Ata Fen Inc. Ata Fen Vaccine Manufacturing Plant

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1 Ata Fen Inc. Ata Fen Inc. had been established as the sister company of Ege Vet Ltd., in Currently, Ata Fen Inc. is playing a leader role in many fields of veterinary medicine, prophylactic measures and proper breeding techniques. Ata Fen Inc. is located in Izmir/TURKEY and has six branch offices in Ankara, Istanbul, Bursa, Samsun, Hatay and Antalya. Every branch office has its own sales team and responsible area manager. There are total twenty five salesmen on the roads, responsible f covering certain parts of Turkey. Sales team is suppted by Sales Codinat, Sales and Planning Directs and Technical Consultants. All of these positions are taken by veterinarians. Ata Fen is the exclusive distribut of Wld Wide Sires in Turkey. Ata Fen is distributing frozen semen from high quality U.S. proven bulls all around Turkey. Marketing high quality, proven U.S. bovine semen has been a maj segment of Ata Fen's business. Ata Fen is in the position of being able to offer and provide the semen of various breeds of bulls at wide range of genetic specifications. Ata Fen is proud of its unique and efficient marketing netwk that covers all around Turkey. Ata Fen has played an imptant role by implementing prophylactic measures and proper breeding methods f livestock business. Veterinary pharmaceuticals, veterinary vaccines, feed additives, AI equipment and tools and various farm equipment are among its product range. Ata Fen Vaccine Manufacturing Plant As family members of Ata Fen Inc., we are proud of our veterinary vaccine manufacturing plant, which is in accdance with European Union Standards. This plant has been giving a great opptunity to our country and also to our neighb countries. Vaccine Manufacturing Plant of Ata Fen is located in Izmir/TURKEY. It is located in an area of 8500 square meters. The size of the closed facilities is total of 3330 square meter. In addition, a facility f testing animals is located in area of 400 square meters, as a separate unit. This facility has been designed f the manufacture of bacterial and viral veterinary vaccines. Right now, the bacterial vaccine unit has been completed. The unit is capable to produce all types of bacterial vaccines. The plant is fully equipped in accdance with the principles and rules of GMP and GLP. Ata Fen Inc. has launched the following vaccines in Turkish market; VBR Chauvoei, VBR K99+C, VBR Perfringens 3, VBR Polimix 5, VBR Colimix 7, Colimix 9, VBR Coli Sera+C, VBR Coli Sera, VBR Rev.1, VBR S19. No second hand equipment has been used in the facility. Water purifying system has a capacity of 300 liter per hour and is operated and controlled by computer system. It has a capacity of sting 3 tons of sterile and purified water. Clean room conditions, sterile air filtering, sterilization, and filling and packing systems have been designed and installed by following the international standards. Unit f testing animals is being designed by clean room principles and being operated in accdance with animal welfare rules. It is one of the few licensed units in our country.

2 Ege Vet Bull Stud The first private bull stud of Turkey has been established by Ege Vet in 1997 in Ulucak- Kemalpasa region of Izmir. It is fully equipped with high technology equipment f semen processing, freezing and sting. Five U.S. Holstein bulls of superi quality were impted in 1997 by plane from the U.S.A. Their names were Pert, Joey, Romania, Evan and Leighton. The sires of these five bulls were ranking as 2nd, 11th, 54th and 64th at the International Holstein Top 100 list. Ege Vet received the patent right and Certification of Turkish Standard Institute f its "Spermbank" trademark in A Simmental bull (Ratl) and a Brown Swiss bull (Trilot) were impted from Austria in These two bulls have been introduced to Turkish dairy and beef farmers as alternative breeds. Ege Vet has also perfmed the first frozen embryo transfer by using sexed male embryos in Turkey f achieving young bulls f its bull stud. In 1999, full blood, high quality Holstein young bulls were bn through frozen, male U.S. Holstein embryos. These four young Holstein bulls were named as Jed, Mascot, Etazon and Dr Carmichael. These bulls have been used successfully f semen production. Some Bulls from Our Bull Stud

3 What we market? What we do? Veterinary vaccines Dairy and beef farm consultation services Veterinary pharmaceuticals Artificial Insemination & Embryo Transfer Frozen bovine semen from WWS, USA Pet clinic Frozen bovine semen from Ege Vet Bull Stud Large animal practice Frozen buck semen Frozen bovine semen processing A.I. equipment and liquid nitrogen containers Vaccination programs Veterinary equipment and tools Bacterial vaccine production Feed additives Calf and lamb milk replacers

4 Licensed Veterinary Vaccines of ATA FEN INC. Name of the Vaccine Composition Indications (Diseases) Dose Amount Packing size VBR Chauvoei Clostridium chauvoeibacterin-toxoid Black Leg Disease 25 cattle dose 50 sheep-goat dose VBR K99+C Escherichia coli K99 and Clostridium perfringens Type C Bacterin-Toxoid Septicemia Toxemia 25 cattle dose 50 sheep-goat dose VBR Perfringens 3 Clostridium perfringens Type B, Clostridium perfringens Type C and Clostridium perfringens Type D Bacterin-Toxoid Over Eating Disease (Enterotoxemia Pulpy Kidney Disease) 25 cattle dose 50 sheep-goat dose VBR Polimix 5 VBR Colimix 7 Clostridium perfringens Type B, C, D; Clostridium novyi and Clostridium chauvoei Bacterin-Toxoid Clostridium perfringens Type B, C, D; Clostridium novyi, Clostridium septicum, Clostridium chauvoei and Escherichia coli Bacterin-Toxoid Over Eating Disease (Enterotoxemia Pulpy Kidney Disease) Necrotic Hepatitis (Black Disease) Black Leg Disease Haemrhagic Enteritis/Struck Lamb Dysentery Over Eating Disease (Enterotoxemia Pulpy Kidney Disease) Necrotic Hepatitis (Black Disease) Black Leg Disease Haemrhagic Enteritis/Struck Newbn Lamb Dysentery Malignant Edema, Bradzot Septicemia 25 cattle dose 50 sheep-goat dose 12,5 cattle dose 25 sheep-goat dose

5 Name of the Vaccine Composition Indications (Diseases) Dose Amount Packing size VBR Colimix 9 Clostridium perfringens Type B, C, D; Clostridium novyi Type A, Clostridium sdellii, Clostridium septicum, Clostridium chauvoei, Clostridium haemolyticum and Escherichia coli Bacterin-Toxoid Newbn Lamb Dysentery Haemrhagic Enteritis/Struck Over Eating Disease (Enterotoxemia Pulpy Kidney Disease) Necrotic Hepatitis (Black Disease) Malignant Edema, Bradzot Black Leg Disease (Bacillary ictero-haemoglobinuria=red Water Disease) Septicemia 12,5 cattle dose 25 sheep-goat dose VBR Coli Sera+C Antibody VBR Coli Sera Antibody VBR Rev.1 Conjunctival Escherichia coli O101:K-: K99 Clostridium perfringens Type C, Escherichia coli O101:K-: K99 Freeze-dried, live, attenuated Brucella melitensis Rev.1 Septicemia (caused by E. coli) Infections caused by Clostridium perfringens Type C Septicemia (caused by E. coli) Goat and sheep Brucellosis 1cattle dose, 2 sheep-goat dose 3 cattle dose, 6 sheep-goat dose 5 cattle dose, 10 sheep-goat dose 10 cattle dose, 20 sheepgoat dose 1cattle dose, 2 sheep-goat dose 3 cattle dose, 6 sheep-goat dose 5 cattle dose, 10 sheep-goat dose 10 cattle dose, 20 sheep-goat dose 25 doses 50 doses 75 doses 100 doses 200 doses 10 ml 30 ml 100 ml 10 ml 30 ml 100 ml 1 ml 2 ml 3 ml 4 ml 8 ml VBR S.19 Conjunctival Freeze-dried, live, attenuated Brucella abtus S.19 Bovine Brucellosis 20 doses, 40 doses, 60 doses, 80 doses, 100 doses, 1 ml 2 ml 3 ml 4 ml 5 ml Click f the presentation about Clostridial Vaccines & Antiserums F Veterinary Use of Ata Fen Inc.

6 Impted Veterinary Pharmaceuticals Alfamec 1 %:Ivermectin (Alfasan International B.V., Netherlands) Alfamine 10 %:Ketamin HCL (Alfasan International B.V., Netherlands) Amoxyphen 15 %: Amoxicillin trihydrate (Kela N.V., Belgium) Alfazyne 2 %:Xylazine HCL (Alfasan International B.V., Netherlands) Apoderm Spray: Chltetracycline HCL + CI Food Blue 5 (LabatiosOvejero S.A., Spain) Calfoset:Clacium Gluconate, Calcium Glycerophosphate, Magnesium Chlide (Krka, d.d., Slovenia) Co-Trimoxazole 24 %:Trimetophrim - Sulfametoxazole (Kela N.V., Belgium) Drymastiphen:Cloxacillin (Mastitis - Dry Cow Therapy) (Kela N.V., Belgium) Ege Vet D3: Vitamin D3 (Alfasan International B.V., Netherlands) Enjeflox 10 %:Enrofloxacin (KRKA, d.d., Slovenia) Injectade: Vitamin A, Vitamin D3, Vitamin E (Alfasan International B.V., Netherlands) Juraclox LC: Ampicillin Sodium, Cloxacillin Sodium (Jurox Pty. Limited, Australia) Juramate:Prostaglandine F2 alpha (Cloprostenol) (Jurox Pty. Limited, Australia) Lactomast: Neomycin + Procain Benzyl Penicilline (Kela N.V., Belgium) Linkospekto-Kombin 5/10:Lincomycin, Spectinomycin (Alfasan International B.V., Netherlands) Mames:Spyramicinadipate, Colistimethate sodium, Dexamethasone (LabatiosOvejero S.A., Spain) Metrisiklin: Chltetracycline HCL (Kela N.V., Belgium) Moxylan LA: Amoxicillin trihydrate (Jurox Pty. Limited, Australia) Mycogal 105: Spyramicinadipate (LabatiosOvejero S.A., Spain) Nitromectin:Nitroxynil, Ivermectin (LabatiosOvejero S.A., Spain) Paramectin:Abamectin (Jurox Pty. Limited, Australia) Pituisan:Oxytocine (Alfasan International B.V., Netherlands) Polyfil:Phosphylcholamine, Vitamin A, Vitamin E, Vitamin B12 (LabatiosOvejero S.A., Spain) Popantel:Praziquantel, Oxantelembonate, Pyrantelembonate (Jurox Pty. Limited, Australia) Prazivet:Praziquantel (Alfasan International B.V., Netherlands) Prolipen 20/20:Procain Benzyl Penicilline, Dihidrostreptomycinesulphate (Kela N.V., Belgium) Promectin PLUS: Praziquantel, abamectin (Jurox Pty. Limited, Australia) Rapidc:Dexamethazone Sodium Phosphate (Kela N.V., Belgium) Tetraoxyphen LA 20 %:Oxytetracycline (Kela N.V., Belgium) Verbenzole 2,5 %:Albendazole (Kela N.V., Belgium) Vitcomplex: Vitamin A, Vitamin D3, Vitamin B1, Vitamin B2, Vitamin B6, Nicotinamide, Vitamin B12, D- panthenol (Alfasan International B.V., Netherlands)

7 Impted Veterinary Vaccines Dog and Cat Biological Products Dog Vac R: Rabies Vaccine (Killed virus, LabatiosOvejero S.A., Spain) Large Animal Biological Products Bovi Sera: Antiserum (Arcanobacterium pyogenes- Escherichia coli- Mannheimiahaemolytica- Pasteurellamultocida- Salmonella typhimurium Antibody, Colado Serum Co., USA) Lepto 5: Leptospirosis Vaccine (Leptospiracanicola-grippotyphosa-hardjo-icterohaemrhagiae-pomonabacterin Colado Serum Co., USA) MannheimiaHaemolytica&PasteurellaMultocidaBacterin:MannheimiaHaemolytica - PasteurellaMultocidaBacterin (Colado Serum Co., USA) Mastivac: Combined Bacterin (Mastitis) (Streptococcus agalactiae- dysgalactiae - uberis -pyogenes- Escherichia coli Bov-10 - Bov-14 - Bov-15 - Suis-21 - J5, Staphylococcus aureus, Arcanobacterium pyogenes, LabatiosOvejero S.A., Spain) Mastivac TT: Combined Bacterin (Mastitis) (Streptococcus agalactiae -dysgalactiae - uberis- pyogenes, Staphylococcus aureus, Escherichia coli Bov 10, Arcanobacterium pyogenes LabatiosOvejero S.A., Spain) Vira Shield 6 + Somnus: Bovine Rhinotracheitis, Virus Diarrhea, Parainfluenza 3, Respiraty Synctial Virus Vaccine Killed Virus HaemophilusSomnusBacterin

8 Other Impted Products Feed Additives AmovitPolvo (LabatiosOvejero S.A., Spain) Amovit Liquid (LabatiosOvejero S.A., Spain) EDDI (EthylenediamineDihydroiodide, 4.6 % Organic Iodine Premix, SkyLabs Ltd, USA) Sky High Energy (SkyLabs Ltd, USA) Trimic (Techmix, USA) Tristart (Techmix, USA) Fresh Cow YMCP (Techmix, USA) Bovine Blulite Pellets (Techmix, USA) Enerboost (Vitalac, France) Glycolline Pellets (Vitalac, France) EDDI FEN (Ata Fen Inc., Turkey) EDDI REPRO (Ata Fen Inc., Turkey) Milk Replacers ElvClassico TU (Sofivo S.A.S., France) ElvEcomilk 100 TB TU (Sofivo S.A.S., France) Elv Perfecto TU (Sofivo S.A.S., France) Optiprim (Sofivo S.A.S., France) Benefit (Sofivo S.A.S., France) Artificial Insemination Equipment A.I. Sheath (50/Package, Minitube, Germany) Universal A.I. Sheath ( , Minitube, Germany) Semen Service Container (MVE, USA) Golden Phoenix Liquid Nitrogen Container (6 lt, China) Golden Phoenix Liquid Nitrogen Container (10 lt, China) Golden Phoenix Liquid Nitrogen Container (16 lt, China) Golden Phoenix Liquid Nitrogen Container (35 lt, China) Cryo Diffusion Liquid Nitrogen Container B 2003 (4.1 lt, France) Cryo Diffusion Liquid Nitrogen Container B 2009 (10.5 lt, France) Thawing Unit (Minitube, Germany) Water Thermometer