Table 2 Structures and properties of the study compounds with full citations < (ectoparasiticide)

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1 1 Table 2 tructures and properties of the study compounds with full citations Compound CA Molecular Log Kow pka Log Koc 1 oil DT50 1 tructure weight (l/kg) (days) Amoxicillin , H H 2 H H Diazinon < (ectoparasiticide) P Enrofloxacin , Florfenicol Cl H Cl H F H F

2 Compound CA Molecular Log Kow pka Log Koc 1 oil DT50 1 tructure weight (l/kg) (days) Levamisole (endoparasiticide) xytetracycline , 7.3, H H H H H H H H Phenylbutazone (antinflammatory) ulfadiazine H H 2 H 2

3 2 Compound CA Molecular Log Kow pka Log Koc 1 oil DT50 1 weight (l/kg) (days) Trimethoprim Tylosin tructure H H 2 H 2 H H H H

4 Boxall ABA, Fogg LA, Baird DJ, Telfer T, Lewis C, Gravell A, Boucard T Targeted Monitoring tudy for Veterinary Medicines. Environment Agency R&D Technical Report, Bristol, UK, Environment Agency 2 - angster J LGKW Databank: A Databank of Evaluated ctanol-water Partition Coefficients (Log P) on Microcomputer Diskette, Montreal, Canada, angster Research Laboratories 3 - U Pharmacopeia. 2003a. Amoxicillin and Clavulanate: Veterinary-ystemic. From: UP Veterinary Pharmaceutical Information Monographs, Rockville MD, UA, U Pharmacopeia, available [June 2005a] at RC PCKWI Version 1.6: Program for Windows 3.1, yracuse Y, UA, RC 5 - Hansch C, Leo A, Hoekman D Exploring QAR: Hydrophobic, Electronic and teric Constants (AC Professional Reference Book), Washington DC, UA, American Chemical ociety 6 - ougaku Pesticide Data Book, Tokyo, Japan, oft cience 7 - inclair CJ, Boxall ABA creening Level Exposure Assessment for Pesticide Metabolites, York, UK, Pesticide afety Directorate 8 - U Pharmacopeia. 2003b. Fluoroquinolones: Veterinary-ystemic. From: UP Veterinary Pharmaceutical Information Monographs, Rockville MD, UA, U Pharmacopeia, available [July 2005b] at Bayer (1996) Environmental Assessment for Enrofloxacin - BAYTRIL 3.23% Concentrate Antimicrobial olution (ADA EA), Rockville MD, UA, U Food and Drug Administration, Center for Veterinary Medicine, Available [July 2005] at;

5 chering Plough Animal Health Environmental Assessment for the Use of uflor Injectable olution in Cattle (ADA EA), Rockville MD, UA, U Food and Drug Administration, Center for Veterinary Medicine, Available [July 2005] at; U Pharmacopeia. 2003e. Tetracyclines: Veterinary-ystemic. From: UP Veterinary Pharmaceutical Information Monographs, Rockville MD, UA, U Pharmacopeia, available [July 2005e] at Blackwell PA, Boxall ABA, Kay P, oble H Evaluation of a lower tier exposure assessment model for veterinary medicines. J Agric Food Chem 53: U Pharmacopeia. 2003d. ulfonamides: Veterinary-ystemic. From: UP Veterinary Pharmaceutical Information Monographs, Rockville MD, UA, U Pharmacopeia, available [July 2005d] at U Pharmacopeia. 2003c. Macrolides: Veterinary-ystemic. From: UP Veterinary Pharmaceutical Information Monographs, Rockville MD, UA, U Pharmacopeia, available [July 2005c] at Carlson JC, Mabury A Degradation kinetics and mobility of chlortetracycline, tylosin and monensin agricultural soils. Abstracts Papers American Chemical ociety 228: 236

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