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SEQUENCES OF TEINS OF IMMUNOOGIC INTEEST Elvin Kabat, Tai Te Wu, Howard Bilofsky, Margaret eid-~liller, and Harold Perry ( 1983) Page; If 6; 20 Position -1 of 145'C (precursor heavy chains) should be

3 SEQUENCES OF TEINS OF IMMUNOOGIC INTEEST Elvin Kabat, Tai Te Wu, Howard Bilofsky, Margaret eid-~liller, and Harold Perry ( 1983) Page; If 6; 20 Position -1 of 145'C (precursor heavy chains) should be Phe 15; 31 Pau and Paul are the same protein 35 54; The antibody specificities for 10K44-71 and 10K light chains) should by anti-p-azobenzene arsenate (mouse kappa 65; 13 SPC178 and SPC176 (mouse lambda light chains) should be named as S and S176 65; 4 eferences for HOPC1, J698, H2061, S176, and H2020 (mouse lambda light 5 chains) should be Weigert, M, Cesari, IM, Yankovich, SJ & Cohn, M 6 (1970) Nature, 228, ; 7 eferences for W3159 and MOPC511 (mouse lambda light chains) should be 12 Cesari, IM & Weigert, M (1973) Proc Natl cad Sci US, 70, ; J558, XS104, and S178 (mouse lambda light chains) were sequenced completely, while HOPC1, J698, H2061, S176, H2020, W3159, and MOPC511 (mouse lambda light chains) were analyzed by amino acid sequence compositions 66; There is an additional reference to TEPC952 and M8-13 light chains) ie, Elliott, BW, Jr, Steiner, (1981) Fed Proc, 40, 1098 (mouse lambda & Eisen, HN 67; The statement in the notes of mouse lambda light chains, "The order of the genes has been determined as V1-J3-C3-J1-C1-V2-J2-C2-J4-C4," should be replaced by "There are two linkage groups: J3-C3-J1-C1 and J2-C2-J4-C4" 111; 23 Positions 13 and 14 of CM (human heavy chain subgroup III) should be Gln and ys respectively 168; 30 Position 171 of S43'C (light constant chain) should be sn 168; 35 Positions 142 and 143 of MOPC315 (light constant chain) should be Ser and Gly respectively, based on the translation from nucleotide sequences (Bothwell, M, Paskind; M, oth, M, Imanishi-Kari, T, ajewsky, K & Baltimore, D (1982) Nature, 298, ; Wu, GE, Govindi, N, Hozumi, N & Murialdo, H (1982) Nucl cids es, 10, ) 185; 52 Positions 258 and 263 of MOPC173 (heavy constant chain) have been revised by the authors to Pro and Val respectively 246; The position numbering for the codons of light chain variable region should read as 95, 95, 95B, 95C, 95D, 95E, 95F, 96, and 97 The human kappa J-segments (Hieter, P, Maizel, JV, Jr & eder, P (1982) J Biol Chem, 257, ) are as follows: *D In Yt 2( to, I N' :f: B< The by,u J2 E ll _,)5_ 96 TGG TC TTC PHE CTC TC IE 97 CG CT CT CT CC 98 TTC PHE TTT PHE TTC PHE TTC PHE TTC PHE 99 GGC GGC GGC GGC GGC 100 G CG CCT GG C 101 GGG GGG GGG GGG GGG 102 CC CC CC CC C 103 G YS G YS YS G YS CG 104 GTG CTG GTG GTG CTG 105 G GG GT GG GG 106 TC IE TC IE TC IE TC IE TT IE 107 YS YS YS YS YS 108 CGT CGT CGT CGT CGT Page 3

4 SEQUENCES OF J TEINS OF IMMUNOOGIC INTEEST Tabulation and nalysis of mino cid and Nucleic cid Sequences of Precursors, V-egions, C-egions, J-Chain,!32-Microglobulins, Major Histocompatibility ntigens, Thy-1, Complement, C-eactive Protein, Thymopoietin, Post-gamma Globulin, and a 2-Macroglobulin 1983 Elvin Kabat*, TaiTe Wu t, Howard Bilofsky t, Margaret eid-miller"t, and Harold Perry"t * Depts of Microbiology, Human Genetics and Development, and Neurology, Cancer Center/ Institute of Cancer esearch, College of Physicians and Surgeons, Columbia University, New York, NY and the National Institute of llergy and Infectious Diseases, Bethesda, MD t Depts of Biochemistry, Molecular Biology, and Cell Biology, and Engineering Sciences and pplied Mathematics, Northwestern University, Evanston, I and the Cancer Center, Northwestern University Medical School, Chicago, I Bolt Beranek and Newman Inc, Cambridge, M The collection and maintenance of this data base is sponsored through Contract N by the following components of the National Institutes of Health, Bethesda, MD 20205: Division of esearch esources National Cancer Institute National Institute of llergy and infectious Diseases National Institute of rthritis, Diabetes, Digestive and Kidney Diseases National Institute of General Medical Sciences US DEPTMENT OF HETH ND HUMN VICES Public Health Service National Institutes of Health (1983) Page 4

5 )\J Our listing,of se_quenc,es will be kept up to date Investigators are invited to send additional sequence data when accepted for publication Send two copies of the manuscript together with a letter of acceptance from a journal to: Dr E Kabat National lnstitutes of Health Building 4, oom ockville Pike Bethesda, Maryland If a computer tape is available, please send it to facilitate entering sequences -when published, three reprints should be provided If any published sequences have been overlooked or if any errors are found, please bring them to our attention Page 5

6 xxi TBlE OF CONTENTS PECUSO PECUSOS OF KPP IGHT CHINS 1 PECUSOS OF MBD IGHT CHINS 4 PECUSOS OF HEVY CHINS 6 PECUSO OF BET-2-MICOGOBUIN 10 PECUSOS OF MJO HISTOCOMPTIBIITY NTIGENS 12 VIBE EGION IGHT CHIN SEQUENCES HUMN KPP IGHT CHINS SUBGOUP I 14 HUMN KPP IGHT CHINS SUBGOUP II 20 HUMN KPP IGHT CHINS SUBGOUP Ill 23 HUMN KPP IGHT CHINS SUBGOUP IV 28 HUMN MBD IGHT CHINS SUBGOUP I 30 HUMN MBD IGHT CHINS SUBGOUP II 33 HUMN MBD IGHT CHINS SUBGOUP Ill 36 HUMN MBD IGHT CHINS SUBGOUP IV 39 HUMN MBD IGHT CHINS SUBGOUP V 41 HUMN MBD IGHT CHINS SUBGOUP VI 43 MOUSE KPP IGHT CHINS 45 MOUSE MBD IGHT CHINS 65 T KPP IGHT CHINS 68 BBIT KPP IGHT CHINS 70 BBIT MBD IGHT CHINS 82 GUINE PIG KPP IGHT CHINS 84 GUINE PIG MBD IGHT CHINS 86 DOG IGHT CHINS 88 PIG KPP IGHT CHINS 90 PIG MBD IGHT CHINS 92 HOSE KPP IGHT CHINS 94 CHICKEN MBD IGHT CHINS : 96 TUKEY MBD IGHT CHINS 98 SHK KPP IGHT CHINS 100 MISCENEOUS IGHT CHINS 102 VIBE EGIONS HEVY CHIN SEQUENCES HUMN HEVY CHINS SUBGOUP I 105 HUMN HEVY CHINS SUBGOUP II 109 HUMN HEVY CHINS SUBGOUP Ill 111 MOUSE HEVY CHINS SUBGOUP I 118 MOUSE HEVY CHINS SUBGOUP II 121 MOUSE HEVY CHINS SUBGOUP Ill 128 MOUSE HEVY CHINS SUBGOUP IV 138 MOUSE HEVY CHINS SUBGOUP V 140 T HEVY CHINS 144 BBIT HEVY CHINS 146 GUINE PIG HEVY CHINS 150 CT HEVY CHINS, 152 DOG HEVY CHINS 154 PIG HEVY CHINS 156 HOSE HEVY CHINS 158 CHICKEN HEVY CHINS 160 SHK HEVY CHINS 162 MISCENEOUS HEVY CHINS 164 CONSTNT EGION SEQUENCES IGHT CONSTNT CHINS 167 HEVY CONSTNT CHINS CH1 EGION 173 HEVY CONSTNT CHINS HINGE EGION 178 HEVY CONSTNT CHINS CH2 EGION 183 HEVY CONSTNT CHINS CH3 EGION 188 HEVY CONSTNT CHINS EXT ONG CH3 EGION 193 HEVY CONSTNT CHINS CH4 EGION 194 HEVY CONSTNT CHINS EXT ONG CH4 ND MEMBNE BOUND EGIONS 196 SEQUENCES OF ETED TEINS J CHIN 202 BET-2-MICOGOBUINS 204 MJO HISTOCOMPTIBIITY NTIGENS N EGION 206 MJO HISTOCOMPTIBIITY NTIGENS C1 EGION 208 MJO HISTOCOMPTIBIITY NTIGENS C2 EGION 210 MJO HISTOCOMPTIBIITY NTIGENS MEMBNE EGION 212 MJO HISTOCOMPTIBIITY NTIGENS CYTOPSMIC EGION 214 I EGION GENE DUCTS -CHIN 1 EGION 217 I EGION GENE DUCTS -CHIN 2 EGION 219 I EGION GENE DUCTS -CHIN MEMBNE BOUND EGION 221 I EGION GENE DUCTS B-CHIN B1 EGION 224 I EGION GENE DUCTS B-CHIN B2 EGION 226 I EGION GENE DUCTS 8-CHIN MEMBNE BOUND EGION 228 THY-1 NTIGENS 231 COMPEMENT COMPONENTS 233 MISCENEOUS ETED TEINS 238 CODONS OF NUCEIC CID SEQUENCES COD9NS OF PECUSO EGION IGHT CHIN 241 CODONS OF PECUSO EGION HEVY CHINS 243 CO DONS OF VIBE EGION IGHT CHINS 246 CODONS OF VIBE EGION HEVY CHINS 248 CODONS OF IGHT CONSTNT CHINS 251 CO DONS OF HEVY CONSTNT CHINS CH1 EGION 253 CODONS OF HEVY CONSTNT CHINS HINGE EGION 254 CODONS OF HEVY CONSTNT CHINS CH2 EGION 255 CODONS OF HEVY CONSTNT CHINS CH3 EGION 256 CODONS OF HEVY CONSTNT EXT ONG CH3 EGION 257 CODONS OF HEVY CONSTNT CHINS CH4 EGION 258 Page 6

7 xxii PEC (continued) CODONS OF HEVY CONSTNT EXT ONG CH4 ND MEMBNE BOUND EGIONS 259 CODONS OF MJO HISTOCOMPTIBIITY NTIGENS N EGION 261 CODONS OF MJO HISTOCOMPTIBIITY NTIGENS C1 EGION 262 CODONS OF MJO HISTOCOMPTIBIITY NTIGENS C2 EGION 263 CODONS OF MJO HISTOCOMPTIBIITY NTIGENS MEMBNE EGION 264 CODONS OF MJO HISTOCOMPTIBIITY NTIGENS CYTOPSMIC EGION 265 CODONS OF HUMN D SEGMENT 267 CODONS OF MOUSE D SEGMENT, 269 CO DONS OF MOUSE KPP J SEGMENT 272 CO DONS OF MOUSE MBD J SEGMENT 273 CODONS OF T KPP J SEGMENT 274 CODONS OF HUMN HEVY J SEGMENT 275 CODONS OF MOUSE HEVY J SEGMENT 276 PSEUDOGENES 277 SUMMY TBES MINO CID DISTIBUTION IN VIBE EGION IGHT CHINS 281 MINO CID DISTIBUTION IN VIBE EGION HEVY CHINS 283 CODON DISTIBUTION IN VIBE EGION IGHT CHINS 285 CODON DISTIBUTION IN VIBE EGION HEVY CHINS 288 VIBIITY POTS INDICES IGHT CHINS 292 HEVY CHINS 292 KPP IGHT CHINS 293 MBD IGHT CHINS 293 HUMN IGHT CHINS 294 HUMN HEVY CHINS 294 HUMN KPP IGHT CHINS 295 HUMN MBD IGHT CHINS 295 MOUSE KPP IGHT CHINS 296 BBIT KPP IGHT CHINS 296 HUMN KPP IGHT CHINS SUBGOUP I 297 HUMN HEVY CHINS SUBGOUP Ill 297 CYTOCHOMES C, 298 INDEX OF TEINS 299 INDEX OF NTIBODY SPECIFICITIES 318 Page 7

Supplemental Information. Discovery of Reactive Microbiota-Derived. Metabolites that Inhibit Host Proteases

Supplemental Information. Discovery of Reactive Microbiota-Derived. Metabolites that Inhibit Host Proteases Cell, Volume 168 Supplemental Information Discovery of Reactive Microbiota-Derived Metabolites that Inhibit Host Proteases Chun-Jun Guo, Fang-Yuan Chang, Thomas P. Wyche, Keriann M. Backus, Timothy M.