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1 3 収集 翻訳文献本事業で収集し 要旨の翻訳を行った160 文献の一覧を表 2に示した 表 2 収集文献一覧 番号表題著者名 ( 発行年 ) 掲載誌 0001 A case-case comparison of Campylobacter coli and Campylobacter jejuni infection: a tool for generating hypotheses (C. coli 及び C. jejuni 感染症の症例 - 症例比較 : 仮説を立てるための手法 ) A case-control study of risk factors for sporadic campylobacter infections in Denmark( デンマークにおける散発性カンピロバクター感染症に対するリスク要因の症例対照研究 ) A human health risk assessment for macrolide-resistant Campylobacter associated with the use of macrolides in Danish pig production( デンマークの豚群におけるマクロライド使用に関連したマクロライド耐性カンピロバクターのヒトの健康リスク評価 ) A multicenter evaluation of linezolid antimicrobial activity in North America( 北米におけるリネゾリドの抗菌活性に関する多施設共同評価 ) A risk assessment of the use of bacitracin as growth promoting substance for animals( 食料生産動物に対する抗菌性成長促進剤としてのバシトラシン使用のリスク評価 ) Acquired macrolide resistance genes in pathogenic Neisseria spp. isolated between 1940 and 1987(1940 年から 1987 年の間に分離された病原性 Neisseria 属の獲得マクロライド耐性遺伝子 ) Activity of daptomycin against susceptible and multidrug-resistant Gram-positive pathogens collected in the SECURE study (Europe) during (2000~2001 年の SECURE 試験で収集された感受性及び多剤耐性の病原性グラム陽性菌に対するダプトマイシンの活性 ) Amplification of bacitracin transporter genes in the bacitracin producing Bacillus licheniformis( バシトラシンを産生するバチルス - リケニフォルミスにおけるバシトラシントランスポーター遺伝子の増幅 ) An investigation of the molecular mechanisms contributing to high-level erythromycin resistance in Campylobacter( カンピロバクターにおける高度エリスロマイシン耐性に寄与する分子メカニズムの調査 ) An outbreak of campylobacter enteritis among the staff of a poultry abattoir in Sweden( スウェーデンの鶏肉処理場従業員におけるカンピロバクター腸炎の大発生 ) Antibiotic resistance among enterococci isolated from clinical specimens between 1953 and 1954(1953 年から 1954 年の臨床標本から分離された腸球菌における抗生物質耐性 ). Gillespie, I.A. et al. Neimann, J. et al. Alban, L. et al. (2008) Ballow, C.H. et al. Notermans, S & Hofstra, H. (1998) Cousin, G.G. et al. Critchley, I.A. et al. Podlesek, Z.A. et al. (1997) Corcoran, D. et al. (2006) Christenson, B. et al. (1983) Atkinson, B.A. et al. (1997) Emerg. Infect. Dis. 8, Epidemiol. Infect. 130, Prev Vet Med. 83, Diagn. Microbiol. Infectious Dis. 43, TNO Nutrition and Food Research. TNO Report. 98, 1269 Antimicrob Agents Chemother. 47, Chemother. 51, FEMS Microbiology Letters. 157, Intl J Antimicrob Agents. 27, Scand J Infect Dis. 15, Antimicrob Agents Chemother. 41,

2 0012 Antibiotic resistance in Escherichia coli and Enterococcus spp. Isolates from commercial broiler chickens receiving growth-promoting doses of bacitracin or virginiamycin( 成長促進用量のバシトラシンあるいはバージニアマイシンを給与したコマーシャルブロイラーからの大腸菌及び腸球菌種分離株における抗生物質耐性 ) Antibiotic resistance of faecal enterococci in poultry, poultry farmers and poultry slaughterers( 家禽 家禽生産者及び食鳥処理業者における便中腸球菌の抗生物質耐性 ) Antibiotic sensitivity and mutation rates to antibiotic resistance in Mycoplasma mycoides ssp. Mycoides(Mycoplasma mycoides ssp. mycoides の抗生物質感受性と抗生物質耐性の突然変異率 ) Antibiotic Susceptibilities of Bifidobacterial Strains Distributed in Japanese Market( 日本市場に分布したビフィズス菌株の抗生物質感受性 ) Antibiotic Susceptibilities of Recent Isolates of Mycoplasma bovis in Belgium( ベルギーにおける Mycoplasma bovis の最近の分離株の抗生物質感受性 ) Antibiotic susceptibility of Streptococcus mutans: Comparison of Serotype Profiles(Streptococcus mutans の抗生物質感受性 : 血清型プロファイルの比較 ) Antibiotics studies on beta haemolytic Streptococci, V acquired in vitro resistance to bacitracin(β 溶血連鎖球菌に対する抗生物質試験 :VII. バシトラシンに対する獲得 in vitro 耐性 ) activity of quinupristin-dalfopristin (RP 59500, Synercid) tested against over 28,000 recent clinical isolates from 200 medical centers in the United States and Canada( 米国とカナダの医療所 200 か所で分離された 28,000 株を超える臨床分離株に対するキヌプリスチン - ダルホプリスチン (RP Synercid ) の抗菌活性 ). Thibodeau A. et al. (2008) Van den Bogaard A. E. et al. Lee, D.H. et al. (1987) Xiao J. et al. (2010) Thomas A. et al. Little, W. et al. (1979) Gezon, H.M. et al. (1950) Jones, R.N. et al. (1998) The Canadian Journal of Veterinay Research. 72, Chemother. 49, Epidemiol Infect. 98, Bioscience Biotechnology and Biochemistry. 74 (2), The Veterinary Record. 153, and Chemotherapy. 15(3), Proc. Soc. Exp. Biol. Med. 74, Diagn. Microbiol. Infect. Dis. 30, drug prescriptions in ambulatory care settings, United States, ( 外来診療での抗菌剤処方 ( 米国 1992~2000 年 )). McCaig, L.F. et al. Emerg Infect Dis. 9, of Susceptibility of Bordetella bronchiseptica Isolated from Pigs with Respiratory Diseases on Farms in China ( 中国の農場における呼吸器疾患を有する豚から分離した気管支敗血症菌分離株の抗菌薬感受性 ) Resistance among Campylobacter Strains, Unied States, ( カンピロバクター株における抗菌剤耐性 米国 1997~2001 年 ) 0023 resistance in recent fecal enterococci from healthy volunteers and food handlers in Spain: genes and phenotypes( スペインの健常志願者及び食品取扱業者由来の最近の便中腸球菌の抗菌薬耐性 : 遺伝子及び表現型 ) 0024 Susceptibility of Quinupristin/Dalfopristin Tested Against Gram-Positive Cocci Fro/mLatin America: Results from the Global SMART (GSMART) Surveillance Study( ラテ Zhao, Z. et al. (2011) Gupta, A. et al. (2004) Del Campo, R. et al. Sader, H.S. et al. J.Veterinary Medical Science. 73(1), Emerging Infectious Diseases. 10, 6, June 2004 Microb. Drug Resist. 9,No The Brazilian Journal of Infections 4

3 ンアメリカの由来グラム陽性球菌にするキヌプリスチン / ダルホプリスチンの抗菌薬感受性 : 全世界 SMART サーベイランス ) susceptibility patterns of enterococci in intensive care units in Sweden evaluated by different MIC breakpoint systems( 異なる MIC 区切り点システムによるスウェーデンの集中治療室における腸球菌の抗菌薬感受性パターン ) Association of Campylobacter jejuni with laying hens and eggs ( 産卵鶏及び鶏卵と Campylobacter jejuni の関連 ). Hallgren, A. et al. Doyle, M.P. (1984) Diseases. 5, Chemother. 48, Appl. Environ. Microbiol. 47, Associations between the use of antimicrobial agents for growth promotion and the occurrence of resistance among Enterococcus faecium from broilers and pigs in Denmark, Finland, and Norway( デンマーク フィンランド及びノルウェーにおける成長促進用抗菌剤の使用とブロイラー及び豚由来 E. faecium の耐性発現との関連性 ). Aarestrup, F.M. et al. (2000) Microb. Drug Resistance. 6, Bacillus licheniformis bacitracin-resistant ABC transporter: relationship to mammalian multi-drug resistance(bacillus licheniformis のバシトラシン耐性 ABC トランスポーター : 哺乳類の多剤耐性との関係 ). Podlesek, Z.A. et al. (1995) Molecular Microbiology. 16 (5), Bacitracin Resistant Mutants of a Mesophilic( 中温性メタノバクテリウム種のバシトラシン耐性変異株 ). Harris, J.E.& Methanobacterium Pinn, A. (1985) Species. Arch. Microbiol. 143, Bacteriostatic and Bactericidal Activities of Tigecycline against Coxiella burnetti and Comparison with Those of Six Other Antibiotics(Coxiella burnetii に対するチゲサイクリンの静菌及び殺菌活性ならびに他の抗生物質 6 種の活性との比較 ) Bactrian-induced proteins in Bacillus subtilis and Bacillus thuringiensis and their relationship with resistance(b. subtilis 及び B. thuringiensis におけるバシトラシン誘導性タンパク質ならびにそれらと耐性との関係 ) Baseline Study To Determine In Vitro Activities of Daptomycin against Gram-Positive Pathogens Isolated in the United States in ( 米国で 2000 年から 2001 年に分離された病原性グラム陽性菌に対するダプトマイシンの in vitro 活性を判定するためのベースライン試験 ) Benefits and microbiological risks of feed additive antibiotics ( 飼料添加抗生物質の有益性及び微生物学的リスク ) Birds, migration and emerging zoonoses: West Nile virus, Lyme disease, influenza A and enteropathogens( 鳥類 渡りと人獣共通感染症 : 西ナイルウイルス ライム病 A 型インフルエンザ及び腸病原体 ). Spyridaki I. et al. (2009) Garcia-Patrone, M. (1990) Critchley, I.A. et al. Bywater, R.J. (1998) Reed, K.D. et al. Chemotherapy. 53 (6), Chemotherapy. 34 (5), Chemother. 47,No.5, CIHEAM-Options Mediterraneennes Clin Med Res. 1, Campylobacter in the food supply( 食品供給におけるカンピロバクター ). Jacobs - Reitsma, W. et al. (2008) Campylobacter, 3rd ed. American Society for Microbiology, Washington, D.C.,

4 0036 Campylobacter jejuni infection as a hospital problem: an Butzler, J. P. & H. J. Hospital Infect. overview( 院内問題としてのCampylobacter jejuni 感染 : 概説 ) Goosens. (1988) 11, SplA, Characterization of a new enterococcal gene, satg, encoding a putative acetyltransferase conferring resistance to streptogramin A compounds( ストレプトグラミン A 化合物に対する耐性を与える推定アセチルトランスフェラーゼをコードする新たな腸球菌遺伝子 satg の特性決定 ) Characterization of erythromycin resistance in Campylobacter coli and Campylobacter jejuni isolated from pig offal in New Zealand( ニュージーランドにおいて豚の内臓から分離された C. coli 及び C. jejuni の特徴 ) Characterization of erythromycin-resistant isolates of Staphylococcus aureus recovered in the United States from 1958 through 1969(1958~1969 年に米国で回収された Staphylococcus aureus のエリスロマイシン耐性分離株の解析 ) Characterization of vancomycin-resistant Enterococcus faecium isolates from the United States and their susceptibility in vitro to dalfopristin-quinupristin( 米国からのバンコマイシン耐性 E. faecium 分離株の特性評価及びその in vitro におけるダルホプリスチン キヌプリスチンに対する感受性 ) Classification of macrolide antibiotics( マクロライド系抗生物質の分類 ) Clinical prevalence, antimicrobial susceptibility, and geographic resistance patterns of enterococci: results from the SENTRY Surveillance Program, ( 腸球菌の臨床的蔓延率 抗菌薬感受性及び地理的耐性パターン :1997~ 1999 年の SENTRY 抗菌薬サーベイランス プログラムからの結果 ) Clinical prevalence, antimicrobial susceptibility, and geographic resistance patterns of enterococci: results from the SENTRY antimicrobial surveillance program, ( 腸球菌の臨床罹患率 抗菌薬感受性及び地理的耐性パターン : SENTRY 抗菌剤耐性サーベイランス プログラム 1997~1999 年 ) 0044 Cluster of erythromycin- and ciprofloxacin-resistant Campylobacter jejuni subsp. jejuni from 1999 to 2001 in men who have sex with men, Quebec, Canada( カナダ ケベック州の男性と性行為を持つ男性における 1999 年 年のエリスロマイシン及びシプロキサシン耐性の C. jejuni subsp. jejuni). Werner G. & Witte. (1999) Harrow, S.A. et al. (2004) Nicola, F.G. et al. (1998) Eliopoulos, G.M. et al. (1998) Bryskier, A. et al. (1993) Low, D.E. et al. Low, D.E. et al. Gaudreau, C. & S.Michaud. Chemotheroy. 43, No.37, J. Appl. Microbiol. 97, Antimicrob Agents Chemother. 42, Chemother. 42(5), Macrolides chemistry, pharmacology and clinical uses Clin. Infect. Dis. 32 Suppl 2, S133-S145 Clin Infect Dis. 32, S133-S145 Clin Infect Dis. 37, Comparative In Vitro Activity of Doxycyline and Oxytetracycline against Porcine Respiratory Pathogens( 豚の呼吸器病原体に対するドキシサイクリン及びオキシテトラサイクリンの in vitro 活性の比較 ). Bousquet, E. et al. (1997) The Veterinary Record. 141, Comparative in vitro activity of quinupristin/dalfopristin against multidrug resistant Enterococcus faecium( 多剤耐性 E. faecium に対するキヌプリスチン / ダルホプリスチンの in vitro 活性比較 ). Bonilla, H.F. et al. (1996) Diagn. Microbiol. Infectious Dis. 25,

5 0047 Comparative In-vitro Activity of Levofloxacin, against Chlamydia spp(chlamydia 属に対するレボフロキサシンの in vitro 活性の比較 ) Comparative Killing Kinetics of Methicillin-Resistant Staphylococcus aureus by Bacitracin or Mupirocin( バシトラシンあるいはムピロシンによるメチシリン耐性黄色ブドウ球菌の死滅動態の比較 ). Donani, M. et al. (1998) Chapnick, E.K. et al. (1996) Journal of Antimicrob. Chem.48, Infection Control and Hospital Epidemiology. Mar-96, Comparison of antimicrobial resistance phenotypes and resistance genes in Enterococcus faecalis and Enterococcus faecium from humans in the community, broilers, and pigs in Denmark Diagonostic( デンマークにおけるヒト ブロイラー及び豚由来の E. faecalis 及び E. faecium の抗菌薬耐性表現型及び耐性遺伝子の比較 ). Aarestrup, F.M. et al. (2000) Diagnostic Microbiology and Infectious Disease. 37, Comparison of In Vitro Activity of Danofloxacin, Florfenicol, Oxytetracycline, Spectinomycin and Tilmicosin against Recent Field Isolates of Mycoplasma bovis( 最近の Mycoplasma bovis 野生分離株に対するダノフロキサシン フロルフェニコール オキシテトラサイクリン スペクチノマイシン及びチルミコシンの in vitro 活性の比較 ) Comparison of Methods for In Vitro Testing of Susceptibility of Porcine Mycoplasma Species to Agents( 抗菌剤に対する豚のマイコプラズマ種の感受性に関する in vitro 検査方法の比較 ) Contemporary antimicrobial activity of triple antibiotic ointment: a multiphased study of recent clinical isolates in the United States and Australia( 三剤配合抗生物質軟膏の現在の抗菌活性 : 米国及びオーストラリアの最近の臨床分離株に関する多相試験 ) Contribution of the CmeABC efflux pump to macrolide and tetracycline resistance in Campylobacter jejuni( マクロライド及びテトラサイクリン耐性における CmeABC 排出ポンプの寄与 ) Cross-Resistance among 3 Tetracyclines(3 種のテトラサイクリン系抗生物質間の交差耐性 ) Decreased susceptibility to Azithromycin and Doxycycline in Clinical Isolated of Chlamydia trachomatis Obtained from Recurrently Infected Female Patients in India( インドの再発性感染症女性患者由来の Chlamydia trachomatis 臨床分離株におけるアジスロマイシン及びドキシサイクリン感受性の低下 ) Defective killing of enterococci: a common property of antimicrobial agents acting on the cell wall( 腸球菌の不完全な死滅 : 細胞壁に作用する抗菌剤の共通特性 ) Detection and survival of Campylobacter in chicken eggs( 鶏卵におけるカンピロバクターの検出及び残存 ). Ayling R.D. et al. (2000) Ter Laak, EA. et al. (1991) Ronald, N. J. et al. (2006) Gibreel, A. et al. (2007) Wright, SS. & Finland, M. (1954) Bhengraj, AR. et al. (2010) Krogstad, D.J. & Parquette, A.R. (1980) Sahin, O. et al. The Veterinary Record. 146, Agents of Chemotherapy. 35 (2), Diagnostic Microbiology and Infectious Disease. 54, Antimicrob Agents Chemother. 51, Proceedings of the Society for Experimental Biology and Medicine. 85, Chemotherapy. 56 (5), Agents & Chem. 24, J. Appl. Microbiol. 95,

6 0058 Detection of the sata gene and transferability of virginiamycin resistance in Enterococcus faecium from food-animals( 食用動物由来 Enterococcus faecium における sata 遺伝子の検出及びバージニアマイシン耐性の伝達可能性 ). Hammerum, A.M. et al. (1998) FEMS Microbiol. Letters. 168, Detection of thermophilic Campylobacter from sparrows by multiplex PCR: the role of sparrows as a source of contamination of broiler with Campylobacter( 多重 PCR によるスズメからの好熱性カンピロバクターの検出 : ブロイラーのカンピロバクター汚染の源としてのスズメの役割 ) Determination of Mycoplasma bovis susceptibilities against six antimicrobial agents using the E test method(e テストによる 6 種類の抗菌薬に対する Mycoplasma bovis の感受性の測定 ) 0061 Differences in Antibiotic Resistance Patterns of Enterococcus faecalis and Enterococcus faecium Strains Isolated from Farm and Pet Animals( 家畜及びペット動物から分離された E. faecalis 及び E. faecium 株の抗生物質耐性パターンの相違 ) Differential antimicrobial susceptibility between human and chicken isolates of vancomycin-resistant and sensitive Enterococcus faecium( ヒト及び鶏由来バンコマイシン耐性及び感受性 E. faecium 分離株の抗菌剤感受性の差 ) Differential effects of temperature on natural transformation to erythromycin and nalidixic acid resistance in Campylobacter coli(campyrobacter coli のエリスロマイシン及びナリジクス酸耐性への自然形質転換に対する温度の区別的影響 ) Distribution and numbers of Campylobacter in newly slaughtered broiler chickens and hens( 新たに食肉処理されたブロイラー及び雌鶏におけるカンピロバクターの分布及び数 ) Diversity of Tetracycline Resistance Genes in Bacreria Isolates from Various Agriculture Environment( さまざまな農業環境から分離された細菌のテトラサイクリン耐性遺伝子の多様性 ) Double-blind placebo controlled trial of erythromycin for treatment of campylobacter enteritis( カンピロバクター腸炎の治療についてのエリスロマイシンの二重盲検プラセボ対照試験 ) Effect of bacitracin on tetracycline resistance in Escherichia coli and Salmonella( 大腸菌及びサルモネラ菌におけるテトラサイクリン耐性に対するバシトラシンの効果 ) Effect of bacitracin on transfer of R plasmids(r プラスミドの伝達に及ぼすバシトラシンの影響 ) Effect of macrolide usage on emergence of erythromycin-resistant Campylobacter isolates in chickens( 鶏におけるエリスロマイシン耐性カンピロバクター分離株の出現に対するマクロライド使用の影響 ) Effects of subtherapeutic administration of antimicrobial agents to beef cattle on the prevalence of antimicrobial resistance in Campylobacter jejuni and Campylobacter hyointestinalis(c. jejuni 及び C. hyointestinalis における抗菌剤耐性の保有率に Chuma, T. et al. (2000) Francoz D. et al. (2005) Butaye, P. et al. Chen, H.Y. et al. Kim J.S. et al. (2008) Berndtson, E. et al. (1992) Kobashi Y. et al. (2007) Anders, B.J. et al. (1982) Lin, J. et al. (2009) Kruse, H. et al. (1995) Lin, J. et al. (2007) Inglis, G.D. et al. (2005) J. Vet Med Sci. 62, Veterinary Microbiology. 105 (1), Chemother. Int. Agents. 19, Applied and Environmental microbiology. 74, Intl. J. Food Microbiol. 15, Microbes and Environments. 22 (1), Lancet. Ii, Veterinary Microbiology. 138, Submission for publication. Chemother. 51, Appl. Environ. Microbiol. 71,

7 対する肉牛への治療量以下の抗菌剤投与の影響 ) Epidemiology of Campylobacter jejuni infections in the United States and other industrialized nations( 米国及びその他の先進国における Campylobacter jejuni 感染症の疫学 ) Erythromycin in treatment of Campylobacter enteritis in children( エリスロマイシンによる小児カンピロバクター腸炎の治療 ) Evaluation of Antibiotics Susceptibilities of Three Rickettsial Species Including Rickettsia felis by a Quantitive PCR DNA Assay( 定量的 PCR DNA アッセイによる Rickettsia felis を含むリケッチア 3 種の抗生物質感受性評価 ) Evaluation of in vitro activity of quinupristin/dalfopristin and comparator antimicrobial agents against worldwide clinical trial and other laboratory isolates( 全世界的臨床試験及びその他の検査室の分離株に対するキヌプリスチン / ダルホプリスチン及び比較対照抗菌薬の in vitro 活性の評価 ) Experimental Campylobacter jejuni infection in humans( ヒトにおける実験的 Campylobacter jejuni 感染 ) Factors associated with increased and decreased risk of Campylobacter infection: a prospective case-control study in Norway( カンピロバクター感染のリスク上昇及び低下に関連した要因 : ノルウェーにおける前向き症例対照研究 ) Food-related illness and death in the Unites States.( 米国における食品関連の疾患と死亡 ) 0078 Gastrointestinal tract colonization with vancomycin-resistant Enterococcus faecium in an animal model( 動物モデルにおけるバンコマイシン耐性 E. faecium による消化管コロニー形成 ) Gastrointestinal transit survival of an Enterococcus faecium probiotic strain administered with or without vancomycin( バンコマイシンと併用投与または単独投与した E. faecium プロバイオティック株の消化管通過による生存性 ) Generation of Campylobacter jejuni genetic diversity in vivo (Campylobacter jejuni の遺伝子多様性の in vivo での発生 ). Friedman, C.R. et al. (2000) Pai, C.H. et al. (1983) Rolain, JM. et al. Dowzicky, M. et al. (1998) Black, R.E. et al. (1988) Kapperud, G. et al. Mead, P.S. et al. (1999) Whitman, M.S. et al. (1996) Lund, B. et al. de Boer, P. et al. Campylobacter, 2nd ed. American Society for Microbiology. Washington, D.C Am. J. Dis. Child. 137, Chemotherapy. 46 (9), Am. J. Med. 104 (5A), 34S-42S. J. Infect. Dis. 157, Am. J. Epidemiol. 158, Emerg Infect Dis. 5, Chem. 40(6), International J. Food Microbiol. 77, Mol Microbiol. 44, Genetic analysis of antibiotic resistance in Streptococcus pyogenes(s. pyogenes における抗生物質耐性の遺伝子分析 ) Horizontal Transfer Of The sata Gene Encoding Streptogramin A Resistance Between Isogenic Enterococcus faecium Strains In The Gastrointestinal Tract of Gnotobiotic Rats( ノトバイオートラット消化管の E. faecium 同質遺伝子系統株間におけるストレプトグラミン A 耐性をコードする sata 遺伝子の水平伝播 ). Stuart, J.G. & Ferretti, J.J. (1978) Jacobsen, B.L. et al. (1999) J. Bacteriol. Feb, Microbial Ecology in Health and Disease. 11,

8 0083 Identification and molecular characterization of CmeB, a Campylobacter jejuni multidrug efflux pump(c. jejuni 多剤排出ポンプ CmeB の同定及び分子解析 ). Pumbwe, L., &Piddock, L.J.V. FEMS Microbiol Lett. 206, Identification and molecular epidemiology of Campylobacter coli isolates from human gastroenteritis, food and animal sources by amplified fragment length polymorphism analysis and Penner serotyping( 増幅断片長多性解析及び Penner 血清型決定によるヒト胃腸炎 食物及び動物からの Campylobacter coli 分離株の同定及び分子疫学 ) Identification of the sata gene encoding a streptogramin A acetyltransferase in Enterococcus faecium BM4145(E. faecium BM4145 におけるストレプトグラミン A アセチルトランスフェラーゼをコードする sata 遺伝子の同定 ). Siemer, B.L. et al. (2005) Appl. Environ. Microbial. 71, Rende-Fournier, R. et al. (1993) Chemotherpy. 37 (10), Identification of vat (E)in Enterococcus faecalis isolates from retail poultry and its transferability to Enterococcus faecium( 市販家禽肉由来の E. faecalis 分離株中の vat(e) の同定及び E. faecium への追跡可能性 ) In Vitro Activity of CEM-101, a New Fluoroketolide Antibiotics, against Chlamydia trachomatis and Chlamydia (Chlamydophila) pneumoniae(c. trachomatis 及び C. (Chlamydophila)pneumoniae に対する新規フルオロケトライド抗生物質 CEM-101 の in vitro 活性 ) In vitro analytical system for determining the ability of antibiotics at residue levels to select for resistance in bacteria( 細菌における耐性を選択する残留レベルの抗生物質の能力を判定するための in vitro 分析システム ) In Vitro and In Vivo Activities of AM-1155, a New Fluoroquinolone, against Chlamydia spp(am-1155( クラミジア種に対する新規のフルオロキノロン ) の in vitro 及び in vivo 活性 ) In vitro and in vivo methodology for detecting and evaluating inhibitors of transfer of resistance bacteria( 耐性因子転移阻害物質を検出及び評価するための in vitro 及び in vivo の方法 ) In Vitro Antibiotics Susceptibility of Field Isolated of Mycoplasma synoviae in Argentina( アルゼンチンにおける Mycoplasma synoviae の野生分離株の in vitro 抗生物質感受性 ) In Vitro Inhibition Profiles of Mycoplasma bovis Isolates Recovered from Various Regions of United States from 2002 to 2003(2002~2003 年に米国の様々な地域で分離された M. bovis 分離株の in vitro 抗菌抑制プロフィール ) In vitro antimicrobial susceptibilities of 349 Methicillin-resistant Staphylococcus aureus isolates from veterans( 退役軍人からのメチシリン耐性 S. aureus349 株の in vitro 抗菌薬感受性 ) In vitro Gram-positive antimicrobial activity of evernimicin (SCH 27899), a novel oligosaccharide, compared with other antimicrobials: a multicentre international trial( 新規オリゴ糖であるエベルニマイシン (SCH 27899) と他の抗菌薬の in vitro 抗グラム陽性菌活性の比較 : 多施設国際試験 ). Simjee, S. et al. 2002) Robin, PM. et al. (2010) Brady, M.S. et al. (1988) Miyashita, N. et al. (1997) Ott, J.L. et al. (1971) Cerdá R.O. et al. Rosenbusch R.F. et al. (2005) Flournoy, D.J. & Robinson, M.C. (1990) Jones, R. N. et al. (Antimicrob Agents Chemother. 46, Chemotherapy. 54 (3), J. Assoc. Off. Anal. Chem. 71(2), Chemotherapy. 41 (6), Ann. N.Y. Acad. Sci. 182, Avian Disease. 46, J. Vet. Diagnostic Investigation. 17, Meth. Find. Exp. Clin. Pharmacol. 12(8), Chemother. 47,

9 0095 In Vitro Susceptibilities of Coxiella burnetii to Linezoid in Comparison with Its Susceptibilities to Quinolones, Doxycycline, and Clarithromycin(Coxiella burnetii のリネゾリドに対する in vitro 感受性とキノロン類 ドキシサイクリン及びクラリスロマイシンに対する感受性の比較 ) In Vitro Susceptibilities of 27 Rickettsiae to 13 s ( 抗生物質 13 種に対する 27 のリケッチアの in vitro 感受性 ) In Vitro Susceptibilities to Tetracycline and Fluoroquinolones of 27 Japanese Isolates of Coxiella burnetii(coxiella burnetii の日本分離株のテトラサイクリン及びフルオロキノロン類に対する in vitro 感受性 ) In Vitro Susceptibility of Avian Mycoplasmas to Enrofloxacin, Sarafloxacin, Tylosin, and oxytetracycline( エンロフロキサシン サラフロキサシン タイロシン及びオキシテトラサイクリンに対する鳥類マイコプラズマの in vitro 感受性 ) In vitro susceptibility of Clostridium perfringens isolated from farm animals to growth-enhancing antibiotics( 家畜から分離されたウェルシュ菌の成長促進抗生物質に対する in vitro 感受性 ) In vitro susceptibility of Enterococcus faecium isolated from food to growth-promoting and therapeutic antibiotics( 食品から分離された E. faecium の成長促進及び治療用抗生物質に対する in vitro 感受性 ). Gikas A. et al. Rolain, JM. et al. (1998) Andoh, M. et al. (2004) Wang, C. et al. Devriese, L.A. (1993) et al. Butaye, P. et al. (2000) Chemotherapy. 45 (11), Chemotherapy. 42 (7), Microbiology and Immunology. 48 (9), Avian Disease. 45, J. Appl. Bacteriol. 75, 55-7 Int. J. Food Microbiol. 54, Inducible transfer of conjugative transposon Tn1545 from Enterococcus faecalis to Listeria monocytogenes in the digestive tracts of gnotobiotic mice( ノトバイオート マウスの消化管における Enterococcus faecalis から Listeria monocytogenes への接合トランスポゾン Tn1545 の誘導性転移 ) Induction of van A vancomycin resistance genes in Enterococcus faecalis: Use of a promotor fusion to evaluate glycopeptide and nonglycopeptide induction signals (Enterococcus faecalis における vana バンコマイシン耐性遺伝子の誘導 : 糖ペプチド及び非糖ペプチド誘導シグナルの評価へのプロモーター融合の利用 ). Doucet-Populaire, Antimicrob Agents F. et al. (1991) Chemother. 35, Grissom-Amold, Mirobial Drug J. et al. (1997) Resistance. 3(1), Induction of vancomycin resistance in Enterococcus faecium by non-glycopeptide antibiotics( 非糖ペプチド抗生物質による E. faecium におけるバンコマイシン耐性の誘導 ) Inhibition of protein synthesis by streptogramins and related antibiotics( ストレプトグラミン及び類縁抗生物質によるタンパク質合成の阻害 ). Allen, N.E. & Hobbs Jr., J.N. (1995) Cocito, C. et al. (1997) FEMS Microbiology Letters. 132, Chem. 39(Suppl. A), Investigating the efficacy of macrolide use in human Campylobacter infections and the relationship between macrolide resistance and adverse treatment outcomes( ヒトのカンピロバクター感染におけるマクロライド使用の有効性及びマクロライド耐性と有害な治療アウトカムの関係に関する調査 ). Aramini, J. & J. Novometrix Wilson. (2008) Research Inc. 11

10 0106 In-vitro Evaluation of Activity of Azithromycin, Erythromycin, and Tetracycline against Chlamydia trachomatis and Chlamydia pneumoniae(c. trachomatis 及び C. pneumoniae に対するアジスロマイシン エリスロマイシン及びテトラサイクリンの活性の in vitro 評価 ) 0107 Involvement of the CmeABC efflux pump in the macrolide resistance of Campylobacter coli(campylobacter coli のマクロライド耐性への CmeABC 排出ポンプの関与 ) Isolation and susceptibilities of Chlamydial Isolates from Western Barred Bandicoots( ニシシマバンディクート由来クラミジア分離株の分離及び抗菌薬感受性 ) Local antiseptics versus antibiotics in topical therapy - the emergence of microbial resistance( 局所治療における局所消毒薬と抗生物質の比較 - 微生物の耐性の出現 ) Loss of Resistance to the Tetracyclines from Porcine Escherichia coli in Contact with Dietary Bacitracin Methylene Disalicylate( 飼料中のバシトラシンメチレンジサリチレートに接した豚分離大腸菌からのテトラサイクリンに対する耐性の消失 ) Macrolide resistance genes in Enterococcus spp(enterococcus 属におけるマクロライド耐性 ) Macrolide resistance in Campylobacter coli of animal origin in Denmark( デンマークにおける動物由来 Campyrobacter coli のマクロライド耐性 ). Welsh, L.E. et al. (1992) Cagliero, C. et al. (2005) Kumar, S. et al. (2007) Kessler, H. J. (1980) Walton, J.R. & Wheeler, J.E. (1987) Portillo, A. et al. (2000) Jensen, L.B., & F. M. Aarestrup. Chemotherapy, 36 (2), Chemother. 6, J. Clinical Microbiology. 45, Mykosen. 23(6), J. Vet. Med. B. 34, Chemotherpy. 44 (4), Chemother. 45, Macrolide resistance in Campylobacter jejuni and Campylobacter coli( マクロライド耐性 C. jejuni 及び C. coli). Gibreel A. & D.E. Taylor. (2006) Chemother. 58, Macrolide, lincosamide and streptogramin resistance in Campylobacter jejnui/coli(campylobacter jejuni/coli におけるマクロライド リンコサマイド及びストレプトグラミン耐性 ) Macrolide-resistant Campylobacter: the meat of the matter( マクロライド耐性カンピロバクター : 問題の食肉 ) Macrolides amd Lincomycin Susceptibility of Mycoplasma hyorhinis and Variable Mutation of Domain Ⅱand Ⅴ in 23S Ribosomal RNA(Mycoplasma hyorhinis のマクロライド系及びリンコマイシン感受性ならびに 23S リボソーム RNA のドメイン II 及び V の多様な突然変異 ) Major structural differences and novel potential virulence mechanisms from the genomes of multiple Campylobacter species( 複数のカンピロバクターにおける遺伝子構造の主要な差異と新規潜在的毒力の機序 ) Method to determine effect of antibiotica at residue level on R-factor transfer( 残留レベルの抗生物質が R 因子伝達に及ぼす影響の判定法 ). Burridge, R. et al. (1986) Belanger, A.E. & T.R. Shryock. (2007) Kobayashi H. et al. (2005) Fouts, D.E. et al. (2005) Brady, M.S. et al. (1988) Chemother. 17, Chemother. 60, J.Vet. Medical Sci. 67(8), PLoS Biol. 3, J. Assoc. Off. Anal. Chem. 71(2),

11 0119 Molecular basis of macrolide resistance in Campylobacter: role of efflux pumps and target mutations( カンピロバクターにおけるマクロライド耐性の分子基盤 : 排出ポンプ及び標的突然変異の役割 ) Molecular Characterization and Determination of Resistance of Mycoplasma gallisepticum Isolated from Chickens ( 鶏から分離された Mycoplasma gallisepticum の分子生物学的特性決定と抗菌薬耐性の測定 ) 0121 Most Campylobacter subtypes from sporadic infections can be found in retail poultry products and food animals( 散発感染由来カンピロバクターのサ豚イプの多くは市販家禽肉及び食用動物に認められる ) Multicentre evaluation of the in vitro activity of linezolid in the Western Pacific( 西太平洋におけるリネゾリドの in vitro 活性に関する多施設評価 ) Multi-laboratory assessment of the linezolid spectrum of activity using the Kirby-Bauer disk diffusion method: Report of the Zyvox(R) Potency Study (ZAPS) in the United States(Kirby-Bauer ディスク拡散法を用いたリネゾリド抗菌スペクトルの多施設評価 : 米国における Zyvox 抗菌効力試験 ) Multiple-drug resistant enterococci: the nature of the problem and the agenda for the future( 多剤耐性腸球菌 : 問題及び今後の検討課題の性質 ) Natural transformation-mediated transfer of erythromycin resistance in Campylobacter coli strains from turkeys and swine ( 七面鳥及び豚由来 C. coli におけるエリスロマイシン耐性の自然形質転換介在遺伝子導入 ) Nomenclature for Macrolide and Macrolide-Lincosamide- Streptogramin B Resistance Determinants( マクロライド及びマクロライド - リンコサマイド - ストレプトグラミン B 耐性決定因子の術語体系 ). Mamelli L. et al. (2005) Pakpinyo, S. & Sasipreeyajan, J. (2007) Nielsen, E.M. et al. (2005) Bell, J.M. et al. Jones, R.N. et al. Huycke, M.M. et al. (1998) Kim, J.S. et al. (2006) Roberts, M.C. et al. (1999) Chemother. 56, Veterinary Microbiology. 125 (1-2), Epidemiol Infect , 1-10 Chemother. 51, Diagn. Microb. Infectious Dis. 40, Emerg. Infect. Dis. 4, Appl. Environ. Microbiol. 72, Chemotherpy. 43 (12), Occurrence of Campylobacter jejuni in pets living with human patients infected with C. jejuni.(c. jejuni に感染したヒト患者と生活するペットにおける C. jejuni の出現 ). Damborg, P. et al. (2004) J. Clin, Microbiol. 42, Occurrence of sata and vgb genes in streptogramin-resistant Enterococcus faecium isolates of animal and human origins in the Netherlands ( オランダの動物及びヒト由来ストレプトグラミン耐性 E. faecium 分離株における sata 及び vgb 遺伝子の発生 ) Pharmacokinetic/pharmacodynamic parameters: rationale for antimicrobial dosing of mice and men( 薬物動態学 / 薬力学パラメータ : マウスとヒトの抗菌薬投与法の理論的根拠 ) Phenotypic distinction in Enterococcus faecium and Enterococcus faecalis strains between susceptibility and resistance to growth - enhancing antibiotica(e. faecium 及び E. faecalis の表現型による成長促進抗生物質に対する感受性と耐性の識別 ). Jensen, L.B. et al. (1998) Craig, W. A. 1998) Butaye P.B et al. (1999) Chemotherpy. 42 (12), (Clin. Infect. Dis. 26, 1-12 American Society for Microbiology

12 0131 Presence of erm gene classes in gram-positive bacteria of animal and human origin in Denmark( デンマークの動物及びヒト由来グラム陽性細菌における erm 遺伝子クラスの存在 ) Prevalence and Resistance of Enterococcus spp. Isolated from Retail Meats( 小売り肉から分離された腸球菌種の保有率及び抗菌剤耐性 ) Prevalence of Campylobacter within a swine slaughter and processing facility( 豚屠殺 加工施設内のカンピロバクターの発生状況 ) Prevalence of multiple antibiotic resistance in 443 Campylobacter spp. isolated from humans and animals( ヒト及び動物から分離された 443 株の Campylobacter 属菌における抗生物質多剤耐性の発生状況 ) Prevalence of resistance to /MLS antibiotics in 20 European university hospitals participating in the European SENTRY surveillance programme( 欧州 SENTRY 抗菌薬サーベイランス プログラムに参加した欧州の 20 ヵ所の大学病院における /MLS 抗生物質に対する耐性の保有率 ) Public Health Consequences of Macrolide Use in Food Animals: A Deterministic Risk Behavior( 食用動物におけるマクロライド使用の公衆衛生に対する影響 : 決定論的リスク評価 ) Quantification of Campylobacter species cross-contamination during handling of contaminated fresh chicken parts in kitchens ( 調理場における汚染された新鮮な鶏部分肉の取り扱い中のカンピロバクター種交差汚染の定量化 ) Quantification of cell proliferation and alpha-toxin gene expression of Clostridium perfringens in the development of necrotic enteritis in broiler chickens( ブロイラーにおける壊死性腸炎の発症におけるウェルシュ菌の細胞増殖及びアルファ溶血毒遺伝子発現の定量化 ) Quinolone-resistant Campylobacter infections in Denmark: risk factors and clinical consequences( キノロン耐性カンピロバクター感染症 : リスクファクター及び臨床的帰結 ) Quinupristin/dalfopristin-resistant enterococci of the sata (vatd) and satg (vate) genotypes from different ecological origins in Germany( ドイツにおける生態学的起源の異なる sata(vatd) 及び satg(vate) 遺伝子型のキヌプリスチン / ダルホプリスチン耐性腸球菌 ) Quinupristin-dalfopristin resistance among gram-positive bacteria in Taiwan( 台湾におけるグラム陽性細菌のキヌプリスチン ダルホプリスチン耐性 ) Quinupristin-dalfopristin-resistant Enterococcus faecium on chicken and in human stool specimens( 鶏肉上及びヒトの糞便標本中のキヌプリスチン - ダルホプリスチン耐性 E. faecium) Risk factors for domestic sporadic campylobacteriosis among young children in Sweden( スウェーデンの幼児における家庭内散発性カンピロバクター症の危険因子 ). Jensen, L.B. et al. (1999) Hayes, J.R. et al. Pearce, R.A. et al. Randall, L.P. et al. Schmitz, F. J. et al. (1999) Hurd, H.S. et al. (2004) Luber, P. et al. (2006) Weiduo, Si. et al. (2007) Engberg, J. et al. (2004) Werner, G. et al. (2000) Luh, K. T. et al. (2000) McDonald, L.C. et al. Carrique-Mas, J. et al. (2005) FEMS Microbiol. Lett. 170, Appl. Environ. Microbiol.69(12), J. Food Prot. 6, Chemother. 52, Chemother. 43, J. Food Prot. 67(5), Appl. Environ. Microbiol. 72, Applied and Environmental Microbiology. 73 (21), Emerg Infect Dis. 10, Microb. Drug Resist. 6(1) Chem. 44(12), N. Engl. J. Med. 345, Scand J Infect Dis. 37,

13 0144 Role of Salmonella multidrug effux pumps in tigecycline resistance( チゲサイクリン耐性における Salmonella 多剤排出ポンプの役割 ) Seasonal variation of Campylobacter types from human cases, veterinary cases, raw chicken, milk and water( ヒト 動物 生鶏肉 牛乳及び水由来カンピロバクターの型の季節変動 ) Spatial distribution and registry-based case-control analysis of Campylobacter infections in Denmark, ( デンマークにおける 1991 年から 2001 年のカンピロバクター感染症の空間分布及び登録に基づく症例対照分析 ) Specific detection of Arcobacter and Campylobacter strains in water and sewage by PCR and fluorescent in situ hybridization (PCR 及び蛍光 in situ ハイブリダイゼーションによる水中及び下水中のアーコバクター及びカンピロバクターの検出 ) Specificity of induction of glycopeptide resistance genes in Enterococcus faecalis(e. faecium における糖ペプチド耐性遺伝子誘導の特異性 ) Streptogramin resistance among Enterococcus faecium isolated from production animals in Denmark in 1997(1997 年にデンマークの畜産動物より分離された E. faecium のストレプトグラミン耐性 ) Study on the action of zink bacitracin in vitro on transconjugants of Escherichia coli eliminating the development of drug resistance( 大腸菌接合完了体に対する薬物耐性発現を排除する亜鉛バシトラシンの作用に関する in vitro 試験 ) Survey of Resistant Enterococci in Animals( 動物における抗菌薬耐性腸球菌の調査 ) Susceptibility of enterococcus to eleven antibiotics in vitro(11 種類の抗生物質に対する腸球菌の in vitro 感受性 菌種の相違を特別に参照してー ) Synergy between efflux pump CmeABC and modifications in ribosomal proteins L4 and L22 in conferring macrolide resistance in Campylobacter jejuni and Campylobacter coli(c. jejuni 及び C. coli へのマクロライド耐性付与における排出ポンプ CmeABC とリボソームタンパク質 L4 及び L22 の修飾の相乗効果 ). Horiyama T. et a1.(2011). Hudson, J. A. et al. (1999) Ethelberg, S. et al. (2005) Moreno, Y. et al. Baptista, M. et al. (1996) Jensen, L.B. et al. Bineva, I. & Karaivanov, L. (1984) Zervos, M. J. Jones, W.F., Jr. & M. Finland. (1957) Cagliero C. et al. (2006) Chem. 66, J. Appl. Microbiol. 87, Am. J. Epidemiol. 162, Appl. Environ. Microbiol. 69, Antimicrob.Agents and Chemotherapy. 40(10), Microb. Drug Resist. 8, Vet. Sci. 21(1), Final Report. FDA Grant FD-U Am. J. Clin. Path. 27, Chemother. 11, Tetracycline resistome( テトラサイクリンレジストーム ) Maulik R. et al. (2010) Cell. Mol. Life Sci. 67, The Effect of Dietary Zinc Bacitracin on the Resistance Status of Intestinal Escherichia coli and Enterococci from broiler chickens( ブロイラーから分離した腸内大腸菌及び腸球菌の耐性状況に対する飼料中亜鉛バシトラシンの影響 ) The efficacy and safety of quinupristin/dalfopristin for the treatment of infections caused by vancomycin-resistant Enterococcus faecium( バンコマイシン耐性 E. faecium 感染症の治療におけるキヌプリスチン / ダルホプリスチンの有効 Walton, J.R. (1984) Moellering, R.C. et al. (1999) Zentralbl. Veterinaermed. B. 31, 1-8 Chemother. 44,

14 性と安全性 ) The influence of immunity on raw milk associated Campylobacter infection( 生乳関連カンピロバクター感染に対する免疫の影響 ) The occurrence of Campylobacter subtypes in environmental reservoirs and potential transmission routes( 環境内保菌者における Campylobacter サ豚イプの発生及び潜在的伝染経路 ) Transient intestinal carriage after ingestion of antibiotic-resistant Enterococcus faecium from chicken and pork( 鶏肉及び豚肉由来の抗生物質耐性 E. faecium 摂取後の一時的な腸内保菌 ) Variation within the vat(e) allele of Enterococcus faecium isolates from retail poultry samples( 小売り家禽肉検体由来の E. faecium 分離株の vat(e) 対立遺伝子内の変化 ). Blaser, M.J. et al. (1987) Devane, /ML. et al. (2005) Sorensen, T.L. et al. Simjee, S. et al. J. Am. Med. Assoc. 257, J. Appl. Microbiol. 98, N. Engl. J. Med. 345 (16), Chemother. 45,

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