Practical Notes on Antibiotics
|
|
- Edmund Kelley
- 5 years ago
- Views:
Transcription
1 Practical Notes on Antibiotics 1. Gram +ve bacteria Streptococci Staphylococci Gram +ve 2. Gram ve bacteria E-Coli Pseudomonas Gram -ve 3. Atypical organisms Mycoplasma, Chalmydia Classification of bacteria Anti-Staph Anti-Pseudomonal Gram ve bacteria G-ve Gram +ve bacteria G+ve Penicillins 1. Natural penicillins 2. Penicillinase resistant penicillin 3. Broad-spectrum penicillins 4. Extended-spectrum penicillins
2 1. Natural Penicillins Only against G+ve (Narrow spectrum) NO Anti-staph effect (penicillinase sensitive) 1. Benzyl-penicillin (Short acting / Penicillin G) IV IM 1,000,000 Vial 2. Benzathine-penicillin (Long acting) IM 1,200,000 Vial Main indication Used mainly in prophylaxis against Rheumatic fever in children with streptococcal pharyngitis ESR or ASO titre Jones criteria
3 Main side effects 1. Severe pain at site of injection 3-5 Xylocaine Lidocaine 3 2. Serious allergic reaction 10 Intradermal Forearm 10 5 Blocked Retarpen vial 5 LE Pencitard vial 4 LE Depopen vial 5 LE Extencilline vial 40 LE
4 3. Penicillin V Main indication Oral form Drug of choice in streptococcal pharyngitis & tonsillitis Ospen 1 gm tab Ospen 1.5 gm tab Ospen susp. 2. Penicillinase resistant Penicillins 12 tab.. 5 LE 12 tab.. 10 LE 5.5 LE Narrow spectrum - Penicillinase Resistant Anti-Staph effect They include : Methicillins Cloxacillin Dicloxacillin Flucloxacillin in combination with Ampicillin & Amoxycillin Amoxycillin penicillinase-resistance Staph MRSA Methicillin-Resistant Staph. Aureus Hospital-acquired infections VRSA Methicillins Penicillins Vancomycin Vancomycin Staph infection
5 3. Broad-spectrum Penicillins Against G+ve & G-ve (Mainly on G+ve) NO Anti-staph effect (Penicillinase sensitive) except if combined with penicillinase-inhibitors They include : Ampicillin & Amoxycillins IM or IV Vials, Caps & Suspension Ampicillins : Ampicillin Epicocillin Amoxycillins : Emox Ibiamox Biomox - Amoxcil Resistance Combinations 4. Extended-spectrum Penicillins Penicillins Spectrum Combinations Broad-spectrum + Penicillinase inhibitor Resp.Tract infections - Otitis - sinusitis G+ve 1. Ampicillin + Penicillinase resistant penicillins o Ampicillin + Flucloxacillin Ampiflox 250 susp Ampiflox 250 & 500 caps 6 LE 4.5 & 6 LE o Ampicillin + Cloxacillin Ampiclox 250 susp Ampiclox 500 caps 6 LE 7 LE
6 2. Amoxycillin + Penicillinase resistant penicillins o Amoxycillin + Flucloxacillin Flumox 250 susp 250 & 500 caps o Amoxycillin + Dicloxacillin Amoclox 500 caps 13, 8, 18 LE 16 caps LE 3. Ampicillin + Penicillinase inhibitor (Sulbactam) o Unasyn Unasyn 750 mg, 1.5, 3 gm vial Unasyn 375 mg tab Unasyn 250 susp 12, 17, 24 LE 12 tab.. 40 LE 33 LE Unictam - Sulbin 4. Amoxycillin + Penicillinase inhibitor (Clavulanic acid) o Augmentin Augmentin 600 mg, 1.2 gm vial Augmentin 375, 625 mg, 1 gm tab Augmentin 156, 312, 457 susp 11.5, 20 LE 20, 35, 58 LE 18, 28, 37 LE Hibiotic Emoxclav Magnabiotic - Curam Amoclawin 5. Pipracillin + Penicillinase inhibitor (Tazobactam) Tazocin 2.25, 4.5 gm vial 40, 90 LE Anti-Pseudomonas Pipracillin
7 1. Allergic reaction 2. Antibiotic-induced diarrhea Ampicillin & Amoxycillin GIT inflammation due to eradication of normal bacterial flora Clostridium difficile Pseudo-membranous colitis Oral contraceptives Penicillin Antibiotic-induced diarrhea Penicillins Condom Back-up method Severe liver or kidney disease Penicillin 1. Tetracyclins Permanent discoloration of teeth 2. Fluroquinolones (e.g. Ciprofloxacin) Premature closure of epiphysis 3. Chloramphenicol Bone marrow depression Penicillins - Cephalosporins - Erythromycins
8 Cephalosporins 1. 1 st generation cephalosporins 1. Cephradine Mainly against G +ve Weak Anti-staph effect o Velosef Velosef 250, 500 caps Velosef 500 mg, 1 gm vial Velosef 125, 250 susp - 12 caps.. 7, 15 LE 5.5, 9.5 LE 4.5, 8.5 LE Farcosef Ultracef 2. Cephadroxil Strong Anti-staph Long duration of action Only Oral form (No parentral form) o Duricef Duricef 500 mg caps, 1 gm tab Duricef 125, 250, 500 susp 12, 12.5 LE 6.5, 12, 15 LE Biodroxil Ibidroxil Curosafe
9 3. Cephalexin o Ceporex Ceporex 500 mg, 1 gm vial Ceporex 250, 500 mg, 1 gm tab Ceporex 125, 250 susp - Cephalexin Ospexin 5, 8 LE 6.5, 15, 17 LE 6, 10 LE 2. 2 nd generation cephalosporins 1. Cefuroxime Zinnat Equally effective against G +ve & G -ve Weak Anti-staph effect Zinnat 750 mg, 1.5 gm vial Zinnat 250, 500 tab Zinnat 125 susp 18, 34 LE 10 tab.. 25, 45 LE 19 LE 2. Cefaclor Atypical Organisms o Bacticlor Bacticlor 250, 500 caps Bacticlor 125, 250 susp Parentral 12 cap.. 23, 33 LE 12, 23 LE Ceclor Cefaclor
10 3. 3 rd generation cephalosporins Mainly against G -ve Strong Anti-staph effect Strong Anti-pseudomonal effect esp. Ceftazidim Oral Ceftriaxone Injection 1. Cefotaxime o Claforan Claforan 250, 500 mg, 1 gm vial 9, 15, 26 LE Cefotax - Sigmataxim 2. Ceftriaxone Gastroenteritis esp.typhoid o Ceftriaxone Ceftriaxone 0.5, 1 gm vial Ceftriaxone 1 gm vial 15, 30 LE 11 LE Lidocaine Rociphen Wintriaxone
11 3. Cefoperazone Biliary tract infection Extensively excrted in bile Testicular atrophy o Cefobid Cefobid 0.5, 1, 2 gm vial 16, 28, 41 LE Cefazone Cefoperazone 4. Ceftazidime Strong Anti-Pseudomonas o Fortum Fortum 250, 500 mg, 1 gm vial 10, 15, 38 LE Cefidime - Ceftazidime 5. Cefdinir Oral o Cefdin Cefdin 125 susp Cefdin 300 caps 34 LE 10 caps.. 63 LE Dinar - Omnicef
12 6. Cefixime G+ve & G-ve Oral Spectrum Otitis media Sinusitis URTI - UTIs o Ximacef Ximacef 100, 200 susp 20, 32 LE Ximacef 200, 400 caps 8 caps.. 42 LE 5 caps.. 42 LE Suprax - Cefixime 4. 4 th generation cephalosporins (Cefipime) One of the Boradest spectrums among antibiotics o Maxipime Maxipime 0.5, 1 gm vial 22, 38 LE Cefrom Wincef - Forcetex
13 Fluro-Quinolones 1. Ciprofloxacine Effective against G +ve & G-ve Gastroenteriris & UTI o Ciprobay Ciprobay 250,500,750 tb 10 tab.. 26, 46, 65 LE Ciprofar Ciprocin Ciprofloxacin 2. Levofloxacin UTI o Tavanic Tavanic 500 tab Tavanic 500 vial 5 tab.. 85 LE 82 LE Tavacin 500, 750 tab Levoflox Levoxin Leeflox Alfacef 3. Moxifloxacin o Avalox Avalox 400 tab 5 tab.. 27, 28 LE 5 tab.. 90 LE Moxiflox Moflox (54 LE)
14 4. Ofloxacin o Tarivid Tarivid 200 tab 10 tab.. 39 LE Kiroll Tarivan 1. Qunolones & NSAIDS "DON'T MIX" Mixing Quinolones & NSAIDS risk of convulsions in epileptic patient NSAIDS Quinolones 2. Quinolones & Theophylline Narrow therapeutic window Theophylline Theophylline Theophylline Quinolones 3. Quinolones & Chronic kidney disease Quinolones 4. Quinolones & G6PD Deficiency "Favism" Hemolysis Analgesic : Paracetamol NSAIDS Antibiotic : Penicillins - Cephalosporins 1. Quinolones (e.g. Ciprofloxacin) 2. Sulphamethoxazol (e.g. Septazol, Septrin) 3. Nitrofurantoin (e.g. Uvamine retard)
15 Macrolides Mainly against G +ve Very Strong against Atypical micro-organisms Safe ORAL Penicillin allergy 1. Azithromycin Pharyngitis Atypical pneumonia o Zithromax Zithromax 250 caps Zithromax 600, 900, 1200 susp 6 caps.. 54 LE 26, 35, 44 LE Zithrocin 500 caps Zithrokan 500 caps (3 caps.. 18 LE) 2. Erythromycin o Erythrocin Erythrocin 250, 500 tab Erythrocin susp 12 tab.. 12 LE 10 tab.. 4 LE 7.5 LE Erythrin Erythromycin
16 3. Clarithromycin o Klacid Klacid 250, 500 tab Klacid 125, 250 susp 14 tab.. 45, 85 LE 18, 20 LE Claritho Claribiotic Aminoglycosides Mainly against G -ve Strong Anti-Pseudomonas effect Oral Side effects Nephrotoxic & Ototoxic 1. Gentamycin Most Nephrotoxic o Garamycin Garamycin 80,40,20 amp 3 amp..9 LE 6 amp.. 9, 6 LE Epigent Gentamycin
17 2. Amikacin Most Ototoxic o Amikin Amikin 100, 250, 500 vial 5, 8, 15 LE Amikacin vial Carbapenems Strong against G +ve & G-ve Broadest spectrum available in markets 1. Imipenem Tienam 0.5 gm vial 96 LE 2. Meropenem Meronem 0.5, 1 gm vial 80, 116 LE 3. Azteronem Azactam 0.5, 1 gm vial 18, 35 LE
18
Similar to Penicillins: -Chemically. -Mechanism of action. -Toxicity.
Similar to Penicillins: -Chemically. -Mechanism of action. -Toxicity. Cephalosporins are divided into Generations: -First generation have better activity against gram positive organisms. -Later compounds
More informationApproach to pediatric Antibiotics
Approach to pediatric Antibiotics Gassem Gohal FAAP FRCPC Assistant professor of Pediatrics objectives To be familiar with common pediatric antibiotics o Classification o Action o Adverse effect To discus
More informationß-lactams. Sub-families. Penicillins. Cephalosporins. Monobactams. Carbapenems
β-lactams ß-lactams Sub-families Penicillins Cephalosporins Monobactams Carbapenems ß-lactams Mode of action PBPs = Trans/Carboxy/Endo- peptidases PBP binding (Penicillin-Binding Proteins) activation of
More informationAntibiotic. Antibiotic Classes, Spectrum of Activity & Antibiotic Reporting
Antibiotic Antibiotic Classes, Spectrum of Activity & Antibiotic Reporting Any substance of natural, synthetic or semisynthetic origin which at low concentrations kills or inhibits the growth of bacteria
More information2015 Antibiotic Susceptibility Report
Citrobacter freundii Enterobacter aerogenes Enterobacter cloacae Escherichia coli Haemophilus influenzenza Klebsiella oxytoca Klebsiella pneumoniae Proteus mirabilis Pseudomonas aeruginosa Serratia marcescens
More information2016 Antibiotic Susceptibility Report
Fairview Northland Medical Center and Elk River, Milaca, Princeton and Zimmerman Clinics 2016 Antibiotic Susceptibility Report GRAM-NEGATIVE ORGANISMS 2016 Gram-Negative Non-Urine The number of isolates
More informationCell Wall Weakeners. Antimicrobials: Drugs that Weaken the Cell Wall. Bacterial Cell Wall. Bacterial Resistance to PCNs. PCN Classification
Cell Wall Weakeners Antimicrobials: Drugs that Weaken the Cell Wall Beta Lactams Penicillins Cephalosporins Carbapenems Aztreonam Vancomycin Teicoplanin Bacterial Cell Wall Bacterial cytoplasm is hypertonic
More informationNational Clinical Guideline Centre Pneumonia Diagnosis and management of community- and hospital-acquired pneumonia in adults
National Clinical Guideline Centre Antibiotic classifications Pneumonia Diagnosis and management of community- and hospital-acquired pneumonia in adults Clinical guideline 191 Appendix N 3 December 2014
More informationRational management of community acquired infections
Rational management of community acquired infections Dr Tanu Singhal MD, MSc Consultant Pediatrics and Infectious Disease Kokilaben Dhirubhai Ambani Hospital, Mumbai Why is rational management needed?
More informationTreatment of Respiratory Tract Infections Prof. Mohammad Alhumayyd Dr. Aliah Alshanwani
Treatment of Respiratory Tract Infections Prof. Mohammad Alhumayyd Dr. Aliah Alshanwani 30-1-2018 1 Objectives of the lecture At the end of lecture, the students should be able to understand the following:
More informationAdvanced Practice Education Associates. Antibiotics
Advanced Practice Education Associates Antibiotics Overview Difference between Gram Positive(+), Gram Negative(-) organisms Beta lactam ring, allergies Antimicrobial Spectra of Antibiotic Classes 78 Copyright
More informationnumber Done by Corrected by Doctor
number 28 Done by Dina Yaseen Corrected by حسام أبو عوض Doctor مالك الزحلف Cephalosporins -Cephalosporins are β-lactam antibiotics isolated from a strain of Streptomyces. -They are bactericidal and work
More informationThe β- Lactam Antibiotics. Munir Gharaibeh MD, PhD, MHPE School of Medicine, The University of Jordan November 2018
The β- Lactam Antibiotics Munir Gharaibeh MD, PhD, MHPE School of Medicine, The University of Jordan November 2018 Penicillins. Cephalosporins. Carbapenems. Monobactams. The β- Lactam Antibiotics 2 3 How
More informationnumber Done by Corrected by Doctor Dr.Malik
number 27 Done by Fatimah Farhan Corrected by Basil Al-Bakri Doctor Dr.Malik Note: anything in red is just extra info and you will not be asked about it in the exam. In this sheet we will continue talking
More informationPerichondritis: Source: UpToDate Ciprofloxacin 10 mg/kg/dose PO (max 500 mg/dose) BID Inpatient: Ceftazidime 50 mg/kg/dose q8 hours IV
Empiric Antibiotics for Pediatric Infections Seen in ED NOTE: Choice of empiric antibiotic therapy must take into account local pathogen frequency and resistance patterns, individual patient characteristics,
More information21 st Expert Committee on Selection and Use of Essential Medicines Peer Review Report Antibiotics Review
(1) Have all important studies/evidence of which you are aware been included in the application? Yes No Please provide brief comments on any relevant studies that have not been included: (2) For each of
More informationPharmacology Week 6 ANTIMICROBIAL AGENTS
Pharmacology Week 6 ANTIMICROBIAL AGENTS Mechanisms of antimicrobial action Mechanisms of antimicrobial action Bacteriostatic - Slow or stop bacterial growth, needs an immune system to finish off the microbe
More informationAminoglycosides. Spectrum includes many aerobic Gram-negative and some Gram-positive bacteria.
Aminoglycosides The only bactericidal protein synthesis inhibitors. They bind to the ribosomal 30S subunit. Inhibit initiation of peptide synthesis and cause misreading of the genetic code. Streptomycin
More informationSuggestions for appropriate agents to include in routine antimicrobial susceptibility testing
Suggestions for appropriate agents to include in routine antimicrobial susceptibility testing These suggestions are intended to indicate minimum sets of agents to test routinely in a diagnostic laboratory
More informationInteractive session: adapting to antibiogram. Thong Phe Heng Vengchhun Felix Leclerc Erika Vlieghe
Interactive session: adapting to antibiogram Thong Phe Heng Vengchhun Felix Leclerc Erika Vlieghe Case 1 63 y old woman Dx: urosepsis? After 2 d: intermediate result: Gram-negative bacilli Empiric antibiotic
More informationMEDICATIONS MEXICO S DE R.L. DE C.V. Agrifen Acetaminophen Chlorpheniramine 40 # Amikacin Generic 500 mg 2ml 2 ampoules #
Agrifen Acetaminophen Chlorpheniramine 40 $10 tabs Amikacin Generic 500 mg 2ml 2 ampoules $11 inyectable Amoxil Amoxicillin 500 mg 12 Caps $20 Amoxil Amoxicillin Generic 500 mg 12 Caps $13 Amoxil Amoxicillin
More informationCephalosporins, Quinolones and Co-amoxiclav Prescribing Audit
Cephalosporins, Quinolones and Co-amoxiclav Prescribing Audit Executive Summary Background Antibiotic resistance poses a significant threat to public health, as antibiotics underpin routine medical practice.
More informationnumber Done by Corrected by Doctor
number 32 Done by Nazek Hyasat Corrected by Doctor مالك الزحلف In this sheet we will talk about two cute drugs and a group of drugs, wish you a pleasant study... First of all, we will talk about clindamycin,which
More informationGENERAL NOTES: 2016 site of infection type of organism location of the patient
GENERAL NOTES: This is a summary of the antibiotic sensitivity profile of clinical isolates recovered at AIIMS Bhopal Hospital during the year 2016. However, for organisms in which < 30 isolates were recovered
More information** the doctor start the lecture with revising some information from the last one:
Page 1 of 7 ** the doctor start the lecture with revising some information from the last one: #penicillin G has a good susceptibility against gram(+ve), Neisseria (-ve) #mostly active against strep. (don
More informationEAGAR Importance Rating and Summary of Antibiotic Uses in Humans in Australia
EAGAR Importance Rating and Summary of Antibiotic Uses in Humans in Australia Background The Expert Advisory Group on Antimicrobial Resistance of the NH&MRC provides advice to Australian governments and
More informationAntimicrobial Update. Alison MacDonald Area Antimicrobial Pharmacist NHS Highland April 2018
Antimicrobial Update Alison MacDonald Area Antimicrobial Pharmacist NHS Highland alisonc.macdonald@nhs.net April 2018 Starter Questions Setting the scene... What if antibiotics were no longer effective?
More informationAntibiotics 1. Lecture 8
Antibiotics 1 Lecture 8 Overview of antibiotics What am I treating? Viral, bacterial, fungal, mycobacterial, etc. Who am I treating? Host factors: age, genetic factors, co-morbidities (renal and liver
More informationMedicinal Chemistry 561P. 2 st hour Examination. May 6, 2013 NAME: KEY. Good Luck!
Medicinal Chemistry 561P 2 st hour Examination May 6, 2013 NAME: KEY Good Luck! 2 MDCH 561P Exam 2 May 6, 2013 Name: KEY Grade: Fill in your scantron with the best choice for the questions below: 1. Which
More informationAntimicrobials. Antimicrobials
Antimicrobials For more than 50 years, antibiotics have come to the rescue by routinely producing rapid and long-lasting miracle cures. However, from the beginning antibiotics have selected for resistance
More informationJanuary 2014 Vol. 34 No. 1
January 2014 Vol. 34 No. 1. and Minimum Inhibitory Concentration (MIC) Interpretive Standards for Testing Conditions Medium: diffusion: Mueller-Hinton agar (MHA) Broth dilution: cation-adjusted Mueller-Hinton
More informationOther Beta - lactam Antibiotics
Other Beta - lactam Antibiotics Assistant Professor Dr. Naza M. Ali Lec 5 8 Nov 2017 Lecture outlines Other beta lactam antibiotics Other inhibitors of cell wall synthesis Other beta-lactam Antibiotics
More informationEUCAST recommended strains for internal quality control
EUCAST recommended strains for internal quality control Escherichia coli Pseudomonas aeruginosa Staphylococcus aureus Enterococcus faecalis Streptococcus pneumoniae Haemophilus influenzae ATCC 59 ATCC
More informationRoutine internal quality control as recommended by EUCAST Version 3.1, valid from
Routine internal quality control as recommended by EUCAST Version.1, valid from 01-01-01 Escherichia coli Pseudomonas aeruginosa Staphylococcus aureus Enterococcus faecalis Streptococcus pneumoniae Haemophilus
More informationa. 379 laboratories provided quantitative results, e.g (DD method) to 35.4% (MIC method) of all participants; see Table 2.
AND QUANTITATIVE PRECISION (SAMPLE UR-01, 2017) Background and Plan of Analysis Sample UR-01 (2017) was sent to API participants as a simulated urine culture for recognition of a significant pathogen colony
More informationChoosing the Best Antibiotic in Problem Outpatient Infectious Disease Cases
Choosing the Best Antibiotic in Problem Outpatient Infectious Disease Cases Dr. Earl Rubin Associate Professor Department of Pediatrics Division of Infectious Diseases Montreal Children s Hospital Disclosures
More informationجداول میکروارگانیسم های بیماریزای اولویت دار و آنتی بیوتیک های تعیین شده برای آزمایش تعیین حساسیت ضد میکروبی در برنامه مهار مقاومت میکروبی
جداول میکروارگانیسم های بیماریزای اولویت دار و آنتی بیوتیک های تعیین شده برای آزمایش تعیین حساسیت ضد میکروبی در برنامه مهار مقاومت میکروبی ویرایش دوم بر اساس ed., 2017 CLSI M100 27 th تابستان ۶۹۳۱ تهیه
More informationAntibacterial therapy 1. د. حامد الزعبي Dr Hamed Al-Zoubi
Antibacterial therapy 1 د. حامد الزعبي Dr Hamed Al-Zoubi ILOs Principles and terms Different categories of antibiotics Spectrum of activity and mechanism of action Resistancs Antibacterial therapy What
More informationAntibiotic Updates: Part II
Antibiotic Updates: Part II Fredrick M. Abrahamian, DO, FACEP, FIDSA Health Sciences Clinical Professor of Emergency Medicine David Geffen School of Medicine at UCLA Los Angeles, California Financial Disclosures
More informationMicrobiology : antimicrobial drugs. Sheet 11. Ali abualhija
Microbiology : antimicrobial drugs Sheet 11 Ali abualhija return to our topic antimicrobial drugs, we have finished major group of antimicrobial drugs which associated with inhibition of protein synthesis
More informationNational Clinical Guideline Centre Pneumonia Diagnosis and management of community- and hospital-acquired pneumonia in adults
National Clinical Guideline Centre Pneumonia Diagnosis and management of community- and hospital-acquired pneumonia in adults Clinical guideline 191 Appendix O 3 December 2014 Final version Commissioned
More informationMethicillin Resistant Staphylococcus Aureus (MRSA) Achievement in Al-Mafraq Hospital Abu Dhabi, UAE
Methicillin Resistant Staphylococcus Aureus (MRSA) Achievement in Al-Mafraq Hospital Abu Dhabi, UAE By: Mr. Moh d Hamad, Infection Control Officer, April, 2004 25% of the individuals are permanent carrier
More informationAntibiotic Abyss. Discussion Points. MRSA Treatment Guidelines
Antibiotic Abyss Fredrick M. Abrahamian, D.O., FACEP, FIDSA Professor of Medicine UCLA School of Medicine Director of Education Department of Emergency Medicine Olive View-UCLA Medical Center Sylmar, California
More informationRate In Rs.Ps (ED Included. Tax Extra) Sl No Name Of The Product Pack. Scheduled And Non-Scheduled Formulations Capsules
KAPL list of products applicable for Institutional/Hospital supplies under Pharmaceuticals Purchase Policy (PPP) issued by Department of Pharmaceuticals, Ministry of Chemicals & Fertilizers, Govt. of India
More informationHelp with moving disc diffusion methods from BSAC to EUCAST. Media BSAC EUCAST
Help with moving disc diffusion methods from BSAC to EUCAST This document sets out the main differences between the BSAC and EUCAST disc diffusion methods with specific emphasis on preparation prior to
More information2018 OPTIONS FOR INDIVIDUAL MEASURES: REGISTRY ONLY. MEASURE TYPE: Process
Quality ID #65 (NQF 0069): Appropriate Treatment for Children with Upper Respiratory Infection (URI) National Quality Strategy Domain: Efficiency and Cost Reduction 2018 OPTIONS FOR INDIVIDUAL MEASURES:
More informationAntimicrobial Susceptibility Testing: Advanced Course
Antimicrobial Susceptibility Testing: Advanced Course Cascade Reporting Cascade Reporting I. Selecting Antimicrobial Agents for Testing and Reporting Selection of the most appropriate antimicrobials to
More informationمادة االدوية المرحلة الثالثة م. غدير حاتم محمد
م. مادة االدوية المرحلة الثالثة م. غدير حاتم محمد 2017-2016 ANTIMICROBIAL DRUGS Antimicrobial drugs Lecture 2 The Action of Antimicrobial Drugs 1- Inhibitors of bacterial Cell Wall Synthesis. β-lactams(
More information11/10/2016. Skin and Soft Tissue Infections. Disclosures. Educational Need/Practice Gap. Objectives. Case #1
Disclosures Selecting Antimicrobials for Common Infections in Children FMR-Contemporary Pediatrics 11/2016 Sean McTigue, MD Assistant Professor of Pediatrics, Pediatric Infectious Diseases Medical Director
More informationAntibiotics (2): - Before you start: this lecture has a lot of names and things get entangled together, but I
Antibiotics (2): - Before you start: this lecture has a lot of names and things get entangled together, but I have nothing to do but to write everything the Doctor mentioned. I hope it will be clear. -
More information56 Clinical and Laboratory Standards Institute. All rights reserved.
Table 2C 56 Clinical and Laboratory Standards Institute. All rights reserved. Table 2C. Zone Diameter and Minimal Inhibitory Concentration Breakpoints for Testing Conditions Medium: Inoculum: diffusion:
More informationAntimicrobial Susceptibility Patterns
Antimicrobial Susceptibility Patterns KNH SURGERY Department Masika M.M. Department of Medical Microbiology, UoN Medicines & Therapeutics Committee, KNH Outline Methodology Overall KNH data Surgery department
More informationPrescribing Guidelines for Outpatient Antimicrobials in Otherwise Healthy Children
Prescribing Guidelines for Outpatient Antimicrobials in Otherwise Healthy Children Prescribing Antimicrobials for Common Illnesses When treating common illnesses such as ear infections and strep throat,
More informationSupplementary Online Content
Supplementary Online Content Gerber JS, Prasad PA, Fiks AG, et al. Effect of an outpatient antimicrobial stewardship intervention on broad-spectrum antibiotic prescribing by primary care pediatricians:
More informationAntibiotic Guidelines
Antibiotic Guidelines Antibiotics were first discovered in the middle of the 20 th century and have since saved millions of lives and practically eradicated previously fatal conditions such as tuberculosis
More informationMicrobiology ( Bacteriology) sheet # 7
Microbiology ( Bacteriology) sheet # 7 Revision of last lecture : Each type of antimicrobial drug normally targets a specific structure or component of the bacterial cell eg:( cell wall, cell membrane,
More information2019 COLLECTION TYPE: MIPS CLINICAL QUALITY MEASURES (CQMS) MEASURE TYPE: Process High Priority
Quality ID #65 (NQF 0069): Appropriate Treatment for Children with Upper Respiratory Infection (URI) National Quality Strategy Domain: Efficiency and Cost Reduction Meaningful Measure Area: Appropriate
More information2018 OPTIONS FOR INDIVIDUAL MEASURES: REGISTRY ONLY. MEASURE TYPE: Process
Quality ID #116 (NQF 0058): Avoidance of Antibiotic Treatment in Adults With Acute Bronchitis National Quality Strategy Domain: Efficiency and Cost Reduction 2018 OPTIONS FOR INDIVIDUAL MEASURES: REGISTRY
More informationAntimicrobial susceptibility
Antimicrobial susceptibility PATTERNS Microbiology Department Canterbury ealth Laboratories and Clinical Pharmacology Department Canterbury District ealth Board March 2011 Contents Preface... Page 1 ANTIMICROBIAL
More informationEuropean Committee on Antimicrobial Susceptibility Testing
European Committee on Antimicrobial Susceptibility Testing Routine and extended internal quality control as recommended by EUCAST Version 5.0, valid from 015-01-09 This document should be cited as "The
More informationnumber Done by Corrected by Doctor Dr Hamed Al-Zoubi
number 8 Done by Corrected by Doctor Dr Hamed Al-Zoubi 25 10/10/2017 Antibacterial therapy 2 د. حامد الزعبي Dr Hamed Al-Zoubi Antibacterial therapy Figure 2/ Antibiotics target Inhibition of microbial
More informationAntibiotic Usage Guidelines in Hospital
SUPPLEMENT TO JAPI december VOL. 58 51 Antibiotic Usage Guidelines in Hospital Camilla Rodrigues * Use of surveillance data information of Hospital antibiotic policy guidelines from Hinduja Hospital. The
More informationAppropriate Management of Common Pediatric Infections. Blaise L. Congeni M.D. Akron Children s Hospital Division of Pediatric Infectious Diseases
Appropriate Management of Common Pediatric Infections Blaise L. Congeni M.D. Akron Children s Hospital Division of Pediatric Infectious Diseases It s all about the microorganism The common pathogens Viruses
More informationRCH antibiotic susceptibility data
RCH antibiotic susceptibility data The following represent RCH antibiotic susceptibility data from 2008. This data is used to inform antibiotic guidelines used at RCH. The data includes all microbiological
More information2012 ANTIBIOGRAM. Central Zone Former DTHR Sites. Department of Pathology and Laboratory Medicine
2012 ANTIBIOGRAM Central Zone Former DTHR Sites Department of Pathology and Laboratory Medicine Medically Relevant Pathogens Based on Gram Morphology Gram-negative Bacilli Lactose Fermenters Non-lactose
More informationPIPERACILLIN- TAZOBACTAM INJECTION - SUPPLY PROBLEMS
PIPERACILLIN- TAZOBACTAM INJECTION - SUPPLY PROBLEMS The current supply of piperacillin- tazobactam should be reserved f Microbiology / Infectious Diseases approval and f neutropenic sepsis, severe sepsis
More informationAntibiotic Stewardship Program (ASP) CHRISTUS SETX
Antibiotic Stewardship Program (ASP) CHRISTUS SETX Program Goals I. Judicious use of antibiotics Decrease use of broad spectrum antibiotics and deescalate use based on clinical symptoms Therapeutic duplication:
More informationAntibiotics. Antimicrobial Drugs. Alexander Fleming 10/18/2017
Antibiotics Antimicrobial Drugs Chapter 20 BIO 220 Antibiotics are compounds produced by fungi or bacteria that inhibit or kill competing microbial species Antimicrobial drugs must display selective toxicity,
More informationMercy Medical Center Des Moines, Iowa Department of Pathology. Microbiology Department Antibiotic Susceptibility January December 2016
Mercy Medical Center Des Moines, Iowa Department of Pathology Microbiology Department Antibiotic Susceptibility January December 2016 These statistics are intended solely as a GUIDE to choosing appropriate
More informationIntrinsic, implied and default resistance
Appendix A Intrinsic, implied and default resistance Magiorakos et al. [1] and CLSI [2] are our primary sources of information on intrinsic resistance. Sanford et al. [3] and Gilbert et al. [4] have been
More informationChallenges Emerging resistance Fewer new drugs MRSA and other resistant pathogens are major problems
Micro 301 Antimicrobial Drugs 11/7/12 Significance of antimicrobial drugs Challenges Emerging resistance Fewer new drugs MRSA and other resistant pathogens are major problems Definitions Antibiotic Selective
More informationCopyright 2012 Diabetes In Control, Inc. For permission to reprint, please contact Heather Moran, Production Editor, at
Malignant Otitis Externa Inflammation and damage at the base of the skull due to an untreated outer ear P. aeruginosa most common organism Yellow-green drainage from the ear Odor Fever Deep inner ear pain
More informationEuropean Committee on Antimicrobial Susceptibility Testing
European Committee on Antimicrobial Susceptibility Testing Routine and extended internal quality control for MIC determination and disk diffusion as recommended by EUCAST Version 8.0, valid from 018-01-01
More informationAberdeen Hospital. Antibiotic Susceptibility Patterns For Commonly Isolated Organisms For 2015
Aberdeen Hospital Antibiotic Susceptibility Patterns For Commonly Isolated s For 2015 Services Laboratory Microbiology Department Aberdeen Hospital Nova Scotia Health Authority 835 East River Road New
More informationAntibiotics Affecting the Bacterial Cell Wall
chapter 44 UNIT 12 CHAPTER 44 MEDICATIONS FOR INFECTION Antibiotics Affecting the Bacterial Cell Wall Overview Antibiotics that affect the cell wall are bactericidal. This group of antibiotics includes
More informationConcise Antibiogram Toolkit Background
Background This toolkit is designed to guide nursing homes in creating their own antibiograms, an important tool for guiding empiric antimicrobial therapy. Information about antibiograms and instructions
More informationAntibiotic Updates: Part I
Antibiotic Updates: Part I Fredrick M. Abrahamian, DO, FACEP, FIDSA Health Sciences Clinical Professor of Emergency Medicine David Geffen School of Medicine at UCLA Los Angeles, California Financial Disclosures
More informationAMR Industry Alliance Antibiotic Discharge Targets
AMR Industry Alliance Antibiotic Discharge Targets List of Predicted No-Effect Concentrations (PNECs) The members of the AMR Industry Alliance have developed a unified approach to establishing discharge
More informationChapter 46. Learning Objectives (cont d)
Chapter 46 Antimicrobial Agents Learning Objectives Explain the major action and effects of drugs used to treat infectious diseases Identify criteria used to select an effective antimicrobial agent Identify
More informationCompliance of manufacturers of AST materials and devices with EUCAST guidelines
Compliance of manufacturers of AST materials and devices with EUCAST guidelines Data are based on questionnaires to manufacturers of materials and devices for antimicrobial susceptibility testing. The
More informationEinheit für pädiatrische Infektiologie Antibiotics - what, why, when and how?
Einheit für pädiatrische Infektiologie Antibiotics - what, why, when and how? Andrea Duppenthaler andrea.duppenthaler@insel.ch Limping patient local pain swelling tenderness warmth fever acute Osteomyelitis
More informationJanuary 2014 Vol. 34 No. 1
January 2014 Vol. 34 No. 1. and Minimal Inhibitory Concentration (MIC) Interpretive Standards for Testing Conditions Medium: diffusion: Mueller-Hinton agar (MHA) roth dilution: cation-adjusted Mueller-Hinton
More informationConsiderations in antimicrobial prescribing Perspective: drug resistance
Considerations in antimicrobial prescribing Perspective: drug resistance Hasan MM When one compares the challenges clinicians faced a decade ago in prescribing antimicrobial agents with those of today,
More informationBeta-lactams 1 รศ. พญ. มาล ยา มโนรถ ภาคว ชาเภส ชว ทยา. Beta-Lactam Antibiotics. 1. Penicillins 2. Cephalosporins 3. Monobactams 4.
Beta-lactams 1 รศ. พญ. มาล ยา มโนรถ ภาคว ชาเภส ชว ทยา จ ดประสงค การศ กษา เม อส นส ดการเร ยนการสอน และการศ กษาด วยตนเองเพ มเต ม น กศ กษาสามารถ 1. อธ บายกลไกการออกฤทธ และกลไกการด อยาของยากล ม penicillins
More informationAntimicrobial Susceptibility Testing: The Basics
Antimicrobial Susceptibility Testing: The Basics Susan E. Sharp, Ph.D., DABMM, FAAM Director, Airport Way Regional Laboratory Director, Regional Microbiology and Molecular Infectious Diseases Laboratories
More informationChildrens Hospital Antibiogram for 2012 (Based on data from 2011)
Childrens Hospital Antibiogram for 2012 (Based on data from 2011) Prepared by: Department of Clinical Microbiology, Health Sciences Centre For further information contact: Andrew Walkty, MD, FRCPC Medical
More informationQuality ID #66: Appropriate Testing for Children with Pharyngitis National Quality Strategy Domain: Efficiency and Cost Reduction
Quality ID #66: Appropriate Testing for Children with Pharyngitis National Quality Strategy Domain: Efficiency and Cost Reduction 2018 OPTIONS FOR INDIVIDUAL MEASURES: REGISTRY ONLY MEASURE TYPE: Process
More informationSelective toxicity. Antimicrobial Drugs. Alexander Fleming 10/17/2016
Selective toxicity Antimicrobial Drugs Chapter 20 BIO 220 Drugs must work inside the host and harm the infective pathogens, but not the host Antibiotics are compounds produced by fungi or bacteria that
More informationThe β- Lactam Antibiotics. Munir Gharaibeh MD, PhD, MHPE School of Medicine, The University of Jordan November 2018
The β- Lactam Antibiotics Munir Gharaibeh MD, PhD, MHPE School of Medicine, The University of Jordan November 2018 Penicillins. Cephalosporins. Carbapenems. Monobactams. The β- Lactam Antibiotics have
More information2017 Antibiogram. Central Zone. Alberta Health Services. including. Red Deer Regional Hospital. St. Mary s Hospital, Camrose
2017 Antibiogram Central Zone Alberta Health Services including Red Deer Regional Hospital St. Mary s Hospital, Camrose Introduction This antibiogram is a cumulative report of the antimicrobial susceptibility
More information3/23/2017. Kathryn G. Smith, PharmD PGY1 Pharmacy Resident Via Christi Hospitals Wichita, Inc. Kathryn G. Smith: Nothing to disclose
Kathryn G. Smith, PharmD PGY1 Pharmacy Resident Via Christi Hospitals Wichita, Inc Kathryn G. Smith: Nothing to disclose Describe the new updates and rationale for them Relay safety concerns with use of
More informationAnti-infection Agents
Supecef Pow. for Inj. 0.5g 1 Supecef Pow. for Inj. 1g 1 Cefuroxime Pow. for Inj. 750mg 1 Tatumcef Pow. for Inj 0.5g 2 Tatumcef Pow. for Inj 1g 2 Tatumcef Pow. For Inj. 2g 2 Cefazolin Injection 1g 3 Pisutam
More informationResponsible use of antibiotics
Responsible use of antibiotics Uga Dumpis MD, PhD Department of Infectious Diseases and Infection Control Pauls Stradiņs Clinical University Hospital Challenges in the hospitals Antibiotics are still effective
More informationCompliance of manufacturers of AST materials and devices with EUCAST guidelines
Compliance of manufacturers of AST materials and devices with EUCAST guidelines Data are based on questionnaires to manufacturers of materials and devices for antimicrobial susceptibility testing. The
More information- the details, where possible, of the antibiotic products these companies supply or have supplied.
Under the Freedom of Information Act 2000 please could you provide me with a list of all companies currently supplying antibiotics - or that have supplied antibiotics in the last three years - to Royal
More information2015 Antibiogram. Red Deer Regional Hospital. Central Zone. Alberta Health Services
2015 Antibiogram Red Deer Regional Hospital Central Zone Alberta Health Services Introduction. This antibiogram is a cumulative report of the antimicrobial susceptibility rates of common microbial pathogens
More informationBacterial Resistance of Respiratory Pathogens. John C. Rotschafer, Pharm.D. University of Minnesota
Bacterial Resistance of Respiratory Pathogens John C. Rotschafer, Pharm.D. University of Minnesota Antibiotic Misuse ~150 million courses of antibiotic prescribed by office based prescribers Estimated
More information2019 COLLECTION TYPE: MIPS CLINICAL QUALITY MEASURES (CQMS) MEASURE TYPE: Process High Priority
Quality ID #66: Appropriate Testing for Children with Pharyngitis National Quality Strategy Domain: Efficiency and Cost Reduction Meaningful Measure Area: Appropriate Use of Healthcare 2019 COLLECTION
More informationIntro Who should read this document 2 Key practice points 2 Background 2
Antibiotic Guidelines: Obstetric Anti-Infective Prescribing Guidelines Classification: Clinical Guideline Lead Author: Antibiotic Steering Committee Additional author(s): Kelly Alexander / Frances Garraghan
More informationIntravenous Antibiotic Therapy Information Leaflet
Scottish Adult Cystic Fibrosis Service Ninewells Hospital Dundee Intravenous Antibiotic Therapy Information Leaflet February 2008 Intravenous antibiotic therapy in cystic fibrosis Patients with cystic
More information