SMART WORKFLOW SOLUTIONS Introducing DxM MicroScan WalkAway System* ...

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1 SMART WORKFLOW SOLUTIONS Introducing DxM MicroScan WalkAway System* The next-generation MicroScan WalkAway System combines proven technology and reliability with enhanced ease-of-use features to streamline workflows and improve productivity.... Continuous reagent monitoring technology provides enhanced liquid level sensing Easy-to-view external LED indicators show status at a glance Quick bottle release simplifies reagent maintenance Integrated reliability improvements maximize uptime * In development, pending CE compliance; not available for in vitro diagnostic use. Please contact your sales representative for more information.

2 COMING SOON FROM BECKMAN COULTER New MicroScan Gram-negative and Gram-positive panels* Beckman Coulter is pleased to announce the upcoming launch of 11 new Gram-negative and Gram-positive MicroScan panels. These include 7 new MicroScan MIC-only panels that provide extended ranges of antibiotic concentrations to assist in detection of antimicrobial resistance (AMR). MIC-only formats support laboratories utilizing alternative identification methods. Accurate MIC results in routine testing helps physicians choose and adapt patient therapies. This launch also includes new expert rules that align with the latest EUCAST and CLSI guidelines. Please contact your Sales Representative for additional information. Features and Benefits: Gram-negative panels 1. Lower dilutions of carbapenems, including EUCAST producing Enterobacteriaceae 2. Lower dilutions of levofloxacin and ciprofloxacin to detect fluoroquinolone resistance and to conform to new EUCAST breakpoints 3. Longer and lower dilutions of cefotaxime and ceftazidime both with and without clavulanic acid for detection and confirmation of ESBLs 4. Addition of trimethoprim 2-4 μg/ml to support EUCAST reporting guidelines Gram-positive panels 1. reporting for MRSA, MSSA, S. epidermidis and vancomycin-susceptible E. faecalis 2. Lower dilutions of ceftaroline and clindamycin for detection of emerging resistance 3. Lower dilutions of moxifloxacin to detect fluoroquinolone resistance and to conform to new EUCAST breakpoints 4. New formats designed specifically for testing of Staphylococci and Enterococci, maximizing antimicrobial agents reported by organism group 5. New formats maximize antimicrobial agents reported between the organism groups Enterobacteriaceae and nonfermentative Gram-negative bacilli 6. Updated Gram-negative identification database, including improved turnaround time for the identification of Acinetobacter Count on MicroScan for unmatched experience, expertise and selection. For over 35 years, MicroScan panels have provided gold-standard bacterial identification and susceptibility products to confront emerging resistance head on. MicroScan provides first-time accuracy with direct minimum inhibitory concentration (MIC) for trusted detection of emerging and critical antimicrobial resistance, helping you avoid delays associated with extra confirmatory testing, and real-time alerts to enable immediate action. * in development, pending CE compliance; not available for in vitro diagnostic use. Please contact your sales representative for more information.

3 NEW MICROSCAN GRAM-NEGATIVE MIC PANELS* Panel name EN 47 NF 50 EN 51 EN 52 MicroScan catalog number B B B B Reporting therapy CLSI CLSI or EUCAST EUCAST EUCAST Languages IT, Abbr. Antimicrobial agent µg/ml µg/ml µg/ml µg/ml Ak Amikacin Aug Amoxicillin/K Clavulanate 8/4-16/8-2/1-8/4 4/2-32/16 Am Ampicillin A/S Ampicillin/Sulbactam - 4/2-16/8 - - Azt Aztreonam Cpe Cefepime Cfe Cefixime Cft Cefotaxime Cft/CA Cefotaxime/K Clavulanate 0.5/4-4/4-0.5/4-8/4 0.5/4-4/4 Cfx Cefoxitin Cpd Cefpodoxime Caz Ceftazidime Caz/CA Ceftazidime/K Clavulanate 0.25/4-4/4-0.25/4-8/4 0.25/4-4/4 Cax Ceftriaxone Crm Cefuroxime C Chloramphenicol Cp Ciprofloxacin 0.12, Cl Colistin Dox Doxycycline Etp Ertapenem , Fos Fosfomycin Gm Gentamicin Imp Imipenem Lvx Levofloxacin 0.12, Mec Mecillinam , 8 Mer Meropenem , Min Minocycline NA Nalidixic Acid Nt Netilmicin Fd Nitrofurantoin Nxn Norfloxacin Ofl Ofloxacin Pi Piperacillin 8-16, P/T Piperacillin/Tazobactam 8/4-16/4, 64/4 8/4-64/4 4/4-16/4 4/4-16/4 Te Tetracycline Ti Ticarcillin Tim Ticarcillin/K Clavulanate - 16/2-64/2 - - Tgc Tigecycline To Tobramycin T Trimethoprim T/S Trimethoprim/Sulfamethoxazole 2/38-4/76 1/19-4/76 2/38-4/76 2/38-4/76 * In development, pending CE compliance; not available for in vitro diagnostic use. Please contact your sales representative for more information.

4 NEW MICROSCAN GRAM-NEGATIVE COMBO PANELS* Panel name Neg/Urine Combo 81 Neg Combo 82 Neg Combo 83 Neg Breakpoint Combo 50 MicroScan catalog number B B B B Reporting therapy EUCAST EUCAST EUCAST CLSI Languages IT, IT, IT, IT, Abbr. Antimicrobial agent µg/ml µg/ml µg/ml µg/ml Ak Amikacin Aug Amoxicillin/K Clavulanate 8/4, 32/16 4/2-8/4 2/1, 8/4 8/4-16/8 Am Ampicillin , A/S Ampicillin/Sulbactam /4-16/8 Azt Aztreonam , Cfz Cefazolin Cpe Cefepime , Cfe Cefixime Cft Cefotaxime , , 16 Cft/CA Cefotaxime/K Clavulanate 0.5/4-1/4, 4/4 0.5/4-1/4, 4/4 0.5/4, 4/4 0.5/4, 4/4 Cfx Cefoxitin Caz Ceftazidime , 4-8 1, 4-16 Caz/CA Ceftazidime/K Clavulanate 0.25/4-0.5/4, 2/4 0.25/4, 2/4 0.25/4, 2/4 0.25/4, 2/4 Crm Cefuroxime C Chloramphenicol Cp Ciprofloxacin Cl Colistin Etp Ertapenem Fos Fosfomycin Gm Gentamicin Imp Imipenem Lvx Levofloxacin Mec Mecillinam Mer Meropenem , 2-8, , 2, Mxf Moxifloxacin NA Nalidixic Acid Fd Nitrofurantoin Nxn Norfloxacin Pi Piperacillin P/T Piperacillin/Tazobactam 8/4-16/4 8/4-16/4 4/4-16/4 16/4, 64/4 Te Tetracycline Ti Ticarcillin Tgc Tigecycline To Tobramycin T Trimethoprim T/S Trimethoprim/Sulfamethoxazole 2/38-4/76 2/38-4/76 2/38-4/76 2/38 * In development, pending CE compliance; not available for in vitro diagnostic use. Please contact your sales representative for more information.

5 NEW MICROSCAN GRAM-POSITIVE MIC PANELS* Panel name Pos MIC STA 35 Pos MIC STA 36 Pos MIC E 37 MicroScan cathalog number B B B Reporting therapy CLSI EUCAST CLSI or EUCAST Languages Abbr. Antimicrobial agent µg/ml µg/ml µg/ml Ak Amikacin Aug Amoxicillin/K Clavulanate 4/2-8/4-2/1-8/4 Am Ampicillin Azi Azithromycin CfxS Cefoxitin Screen Cpt Ceftaroline C Chloramphenicol Cp Ciprofloxacin Cd Clindamycin Dap Daptomycin E Erythromycin Fos Fosfomycin 4, FA Fusidic Acid 2, 16 2, 16 - Gm Gentamicin GmS Gentamicin Synergy Screen Imp Imipenem ICd Inducible Clindamycin Test 4/0.5 4/0.5 - K Kanamycin Lvx Levofloxacin Lin Lincomycin Lzd Linezolid Min Minocycline Mxf Moxifloxacin Mup Mupirocin 4-8, , Fd Nitrofurantoin Ofl Ofloxacin Ox Oxacillin P Penicillin 0.03, , Prs Pristinamycin Rif Rifampin StS Streptomycin Synergy Screen Syn Synercid Tei Teicoplanin Te Tetracycline Tgc Tigecycline To Tobramycin T/S Trimethoprim/Sulfamethoxazole 1/19-4/76 1/19-4/ /4.75-2/38 Va Vancomycin * In development, pending CE compliance; not available for in vitro diagnostic use. Please contact your sales representative for more information.

6 2017 Beckman Coulter, Inc. All rights reserved. Beckman Coulter, the stylized logo and the Beckman Coulter product and service marks mentioned herein are trademarks or registered trademarks of Beckman Coulter, Inc. in the United States and other countries. BR MULTI-EN

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