Prescribing medicines in pregnancy database

Transcription

1 Page 1 of 41 Prescribing medicines in pregnancy database 3 April 2012 This database is intended to provide information to health professionals planning the medical management of pregnant patients or patients intending to become pregnant. It is not presented as medical advice to health professionals or the public. The use of any medicine during pregnancy requires careful consideration of both risks and benefits by the treating health professional. Any decision about taking a medicine during pregnancy should: involve a health professional and the patient take into account: all available information on the medicine the specific circumstances This database must not be used as the sole basis of decision making in the use of medicines during pregnancy. The TGA does not provide advice on the use of medicines in pregnancy for specific cases. More information is available from obstetric drug information services in your State or Territory. The database does not include all therapeutic goods, because certain types of therapeutic good are usually exempt from pregnancy categorisation. Those that are included have been categorised using the Australian categorisation system for prescribing medicines in pregnancy. In addition to the category, the safety statement for each medicine or medicine class should be considered integral information about the medicine. In some cases there may be discrepancies between the published Product Information and the information in this database due to the process of ongoing revision. The pregnancy category and safety statement for some medicines that are no longer registered for use in Australia are presented in this database for information only. Likewise, the pregnancy category for medicines registered for use in men only is also presented for information purposes only. Database search By accessing the database, you acknowledge that you have read, understood and accept the introductory information Australian categorisation system for prescribing medicines in pregnancy and accept the basis on which this information is provided. Please note: you must have javascript enabled to use this search facility. Search by name Search by classification More information Search by name Type the generic name/active ingredient of the medicine (or part of the name). The medicine will appear, with its classification and Pregnancy Category. Click on the medicine to obtain the description of the category, and safety statements when applicable. For combination products, search the medicines individually. Search by active ingredient/generic name of a medicine Display All Reset Search Submit Search by classification level To select medicines by their pharmacological group or pharmacological action, select a classification level from the dropdown list. To view all medicines, click on Display All. Click on the medicine to obtain the description of the category, and safety statements when applicable. For combination products, search the medicines individually. Medicine Classification

2 Page 2 of 41 Level 1 Level 2 Level 3 All All All Search By Classification More information If you know the trade name of a medicine, then the name of the active ingredient can be found in the Australian Register of therapeutic Goods. More information on using medicines in pregnancy can be found in the Product Information or Consumer Medicine Information documents. For medicines approved after 2009, more information can be found in the Australian Public Assessment Report (AusPAR) for prescription medicines.

3 Page 3 of 41 Search results Drug Name Category Classification Level 1 Classification Level 2 Classification Level 3 abacavir B3 Antimicrobials Antiviral abatacept C Allergy and Immune abciximab C Cardiovascular Anticoagulants and thrombolytic abiraterone D Endocrine Antiandrogen acamprosate B2 Detoxifying Agents, Antidotes acarbose B3 Endocrine Hypoglycaemic acetazolamide B3 Cardiovascular Diuretics Carbonic anhydrase inhibitor acetazolamide (ophthalmic) B3 Ophthalmic Drugs acetylcholine B2 Ophthalmic Drugs acetylcysteine B2 Respiratory acetylcysteine (inhaled) B2 Respiratory Expectorants and mucolytics acetylcysteine (intravenous) B2 Detoxifying Agents, Antidotes aciclovir B3 Antimicrobials Antiviral aciclovir (topical) B3 Drugs used in acitretin X Drugs used in Topical antiviral ic actinomycin D (dactinomycin) D Antineoplastic Agents Antibiotic cytotoxic adalimumab C Allergy and Immune adapalene D Drugs used in Topical adefovir B3 Antimicrobials Antiviral adenosine B2 Cardiovascular Antiarrhythmics adrenaline A Cardiovascular Adrenergic stimulants aflibercept D Ophthalmic Drugs agalsidase alfa B2 Metabolism Agents used for the treatment of metabolic disorders agalsidase beta B2 Metabolism Agents used for the treatment of metabolic disorders agomelatine B1 Central Nervous alatrofloxacin B3 Antimicrobials Antibiotics Quinolones albendazole D Antimicrobials Anthelmintics alcuronium B2 Drugs Used in Neuromuscular blocking aldesleukin C Antineoplastic Agents alefacept C Allergy and Immune alemtuzumab B2 Antineoplastic Agents Monoclonal antibodies

4 Page 4 of 41 alendronate B3 Endocrine Agents affecting calcium and bone metabolism Bisphosphonates alfentanil C Central Nervous Analgesics and Antipyretics (see also non-steroidal anti-inflammatory ) Opioid analgesics alfuzosin B2 Genitourinary Prostate hyperplasia alginates/antacids A Alimentary Hyperacidity, reflux, ulcers alglucerase B3 Metabolism Agents used for the treatment of metabolic disorders alglucosidase alfa B1 Metabolism Agents used for the treatment of metabolic disorders aliskiren D Cardiovascular Antihypertensives Angiotensin II receptor antagonists and renin inhibitors allopurinol B2 Musculoskeletal alprazolam C Central Nervous Agents used in gout and hyperuricaemia Benzodiazepines alprenolol C Cardiovascular Beta-adrenergic blocking alteplase B1 Cardiovascular Fibrinolytic altretamine (hexamethylmelamine) D Antineoplastic Agents amantadine B3 Central Nervous Antiparkinson ambenonium chloride B2 Drugs Used in Myasthenia Gravis ambrisentan X Cardiovascular Endothelin receptor antagonist amethocaine B2 Ophthalmic Drugs amifostine B3 Antineoplastic Agents Non-cytotoxic supportive therapy amikacin D Antimicrobials Antibiotics Aminoglycosides amiloride C Cardiovascular Diuretics Potassium sparing diuretics aminocaproic acid B3 Cardiovascular Haemostatic aminoglutethimide D Antineoplastic Agents Hormonal antineoplastic aminoglutethimide D Endocrine Hormonal amiodarone C Cardiovascular Antiarrhythmics amisulpride C Central Nervous amitriptyline C Central Nervous Tricyclic antidepressants amlodipine C Cardiovascular Antihypertensives Calcium channel blockers ammonium chloride A Respiratory Expectorants and mucolytics amorolfine B3 Drugs used in Topical antifungals, antiseptics (see also antifungal ) amoxycillin A Antimicrobials Antibiotics Penicillins amphotericin B3 Antimicrobials Antifungal (see also topical antifungals) ampicillin A Antimicrobials Antibiotics Penicillins amprenavir B3 Antimicrobials Antiviral amsacrine D Antineoplastic Agents

5 Page 5 of 41 amylobarbitone C Central Nervous anagrelide B3 Antineoplastic Agents anakinra B1 Allergy and Immune Hypnotics and sedatives Barbiturates anastrozole C Antineoplastic Agents Hormonal antineoplastic ancestim B2 Blood and Haemopoietic Haemopoietic anecortave B1 Ophthalmic Drugs anidulafungin B3 Antimicrobials Antifungal (see also topical antifungals) anistreplase C Cardiovascular Fibrinolytic antithrombin III C Cardiovascular Haemostatic anti-thymocyte immunoglobulin C Allergy and Immune apixaban C Cardiovascular Anticoagulants and thrombolytic apomorphine B3 Central Nervous Antiparkinson apraclonidine B3 Ophthalmic Drugs aprepitant B1 Antineoplastic Agents Non-cytotoxic supportive therapy aprotinin B1 Cardiovascular Haemostatic argipressin B2 Endocrine Antidiuretics aripiprazole C Central Nervous arsenic trioxide X Antineoplastic Agents artemether with lumefantine D Antimicrobials Antimalarials articaine B3 Drugs Used in asenapine C Central Nervous aspirin C Central Nervous Local anaesthetics Analgesics and Antipyretics (see also non-steroidal anti-inflammatory ) atazanavir B2 Antimicrobials Antiviral atenolol C Cardiovascular Beta-adrenergic blocking atomoxetine B3 Central Nervous CNS stimulants atorvastatin D Cardiovascular Hypolipidaemic atovaquone B2 Antimicrobials Antibiotics atracurium C Drugs Used in Neuromuscular blocking atropine A Alimentary Antispasmodics atropine A Cholinergic and Anticholinergic Agents atropine methonitrate B2 Cholinergic and Anticholinergic Agents auranofin B3 Musculoskeletal Antirheumatoid

6 Page 6 of 41 aurothioglucose B2 Musculoskeletal Antirheumatoid azacitidine X Antineoplastic Agents Antimetabolites azatadine B2 Allergy and Immune azathioprine D Allergy and Immune azelaic acid B1 Drugs used in azelastine B3 Allergy and Immune Topical azithromycin B1 Antimicrobials Antibiotics Macrolide antibiotics azlocillin B3 Antimicrobials Antibiotics Penicillins aztreonam B1 Antimicrobials Antibiotics baclofen B3 Musculoskeletal Muscle relaxants balsalazide C Alimentary Antidiarrhoeals basiliximab D Allergy and Immune BCG B2 Vaccines Live attenuated virus vaccines becaplermin B2 Drugs used in Topical beclomethasone B3 Endocrine Corticosteroids Inhalation/intranasal beclomethasone B3 Respiratory Inhalational Preventative aerosols and inhalations belatacept C Allergy and Immune belladonna B2 Cholinergic and Anticholinergic Agents bendrofluazide C Cardiovascular Diuretics Thiazides, related diuretics and loop diuretics benserazide B3 Central Nervous Antiparkinson benzathine penicillin A Antimicrobials Antibiotics Penicillins benzhexol B1 Central Nervous benztropine B2 Central Nervous Antiparkinson Antiparkinson benzydamine (topical oropharyngeal) B2 Mouth Preparations benzyl benzoate B2 Drugs used in Topical antiparasitics benzylpenicillin A Antimicrobials Antibiotics Penicillins betahistine B2 Cardiovascular Vasodilators betamethasone (systemic) A Endocrine Corticosteroids ic betamethasone (topical) A Endocrine Corticosteroids Topical betaxolol C Cardiovascular Beta-adrenergic blocking betaxolol (ophthalmic) C Ophthalmic Drugs bethanechol B2 Cholinergic and Anticholinergic Agents

7 Page 7 of 41 bethanechol B2 Genitourinary Bladder function disorders bevacizumab D Antineoplastic Agents Monoclonal antibodies bevantolol C Cardiovascular Beta-adrenergic blocking bicalutamide D Antineoplastic Agents Hormonal antineoplastic bifonazole B3 Drugs used in Topical antifungals, antiseptics (see also antifungal ) bimatoprost B3 Ophthalmic Drugs bioallethrin B2 Drugs used in biperiden B2 Central Nervous Topical antiparasitics Antiparkinson bisacodyl A Alimentary Laxatives bismuth subcitrate B2 Alimentary Hyperacidity, reflux, ulcers bisoprolol C Cardiovascular Beta-adrenergic blocking bivalirudin C Cardiovascular Anticoagulants and thrombolytic bleomycin D Antineoplastic Agents Antibiotic cytotoxic boceprevir B2 Antimicrobials Antiviral bortezomib C Antineoplastic Agents bosentan X Cardiovascular Endothelin receptor antagonist botulinum type A B3 Musculoskeletal Muscle relaxants bretylium tosylate C Cardiovascular Antiarrhythmics brimonidine tartrate B1 Ophthalmic Drugs brinzolamide B3 Ophthalmic Drugs bromazepam C Central Nervous Benzodiazepines bromhexine A Respiratory Expectorants and mucolytics bromocriptine (injection) B2 Endocrine Pituitary inhibitors bromocriptine (oral) A Endocrine Pituitary inhibitors brompheniramine A Allergy and Immune budesonide A Endocrine Corticosteroids Inhalation/intranasal budesonide A Respiratory Inhalational Preventative aerosols and inhalations budesonide (systemic) B3 Alimentary Antidiarrhoeals bumetanide C Cardiovascular Diuretics Thiazides, related diuretics and loop diuretics bupivacaine A Drugs Used in buprenorphine C Central Nervous bupropion B2 Agents used in dependency states buspirone B1 Central Nervous Local anaesthetics Analgesics and Antipyretics (see also non-steroidal anti-inflammatory ) Antianxiety Opioid analgesics busulfan D Antineoplastic Agents Alkylating

8 Page 8 of 41 butoconazole B3 Antimicrobials Antifungal (see also topical antifungals) cabazitaxel D Antineoplastic Agents Antimetabolites cabergoline B1 Endocrine Pituitary inhibitors caffeine A Central Nervous calcipotriol B1 Drugs used in CNS stimulants Topical calcitonin B2 Endocrine Agents affecting calcium and bone metabolism calcitriol B3 Endocrine Agents affecting calcium and bone metabolism calcium carbimide A Agents used in dependency states camustine D Antineoplastic Agents Alkylating canakinumab B3 Allergy and Immune candesartan cilexetil D Cardiovascular Antihypertensives Angiotensin II receptor antagonists and renin inhibitors capecitabine D Antineoplastic Agents Antimetabolites captopril D Cardiovascular Antihypertensives Angiotensin converting enzyme (ACE) inhibitors carbachol B2 Ophthalmic Drugs carbamazepine D Central Nervous carbetocin C Genitourinary Agents acting on the uterus carbidopa B3 Central Nervous Antiparkinson carbimazole C Endocrine Antithyroid carboplatin D Antineoplastic Agents carboprost D Genitourinary Agents acting on the uterus carvedilol C Cardiovascular Beta-adrenergic blocking cascara A Alimentary Laxatives caspofungin B3 Antimicrobials Antifungal (see also topical antifungals) cefaclor B1 Antimicrobials Antibiotics Cephalosporins cefepime B1 Antimicrobials Antibiotics Cephalosporins cefodizime B2 Antimicrobials Antibiotics Cephalosporins cefotaxime B1 Antimicrobials Antibiotics Cephalosporins cefotetan B1 Antimicrobials Antibiotics Cephalosporins cefoxitin B1 Antimicrobials Antibiotics Cephalosporins cefpirome B2 Antimicrobials Antibiotics Cephalosporins cefpodoxime B1 Antimicrobials Antibiotics Cephalosporins ceftazidime B1 Antimicrobials Antibiotics Cephalosporins ceftriaxone B1 Antimicrobials Antibiotics Cephalosporins cefuroxime B1 Antimicrobials Antibiotics Cephalosporins

9 Page 9 of 41 celecoxib B3 Musculoskeletal cephalexin A Antimicrobials Antibiotics Cephalosporins cephalothin A Antimicrobials Antibiotics Cephalosporins cephamandole B1 Antimicrobials Antibiotics Cephalosporins cephazolin B1 Antimicrobials Antibiotics Cephalosporins cerivastatin D Cardiovascular Hypolipidaemic certolizumab C Allergy and immune system cetirizine B2 Allergy and Immune cetrorelix D Endocrine Pituitary inhibitors cetuximab D Antineoplastic Agents Monoclonal antibodies cetylpyridinium A Drugs used in Topical antifungals, antiseptics (see also antifungal ) chenodeoxycholic acid B3 Alimentary Cholelitholytics chloral hydrate A Central Nervous Hypnotics and sedatives chlorambucil D Antineoplastic Agents Alkylating chloramphenicol A Antimicrobials Antibiotics chloramphenicol (ophthalmic) A Ophthalmic Drugs chlorcyclizine B3 Allergy and Immune chlordiazepoxide C Central Nervous chlorhexidine A Drugs used in chlormethiazole A Central Nervous Benzodiazepines Topical antifungals, antiseptics (see also antifungal ) Hypnotics and sedatives chloroquine (prophylaxis) A Antimicrobials Antimalarials chloroquine (treatment) D Antimicrobials Antimalarials chlorothiazide C Cardiovascular Diuretics Thiazides, related diuretics and loop diuretics chlorpheniramine A Allergy and Immune chlorpromazine C Central Nervous Phenothiazines chlorpropamide C Endocrine Hypoglycaemic chlorquinaldol A Drugs used in Topical antifungals, antiseptics (see also antifungal ) chlorthalidone C Cardiovascular Diuretics Thiazides, related diuretics and loop diuretics cholera vaccine (killed) B2 Vaccines Killed vaccines cholera vaccine (live) B2 Vaccines Live attenuated virus vaccines cholestyramine B2 Cardiovascular Hypolipidaemic choriogonadotropin alfa (rch) B3 Endocrine Ovulation inducers Gonadotrophins ciclesonide B3 Endocrine Corticosteroids Inhalation/intranasal

10 Page 10 of 41 ciclesonide B3 Respiratory Inhalational Preventative aerosols and inhalations ciclopirox B3 Antimicrobials Antifungal (see also topical antifungals) cidofovir D Antimicrobials Antiviral cilazapril D Cardiovascular Antihypertensives Angiotensin converting enzyme (ACE) inhibitors cilostazol B3 Cardiovascular Vasodilators cimetidine B1 Alimentary Hyperacidity, reflux, ulcers cinacalcet B3 Endocrine Agents affecting calcium and bone metabolism cinchocaine A Drugs Used in Local anaesthetics ciprofloxacin B3 Antimicrobials Antibiotics Quinolones cisapride B1 Alimentary Hyperacidity, reflux, ulcers cisatracurium besylate C Drugs Used in Neuromuscular blocking cisplatin D Antineoplastic Agents citalopram C Central Nervous Selective serotonin reuptake inhibitors (SSRIs) cladribine D Antineoplastic Agents Antimetabolites clarithromycin B3 Antimicrobials Antibiotics Macrolide antibiotics clavulanic acid B1 Antimicrobials Antibiotics clemastine A Allergy and Immune clevidipine C Cardiovascular Antihypertensives Calcium channel blockers clindamycin A Antimicrobials Antibiotics clindamycin A Genitourinary Topical vaginal medication clioquinol A Antimicrobials clobazam C Central Nervous Benzodiazepines clodronate B3 Endocrine Agents affecting calcium and bone metabolism Bisphosphonates clofarabine D Antineoplastic Agents Antimetabolites clofazimine C Antimicrobials Antituberculotics and antileprotics clofibrate B1 Cardiovascular Hypolipidaemic clomiphene B3 Endocrine Ovulation inducers Gonadotrophins clomipramine C Central Nervous clonazepam C Central Nervous clonazepam C Central Nervous Benzodiazepines Tricyclic antidepressants clonidine B3 Cardiovascular Antihypertensives clopamide C Cardiovascular Diuretics Thiazides, related diuretics and loop diuretics clopidogrel B1 Cardiovascular Anticoagulants and thrombolytic

11 Page 11 of 41 clorazepate C Central Nervous clotrimazole A Drugs used in Benzodiazepines Topical antifungals, antiseptics (see also antifungal ) clotrimazole A Genitourinary Topical vaginal medication cloxacillin A Antimicrobials Antibiotics Penicillins clozapine C Central Nervous codeine A Central Nervous Analgesics and Antipyretics (see also non-steroidal anti-inflammatory ) Opioid analgesics codeine A Respiratory Antitussives colaspase D Antineoplastic Agents Antimetabolites colchicine D Musculoskeletal Agents used in gout and hyperuricaemia colestipol B2 Cardiovascular Hypolipidaemic colistimethate B2 Antimicrobials Antibiotics colistin IV with colistimethate B2 Antimicrobials Antibiotics corifollitropin alfa B3 Endocrine Ovulation inducers Gonadotrophins corticotrophin A Endocrine Pituitary hormones cortisone A Endocrine Corticosteroids ic crotamiton B2 Drugs used in cyclizine B3 Allergy and Immune Topical antiparasitics cyclopenthiazide C Cardiovascular Diuretics Thiazides, related diuretics and loop diuretics cyclopentolate B2 Ophthalmic Drugs cyclophosphamide D Antineoplastic Agents Alkylating cyclosporin C Allergy and Immune cyproheptadine A Allergy and Immune cyproterone acetate (10 mg daily or higher PO) cyproterone acetate (2 mg daily PO) D Endocrine Antiandrogens B3 Endocrine Antiandrogens cysteamine bitartate B3 Metabolism Agents used for the treatment of metabolic disorders cytarabine D Antineoplastic Agents Antimetabolites dabigatran etexilate C Cardiovascular Anticoagulants and thrombolytic dacarbazine D Antineoplastic Agents Alkylating daclizumab C Allergy and Immune dactinomycin D Antineoplastic Agents Antibiotic cytotoxic dalfopristin with quinupristin B3 Antimicrobials Antibiotics dalteparin C Cardiovascular Anticoagulants and thrombolytic

12 Page 12 of 41 danaparoid C Cardiovascular Anticoagulants and thrombolytic danazol D Endocrine Pituitary inhibitors dantrolene B2 Musculoskeletal dapoxetine C Central Nervous Muscle relaxants Selective serotonin reuptake inhibitors (SSRIs) dapsone B2 Antimicrobials Antituberculotics and antileprotics daptomycin B1 Antimicrobials Antibiotics darbepoetin alfa B3 Blood and Haemopoietic Haemopoietic darifenacin B3 Genitourinary Prostate hyperplasia darunavir B2 Antimicrobials Antiviral dasatinib D Antineoplastic Agents Tyrosine kinase inhibitors daunorubicin D Antineoplastic Agents Antibiotic cytotoxic deferasirox C Detoxifying Agents, Antidotes deferiprone D Detoxifying Agents, Antidotes degarelix D Antineoplastic Agents Hormonal antineoplastic delavirdine B3 Antimicrobials Antiviral demeclocycline D Antimicrobials Antibiotics Tetracyclines denosumab D Endocrine Agents affecting calcium and bone metabolism desferrioxamine B3 Detoxifying Agents, Antidotes desflurane B3 Drugs Used in desipramine C Central Nervous General anaesthetics Tricyclic antidepressants desirudin B3 Cardiovascular Anticoagulants and thrombolytic desloratadine B1 Allergy and Immune desmopressin B2 Endocrine Antidiuretics desogestrel with ethinyloestradiol B3 Contraceptive Agents Oral contraceptives desonide B3 Drugs used in desvenlafaxine B2 Central Nervous Topical dexamethasone A Endocrine Corticosteroids ic dexamphetamine B3 Central Nervous dexchlorpheniramine A Allergy and Immune CNS stimulants dexfenfluramine B3 Metabolism Anorectic and weight reducing dexmedetomidine B1 Central Nervous Hypnotics and sedatives dextromethorphan A Respiratory Antitussives

13 Page 13 of 41 dextromoramide C Central Nervous dextropropoxyphene C Central Nervous diazepam C Central Nervous Analgesics and Antipyretics (see also non-steroidal anti-inflammatory ) Analgesics and Antipyretics (see also non-steroidal anti-inflammatory ) Benzodiazepines Opioid analgesics Opioid analgesics diazoxide C Cardiovascular Antihypertensives diclofenac C Musculoskeletal dicloxacillin B2 Antimicrobials Antibiotics Penicillins dicyclomine hydrochloride B1 Alimentary Laxatives didanosine B2 Antimicrobials Antiviral dienoestrol X Endocrine Oestrogens (see also oral contraceptives) dienogest with ethinyloestradiol B3 Contraceptive Agents Oral contraceptives dienosliterol B1 Genitourinary Topical vaginal medication diethylcarbamazine B2 Antimicrobials Anthelmintics diethylpropion B2 Metabolism Anorectic and weight reducing diflunisal C Musculoskeletal digoxin and other cardiac glycosides A Cardiovascular Cardiac inotropic digoxin immune fab B2 Detoxifying Agents, Antidotes dihydrocodeine A Central Nervous Analgesics and Antipyretics (see also non-steroidal anti-inflammatory ) Opioid analgesics dihydrocodeine A Respiratory Antitussives dihydroergotamine C Cardiovascular Antimigraine preparations dihydrotachysterol B3 Endocrine Agents affecting calcium and bone metabolism diltiazem C Cardiovascular Antihypertensives Calcium channel blockers dimenhydrinate A Central Nervous Antiemetics, antinauseants dinoprost C Genitourinary Agents acting on the uterus dinoprostone (prostaglandin E2) C Genitourinary Agents acting on the uterus diphenhydramine A Allergy and Immune diphenhydramine A Central Nervous Antiemetics, antinauseants diphenoxylate C Alimentary Antidiarrhoeals diphenylamine A Allergy and Immune diphenylpyraline B2 Allergy and Immune diphtheria vaccine A Vaccines Killed vaccines diphtheria-tetanus vaccine A Vaccines Killed vaccines

14 Page 14 of 41 dipivefrine B2 Ophthalmic Drugs dipyridamole B1 Cardiovascular Vasodilators disodium etidronate B3 Endocrine Agents affecting calcium and bone metabolism disopyramide B2 Cardiovascular Antiarrhythmics disulfiram B2 Agents used in dependency states dithranol B2 Drugs used in Topical dobutamine B2 Cardiovascular Adrenergic stimulants docetaxel D Antineoplastic Agents Antimetabolites docusate sodium A Alimentary Laxatives dofetilide D Cardiovascular Antiarrhythmics dolasetron B1 Central Nervous domperidone B2 Central Nervous Antiemetics, antinauseants Antiemetics, antinauseants donepezil B3 Cholinergic and Anticholinergic Agents dopamine B3 Cardiovascular Adrenergic stimulants doripenem B2 Antimicrobials Antibiotics dornase alfa B1 Respiratory dorzolamide B3 Ophthalmic Drugs dothiepin C Central Nervous Tricyclic antidepressants doxazosin B3 Cardiovascular Antihypertensives doxepin C Central Nervous Tricyclic antidepressants doxorubicin D Antineoplastic Agents Antibiotic cytotoxic doxycycline D Antimicrobials Antibiotics Tetracyclines doxycycline (antimalarial) D Antimicrobials Antimalarials doxylamine A Allergy and Immune dronedarone D Cardiovascular Antiarrhythmics droperidol C Central Nervous Butyrophenones drospirenone and ethinyloestradiol B3 Contraceptive Agents Oral contraceptives drotrecogin alfa C Cardiovascular Haemostatic duloxetine B3 Central Nervous Selective serotonin reuptake inhibitors (SSRIs) dutasteride X Genitourinary Prostate hyperplasia dydrogesterone D Endocrine Progestogens (see also oral contraceptives) econazole A Drugs used in Topical antifungals, antiseptics (see also antifungal ) econazole A Genitourinary Topical vaginal medication ecothiopate B2 Ophthalmic Drugs

15 Page 15 of 41 eculizumab B2 Allergy and Immune efalizumab C Allergy and Immune efavirenz D Antimicrobials Antiviral eflornithine B3 Drugs used in Topical eformoterol B3 Respiratory Inhalational Bronchospasm relaxants eletriptan B1 Cardiovascular Antimigraine preparations eltrombopag B3 Blood and Haemopoietic Haemopoietic emetine A Respiratory Expectorants and mucolytics emtricitabine B1 Antimicrobials Antiviral enalapril D Cardiovascular Antihypertensives Angiotensin converting enzyme (ACE) inhibitors enflurane A Drugs Used in General anaesthetics enfuvirtide B2 Antimicrobials Antiviral enoxacin B3 Antimicrobials Antibiotics Quinolones enoxaparin C Cardiovascular Anticoagulants and thrombolytic entacapone B3 Central Nervous Antiparkinson entecavir B3 Antimicrobials Antiviral ephedrine A Cardiovascular Adrenergic stimulants ephedrine A Respiratory Inhalational Bronchospasm relaxants epirubicin D Antineoplastic Agents Antibiotic cytotoxic eplerenone B3 Cardiovascular Diuretics epoetin alfa B3 Blood and Haemopoietic epoetin beta (rch) B3 Blood and Haemopoietic epoetin lambda (rch) B3 Blood and Haemopoietic Haemopoietic Haemopoietic Haemopoietic epoprostenol B1 Cardiovascular Vasodilators eprosartan D Cardiovascular Antihypertensives Angiotensin II receptor antagonists and renin inhibitors eptacog alfa (activated Factor VII - rch) B1 Cardiovascular Haemostatic eptifibatide C Cardiovascular Anticoagulants and thrombolytic eptotermin alfa D Musculoskeletal Osteogenic ergometrine C Genitourinary Agents acting on the uterus ergotamine C Cardiovascular Antimigraine preparations erlotinib C Antineoplastic Agents Tyrosine kinase inhibitors ertapenem B3 Antimicrobials Antibiotics erythromycin A Antimicrobials Antibiotics Macrolide antibiotics

16 Page 16 of 41 erythropoietin B3 Blood and Haemopoietic escitalopram C Central Nervous Haemopoietic Selective serotonin reuptake inhibitors (SSRIs) esmolol C Cardiovascular Beta-adrenergic blocking esomeprazole B3 Alimentary Hyperacidity, reflux, ulcers estramustine D Antineoplastic Agents Alkylating etanercept B2 Allergy and Immune ethacrynic acid C Cardiovascular Diuretics Thiazides, related diuretics and loop diuretics ethambutol A Antimicrobials Antituberculotics and antileprotics ethinyloestradiol B3 Endocrine Oestrogens (see also oral contraceptives) ethosuximide D Central Nervous etidocaine B1 Drugs Used in Local anaesthetics etonogestrel B3 Contraceptive Agents etoposide D Antineoplastic Agents etoricoxib C Musculoskeletal etravirine B1 Antimicrobials Antiviral etretinate X Drugs used in everolimus C Allergy and Immune ic exemestane C Antineoplastic Agents Hormonal antineoplastic exenatide C Endocrine Hypoglycaemic ezetimibe B3 Cardiovascular Hypolipidaemic factor IX (human) C Cardiovascular Haemostatic factor IX (r CHO) B2 Cardiovascular Haemostatic famciclovir B1 Antimicrobials Antiviral famotidine B1 Alimentary Hyperacidity, reflux, ulcers fampridine C Central Nervous felodipine C Cardiovascular Antihypertensives Calcium channel blockers fenfluramine B2 Metabolism Anorectic and weight reducing fenofibrate B3 Cardiovascular Hypolipidaemic fenoterol A Cardiovascular Adrenergic stimulants fenoterol A Respiratory Inhalational Bronchospasm relaxants fentanyl C Central Nervous ferric carboxymaltose B3 Blood and Haemopoietic Analgesics and Antipyretics (see also non-steroidal anti-inflammatory ) Opioid analgesics ferucarbotran B1 Diagnostic Agents Radiographic

17 Page 17 of 41 fexofenadine B2 Allergy and Immune fibrin B2 Cardiovascular Haemostatic fibrinogen B2 Cardiovascular Haemostatic fibronectin B2 Cardiovascular Haemostatic filgrastim B3 Blood and Haemopoietic finasteride X Drugs used in Haemopoietic Topical finasteride X Genitourinary Prostate hyperplasia fingolimod D Allergy and Immune flecainide B3 Cardiovascular Antiarrhythmics fleroxacin B3 Antimicrobials Antibiotics Quinolones flucloxacillin B1 Antimicrobials Antibiotics Penicillins fluconazole D Antimicrobials Antifungal (see also topical antifungals) flucytosine B3 Antimicrobials Antifungal (see also topical antifungals) fludarabine D Antineoplastic Agents Antibiotic cytotoxic fludrocortisone (systemic) C Endocrine Corticosteroids ic fludrocortisone (topical) A Endocrine Corticosteroids Topical flumazenil B3 Detoxifying Agents, Antidotes flumethasone A Endocrine Corticosteroids Topical flunisolide B3 Endocrine Corticosteroids Inhalation/intranasal flunitrazepam C Central Nervous Benzodiazepines fluocinolone A Endocrine Corticosteroids Topical fluocortolone A Endocrine Corticosteroids Topical fluorescein sodium B2 Ophthalmic Drugs fluorometholone B3 Ophthalmic Drugs fluorouracil D Antineoplastic Agents Antimetabolites fluoxetine C Central Nervous Selective serotonin reuptake inhibitors (SSRIs) fluoxymesterone D Endocrine Androgens and anabolic steroids flupenthixol C Central Nervous fluphenazine C Central Nervous flurazepam C Central Nervous flurbiprofen B2 Ophthalmic Drugs Benzodiazepines Phenothiazines fluticasone B3 Endocrine Corticosteroids Inhalation/intranasal fluticasone B3 Respiratory Inhalational Preventative aerosols and inhalations fluvastatin D Cardiovascular Hypolipidaemic

18 Page 18 of 41 fluvoxamine C Central Nervous folic acid A Blood and Haemopoietic folinic acid (leucovorin) A Blood and Haemopoietic Selective serotonin reuptake inhibitors (SSRIs) follicle stimulating hormone (recombinant human) B3 Endocrine Ovulation inducers Gonadotrophins follitropin alfa D Endocrine Pituitary hormones follitropin beta B2 Endocrine Pituitary hormones fomivirsen B2 Antimicrobials Antiviral fondaparinux C Cardiovascular Anticoagulants and thrombolytic fosamprenavir B3 Antimicrobials Antiviral fosaprepitant B2 Antineoplastic Agents Non-cytotoxic supportive therapy foscarnet B3 Antimicrobials Antiviral fosinopril D Cardiovascular Antihypertensives Angiotensin converting enzyme (ACE) inhibitors fotemustine D Antineoplastic Agents Alkylating framycetin D Antimicrobials Antibiotics Aminoglycosides frusemide C Cardiovascular Diuretics Thiazides, related diuretics and loop diuretics fulvestrant D Antineoplastic Agents Hormonal antineoplastic fusidic acid C Antimicrobials Antibiotics FVIII inhibitor bypassing fraction B2 Cardiovascular Haemostatic gabapentin B1 Central Nervous gadobenate B3 Diagnostic Agents Radiographic gadodiamide B3 Diagnostic Agents Radiographic gadofosveset B3 Diagnostic Agents Radiographic gadopentetate dimeglumine B2 Diagnostic Agents Radiographic gadoteridol B3 Diagnostic Agents Radiographic gadoversetamide B3 Diagnostic Agents Radiographic gadoxetate B3 Diagnostic Agents Radiographic galactose with palmitic acid B2 Diagnostic Agents Radiographic galantamine B1 Cholinergic and Anticholinergic Agents gallamine C Drugs Used in Neuromuscular blocking galsulfase B3 Metabolism Agents used for the treatment of metabolic disorders ganciclovir D Antimicrobials Antiviral ganirelix D Endocrine Pituitary inhibitors gatifloxacin B3 Antimicrobials Antibiotics Quinolones gefitinib C Antineoplastic Agents Tyrosine kinase inhibitors

19 Page 19 of 41 gelatin - succinylated B3 Cardiovascular gemcitabine D Antineoplastic Agents Antimetabolites gemeprost B3 Genitourinary Agents acting on the uterus gemfibrozil B3 Cardiovascular Hypolipidaemic gentamicin D Antimicrobials Antibiotics Aminoglycosides gestoden B3 Endocrine Progestogens (see also oral contraceptives) gestrinone D Endocrine Pituitary inhibitors glatiramer B1 Allergy and Immune glibenclamide C Endocrine Hypoglycaemic gliclazide C Endocrine Hypoglycaemic glimepiride C Endocrine Hypoglycaemic glipizide C Endocrine Hypoglycaemic glucagon B3 Detoxifying Agents, Antidotes glyceryl trinitrate B2 Cardiovascular Antiangina glyceryl trinitrate B2 Cardiovascular Vasodilators glycopyrrolate B2 Alimentary Antispasmodics glycopyrrolate B2 Cholinergic and Anticholinergic Agents golimumab C Allergy and immune gonadotrophin - human chorionic gonadotrophin - human menopausal A Endocrine Ovulation inducers Gonadotrophins C Endocrine Ovulation inducers Gonadotrophins goserelin D Antineoplastic Agents Hormonal antineoplastic goserelin D Endocrine Pituitary hormones granisetron B1 Central Nervous Antiemetics, antinauseants griseofulvin B3 Antimicrobials Antifungal (see also topical antifungals) guaiphenesin A Respiratory Expectorants and mucolytics guanethidine A Cardiovascular Antihypertensives haemophilus influenza type B vaccine B2 Vaccines Killed vaccines halcinonide A Endocrine Corticosteroids Topical haloperidol C Central Nervous halothane A Drugs Used in General anaesthetics Butyrophenones heparin C Cardiovascular Anticoagulants and thrombolytic hepatitis A vaccine B2 Vaccines Killed vaccines hepatitis B vaccine B2 Vaccines Killed vaccines hexamine A Genitourinary Urinary antiseptics homatropine B2 Ophthalmic Drugs

20 Page 20 of 41 hydralazine C Cardiovascular Antihypertensives hydrochlorothiazide C Cardiovascular Diuretics Thiazides, related diuretics and loop diuretics hydrocortisone A Endocrine Corticosteroids ic hydromorphone C Central Nervous hydroxychloroquine D Musculoskeletal Analgesics and Antipyretics (see also non-steroidal anti-inflammatory ) Antirheumatoid Opioid analgesics hydroxychloroquine (antimalarial) D Antimicrobials Antimalarials hydroxyprogesterone D Endocrine Progestogens (see also oral contraceptives) hydroxyquinoline A Drugs used in Topical antifungals, antiseptics (see also antifungal ) hydroxyurea D Antineoplastic Agents Antimetabolites hydroxyzine A Allergy and Immune hyoscine B2 Central Nervous Antiemetics, antinauseants hyoscine B2 Cholinergic and Anticholinergic Agents hyoscine hydrobromide B2 Central Nervous Antiemetics, antinauseants hyoscine methobromide A Cholinergic and Anticholinergic Agents hyoscine-n-butylbromide B2 Alimentary Antispasmodics hyoscine-n-butylbromide B2 Cholinergic and Anticholinergic Agents hyoscyamine B2 Alimentary Antidiarrhoeals hyoscyamine B2 Cholinergic and Anticholinergic Agents ibandronate B3 Endocrine Agents affecting calcium and bone metabolism Bisphosphonates ibuprofen C Musculoskeletal ibutilide B3 Cardiovascular Antiarrhythmics Icatibant C Cardiovascular idarubicin D Antineoplastic Agents Antibiotic cytotoxic idoxuridine (ophthalmic) B3 Ophthalmic Drugs idoxuridine (topical) B1 Drugs used in Topical antiviral idursulfase B2 Metabolism Agents used for the treatment of metabolic disorders ifosfamide D Antineoplastic Agents Alkylating iloprost B3 Cardiovascular Vasodilators imatinib D Antineoplastic Agents Tyrosine kinase inhibitors imiglucerase B2 Metabolism Agents used for the treatment of metabolic disorders imipenem with cilastatin B3 Antimicrobials Antibiotics

21 Page 21 of 41 imipramine C Central Nervous imiquimod B1 Drugs used in Topical antiviral Tricyclic antidepressants Indacaterol B3 Respiratory Inhalational Bronchospasm relaxants indapamide C Cardiovascular Diuretics Thiazides, related diuretics and loop diuretics indigo carmine B2 Genitourinary indinavir B3 Antimicrobials Antiviral indomethacin C Musculoskeletal infliximab C Allergy and Immune influenza vaccine (pandemic) B2 Vaccines Killed vaccines influenza vaccine (prepandemic) influenza vaccine (seasonal, AGRIPPAL S1TM) influenza vaccine (seasonal, except AGRIPPAL S1TM) influenza vaccine (seasonal, INTANZA) B2 Vaccines Killed vaccines B1 Vaccines Killed vaccines B2 Vaccines Killed vaccines B1 Vaccines Killed vaccines insulin - aspart A Endocrine Hypoglycaemic Insulins insulin - detemir B3 Endocrine Hypoglycaemic Insulins insulin - glargine B3 Endocrine Hypoglycaemic Insulins insulin - glulisine B3 Endocrine Hypoglycaemic Insulins insulin - lispro A Endocrine Hypoglycaemic Insulins interferon alpha-2a B3 Allergy and Immune interferon alpha-2b B3 Allergy and Immune interferon beta-1a D Allergy and Immune interferon beta-1b D Allergy and Immune interferon gamma-1b B3 Allergy and Immune iodixanol B1 Diagnostic Agents Radiographic iodoform with bismuth subnitrate D Drugs used in Topical antifungals, antiseptics (see also antifungal ) iomeprol B3 Diagnostic Agents Radiographic iopromide B2 Diagnostic Agents Radiographic ioversol B1 Diagnostic Agents Radiographic ipecacuanha A Respiratory Expectorants and mucolytics ipilimumab C Antineoplastic Agents Monoclonal antibodies ipratropium bromide B1 Respiratory Inhalational Bronchospasm relaxants irbesartan D Cardiovascular Antihypertensives Angiotensin II receptor antagonists and renin inhibitors

22 Page 22 of 41 irinotecan D Antineoplastic Agents iron polymaltose (oral) A Blood and Haemopoietic iron polymaltose (parenteral) A Blood and Haemopoietic iron sucrose (parenteral) B3 Blood and Haemopoietic isoconazole B2 Genitourinary Topical vaginal medication isoflurane B3 Drugs Used in General anaesthetics isoniazid A Antimicrobials Antituberculotics and antileprotics isoprenaline A Cardiovascular Adrenergic stimulants isoprenaline A Respiratory Inhalational Bronchospasm relaxants isosorbide dinitrate B1 Cardiovascular Antiangina isosorbide dinitrate B1 Cardiovascular Vasodilators isosorbide mononitrate B2 Cardiovascular Antiangina isotretinoin (systemic) X Drugs used in isotretinoin (topical) D Drugs used in ic Topical isoxsuprine C Cardiovascular Vasodilators isradipine C Cardiovascular Antihypertensives Calcium channel blockers itraconazole B3 Antimicrobials Antifungal (see also topical antifungals) ivabradine D Cardiovascular Antiangina ivermectin B3 Antimicrobials Anthelmintics Japanese encephalitis vaccine (inactivated) Japanese encephalitis vaccine (live, attenuated) Japanese encephalitis vaccine (live, recombinant) B1 Vaccines Killed vaccines B1 Vaccines Live attenuated virus vaccines B2 Vaccines Live attenuated virus vaccines kanamycin D Antimicrobials Antibiotics Aminoglycosides ketamine B3 Drugs Used in General anaesthetics ketoconazole B3 Antimicrobials Antifungal (see also topical antifungals) ketoprofen C Musculoskeletal ketorolac C Musculoskeletal ketotifen B1 Ophthalmic Drugs labetalol C Cardiovascular Beta-adrenergic blocking lacosamide B3 Central Nervous lamivudine B3 Antimicrobials Antiviral lamotrigine D Central Nervous lanreotide C Endocrine Pituitary hormones

23 Page 23 of 41 lansoprazole B3 Alimentary Hyperacidity, reflux, ulcers lanthanum B3 Detoxifying Agents, Antidotes lapatinib C Antineoplastic Agents Tyrosine kinase inhibitors laronidase B2 Metabolism Agents used for the treatment of metabolic disorders latanoprost B3 Ophthalmic Drugs laureth B3 Cardiovascular leflunomide X Allergy and Immune lenalidomide X Allergy and Immune lenograstim B3 Blood and Haemopoietic Haemopoietic lepirudin B3 Cardiovascular Anticoagulants and thrombolytic lercanidipine C Cardiovascular Antihypertensives Calcium channel blockers letrozole D Antineoplastic Agents Hormonal antineoplastic leuprorelin D Antineoplastic Agents Hormonal antineoplastic levamisole B3 Allergy and Immune levetiracetam B3 Central Nervous levobunolol C Cardiovascular Beta-adrenergic blocking levobunolol (ophthalmic) C Ophthalmic Drugs levobupivacaine B3 Drugs Used in levocabastine B3 Allergy and Immune Local anaesthetics levocabastine (ophthalmic) B3 Ophthalmic Drugs levocetirizine B2 Allergy and Immune levodopa B3 Central Nervous Antiparkinson levonorgestrel B3 Contraceptive Agents Oral contraceptives lignocaine A Cardiovascular Antiarrhythmics lignocaine A Drugs Used in Local anaesthetics linagliptin B3 Endocrine Hypoglycaemic lincomycin A Antimicrobials Antibiotics lindane B3 Drugs used in Topical antiparasitics linezolid B3 Antimicrobials Antibiotics liothyronine A Endocrine Thyroid hormones liraglutide (rys) B3 Endocrine Hypoglycaemic lisinopril D Cardiovascular Antihypertensives Angiotensin converting enzyme (ACE) inhibitors lithium salts D Central Nervous

24 Page 24 of 41 lodoxamide trometamol B1 Ophthalmic Drugs lomustine D Antineoplastic Agents Alkylating loperamide B3 Alimentary Antidiarrhoeals lopinavir with ritonavir B3 Antimicrobials Antiviral loracarbef B1 Antimicrobials Antibiotics Cephalosporins loratadine B1 Allergy and Immune lorazepam C Central Nervous Benzodiazepines losartan D Cardiovascular Antihypertensives Angiotensin II receptor antagonists and renin inhibitors lumiracoxib C Musculoskeletal lutropin alfa B3 Endocrine Pituitary hormones lypressin B2 Endocrine Antidiuretics maldison (malathion) B2 Drugs used in Topical antiparasitics mannitol B2 Cardiovascular maraviroc B1 Antimicrobials Antiviral mazindol B3 Metabolism Anorectic and weight reducing measles vaccine B2 Vaccines Live attenuated virus vaccines measles-mumps vaccine B2 Vaccines Live attenuated virus vaccines measles-mumps-rubella vaccine measles-mumps-rubellavaricella vaccine B2 Vaccines Live attenuated virus vaccines B2 Vaccines Live attenuated virus vaccines mebendazole B3 Antimicrobials Anthelmintics mebeverine B2 Alimentary Antispasmodics medroxyprogesterone (IM contraceptive dose) A Contraceptive Agents medroxyprogesterone (oral & SC high dose) medroxyprogesterone (oral and IM high dose) D Endocrine Progestogens (see also oral contraceptives) D Antineoplastic Agents Hormonal antineoplastic mefenamic acid C Musculoskeletal mefloquine B3 Antimicrobials Antimalarials mefruside C Cardiovascular Diuretics Thiazides, related diuretics and loop diuretics megestrol D Endocrine Progestogens (see also oral contraceptives) melatonin B3 Central Nervous meloxicam C Musculoskeletal Hypnotics and sedatives melphalan D Antineoplastic Agents Alkylating memantine B2 Central Nervous

25 Page 25 of 41 meningococcal vaccine (oligosaccharide) meningococcal vaccine (polysaccharide) B1 Vaccines killed vaccines B2 Vaccines Killed vaccines mepivacaine A Drugs Used in meprobamate C Central Nervous Local anaesthetics Hypnotics and sedatives mercaptopurine D Antineoplastic Agents Antimetabolites meropenem B2 Antimicrobials Antibiotics mesalazine C Alimentary Antidiarrhoeals mesna B1 Antineoplastic Agents Non-cytotoxic supportive therapy mesterolone X Endocrine Androgens and anabolic steroids mestranol B3 Endocrine Oestrogens (see also oral contraceptives) metaraminol C Cardiovascular Adrenergic stimulants metformin C Endocrine Hypoglycaemic methacycline D Antimicrobials Antibiotics Tetracyclines methadone C Agents used in dependency states methadone C Central Nervous methdilazine B2 Allergy and Immune Analgesics and Antipyretics (see also non-steroidal anti-inflammatory ) Opioid analgesics methenolone D Endocrine Androgens and anabolic steroids methocarbamol B2 Musculoskeletal methohexitone B2 Drugs Used in Muscle relaxants General anaesthetics methotrexate D Antineoplastic Agents Antimetabolites methoxsalen B2 Drugs used in Topical methoxy polyethylene glycolepoetin beta B3 Blood and Haemopoietic Haemopoietic methoxyflurane C Drugs Used in methsuximide D Central Nervous General anaesthetics methyclothiazide C Cardiovascular Diuretics Thiazides, related diuretics and loop diuretics methyl aminolevulinate B2 Antineoplastic Agents methyldopa A Cardiovascular Antihypertensives methylene blue D Blood and Haemopoietic methylnaltrexone B1 Central Nervous methylphenidate B2 Central Nervous methylphenobarbitone D Central Nervous CNS stimulants

26 Page 26 of 41 methylprednisolone A Endocrine Corticosteroids ic methylprednisolone aceponate C Endocrine Corticosteroids Topical methyltestosterone D Endocrine Androgens and anabolic steroids methysergide C Cardiovascular Antimigraine preparations metoclopramide A Central Nervous Antiemetics, antinauseants metolazone C Cardiovascular Diuretics Thiazides, related diuretics and loop diuretics metoprolol C Cardiovascular Beta-adrenergic blocking metronidazole B2 Antimicrobials Antibiotics metyrapone B2 Diagnostic Agents Pituitary-adrenal response test mexiletine B1 Cardiovascular Antiarrhythmics mezlocillin B1 Antimicrobials Antibiotics Penicillins mianserin B2 Central Nervous miconazole A Drugs used in Topical antifungals, antiseptics (see also antifungal ) Tetracyclic antidepressants miconazole A Genitourinary Topical vaginal medication midazolam C Central Nervous Benzodiazepines miglitol B3 Endocrine Hypoglycaemic miglustat D Metabolism Agents used for the treatment of metabolic disorders milnacipran B3 Central Nervous milrinone B3 Cardiovascular Cardiac inotropic minocycline D Antimicrobials Antibiotics Tetracyclines minoxidil C Cardiovascular Antihypertensives mirtazapine B3 Central Nervous misoprostol X Alimentary Hyperacidity, reflux, ulcers mitomycin D Antineoplastic Agents Antibiotic cytotoxic mitozantrone D Antineoplastic Agents Antibiotic cytotoxic mivacurium B2 Drugs Used in moclobemide B3 Central Nervous modafinil B3 Central Nervous molgramostim B3 Blood and Haemopoietic Neuromuscular blocking CNS stimulants Haemopoietic mometasone B3 Endocrine Corticosteroids Topical montelukast B1 Respiratory moroctocog alfa (factor VIII - rch) B2 Cardiovascular Haemostatic morphine C Central Nervous Analgesics and Antipyretics (see also non-steroidal anti-inflammatory ) Opioid analgesics

27 Page 27 of 41 moxifloxacin B3 Antimicrobials Antibiotics Quinolones moxonidine B3 Cardiovascular Antihypertensives mumps vaccine B2 Vaccines Live attenuated virus vaccines mupirocin B1 Antimicrobials Antibiotics mustine D Antineoplastic Agents Alkylating mycophenolate mofetil D Allergy and Immune mycophenolic acid D Allergy and Immune nabumetone C Musculoskeletal nadroparin C Cardiovascular Anticoagulants and thrombolytic nafarelin D Endocrine Pituitary hormones nalidixic acid A Antimicrobials Antibiotics naloxone B1 Detoxifying Agents, Antidotes naltrexone B3 Agents used in dependency states nandrolone D Endocrine Androgens and anabolic steroids naproxen C Musculoskeletal naratriptan B3 Cardiovascular Antimigraine preparations natalizumab C Allergy and Immune nateglinide C Endocrine Hypoglycaemic nebivolol C Cardiovascular Beta-adrenergic blocking nedocromil B1 Respiratory Inhalational Preventative aerosols and inhalations nefazodone B3 Central Nervous nelfinavir B2 Antimicrobials Antiviral neomycin D Antimicrobials Antibiotics Aminoglycosides neostigmine B2 Drugs Used in Myasthenia Gravis netilmicin D Antimicrobials Antibiotics Aminoglycosides nevirapine B3 Antimicrobials Antiviral nicardipine C Cardiovascular Antihypertensives Calcium channel blockers nicorandil B3 Cardiovascular Antiangina nicotine D Agents used in dependency states nicotinic acid B2 Cardiovascular Hypolipidaemic nicotinic acid B2 Cardiovascular Vasodilators nicotinic acid B2 Vitamins nicotinyl alcohol B1 Cardiovascular Vasodilators nifedipine C Cardiovascular Antihypertensives Calcium channel blockers nilotinib D Antineoplastic Agents Tyrosine kinase inhibitors

28 Page 28 of 41 nimodipine C Cardiovascular Antihypertensives Calcium channel blockers nisoldipine C Cardiovascular Antihypertensives Calcium channel blockers nitisinone B3 Metabolism Agents used for the treatment of metabolic disorders nitrazepam C Central Nervous Benzodiazepines nitric oxide B2 Cardiovascular Vasodilators nitrofurantoin (short term therapy) A Antimicrobials Antibiotics nitrous oxide A Drugs Used in General anaesthetics nizatidine B3 Alimentary Hyperacidity, reflux, ulcers nomegestrol with oestradiol B3 Contraceptive Agents nonacog alfa (rch) B2 Cardiovascular Haemostatic nonoxinol 9 A Contraceptive Agents Vaginal spermicides norelgestromin with ethinyloestradiol B3 Contraceptive Agents norethisterone D Endocrine Progestogens (see also oral contraceptives) norfloxacin B3 Antimicrobials Antibiotics Quinolones nortriptyline C Central Nervous Tricyclic antidepressants nystatin A Antimicrobials Antifungal (see also topical antifungals) nystatin A Genitourinary Topical vaginal medication octocog alfa (factor VIII - rch) B2 Cardiovascular Haemostatic octoxinol A Contraceptive Agents Vaginal spermicides octreotide C Endocrine Pituitary hormones oestradiol B1 Endocrine Oestrogens (see also oral contraceptives) oestriol B1 Endocrine Oestrogens (see also oral contraceptives) oestrogens conjugated D Endocrine Oestrogens (see also oral contraceptives) oestrone B1 Endocrine Oestrogens (see also oral contraceptives) ofatumumab C Antineoplastic Agents Monoclonal antibodies ofloxacin B3 Antimicrobials Antibiotics Quinolones olanzapine C Central Nervous olmesartan D Cardiovascular Antihypertensives Angiotensin II receptor antagonists and renin inhibitors olopatadine B1 Ophthalmic Drugs olsalazine C Alimentary Antidiarrhoeals omalizumab B1 Respiratory omega-3-acid ethyl esters 90 B1 Cardiovascular Hypolipidaemic omeprazole B3 Alimentary Hyperacidity, reflux, ulcers

29 Page 29 of 41 ondansetron B1 Central Nervous Antiemetics, antinauseants opium alkaloids and derivatives A Respiratory Antitussives oral contraceptives, combined B3 Contraceptive Agents Oral contraceptives orciprenaline A Cardiovascular Adrenergic stimulants orciprenaline A Respiratory Inhalational Bronchospasm relaxants orlistat B1 Metabolism Anorectic and weight reducing ornipressin B3 Cardiovascular Haemostatic orphenadrine B2 Musculoskeletal Muscle relaxants oseltamivir B1 Antimicrobials Antiviral oxaliplatin D Antineoplastic Agents oxandrolone D Endocrine Androgens and anabolic steroids oxazepam C Central Nervous oxcarbazepine D Central Nervous Benzodiazepines oxpentifylline B1 Cardiovascular oxprenolol C Cardiovascular Beta-adrenergic blocking oxybuprocaine D Ophthalmic Drugs oxybutynin B1 Genitourinary Bladder function disorders oxycodone C Central Nervous Analgesics and Antipyretics (see also non-steroidal anti-inflammatory ) Opioid analgesics oxymetholone D Endocrine Androgens and anabolic steroids oxytetracycline D Antimicrobials Antibiotics Tetracyclines oxytocin A Genitourinary Agents acting on the uterus paclitaxel D Antineoplastic Agents Antimetabolites palifermin B3 Antineoplastic Agents Non-cytotoxic supportive therapy paliperidone C Central Nervous palonosetron B1 Central Nervous Antiemetics, antinauseants pamidronate B3 Endocrine Agents affecting calcium and bone metabolism Bisphosphonates pancuronium B2 Drugs Used in Neuromuscular blocking panitumumab C Antineoplastic Agents Monoclonal antibodies pantoprazole B3 Alimentary Hyperacidity, reflux, ulcers papaveretum C Central Nervous Analgesics and Antipyretics (see also non-steroidal anti-inflammatory ) Opioid analgesics papaverine A Cardiovascular Vasodilators papaverine A Cholinergic and Anticholinergic Agents papillomavirus vaccine B2 Vaccines Killed vaccines