MIC Test Strip. for antimicrobial susceptibility testing
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1 for antimicrobial susceptibility testing Liofilchem Liofilchem Quantitative assay for determining the Minimum Inhibitory Concentration (M.I.C.) is a quantitative assay for determining the Minimum Inhibitory Concentration (M.I.C.) of antimicrobial agents against microorganisms and for detecting the resistance mechanisms. are porous strips with special features (International Patent) that are impregnated with a predefined concentration gradient of antibiotic, across 15 two-fold dilutions of a conventional M.I.C. method. On one side of the strip is indicated a M.I.C. scale in μg/ml and a code that identify the antimicrobial agent. For ESBL, MBL, GRD, AmpC and KPC detection, the double-sided gradient carries the appropriate diagnostic reagents. are available in a large variety of configurations. Each configuration is available in packages of 10, 30 and 100 tests. Mixed culture on Chromatic MH Meropenem Staphylococcus aureus ATCC Tigecycline M.I.C. = 0.19 method principle When the is applied onto an inoculated agar surface, the preformed exponential gradient of antimicrobial agent is immediately transferred to the agar matrix. After 18 hours incubation or longer, a symmetrical inhibition ellipse centered along the strip is formed. The MIC is read directly from the scale in terms of at the point where the edge of the inhibition ellipse intersects the strip. Other growth/inhibition patterns may also be seen for resistance detection methods. Staphylococcus aureus Vancomycin / Teicoplanin GRD+ BIBLIOGRAPHY Klebsiella pneumoniae Ertapenem / Ert. +Phenylboronic acid KPC + CLSI M100-S27, Performance Standards for Antimicrobial Susceptibility Testing. CLSI M7-A10, Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria that Grow Aerobically. CLSI M11-A8 Methods for Antimicrobial Susceptibility Testing of Anaerobic Bacteria. CLSI M11-S1 Performance Standards for Antimicrobial Susceptibility Testing of Anaerobic Bacteria. CLSI M27-A3. Reference Method for Broth Dilution Antifungal Susceptibility Testing of Yeasts; Approved Standard - Third Edition. CLSI M27-S4. Reference Method for Broth Dilution Antifungal Susceptibility Testing of Yeasts; Fourth Informational supplement. EUCAST. Breakpoint tables for interpretation of MICs and zone diameters Version 7.1, March 2017.
2 for ANTIMICROBIAL susceptibility testing AMIKACIN AK AMOXICILLIN AML AMOXICILLIN*-CLAVULANIC ACID (2/1) CLSI recommended AMOXICILLIN*-CLAVULANIC ACID (2 μg/ml) EUCAST recommended * AUG * AMC AMPICILLIN AMP AMPICILLIN*-SULBACTAM (2/1) CLSI recommended AMPICILLIN*-SULBACTAM (4 μg/ml) EUCAST recommended * AMS * SAM AZITHROMYCIN AZM AZTREONAM ATM AZTREONAM ATM BACITRACIN BA CEFACLOR CEC CEFAZOLIN KZ CEFEPIME FEP CEFIXIME CFM CEFOPERAZONE*-SULBACTAM (2/1) * CPS CEFOTAXIME CTX CEFOTAXIME CTX CEFOTETAN CTT CEFOXITIN FOX CEFPIROME CR CEFPODOXIME PX CEFTAROLINE CPT CEFTAROLINE CPT CEFTAZIDIME (FDA cleared) CAZ CEFTAZIDIME*-AVIBACTAM * CZA CEFTIBUTEN CTB CEFTIZOXIME CZX CEFTOBIPROLE BPR CEFTOLOZANE*-TAZOBACTAM (FDA cleared) * C/T
3 for ANTIMICROBIAL susceptibility testing CEFTRIAXONE CRO CEFTRIAXONE CRO CEFUROXIME CXM CEPHALOTHIN KF CHLORAMPHENICOL C CIPROFLOXACIN CIP CLARITHROMYCIN CLR CLINDAMYCIN (FDA cleared) CD CLOXACILLIN CX COLISTIN CS COLISTIN CS DALBAVANCIN (FDA cleared) DAL DAPTOMYCIN (Includes Ca 2+ ) DAP DELAFLOXACIN (FDA cleared) DLX DORIPENEM DOR DOXYCYCLINE DXT ENROFLOXACIN ENR ERTAPENEM ETP ERYTHROMYCIN (FDA cleared) E FLORFENICOL FFC FOSFOMYCIN (Includes Glucose-6-Phosphate) FOS FOSFOMYCIN (Includes Glucose-6-Phosphate) FOS FUSIDIC ACID FU GATIFLOXACIN GAT GEMIFLOXACIN GEM GENTAMICIN CN GENTAMICIN CN IMIPENEM IMI KANAMYCIN K LEVOFLOXACIN LEV
4 for ANTIMICROBIAL susceptibility testing LINEZOLID LNZ MARBOFLOXACIN MAR MECILLINAM MEC MEROPENEM (FDA cleared) MRP MEROPENEM MRP MEROPENEM*-VABORBACTAM (8 μg/ml) (FDA cleared) * M/V METRONIDAZOLE MTZ MOXIFLOXACIN MXF MUPIROCIN MUP MINOCYCLINE MN NALIDIXIC ACID NA NETILMICIN NET NORFLOXACIN NOR NITROFURANTOIN F OFLOXACIN OFX OXACILLIN OX PENICILLIN G P PENICILLIN G P PIPERACILLIN PIP PIPERACILLIN*-TAZOBACTAM (4 μg/ml) * TZP POLYMYXIN B PB QUINUPRISTIN-DALFOPRISTIN QDA RIFAMPICIN RD RIFAMPICIN RD SPECTINOMYCIN SPC SPIRAMYCIN SP STREPTOMYCIN S SULBACTAM SUL SULFAMETHOXAZOLE SMX TEDIZOLID (FDA cleared) TZD
5 for ANTIMICROBIAL susceptibility testing TEICOPLANIN TEC TELAVANCIN TLV TELAVANCIN (FDA cleared) TLV TEMOCILLIN TMO TETRACYCLINE TE TIAMULIN TIA TICARCILLIN*-CLAVULANIC ACID (2 μg/ml) * TTC TIGECYCLINE TGC TILMICOSIN TIL TOBRAMYCIN TOB TOBRAMYCIN TOB TRIMETHOPRIM TM TRIMETHOPRIM*-SULFAMETHOXAZOLE (1/19) * SXT VANCOMYCIN (FDA cleared) VA for ANTIFUNGAL susceptibility testing AMPHOTERICIN B AMB ANIDULAFUNGIN AND CASPOFUNGIN CAS FLUCONAZOLE FLU FLUCYTOSINE FC ISAVUCONAZOLE IVU ITRACONAZOLE ITC KETOCONAZOLE KE MICAFUNGIN MYC POSACONAZOLE POS VORICONAZOLE VO for KPC detection MEROPENEM / MEROPENEM + PHENYLBORONIC ACID / MRP/MBO ERTAPENEM / ERTAPENEM + PHENYLBORONIC ACID / ETP/EBO
6 ESBL for confirmation of Extended Spectrum Beta-Lactamase CEFEPIME/CEFEPIME+CLAVULANIC ACID (4 μg/ml) / CEFOTAXIME/CEFOTAXIME+CLAVULANIC ACID (4 μg/ml) / CEFTAZIDIME/CEFTAZIDIME+CLAVULANIC ACID (4 μg/ml) / FEP/FEL CTX/CTL CAZ/CAL MBL for detection of Metallo Beta-Lactamase IMIPENEM / IMIPENEM + EDTA / 1-64 IMIPENEM / IMIPENEM + EDTA / MEROPENEM / MEROPENEM + EDTA / IMI/IMD IMI/IMD MRP/MRD GRD for detection of Glycopeptide Resistance VANCOMYCIN / TEICOPLANIN / VA/TEC CTT/CXT ETP/ECX for AmpC detection CEFOTETAN / CEFOTETAN+CLOXACILLIN / ERTAPENEM / ERTAPENEM + CLOXACILLIN / for ANTIMYCOBACTERIAL susceptibility testing MTS Synergy Applicator Platform 1 unit MTS Synergy Delivery Tool 10 disposable applicators ETHAMBUTOL EB ETHIONAMIDE ET ISONIAZIDE IZ MTS Synergy Application System (International Patent) Accessories Rotating Plate Inoculator for confluent microbial growth on the petri dish DEN-1B McFarland densitometer with built-in adapter for 18 mm tubes A-16 Adapter for 16 mm tubes CKG18 calibration kit for DEN-1, for 18mm glass tubes CKG16 calibration kit for DEN-1, for 16mm glass tubes Storage Tube with Desiccant McFarland Standard Set McFarland 1 McFarland 2 McFarland tubes 5 tubes 1 tube 1 tube 1 tube
7 Ready to use culture media DESCRIPTION MUELLER HINTON AGAR II for antimicrobial susceptibility testing of non-fastidious organisms. MUELLER HINTON AGAR II + SHEEP BLOOD 5% for antimicrobial susceptibility testing of fastidious organisms. FORMAT 140 mm 140 mm MUELLER HINTON FASTIDIOUS AGAR (Horse blood 5% + 20 mg/l β-nad) EUCAST recommended: for antimicrobial susceptibility testing of Streptococcus spp., Haemophilus spp., 140 mm and some other fastidious organisms. MUELLER HINTON AGAR II + 2% NaCl for antimicrobial susceptibility testing of staphylococci with Oxacillin. CHROMATIC MH Chromogenic medium for the preliminary identification and susceptibility testing of bacteria directly 140 mm from clinical and environmental specimens. BRUCELLA BLOOD AGAR with HEMIN AND VITAMIN K1 for antimicrobial susceptibility testing of anaerobic bacteria. SCHADLER K AGAR (SHEEP BLOOD 5%) for antimicrobial susceptibility testing of anaerobic bacteria. HAEMOPHILUS TEST AGAR for Haemophilus spp. susceptibility testing. PACKAGING REF MIDDLEBROOK 7H11 AGAR for antimicrobial susceptibility testing of mycobacteria. R.P.M.I. AGAR (2% glucose + MOPS) for antifungal susceptibility testing mm E. coli ATCC SXT M.I.C. = S. pneumoniae ATCC S. aureus ATCC CRO FOX M.I.C. = M.I.C. = 1.5 S. pneumoniae ATCC E M.I.C. = C. krusei ATCC 6258 POS M.I.C. = S. aureus ATCC FU M.I.C. = 0.50 C. krusei VO M.I.C. = 0.25 P. aeruginosa ATCC TZP M.I.C. = 8 S. maltophilia ATCC IMI/IMD 4-256/1-64 E. coli DSM CTX/CTL / MBL+ ESBL+ E. coli CAZ/CAL / ESBL+ K. pneumoniae ATCC BAA-1144 CTT/CXT / AmpC+
8 Contact your local dealer or Liofilchem headquarter for availability. Argentina MedicaTec S.R.L. Tel Fax Denmark Biotech-IgG A/S Tel Fax Malaysia Premier Diagnostics Sdn Bhd Tel Fax Singapore Premier Diagnostics Pte Ltd Tel Fax Australia Integrated Sciences Pty Ltd Tel Fax Estonia Borsa Eesti OÜ Tel Fax borsa@borsa.ee Mexico Abalat, S.A. de C.V. Tel (01 55) Slovakia Bio G spol. s r.o. Tel Fax Austria IVD Uhl-Michelin e.u. Tel.:+43 (0) Fax: +43 (0) werner.uhl-michelin@ivd.at Finland Immuno Diagnostic Oy Tel Fax Netherlands EWC Diagnostics B.V. Tel +31 (0) carin.smale@ewcdiagnostics.com Slovenia Mediline d.o.o. Tel Fax Belarus Multi Lab Ltd. Tel.: Fax: multilab@multilab.by France i2a Tel Fax New Zealand Point View Laboratories Ltd Tel Fax info@pointviewlaboratories.com South Africa Davies Diagnostics (PTY Ltd) Tel Fax Belgium ELITech Group B.V. Tel +32 (0) Fax +32 (0) c.notte@elitechgroup.com Germany bestbion dx GmbH Tel Fax service@bestbion.com Norway Montebello Diagnostics AS Tel Fax Spain Werfen España, SAU Tel Fax Brazil Plast Labor Tel (21) (21) (21) (21) plabor@plastlabor.com.br Greece Varelas S.A. Tel Fax microbiology@varelas.gr Paraguay GT Scientific S.A. Tel Fax ventas@gtscientific.com.py Sweden Biotech-IgG AB Tel Fax ak@biotech-igg.com Bulgaria Elta 90M Tel Fax Hong Kong Bio-Gene Technology Ltd. Tel Fax info@bio-gene.com.hk Poland Argenta Spółka z ograniczoną odpowiedzialnością Sp.k. tel fax argenta@argenta.com.pl Switzerland Apteq AG Tel: Fax: Canada Alere Canada Tel (613) Fax (613) Hungary Frank Diagnosztika Kft. Tel , Fax Portugal Werfen Portugal, LDA Tel Fax product range only Thailand Envimed Co., Ltd. Tel Fax envimed@tru .co.th Chile Medica Tec de Chile S.A. Tel +56 (02) fax +56 (02) mrojas@medica-tec.cl Ireland Launch Diagnostics Ireland Tel Fax desruddy@launchdiagnostics.ie Russia Agros-International, Zao Tel +7 (812) Fax +7 (812) agros@agros-int.com Turkey Kemiteks Kimyevi Mad. Tic. Ltd. Sti. Tel Fax Colombia Annar Diagnóstica Tel Fax ventas@annardx.com Italy Liofilchem Tel Fax Saudi Arabia Gamsco Tel Fax drmalyousef@yahoo.com United Kingdom Launch Diagnostics Ltd Tel +44(0) Fax +44(0) enquiries@launchdiagnostics.com Czech Republic BioVendor Tel Fax Lithuania Biometrija tel fax Serbia Uni-Chem Tel Fax United States Liofilchem, Inc. Waltham, MA tel Liofilchem IVD In USA, available for products noted as "FDA Cleared" in the product list. Via Scozia zona ind.le, Roseto degli Abruzzi (Te) Italy Tel Fax liofilchem@liofilchem.net ref Rev.35 /
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