Animal and Grassland Research and Innovation Programme Products licensed for control of parasites in sheep in the Republic of Ireland

Transcription

1 Animal and Grassland Research and Innovation Programme Products licensed for control of parasites in in the Republic of Ireland (6) Turner Print Group.indd 1 24/01/ :00

2 Products licensed for control of parasites in in the Republic of Ireland Compiled by Dr Barbara Good Animal & Grassland Research and Innovation Centre, Teagasc, Mellows Campus, Athenry, Co. Galway, H65 R718 January 2018 The information in the tables was compiled from SPC data sheets on the Health Products Regulatory Authority ( ) and European Medicine Agency websites ( accessed on the 10/07/17 and to the best of the author s knowledge the information presented is correct at time of printing. The fact that a product is authorised and listed on the HPRA/EMA website does not necessarily mean that it is marketed in this country. As new information becomes available product details will be regularly updated. Always read the package leaflet and/or product label and follow recommendations prior to use (6) Turner Print Group.indd 2 24/01/ :00

3 Summary of ovine anthelmintics licensed for use in Republic of Ireland 1-BZ : Benzimidazoles (White Group) Albex 10 % oral Albex 2.5 % oral Bovex % Chanelle Animal Health Chanelle Animal Health Chanelle Pharmaceuticals Manufacturing Albendazole Albendazole Lungworm, Lungworm, Curazole 2.5 % W/V oral drench Univet Fenbendazole Curazole 5 % W/V oral drench Univet Fenbendazole Endospec 10% SC Endospec 2.5% SC Fenbenor 2.5 % w/v oral drench Fenzol 5 % oral worm drench for cattle and Keelogane SC 25 mg/ml oral Osmonds Flexiben 10 % SC oral Cross Vetpharm Group Cross Vetpharm Group Albendazole Albendazole Lungworm, Lungworm, Tapeworm, liver fluke (adult only) Pharvet (Ireland) Ltd Fenbendazole Norbrook Laboratories Cross Vetpharm Group Cross Vetpharm Group Fenbendazole Albendazole Albendazole Lungworm, Tapeworm, liver fluke (adult only) Lungworm, Oxfencare oral Ancare Ireland Panacur SC 2.5% W/V oral Parafend 2.265% oral Parafend 5% SC Parafend 9.06% oral Intervet Ireland Fenbendazole Norbrook Laboratories Norbrook Laboratories Norbrook Laboratories Tramazole 10 % oral drench Univet Albendazole Lungworm, Tramazole 2.5 % oral drench Univet Albendazole Lungworm, Valbazen 100 mg/ml total spectrum wormer Wormall 2.265% W/V Zerofen 2.5% oral Zoetis Ireland Albendazole Lungworm, Coyle Veterinary Products Ltd Chanelle Pharmaceuticals Manufacturing Fenbendazole Route of Trace elements 21 days Co, Se Co, Se 1 Co, Se Co, Se 1 Co, Se days (6) Turner Print Group.indd 3 24/01/ :00

4 2-LV: (Yellow Group) Chanaverm plus oral solution Duphalvasole 75 mg/ml Levacide 1.5 % W/V SC worm drench Levacide 75 mg/ml Levacide low volume worm drench 75mg/ml Trace elements Chanelle Pharmaceuticals Manufacturing Lungworm Co. 18 days Zoetis Ireland Lungworm 1 Norbrook Laboratories Norbrook Laboratories Norbrook Laboratories Lungworm 1 Lungworm 1 Lungworm 1 Levapharm 75 mg/ml Chem-Pharm Lungworm 1 Levicare Hi-mineral oral solution Vermisole 75 mg/ml solution for Vermisole worm drench for cattle and Ancare Ireland Lungworm Co, Se 21 days Bimeda Chemicals Lungworm 1 Bimeda Chemicals Lungworm 21 days Anthelmintic Groups Wormers for belong to one of 5 families or classes of drugs. Currently the orange and purple group are POM (prescription only medicines) in Ireland. Results from drench tests, as part of the STAP ( ) programme, revealed treatment failure in 49% of flocks. Results from Irish studies have reported worms resistant to white and yellow groups in over 88 % and 37 % respectively of Irish flocks examined. A recent study has confirmed multiple resistance to all 3 non-pom wormer groups in nematodes in a small (6) Turner Print Group.indd 4 24/01/ :00

5 3-ML: Macrocyclic Lactone (Clear Group) 4 Animec 0.8 mg/ml solution for Chanelle Pharmaceuticals Manufacturing Lungworm, Nasal Chanimec 0.8 mg/ml oral solution Chanelle Pharmaceuticals Lungworm, Nasal for Manufacturing Cydectin 0.1 % W/V oral solution Zoetis Ireland Moxidectin Lungworm 1 for Cydectin 1 % W/V injectable Zoetis Ireland Moxidectin Lungworm, Sheep 82 days solution for. Cydectin 20 mg/ml LA solution Zoetis Ireland Moxidectin Lungworm, Sheep 10 for for Dectomax 10 mg/ml solution for Zoetis Ireland Doramectin Lungworm, Sheep 70 days for cattle, and pigs Ecomectin 10 mg/ml solution for Eco Animal Health Lungworm, Sheep Enovex 1.0 % W/V solution for Norbrook Laboratories Lungworm, Sheep for cattle, and pigs Eprinex Multi 5mg/ml pour-on for Merial Animal Health Eprinomectin Lungworm Pour-on 2 days beef and dairy cattle, and Limited goats Genesis drench 0.8 mg / ml Ancare Ireland Abamectin Lungworm, Nasal 16 days abamectin oral solution Imec 10 mg / ml solution for Eco Animal Health Lungworm, Sheep Ivomec classic for cattle Merial Animal Health Lungworm, Sheep 22 days and 10 mg/ml Kilo-mec 1 % solution for C-Corp Lungworm, Sheep Macromectin 0.8 mg/ml oral Norbrook Laboratories Lungworm, Nasal solution for Mastermectin 10 mg/ml solution C-Corp Lungworm, Sheep for for cattle and pigs Mectaject 1 % W/V solution for Lungworm, Nasal Noromectin 1.0% W/v solution for Norbrook Laboratories Lungworm, Sheep for Noromectin drench 0.8 mg/ml Norbrook Laboratories Lungworm, Nasal oral solution for Noromectin multi Norbrook Laboratories Lungworm, Sheep Oramec drench for 0.8 Merial Animal Health Lungworm, Nasal 60 days mg/ml Ovimec 0.8 mg/ml oral solution Abamectin Lungworm, Nasal 16 days Ovimectin 10 mg/ml solution for Lungworm, grubs for and lice, Nasal Panomec 10 mg/ml solution for Merial Animal Health Lungworm, Sheep 22 days for cattle, and pigs Paramectin 0.08% W/V drench for Norbrook Laboratories Lungworm, Nasal Primectin 1 % W/V solution for Norbrook Laboratories Lungworm, Sheep Qualimec 10 mg/ml solution for Eco Animal Health Lungworm, Sheep Topimec 0.8 mg/ml oral solution for Turbomec for cattle and, 1 % W/V solution for Ultimectin 10 mg/ml solution for for cattle, and pigs Virbamec injectable solution for cattle, swine and 10 mg/ml Zearl 10 mg/ ml solution for for cattle and Chanelle Pharmaceuticals Manufacturing Lungworm, Nasal Lungworm, Sheep Norbrook Laboratories Lungworm, Sheep Virbac Lungworm, Sheep Elanco Animal Health Eli Doramectin Lungworm, Sheep Lilly and Company 3 70 days (6) Turner Print Group.indd 5 24/01/ :00

6 4-AD (Orange Group) available as POM Zolvix Novartis Elanco Monepantel Roundworms 7 days 5-SI (Purple Group) available as POM s Startect dual active oral solution Zoetis Ireland for l Also contains abamectin which belongs to the clear group. Derquantel abamectin Form Lungworm 1 Dual Active Wormers (products with more than one active against parasitic Roundworms) s Arrest Suspension Ancare Ireland Fenbendazole, 21 days Combizole Fenbendazole, 21 days Startect dual active oral solution for Zoetis Ireland Derquantel Abamectin Lungworm 1 Combinations (products with active s against parasitic roundworms and liver fluke i.e. wormers and flukicide combination) POM = Prescription Only Medicine See table on page (6) Turner Print Group.indd 6 24/01/ :00

7 Summary of flukicide activity Chemical actives available to treat for liver fluke in Liver fluke stage Early Immature Mature immature Triclabendazole Closantel + + Rafoxanide + + Nitroxynil + + Oxyclozanide + Albendazole + While no product has been authorised for the treatment of rumen fluke in ROI, there is evidence in the scientific literature that products containing oxyclozanide are effective in treating rumen fluke. Seek veterinary advice on treatment for rumen fluke. Summary of flukicides licensed for in Republic of Ireland Endofluke 100 mg/ml oral Triclabendazole Liver fluke 56 days Fasifree 10% W/V oral Triclabendazole Liver fluke 55 days Fasinex 5 % oral Novartis Animal Health UK Triclabendazole Liver fluke 55 days Tribex 5 % oral for Triclaben 5 % oral for Flukiver 5 % W/V oral Flukiver 50 mg/ml solution for Chanelle Animal Health Ltd Triclabendazole Liver fluke 56 days Chanelle Pharmaceuticals Manufacturing Eli Lilly and Company Elanco Animal Health Eli Lilly and Company Elanco Animal Health Triclabendazole Liver fluke 56 days Closantel Closantel Liver fluke,roundworms (only blood feeders), Nasal, Ticks (feeding at time of treatment) Liver fluke, Roundworms (only blood feeders), Nasal 77 days Solantel oral for Norbrook Closantel Liver fluke, barber s pole worm, 42 day Nasal Ranide 30 mg/ml oral Univet Rafoxanide Liver fluke, Nasal 60 days drench Ridafluke 30 mg/ml oral Chanelle Pharmaceuticals Rafoxanide Liver fluke 60 days Manufacturing Trodax 340 mg/ml solution Merial Animal Health Nitroxynil Liver fluke, Haemonchus contortus 60 days for Zanil fluke drench Intervet Ireland Oxyclozanide Liver fluke (adults only), Tapeworm segments. Albex 10% oral Chanelle Animal Health Ltd Albendazole Adult Liver fluke, Albex 2.5 % oral Chanelle Animal Health Ltd Albendazole Adult Liver fluke, Endospec 10% SC Cross VetPharm Group Albendazole Adult Liver fluke, Co, Se Endospec 2.5 % SC Cross VetPharm Group Albendazole Adult Liver fluke, Co, Se Keelogane SC 25mg/ml oral Cross VetPharm Group Albendazole Adult Liver fluke, Osmonds Flexiben 10% SC Cross VetPharm Group Albendazole Adult Liver fluke, oral Tramazole 10 % oral drench Univet Limited Albendazole Adult Liver fluke, Tramazole 2.5 % oral Univet Limited Albendazole Adult Liver fluke, drench Valbazan 100 mg/ml total Zoetis Ireland Limited Albendazole Adult Liver fluke, spectrum wormer 10days (6) Turner Print Group.indd 7 24/01/ :00

8 Combinations (Flukicide & Wormer) s (flukicide, wormer) Chan Broad Spec oral Chanelle Pharmaceuticals Manufacturing Rafoxanide, Nasal 60 days Closamectin 5 mg/ml mg/ml solution for for Closamectin solution for for cattle and Norbrook Laboratories Norbrook Laboratories Mange mites, Nasal Mange mites, Nasal Closiver 5 mg/ml mg/ml solution for for Norbrook Laboratories Mange mites, Nasal Combifluke for Norbrook Laboratories Tapeworm, Nasal 18 days Curafluke 5 % W/V oral drench Univet Rafoxanide, Fenbendazole Tapeworm 5 Cydectin Triclamox 1 mg/ml + 50 mg/ml oral solution for Duotech oral for Zoetis Ireland Norbrook Laboratories Triclabendazole, Moxidectin Liver fluke (all stages), Lungworm Tapeworm 31 days 18 days Endex 8.75% W/V oral for Novartis Animal Health UK Triclabendazole, Liver fluke, Lungworm 55 days Fasimec Duo 50 mg/ml + 1 mg/ml oral for Fenafluke 5 % w/v oral Novartis Animal Health UK Pharvet (Ireland) Triclabendazole, Rafoxanide, Fenbendazole Nasal Tapeworm 27 days 60 days Flukiver combi 50 mg/ml + 75 mg/ml oral Eli Lilly and Company Elanco Animal Health Mebendazole Tapeworm, Nasal 65 days Levafas C fluke and worm drench Norbrook Laboratories Oxyclozanide, Liver fluke (adult), Lungworm 6 days Levafas diamond fluke and worm drench Norbrook Laboratories Oxyclozanide, Liver fluke (adult), Lungworm Levafluke oral drench Biochem Ltd Rafoxanide, Liver fluke, Lungworm 60 days Orafluke 5 % W/V oral Interchem Ireland Ltd Rafoxanide, Fenbendazole Tapeworm 60 days Parafend plus oral Norbrook Laboratories Tapeworm, Nasal 18 days Pharmazan C oral for and cattle Chem-Pharm Oxyclozanide, Liver fluke (adult),, Lungworm 6 days Rafazole oral Chanelle Pharmaceuticals Manufacturing Rafoxanide, Liver fluke, Lungworm 60 days Supaverm Suspension Eli Lilly and Company Elanco Animal Health Mebendazole Tapeworm, Nasal, Ticks* 65 days Triazole fluke and worm drench Pharvet (Ireland) Rafoxanide, Liver fluke, Lungworm 60 days Univet multidose fluke and worm drench Univet Rafoxanide, Liver fluke, Lungworm 60 days (6) Turner Print Group.indd 8 24/01/ :00

9 Summary of ovine ectoparasticides licensed for use in Republic of Ireland 48 hours Butox 7.5 mg/ml pour-on Intervet Ireland Deltamethrin Lice, Blowfly strike, Pour-on Clik 5 % pour-on for Dicyclanil Blowfly strike Pour-on 40 days CLIK5 % pour-on for Elanco Europe Ltd Dicyclanil Blowfly strike Pour-on 40 days CLiK Extra 65mg/ml Pour-on Suspension for Sheep Clikzin 12.5 mg/ml pour-on for Elanco Europe Ltd Dicyclanil Blowfly strike Pour-on 40 days Novartis Animal Health UK Dicyclanil Blowfly strike Pour-on 7 days Cyperguard Concentrate for dip emulsion Cypermethrin Lice, Blowfly strike,, Sheep Scab Dip 1 Dectospot 10 mg/ml pour-on solution for cattle and Deltamethrin Lice, Blowfly strike,, Pour-on Deldadot 10mg/ml Pour-on Solution for Cattle and Sheep Deltamethrin Lice, Blowfly strike, Pour-on Deltanil 10mg/ml pour-on solution for cattle and Virbac France Deltamethrin Lice, Blowfly, Keds, Ticks Pour-on Ecofleece 10 % W/V dip concentrate Cypermethrin high Cis (80/20) Lice, Blowfly, Keds, Ticks Dip 1 Ectoflits summer and winter dip, 60% W/V concentrate Dimpylate (Diazinon) Blowfly strike Keds, Lice Scab Dip Ectofly 12.5 mg/ml pour-on solution for Cypermethrin high Cis (80/20) Headflies, Lice (biting), Blowfly strike, Ticks Pour-on 8 days Fly and lice spot on insecticide 1% w/v Zoetis Ireland Deltamethrin Lice, Blowfly strike, Spot-on Insecinor 10 mg/ml spot-on solution for cattle and Norbrook Laboratories Deltamethrin Lice, Blowfly strike, Spot-on Osmonds Goldfleece fly and winter dip 60% W/V concentrate for dip solution Dimpylate (Diazinon) Blowfly strike Keds, Lice, Sheep Scab Dip Ovisect 12.5 mg/ml pour-on solution for Osmond Ireland On-farm Business Cypermethrin high Cis (80/20) Headflies, Lice, Blowfly strike, Ticks Pour-on 8 days Spotinor 10 mg/ml spot-on solution for cattle and Norbrook Laboratories Deltamethrin Lice, Blowfly strike y, Spot-on Summer dip concentrate for dip emulsion Hygeia Chemicals Ltd Dimpylate Scab, Blowfly strike Dip Taktic 12.5% W/V concentrate for dip emulsion Intervet Ireland Amitraz Mange mites, Lice, Dip 2 Vetrazin 60 mg/ ml pour-on solution Elanco Europe, UK Cryomazine Blowfly strike Pour-on Winter dip concentrate for dip emulsion Hygeia Chemicals Ltd Diazinon Mange mites, Blowfly strike Dip (6) Turner Print Group.indd 9 24/01/ :00

10 Summary of ovine coccidiostats licensed for use in Republic of Ireland Baycox Multi 50mg/ml oral for Cattle, Pigs and Sheep Bayer Ltd Toltrazuril For the prevention of clinical signs of coccidiosis Baycox Sheep, 50mg/ml Bayer Toltrazuril For the prevention of clinical signs of coccidiosis Bovicox 50mg/ml oral for cattle and J & M Veterinary Sciences Toltrazuril For the prevention of clinical signs of coccidiosis Deccox 60.6 g/kg Premix for Medicated Feeding stuff Ridacox 50 mg/ml oral for cattle and Zoetis Ireland J & M Veterinary Sciences Decoquinate Toltrazuril For the treatment and prophylaxis of coccidiosis in lambs and calves during coccidial challenge by medication of the feed. As an aid in the control of coccidiosis in lambs, by medication of ewe feed. For the prevention of clinical signs of coccidiosis In feed : Zero days Tolracol 50 mg/ml oral for pigs, cattle and KRKA, dd., Novo mesto Toltrazuril For the prevention of clinical signs of coccidiosis Toltranil 50 mg/ml oral for pigs, cattle and KRKA, dd., Novo mesto Toltrazuril For the prevention of clinical signs of coccidiosis Tratol 50 mg/ml oral for pigs, cattle and KRKA, dd., Novo mesto Toltrazuril For the prevention of clinical signs of coccidiosis Vecoxan 2.5 mg/ml for lambs and calves Eli Liily & Company, Elanco Animal Health Diclazuril Prevention of coccidiosis caused by Eimeria crandallis and Eimeria If there is no recent and confirmed history of clinical coccidiosis, the precense of coccidian in the flock/herd should be confirmed by faecal sampling prior to treatment Zero days The information in the tables was compiled from SPC data sheets on the Health Products Regulatory Authority ( ) and European Medicine Agency websites ( accessed on the 10/07/17 and to the best of the author s knowledge the information presented is correct at time of printing. The fact that a product is authorised and listed on the HPRA/EMA website does not necessarily mean that it is marketed in this country. As new information becomes available, product details will be regularly updated. Always read the package leaflet and/or product label and follow recommendations prior to use (6) Turner Print Group.indd 10 24/01/ :00

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12 Contact details: Teagasc Head Office, Oak Park, Ireland. Tel: +353 (0) Fax: +353 (0) (6) Turner Print Group.indd 12 24/01/ :00