parasite detection or innovative treatments - improvement of Toxoplasma gondii detection in livestock and identification of contamination sources; -development of new therapeutic approaches to control Cryptosporidium and Giardia infection in animals. Wildlife Surveillance activities on foodborne parasites in wildlife Trichinella spp, Toxoplasma gondii, Alaria alata circulation in wild boars, foxes, wolves. Diagnosis, biotechnology and laboratory Diagnosis of Foodborne parasites Identification of foodborne parasites by direct methods, serology or molecular typing. Vaccines 2 OIE Collaborating Centres Reports Activities, 2016

3 Development of vaccines to protect target animal species Research programs to develop vaccines against Trichinella in pigs, and Toxoplasma in cats Food safety Reference and Expertise activities on foodborne zoonotic parasites Develpment of new tools to control parasites, standardisation and normalisation of protocols, trianings, ring trial organisation, proficiency samples ToR : To propose or develop methods and procedures that facilitate harmonisation of international standards and guidelines applicable to the designated specialty 2. Proposal or development of any procedure that will facilitate harmonisation of international regulations applicable to the surveillance and control of animal diseases, food safety or animal welfare Proposal title /Content Applicable area Development of serological tools for detection of trichinella in pigs identification of antigenic targets to develop serological tests Surveillance and control of animal diseases Food safety Animal welfare ToR: To establish and maintain a network with other OIE Collaborating Centres designated for the same specialty, and should the need arise, with Collaborating Centres in other disciplines ToR: To carry out and/or coordinate scientific and technical studies in collaboration with other centres, laboratories or organisations 3. Did your Collaborating Centre maintain a network with other OIE Collaborating Centres (CC), Reference Laboratories (RL), or organisations designated for the same specialty, to coordinate scientific and technical studies? Yes Name of OIE CC/RL/other organisation(s) Location Region of networking Centre Purpose OIE Collaborating Centre for Foodborne Zoonotic Parasites Saskatoon, Canada Africa Americas Asia and Pacific Europe Middle East Research collaboration, reference and expertise activities. OIE Collaborating Centres Reports Activities,

4 OIE Collaborating Centre for Foodborne Zoonotic Parasites Changchun, RP China Africa Americas Asia and Pacific Europe Middle East Research collaboration, reference and expertise activities. 4. Did your Collaborating Centre maintain a network with other OIE Collaborating Centres, Reference laboratories, or organisations in other disciplines, to coordinate scientific and technical studies? ToR: To place expert consultants at the disposal of the OIE. 5. Did your Collaborating Centre place expert consultants at the disposal of the OIE? ToR: To provide, within the designated specialty, scientific and technical training to personnel from OIE Member Countries 6. Did your Collaborating Centre provide scientific and technical training, within the remit of the mandate given by the OIE, to personnel from OIE Member Countries? Yes a) Technical visits: 0 b) Seminars: 0 c) Hands-on training courses: 0 d) Internships (>1 month): 1 Type of technical training provided (a, b, c or d) Content Country of origin of the expert(s) provided with training. participants from the corresponding country d detection and molecular typing of cryptosporidium isolate from bovine Algeria 1 ToR: To organise and participate in scientific meetings and other activities on behalf of the OIE 7. Did your Collaborating Centre organise or participate in the organisation of scientific meetings on behalf of the OIE? 4 OIE Collaborating Centres Reports Activities, 2016

5 ToR: To collect, process, analyse, publish and disseminate data and information relevant to the designated specialty 8. Publication and dissemination of any information within the remit of the mandate given by the OIE that may be useful to Member Countries of the OIE a) Articles published in peer-reviewed journals: 6 Bai, X., Wang, X.L., Tang, B., Shi, H.N., Boireau, P., Rosenthal, B., Wu, X.P., Liu, M.Y., Liu, X.L., The roles of supernatant of macrophage treated by excretory-secretory products from muscle larvae of Trichinella spiralis on the differentiation of C2C12 myoblasts. Vet Parasitol 231, Ding, J., Bai, X., Wang, X.L., Wang, Y.F., Shi, H.N., Rosenthal, B., Boireau, P., Wu, X.P., Liu, M.Y., Liu, X.L., Developmental profile of select immune cells in mice infected with Trichinella spiralis during the intestinal phase. Vet Parasitol 231, Djokic, V., Blaga, R., Aubert, D., Durand, B., Perret, C., Geers, R., Ducry, T., Vallee, I., Djurkovic Djakovic, O., Mzabi, A., Villena, I., Boireau, P., 2016a. Toxoplasma gondii infection in pork produced in France. Parasitology 143, Djokic, V., Fablet, C., Blaga, R., Rose, N., Perret, C., Djurkovic-Djakovic, O., Boireau, P., Durand, B., 2016b. Factors associated with Toxoplasma gondii infection in confined farrow-to-finish pig herds in western France: an exploratory study in 60 herds. Parasites and vectors 9, 466. Ruetsch, C., Delaunay, P., Armengaud, A., Peloux-Petiot, F., Dupouy-Camet, J., Vallee, I., Polack, B., Boireau, P., Marty, P., Inadequate labeling of pork sausages prepared in Corsica causing a trichinellosis outbreak in France. Parasite 23, 27. Yang, Y., Vallee, I., Lacour, S.A., Boireau, P., Cheng, S.P., Liu, M.Y., Identification and characterization of immunodominant linear epitopes on the antigenic region of a serine protease in newborn Trichinella larvae. J Helminthol 90, b) International conferences: 0 c) National conferences: 4 D Leroux. Immune response induced by the Mic1-3 Knockout Toxoplasma gondii vaccine strain in the parasite definitive host : the cat mars 2016 : 10èmes journées du réseau français "Immunologie des Animaux Domestiques" IAD 2016, ISPAIA Zoopôle, Ploufragan, France. P Boireau. Rôle des DNAseII de Trichinella dans l'échappement à la réponse immunitaire mars 2016 : 6ème journées d'études du pôle Santé & Société de l Université Paris-Est «Agents infectieux et vaccins chez l'homme et l'animal», ENVA, Maisons-Alfort, France. Isabelle Vallee. Développement d'un vaccin recombinant contre la trichinellose porcine mars 2016 : 6ème journées d'études du pôle Santé & Société de l Université Paris-Est «Agents infectieux et vaccins chez l'homme et l'animal», ENVA, Maisons-Alfort, France. G. Karadjian, A. Heckmann, C. Calvet, P. Boireau, S. Bellier & I. Vallée. New proteomic and molecular tools for the identification and the functional characterization of target proteins for therapeutic, vaccine and diagnostics Mars 2016, Colloque Lunepar (Nematode national network)., Tours, France. d) Other (Provide website address or link to appropriate information): 0 OIE Collaborating Centres Reports Activities,

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