USP Endotoxin Limits for Common Injectables

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Elinor Elliott
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1 Updated as of August 2011 For reference use only

2 This table is for informational purposes only. Endotoxin limits should be set on an individual product basis, using the formula found in the Pharmacopeias ( = K/M). A Acepromazine Maleate Injection Acetazolamide for Injection Acetic Acid Irrigation Acyclovir for Injection Adenosine Injection (continuous peripheral intravenous infusion) Adenosine Injection (rapid intravenous) Alcohol in Dextrose Injection Alfentanil Injection EU / mg EU / mg 10 EU / ml Alprostadil Injection 0.05 EU / µg Alteplase for Injection Amifostine for Injection Amikacin Sulfate Injection Aminocaproic Acid Injection Aminohippurate Sodium Injection Aminopentamide Sulfate Injection Aminophylline Injection Ammonium Chloride Injection (of Chloride) Amobarbital Sodium for Injection Amoxicillin, Sterile and Suspension Amphotericin B for Injection (for Intrathecal) Amphotericin B for Injection (for Parenterals) Ampicillin and Sulbactam for Injection Ampicillin for Injection Anileridine Aprotinin Injection Arginine Hydrochloride Injection Ascorbic Acid Injection Atenolol Injection Atracurium Besylate Injection Atropine Sulfate Aurothioglucose Suspension Azathioprine Sodium for Injection Azithromycin for Injection Aztreonam for Injection B Bacitracin for Injection Bacteriostatic Sodium Chloride Injection Bacteriostatic Water for Injection (WFI), Sterile Benztropine Mesylate Injection Benzylpenicilloyl Polylysine Injection Betamethasone Acetateand Betametthasone Sodium Phosphate injectable Suspension Betamethasone Sodium Phosphate 0.33 EU / mg EU / mg meq Cl 0.4 EU / mg EU / mg 0.17 EU / (1 mg of mix of amp and sulb and 0.33 mg, respectively) EU / mg 0.14 unit EU / mg 33.3 EU / mg 5.56 EU / mg 55.6 EU / mg of azathioprine 7.14 EU / mg 0.17 EU / mg if labeled sterile or processed into injectable 0.01 EU / Bacitracin unit if labeled sterile or processed into injectable 1 EU / ml 55.6 EU / mg 5833 EU / ml 29.2 EU / mg 29.2 EU / mg Betamethasone 2

3 Bethanechol Chloride Injection 2 Biperiden Lactate Injection 83.3 EU / mg Bleomycin for Injection 10 EU / Bleomycin Unit Bretylium Tosylate in Dextrose Injection Bretylium Tosylate Bretylium Tosylate Injection Brompheniramine Maleate Injection 35.7 EU / mg Bumetanide Injection 350 EU / mg Bupivacaine Hydrochloride and Epinephrine Injection 1.6 EU / mg Bupivacine Hydrochloride Bupivacaine Hydrochloride and Dextrose 1.8 EU / mg Bupivacine Hydrochloride Bupivacaine Hydrochloride Injection 2. Butorphanol Tartrate Injection 88 EU / mg C Caffeine and Sodium Benzoate Injection Caffeine Citrated 0.2 Calcitonin - Salmon unit Calcitriol Injection 100 EU / µg Calcium Chloride Calcium Gluceptate Injection 0.32 EU / mg Calcium Gluconate 0.17 EU / mg Calcium Levulinate Injection 35.7 EU / mg Capreomycin for Injection 0.3 Carbenicillin for Injection 0.0 Carboplatin for Injection 0.54 EU / mg Carboprost Tromethamine EU / mg Carmustine for Injection 0.9 Cefamandole Nafate for Injection 0.1 Cefamandole Cefazolin Injection 0.1 Cefepime for Injection 0.06 EU / mg Cefepime Hydrochloride 0.04 EU / mg if labeled sterile or processed into injectable Cefmetazole for Injection Cefonicid for Injection 0.3 Cefoperazone Injection Ceforanide 0.2 if labeled sterile or processed into injectable Cefotaxime Sodium for Injection Cefotetan for Injection 0.17 EU / mg if labeled sterile or processed into injectable Cefoxitin for Injection 0.13 EU / mg Ceftazidime 0. if labeled sterile or processed into injectable Ceftizoxime for Injection 0. Ceftriaxone Injection Cefuroxime for Injection 0. Cephalothin for Injection 0.13 EU / mg Cephapirin for Injection 0.17 EU / mg Cephradine for Injection Chloramphenicol Sodium Succinate of Chloramphenicol if labeled sterile or processed into injectable Chlordiazepoxide Hydrochloride 3.57 EU / mg Chloroquine Hydrochloride Injection Chlorothiazide Sodium 0.3 EU / mg Chlorpheniramine Maleate 8.8 EU / mg Chlorpromazine Hydrochloride 6.9 EU / mg Chorionic Gonadotropin 0.03 EU / USP Chorionic Gonadotropin Unit 3

4 Chromate Sodium Cr5l Injection Chromic Chloride Injection 16.7 EU / µg of chromium Chromic Phosphate P 32 Suspension Chromium Cr 51 Edetate Injection Cilastatin Sodium 0.17 EU / mg of cilastatin if labeled sterile Cimetidine Injection Ciprofloxacin for Injection Cisplatin for Injection 2 EU / mg Citric Acid, Magnesium Oxide and Sodium Carbinate Irrigation 2.8 EU / ml Clavulanate Potassium 0.03 EU / mg if labeled sterile or processed into injectable Clindamycin for Injection 0.58 EU / mg Cloprostenol Injection 2500 EU / mg Codeine Phosphate Injection 5.8 EU / mg Colchicine Injection EU / mg Colistimethate for Injection 2 EU / mg if labeled sterile or processed into injectable Corticotropin Injection 3.1 EU / USP Corticotropin Unit Cupric Chloride Injection 250 EU / mg of copper Cupric Sulfate Injection 250 EU / mg of copper Cyanocobalamine Injection 0.4 EU / µg Cyclophosphamide for Injection Cyclosporine Injection 0.84 EU / mg (use 1:10 dilution; mix 0.1 ml with 0.1 ml LAL reagent on vortex mixer for 5 seconds) Cysteine Hydrochloride for Injection Cytarabine for Injection 0.07 EU / mg if labeled sterile or processed into injectable D Dacarbazine for Injection 0.52 EU / mg Dactinomycin for Injection 100 EU / mg Dantrolene Sodium Daunorubicin Hydrochloride for Injection 4.3 EU / mg of Daunorubicin Deferoxamine Mesylate for Injection 0.33 EU / mg if labeled sterile or processed into injectable Desmopressin Acetate 10 EU / µg Desoxycorticosterone Acetate 71.4 EU / mg Desoxycorticosterone Pivalate Suspension 2.78 EU / mg Dexamethasone Acetate Injectable Suspension 21.7 EU / mg Dexamethasone Injection 2 Dexamethasone Sodium Phosphate Injection 31.3 EU / mg Dextran 1 25 EU / g Dextran 40 in Dextrose Injection 1 EU / ml Dextran 40 in Sodium Chloride Injection 1 EU / ml Dextran 70 in Dextrose Injection Dextran 70 in Sodium Chloride Injection Dextrose (<5%) Injection for injections containing less than 5% of Dextrose Dextrose (5-70%) Injection 10 EU / g for injections containing less than 5% and 70% of Dextrose Dextrose and Sodium Chloride Injection 10 EU / g Diatrizoate Meglumine and Diatrizoate Sodium 34.3%-35% 1.8 EU / ml Diatrizoate Meglumine and Diatrizoate Sodium 28.5%-29.1% 1.8 EU / ml Diatrizoate Meglumine and Diatrizoate Sodium 50%-25% 1.8 EU / ml Diatrizoate Meglumine and Diatrizoate Sodium 52%-8% 1.8 EU / ml Diatrizoate Meglumine and Diatrizoate Sodium 60%-30% 3.6 EU / ml Diatrizoate Meglumine and Diatrizoate Sodium 66%-10% 3.6 EU / ml Diatrizoate Meglumine Injection <50% 1.1 EU / ml for injections containing less than 50% Diatrizoate Meglumine 4

5 Diatrizoate Meglumine Injection > or equal to 50% Diatrizoate Sodium 20% Diatrizoate Sodium 25% Diatrizoate Sodium 50% Diazepam Injection Diazoxide Injection Dibucaine Hydrochloride Injection Dicyclomine Hydrochloridel Injection Diethylstilbestrol Injection Digitoxin Injection Digoxin Injection Dihydroergotamine Mesylate Injection Dihydrostreptomycin Injection Dimercaprol Dimethyl Sulfoxide Irrigation Dinoprost Tromethamine Diphenhydramine Hydrochloride Injection Dipyridamole Injection Dobutamine for Injection Dobutamine in Dextrose Injection Docetaxel Dolasetron Mesylate Injection Dopamine Hydrochloride Dopamine Hydrochloride in Dextrose Doxapram Hydrochloride Injection Doxorubicin Hydrochloride for Injection Doxycycline for Injection Doxycycline Hyclate Droperidol Dyphylline Injection E Edetate Calcium Disodium Injection Edetate Disodium Injection Edrophonium Chloride Injection Electrolytes Multiple and Dextrose Type 1,2,3,4 Electrolytes, Multiple, Type 1 & 2 Emetine Hydrochloride Enalaprilat Enoxaparin Sodium Injection Ephedrine Sulfate Injection Epinephrine Injection Epirubicin Hydrochloride Ergonovine Maleate Injection Ergotamine Tartrate Injection Erythromycin Gluceptate/Lactobionate Estradiol Injectable Suspension Estrone Injectable Suspension Ethacrynate Sodium Etoposide Injection 5 EU / ml for injections containing less than 50% Diatrizoate Meglumine 5.6 EU / ml for injections containing 20% of Diatrizoate Sodium 1.3 EU / ml for injections containing 25% of Diatrizoate Sodium 5 EU / ml for injections containing 50% of Diatrizoate Sodium 11.6 EU / mg 35.7 EU / mg 17.2 EU / mg EU / mg 17 8 EU / mg 3.4 EU / mg 8.8 EU / mg 5.56 EU / mg 5.56 EU / mg Doputamine 0.3 EU / mg 2.7 EU / mg EU / mg of Doputamine Hydrochloride EU / mg 3.3 EU / mg 2.2 EU / mg (from prepared 1.1 mg / ml DoxorubicinHydrochloride) 1.14 EU / mg 1.14 EU / mg (See Doxycycline for Injection) 35.7 EU / mg EU / mg 5.4 EU / mg 280 EU / mg 0.01 unit 1.7 EU / mg 357 EU / mg EU / mg 357 EU / mg 250 EU / mg 88 EU / mg 2 EU / mg (for a concentration of 0.31 mg Etoposide activity per ml) 5

6 F Famotidine EU / mg Fenoldopam Mesylate Injection 84 EU / mg Fentanyl Citrate 50 EU / mg Ferrous Citrate Fe 59 Injection 50 EU / ml Ferumoxides Injection 12.5 EU / ml Fludarabine Phosphate for Injection 7.7 EU / mg Fludeoxyglucose F 18 Injection Flumazenil C 11 Injection 100 EU / mg () Flunixin Meglumine Injection 4.54 EU / mg Fluorouracil Injection 0.33 EU / mg Fluphenazine Hydrochloride EU / mg Folic Acid Injection 357. Fructose Fructose and Sodium Chloride Furosemide Injection 3.6 EU / mg G Gadodiamide Injection EU / mg Gadopentetate Dimeglumine Injection 25 EU / ml Gadoteridol Injection 8.3 EU / ml Gallamine Triethiodide Gallium Citrate Ga 67 Injection Gentamicin Injection 0.7 Glycine Irrigation Glycopyrrolate 555. Gonadorelin Hydrochloride 3.6 EU / µg Guaifenesin for Injection 0.0 H Haloperidol Injection 71.4 EU / mg Heparin Lock Flush Solution Heparin Sodium Injection 0.03 EU / USP Heparin Unit Histamine Phosphate Injection 12 Hyaluronidase for Injection 2.3 EU / USP Hyalurondase Unit Hyaluronidase Injection 2.3 EU / USP Hyalurondase Unit Hydralazine Hydrochloride Injection 1.4 Hydrocortisone Injectable Suspension 1.2 Hydrocortisone Sodium Phosphate 1.2 of Hydrocortisine Hydrocortisone Sodium Succinate 1.2 of Hydrocortisine Hydromorphone Hydrochloride Injection 88 EU / mg Hydroxocobalamin 0.4 EU / µg Hydroxyzine Hydrochloride Injection 3.6 EU / mg Hyoscyamine Sulfate EU / mg I Idarubicin Hydrochloride for Injection 8.9 EU / mg Idarubicin Hydrochloride solution at 0.07 mg / ml Ifosfamide for Injection 0.12 Imipenem 0.17 EU / mg if labeled sterile Imipenem and Cilastatin for Injectable Suspension 0.23 EU / mg of Imipenem and 0.23 EU / mg Cilastatin Imipramine Hydrochloride Injection 6

7 Inamrinone Injection Indigotindisulfonate Sodium Injection Indium Chlorides In 113 m Injection Indium In 111 Capromab Pendetide Injection Indium In 111 Chloride Solution Indium In 111 Pentetreotide Injection Indium In 111 Satumomab Pendetide Injection Indium Pentetate In 111 Injection Indocyanine Green for Injection Indomethacin for Injection Insulin Human Insulin Human Injection Insulin Injection Insulin Isophane Suspension Insulin Lispro Injection Insulin Zinc Suspension (Ext. & Prompt) Inulin in Sodium Chloride Injection Iodide Sodium I 123 Injection Iodide Sodium I 125 Solution Iodide Sodium I 131 Solution Iodipamide Meglumine Injection Iodixanol Injection Iohexol Injection Iophendylate Injection Iopromide Injection Iothalamate Meglumine and Iothalamate Sodium (66.8%) Iothalamate Meglumine and Iothalamate Sodium (52%-26%) Iothalamate Meglumine Injection (43%) Iothalamate Sodium Injection Ioversol Injection Ioxilan Injection Iron Dextran Injection Iron Sorbitex Iron Sucrose Injection Isoflupredone Acetate Injecion Suspension Isoniazid Isoproterenol Hydrochloride Injection Isoxsuprine Hydrochloride Injection K Kanamycin Injection Ketamine Hydrochloride Ketorolac Tromethamine Injection Labetalol Hydrochloride Leucovorin Calcium Injection Leuprolide Acetate Levocarnitine Injection Levorphanol Tartrate Injection Lidocaine Hydrochloride and Dextrose Injection Lidocaine Hydrochloride and Epinephrine Injection Lidocaine Hydrochloride Injection EU / mg of Indomethacin at 1.0 mg / ml 10 EU / mg 0.8 EU / unit 0.8 EU / unit 0.8 EU / unit 0.8 EU / unit 0.8 EU / unit 0. of Inulin 3.6 EU / ml 0.2 EU / 50mg of Iodine 0.2 EU / 50mg of Iodine 0.6 EU / mg 1.25 EU / ml 3.35 EU / ml 3.35 EU / ml 0.9 EU / ml 3.35 EU / ml 1.4 EU / ml 0.2 EU / 50mg of Iodine of Iron 10 EU / ml 3.7 EU / mg of Iron 12 of Isoflupredone Acetate 0.3 EU / mg of Isoniazid 1250 EU / mg of Isoproterenol Hydrochloride 35.7 EU / mg 0.67 EU / mg 0.4 EU / mg 5.8 EU / mg 1.2 EU / mg EU / mg of Lidocaine Hydrochloride of Lidocaine Hydrochloride 1. 7

8 Lincomycin Injection of Lincomycin Lorazepam 100 EU / mg M Magnesium Sulfate 0.09 EU / mg Magnesium Sulfate in Dextrose Injection EU / mg Mangafodipir Trisodium 0.66 EU / mg Manganese Chloride Injection 0.45 EU / µg of Manganese Manganese Sulfate Injection 0.45 EU / µg of Manganese Mannitol in Sodium Chloride Injection 0.04 EU / mg of Manitol Mannitol Injection (< = 10%) 0.04 EU / mg for injections containing 10% or less Manitol Mannitol Injection (> 10%) 2.5 EU / g for injections containing greater than 10% Manitol Mechlorethamine Hydrochloride for Injection 12. Menadiol Sodium Diphosphate (K-4) 2 Menadione 58.3 EU / mg Menotropins for Injection 2.5 USP Follicle Stimulating Hormone Unit Meperidine Hydrochloride Injection 2.4 EU / mg Mepivacaine Hydrochloride and Levonordefrin Injection 0.8 EU / mg of Mepivacaine Hydrochloride Mepivacaine Hydrochloride Injection 0.8 EU / mg Meropenem for Injection 0.12 Mesoridazine Besylate Injection 7 EU / mg Metaraminol Bitartrate 3. Methadone Hydrochloride 8.8 EU / mg Methocarbamol Injection Methohexital Sodium Methotrexate Sodium Injection 0.4 EU / mg Methotrimerprazine 17.9 EU / mg Methyldopate Hydrochloride Methylene Blue Injection 2.5 EU / ml Methylergonovine Maleate 1.7 EU / µg Methylprednisolone Sodium Succinate Injection 0.17 EU / mg of Methylprednisolone Metoclopramide 2. Metoprolol Tartrate 2 Metronidazole Hydrochloride 0.3 Mezlocillin for Injection 0.06 EU / mg of Mezlocillin Miconazole Injection 0. Midazolam Hydrochloride 8.33 EU / mg Minocycline for Injection 1.2 Mitomycin for Injection 10 EU / mg Mitoxantrone Injection Morphine Sulfate Injection 17 EU / mg for Parenterals N Nafcillin Injection 0.13 EU / mg Nalorphine Hydrochloride 11.6 EU / mg Naloxone Hydrochloride Injection 500 EU / mg Neomycin for Injection 1.3 EU / mg Netilmicin 1.2 Niacin 3. Niacinamide Injection 3. Nitroglycerin 0.1 EU / µg 8

9 Norepinephrine Bitartrate Injection O Ondansetron Injection Orphenadrine Citrate Injection Oxacillin for Injection Oxymorphone Hydrochloride Oxytetracycline for Injection Oxytocin Injection P Paclitaxel Paclitaxel Injection Papaverine Hydrochloride Pen G Proc, D-Streptomycin, Prednisolone Pen G Proc, D-Streptomycin,Dexamethasone Penicillin G Benzathine Suspension Penicillin G Potassium for Injection Penicillin G Procaine Suspension (all) Penicillin G Sodium for Injection Pentazocine Injection Pentobarbital Sodium Injection Perflutren Protein-Type A Micro. Injection Perphenazine Phenobarbital Sodium for Injection Phenylbutazone Injection Phenylephrine Hydrochloride Injection Phenytoin Sodium Injection Physostigmine Salicylate Phytonadione Injection Piperacillin for Injection Plicamycin for Injection Potassium Acetate Injection Potassium Chloride for Injection Potassium Phosphate Injection Pralidoxine Chloride for Injection Prednisolone Sodium Phosphate Injection Prednisolone Sodium Succinate Injection Prednisolone Tebutate Suspension Prednisone Injectable Suspension Prilocaine Hydrochloride Prilocaine Hydrochloride and Epinephrine Procainamide Hydrochloride Injection Procaine Hydrochloride Procaine Hydrochloride and Epinephrine Procaine, Tetracaine and Levonordefrin Injection Prochlorperazine Edisylate Injection Promazine Hydrochloride Injection Prompt Insulin Zinc Suspension Propofol Propoxycaine, Procaine Hydrochloride and Norepinephrine Bitartrate 83.4 EU / mg of Norepinephrine 9.9 EU / mg 5.8 EU / mg EU / mg 35.7 unit 0.4 EU / mg 0.67 EU / mg 2.9 EU / mg unit unit unit unit unit unit 5.8 EU / mg 0.8 EU / mg 35.7 EU / mg 0.3 EU / mg EU / mg 83.4 EU / mg 14 EU / mg 0.07 EU / mg if sterile or processed into injectable 100 EU / mg 8.8 meq 8.8 meq if sterile or processed into injectable 5.8 EU / mg of Prednisolone 8.8 EU / mg 2.27 EU / mg 0.9 EU / mg 0.9 EU / mg EU / mg if labeled sterile or processed into injectable 0.6 EU / mg 0.6 EU / mg 17.9 EU / mg 1.8 EU / mg 0.8 unit 0.33 EU / mg 0.8 EU / mg of Propoxycaine Hydrochloride 9

10 Propoxycaine, Procaine Hydrochloride and Levonordefrin 0.8 EU / mg of Propoxycaine Hydrochloride Propranolol Hydrochloride Injection 55.6 EU / mg Protamine Sulfate Injection 7 EU / mg Protein Hydrolysate Injection Pyridostigmine Bromide Injection 17 EU / mg Pyridoxine Hydrochloride 0.4 EU / mg Q Quinidine Gluconate Injection 0.6 EU / mg R Ranitidine Injection 7 EU / mg Reserpine Injection 71. Riboflavin Injection 7. Rifampin for Injection Ringer's - Lactated in Dextrose Ringer's - Lactated Injection Ringer's in Dextrose Ringer's Injection Ringer's Irrigation Ritodrine Hydrochloride Injection Rubidium Chloride Rb82 Injection S Samarium Sm 153 Lexidronam Injection Sargramostim for Injection 50 EU / mg Scopolamine HBr Injection 55 Secobarbital Sodium Injection 0.9 EU / mg if labeled sterile or processed into injectable Selenious Acid (Selenium) 3.5 EU / µg Sincalide for Injection 83.3 EU / µg Sisomicin Sulfate Sodium Acetate Injection 3.9 meq Sodium Bicarbonate 5 meq Sodium Chloride Injection ( %) (labeled amount of sodium chloride is 0.5% - 0.9%) Sodium Chloride Injection (3-24.3%) 3.6 EU / ml (labeled amount of sodium chloride is 3.0% %) Sodium Chloride Irrigation Sodium Chromate Cr 51 Injection Sodium Fluoride F 18 Injection Sodium Iodide I 123 Solution Sodium Iodide I 131 Solution Sodium Lactate Injection 2 meq Sodium Nitoprusside for Injection 0.05 EU / µg if labeled sterile or processed into injectable Sodium Nitrite Injection 0.33 EU / mg Sodium Phosphate Injection 1. Sodium Phosphate P 32 Solution Sodium Thiosulfate 0.03 EU / mg Somtropin for Injection 20 EU / mg Spectinomycin Hydrochloride 0.09 EU / mg of Spectinomycin if labeled sterile or processed into injectable Sterile Vancomycin Hydrochloride 0.33 EU / mg of Vancomycin Streptomycin Injection 0.2 Strontium Chloride Sr89 Injection Succinylcholine Chloride for Injection 2 EU / mg if labeled sterile or processed into injectable 10

11 Sufentanil Citrate Sulbactam Sodium Sulfadiazine Sodium T Technetium Tc 99 m (Pyro, trimeta) Phosph Technetium Tc 99 m Albumin Aggregated Injection Technetium Tc 99 m Apcitide Injection Technetium Tc 99 m Arcitumomab Injection Technetium Tc 99 m Bicisate Injection Technetium Tc 99 m Depreotide Injection Technetium Tc 99 m Disofenin Technetium Tc 99 m Etidronate Technetium Tc 99 m Exametazime Injection Technetium Tc 99 m Gluceptate Technetium Tc 99 m Lidofenin TechnetiumTc 99 m Medronate Technetium Tc 99 m Mertiatide Injection Technetium Tc 99 m Nofetumomab Merpentan Injection Technetium Tc 99 m Oxidronate Technetium Tc 99 m Pentetate Injection Technetium Tc 99 m Pyrophosphate Technetium Tc 99 m Red Blood Cells Injection Technetium Tc 99 m Sestamibi Injection Technetium Tc 99 m Sodium Pertechnetate Technetium Tc 99 m Succimer Technetium Tc 99 m Sulfur Colloid Technetium Tc 99 m Tetrofosmin Injection Terbutaline Sulfate Injection Testosterone Injectable Suspension Tetracaine Hydrochloride and Dextrose (Intrathecal) Tetracaine Hydrochloride (Intrathecal) Tetracycline Hydrochloride Thallus Chloride Tl201 Injection Theophylline in Dextrose Injection Thiamine Hydrochloride Thiamylal Sodium Thiopental Sodium for Injection Thiotepa for Injection Thiothixene Hydrochloride for Injection Ticarcillin Disodium and Clavulanate Ticarcillin for Injection Tiletamine and Zolazepam for Injection Tilmicosin Injection Tobramycin for Injection Tobramycin Inhalation Solution Tolazoline Hydrochloride Injection Tolbutamide for Injection Triamcinolone Acetonide Injection Suspension Triamcinolone Diacetate Injection Suspension Triamcinolone Hexacetonide Suspension EU / mg of Sulbactum if labeled sterile of processed into injectable 0. 1,250 EU / mg 3. if labeled sterile or processed into injectable EU / mg 0.07 EU / mg EU / mg of combined Tiletamine and Zolazepam 2 EU / mg 60 EU / ml 0.8 EU / mg EU / mg EU / mg 11

12 Trifluoperazine Hydrochloride Injection Triflupromazine Hydrochloride Injection Trimethobenzamide Hydrochloride Tripelennamine Hydrochloride Injection Tromethamine Tubocurarine Chloride Injection U Urea for Injection V Valrubicin Intravesical Injection Vancomycin Injection Vasopressin Injection Vecuronium Bromide Verapamil Hydrochloride Vidarabine for Injection Vinblastine Sulfate for Injection Vincristine Sulfate for Injection Vincristine Sulfate Injection W Warfarin Sodium for Injection Water for Inhalation (Sterile) Water for Injection and Sterile WFI Water for Irrigation (Sterile) Water 15 O Injection X Xenon Xe133 Injection Xylazine Injection Y Yohimbine Injection Yttrium Y 90 Ibritumomab Tiuxetan Injection Z Zidovudine Injection Zinc Chloride Injection Zinc Sulfate Injection Zolazepam Hydrochloride 172 EU / mg 5.8 EU / mg 1.8 EU / mg 4.6 EU / mg 0.03 EU / mg 10 EU / mg EU / mg 0.14 EU / mg of Valrubicin 0.33 EU / mg 17 EU / Vasopressin Unit 10 EU / mg 16.7 EU / mg of Valrubicin except when used in opthalmic dosage 10 EU / mg 100 EU / mg EU / mg 0.25 EU / ml 0.25 EU / ml 1.7 EU / ml Zn 2 Zn 0.07 EU / mg Zolazepam 12

13 Contact Information North America Customer Service: (toll free) Scientific Support: (toll free) Europe Customer Service: Scientific Support: International Contact your local Lonza distributor Customer Service: Lonza Walkersville, Inc. Walkersville, MD Unless otherwise noted, all trademarks herein are marks of the Lonza Group or its affiliates. The information contained herein is believed to be correct and corresponds to the state of scientific and technical knowledge as of the date set forth above. However, no warranty is made, either expressed or implied, regarding its accuracy or the results to be obtained from the use of such information and no warranty is expressed or implied concerning the use of this information. The user assumes all risks of use. Any user must make his own determination and satisfy himself that the information supplied by Lonza and any recommendations given by Lonza are (i) suitable for intended process or purpose and (ii) in compliance with environmental, health and safety regulations. No statement is intended or should be construed as a recommendation to infringe any existing patent. Copyright 2012, Lonza Walkersville, Inc. All rights reserved. EM-USPCI 04/12 RT-LI004

GOBIERNO DE PUERTO RICO Administración de Servicios Médicos de Puerto Rico

GOBIERNO DE PUERTO RICO Administración de Servicios Médicos de Puerto Rico 1 Acetylcysteine Solution 20% Vial 10ml 2 Acetylcysteine Solution 20% Vial 30ml 3 Activated Charcoal Bottle 4 fl oz or 8 fl oz 4 Adenosine 6mg/2ml Inj Solution Syringe / Vial 2ml 5 Albuterol Sulfate Inhalation