Anti-tick vaccines: A potential tool for control of the blacklegged ticks and other ticks feeding on whitetailed deer
|
|
- Jessie Brown
- 5 years ago
- Views:
Transcription
1 Anti-tick vaccines: A potential tool for control of the blacklegged ticks and other ticks feeding on whitetailed deer Andrew Y. Li USDA-ARS Invasive Insect Biocontrol and Behavior Laboratory (IIBBL) Beltsville, MD Integrated Tick Management Symposium: Solving America s Tick-Borne Disease Problem May 16-17, 2016 Washington, D.C.
2 Life cycle of Ixodes scapularis Tick control measurers: Dr. Rich Gary, Ohio Department of Health Area spray of pesticides: synthetic- versus bio-pesticides Host-targeted control (immature ticks): Tick tube, Bait box Host-targeted control (adult ticks): 4-Poster deer feeder Anti-tick vaccines for use on host animals (deer, mice)
3 Commercial Anti-tick vaccines: TickGARD (Australia) Gavac (Cuba) Both use recombinant Bm86 tick protein. Registration / commercialization in Australia and Latin American countries Continued field use in the following decade. Dr. Peter Willadsen Cattle tick Boophilus microplus Dr. Manuel Rodriguez Valle Dr. Jose de la Fuente
4 How does Bm86 work? Bm86 is a glycoprotein associated with midgut of the cattle tick, Rhipicephalus (Boophilus) microplus. Immunization of cattle with the recombinant Bm86 protein triggers immune response of cattle. Antibody-antigen interaction in the midgut lumen of feeding ticks causes damage to midgut membrane, leading to tick mortality, reduced female size, and reduced fecundity (# eggs laid, egg hatching rate). Cuba ( ) Use of GAVAC led to 87% reduction in number of acaricide use. de la Fuente & Kocan, 2014
5 Benefits of using Anti-tick vaccines: Mexico introduced in The number of acaricide applications was reduced from 24 to 7-8 / year (67% reduction). - More use of GAVAC to help acaricide resistance issues Tick Free R. annulatus R. microplus Veracruz, Mexico
6 Efficacy evaluation of the Bm86-based anti-tick vaccine Gavac against Texas outbreak strains of Rhipicephalus microplus and R. annulatus (Miller et al. 2012) Efficacy of Gavac against cattle fever ticks in Texas: - R. annulatus: 99.9% - R. microplus: 30%
7 Integrated strategy for sustainable cattle fever tick eradication: Possibility of use of anti-tick vaccine as a component of integrated cattle fever tick eradication. In 2016, Texas Animal Health Commission amended its roles to include use of fever tick vaccine in quarantine areas.
8 Other tick antigens: Antigen Tick species Reference Bm86 tick gut protein Rhipicephalus microplus Willadsen et al. (1988) BA86 tick gut protein Rhipicephalus annulatus Canales et al. (2008) Bm96 homolog of Bm86 Rhipicephalus microplus García-García et al. (2000) de la Fuente and Kocan (2003) HAA86 ortholog of Bm86 Hyalomma anatolicum anatolicum Azhahianambi et al. (2009) Jeyabal et al. (2010) 64TRP, Salp15 tick salivary proteins Ixodes scapularis Anguita et al. (2002) Salp25D, thrf Ixodes ricius Trimnell et al. (2002) TSLPI Dai et al. (2001, 2010) Schuijt et al. (2011) 64P cement protein Rhipicephalus appendicultus Trimnell et al. (2002) Ferritins iron-storage protein in Ixodes ricinus Kopacek et al. (2003) gut secreted into Hajduse et al. (2009) hemolymph Subolesin ortholog of insect akirins Ixodes scapularis Amazan et al. (2003, 2005) Aquoporin water channel protein Rhipicephalus microplus Guerrero et al. (2014)
9 Subolesin Subolesin was discovered as a tick protective antigen in a mouse model of the blacklegged tick I. scapularis (Almazan et al., 2003; 2005a,b). Subolesin is the ortholog protein of insect akirin (AKR) that has a broad function in transcription, immunity, gene expression, development and physiology (de la Fuente et al., 2006, 2011, 2015). Recombinant protein was expressed in E. coli, and was used to vaccinated mice, rabbit and sheep against infestation of larvae, nymphs and adults of I. scapularis. Results of vaccination with recombinant subolesin on different development stages of I. scapularis. Stage Host Effects Larva mouse Reducing molting to nymphs by 71% nymph rabbit Reducing #of engorged engorged nymphs by 35% adult rabbit immune sera Caused 25% mortality (capillary feeding) Reduce weight gain by 35% PAGE of recombinant 4D8 protein (Subolesin) D. Variabilis nymphes fed on 4D8-vaccinated rabbit. Also effective against other tick species, including: - American dog tick, D. Variabilisis - Lone star tick, A. americanum - Rhipicephalus spp. Almazan et al Vaccine 23: De la Fuente et al Transbound Emerg. Dis. 60:
10 Discovery of aquaporin gene in R. microplus. cdna expression of RmAQP1 in Pichia pastoris to produce the recombinant protein. Cattle vaccination trials in Brazil
11
12
13 Vaccination of livestock versus wildlife Livestock cattle, sheep, etc. Subcutaneous injection Intra-nasal administration Oral vaccine cattlebreeders.org Wildlife such as whitetailed deer Needle injection? Dart gun Oral vaccine Oral Rabbies Vaccine GonaCon Birth Control for Deer Humane Society of the United States
14 USDA -ARS National Animal Disease Center Ames, IA USDA-APHIS National Wildlife Center Fort Collins, CO Oral Vaccine of white-tailed deer with Mycobacterium bovis Bacillus Calmette-Guerin (BCG) to prevent the transmission of bovine tuberculosis to other deer and cattle
15 Cattle Tick Vaccine Consortium (CATVAC) Working pipeline proposed by CATVAC for development of effective vaccines for cattle tick control A meeting sponsored by the Bill & Melinda Gates Foundation was held at the Avanti Hotel, Mohammedia, Morocco. July 14 15, The meeting resulted in the formation of the Cattle Tick Vaccine Consortium (CATVAC).
16 European approach toward solving ticks and tick-borne disease affecting humans, animals and wildlife ANTIDotE: ANti-tick vaccines to prevent TIck-borne Diseases in Europe Ixodes ricinus Sprong et al Parasites & Vectors 7:77.
17 Sprong et al Parasites & Vectors 7:77. Call to form a similar Anti-tick Vaccine Consortium in the U.S. Collaboration among researchers to facilitate research progress. Government, university, industry entities and non-profit organizations. Focusing on tick species and pathogens affecting human health. Existing and new antigens. in vitro and in vivo efficacy trials. Oral formulations for wildlife (whitetailed deer & whitefooted mouse) Funding for the work: - Industry? - Private foundations / Nonprofit organizations? - Government agencies?
18 Summary Two commercial anti-tick vaccines have been successfully developed to control cattle ticks. The Bm86-based vaccine can achieve near 100% efficacy against R. annulatus ticks. There are a number of promising anti-tick antigens that have been evaluated against several different tick species, including I. scapularis, resulting in 60-70% efficacy. Anti-tick vaccines can potentially be a useful tool for Integrated Tick Management for control of blacklegged ticks on deer and rodents. Many challenges exist for development of such vaccine products. Call for forming a anti-tick research group in the U.S. to facilitate novel antigen discovery and product development. Funding for anti-tick vaccine research by federal government is required in order to make substantial progress toward anti-tick vaccine products that can help control ticks and reduce the risk of tick-borne diseases, particularly Lyme disease.
19 Acknowledgments USDA-ARS-KBUSLIRL Felix Guerrero Adalberto Perez de Leon USDA-ARS Area-wide Pest Management program USDA-NIFA Northeast IPM Center Beltsville Agricultural Center
1. INTRODUCTION. Ticks are obligate haematophagous ectoparasites with. worldwide distribution and they have a significant impact on human
1. INTRODUCTION Ticks are obligate haematophagous ectoparasites with worldwide distribution and they have a significant impact on human and animal health. A total of ~850 tick species have been catalogued
More informationsoft ticks hard ticks
Ticks Family Argasidae soft ticks Only 4 genera of Argasidae Argas, Ornithodoros, Otobius (not covered) and Carios (not covered) Family Ixodidae hard ticks Only 4 genera of Ixodidae covered because of
More informationAbout Ticks and Lyme Disease
About Ticks and Lyme Disease Ticks are small crawling bugs in the spider family. They are arachnids, not insects. There are hundreds of different kinds of ticks in the world. Many of them carry bacteria,
More informationWes Watson and Charles Apperson
Wes Watson and Charles Apperson Ticks are not insects! Class Acarina Order Parasitiformes Family Argasidae soft ticks (5 genera) Family Ixodidae hard ticks (7 genera) Genus Dermacentor 30 species Amblyomma
More informationTOPICAL ACARICIDES DEER
TOPICAL ACARICIDES DEER Kirby C. Stafford III, Ph.D. Chief Scientist, State Entomologist CT Agricultural Experiment Station New Haven, CT Tick IPM Symposium Washington, D.C. May 16, 2016 PROBLEMS ASSOCIATED
More informationEXHIBIT E. Minimizing tick bite exposure: tick biology, management and personal protection
EXHIBIT E Minimizing tick bite exposure: tick biology, management and personal protection Arkansas Ticks Hard Ticks (Ixodidae) Lone star tick - Amblyomma americanum Gulf Coast tick - Amblyomma maculatum
More informationSlide 1. Slide 2. Slide 3
1 Exotic Ticks Amblyomma variegatum Amblyomma hebraeum Rhipicephalus microplus Rhipicephalus annulatus Rhipicephalus appendiculatus Ixodes ricinus 2 Overview Organisms Importance Disease Risks Life Cycle
More informationMichele Stanton, M.S. Kenton County Extension Agent for Horticulture. Asian Longhorned Beetle Eradication Program Amelia, Ohio
Michele Stanton, M.S. Kenton County Extension Agent for Horticulture Asian Longhorned Beetle Eradication Program Amelia, Ohio Credits Dr. Glen Needham, Ph.D., OSU Entomology (retired), Air Force Medical
More informationOn People. On Pets In the Yard
*This information is provided by the Center for Disease Control as part of the public domain. Avoiding Ticks Reducing exposure to ticks is the best defense against Lyme disease, Rocky Mountain spotted
More informationIxodes affinis, an enzootic vector of Borrelia burgdorferi s.s., newly discovered and common in eastern North Carolina
Ixodes affinis, an enzootic vector of Borrelia burgdorferi s.s., newly discovered and common in eastern North Carolina Bruce A. Harrison PhD Public Health Pest Management Winston-Salem, NC Acknowledgments
More informationThe Blacklegged tick (previously called the Deer tick ) or Ixodes scapularis,
Ticks with black legs and the discovery of Ixodes affinis in North Carolina Bruce A. Harrison PhD Public Health Pest Management Winston Salem, NC Acknowledgments Walker Rayburn Jr., Perquimans County PHPM
More informationUNDERSTANDING THE TRANSMISSION OF TICK-BORNE PATHOGENS WITH PUBLIC HEALTH IMPLICATIONS
UNDERSTANDING THE TRANSMISSION OF TICK-BORNE PATHOGENS WITH PUBLIC HEALTH IMPLICATIONS A. Rick Alleman, DVM, PhD, DABVP, DACVP Lighthouse Veterinary Consultants, LLC Gainesville, FL Tick-transmitted pathogens
More informationTicks and Mosquitoes: Should they be included in School IPM programs? Northeastern Center SIPM Working Group July 11, 2013 Robert Koethe EPA Region 1
Ticks and Mosquitoes: Should they be included in School IPM programs? Northeastern Center SIPM Working Group July 11, 2013 Robert Koethe EPA Region 1 1 Discussion topics Overview on ticks and mosquitoes
More informationKnow Thy Enemy. Enemy #1. Tick Disease. Tick Disease. Integrated Pest Management. Integrated Pest Management 7/7/14
Enemy #1 Know Thy Enemy Understanding Ticks and their Management Matt Frye, PhD NYS IPM Program mjf267@cornell.edu www.nysipm.cornell.edu 300,000 cases of Lyme Disease #1 vector- borne disease in US http://animals.howstuffworks.com/arachnids/mite-
More informationThe Essentials of Ticks and Tick-borne Diseases
The Essentials of Ticks and Tick-borne Diseases Presenter: Bobbi S. Pritt, M.D., M.Sc. Director, Clinical Parasitology Laboratory Co-Director, Vector-borne Diseases Laboratory Services Vice Chair of Education
More informationThree Ticks; Many Diseases
Three Ticks; Many Diseases Created By: Susan Emhardt-Servidio May 24, 2018 Rutgers NJAES Cooperative Extension NJAES is NJ Agricultural Experiment Station Extension mission is to bring research based information
More informationUnderstanding Ticks, Prevalence and Prevention. Tim McGonegal, M.S. Branch Chief Mosquito & Forest Pest Management Public Works
Understanding Ticks, Prevalence and Prevention Tim McGonegal, M.S. Branch Chief Mosquito & Forest Pest Management Public Works Outline Brief overview of MFPM program Tick Biology Types of ticks and disease
More informationDr. Erika T. Machtinger, Assistant Professor of Entomology Joyce Sakamoto, Research Associate The Pennsylvania State University.
Testimony for the Joint Hearing Senate Health & Human Services Committee and Senate Aging and Youth Committee Topic: Impact of Lyme Disease on the Commonwealth and Update on Lyme Disease Task Force Report
More informationTicks and Lyme Disease
Ticks and Lyme Disease Get Tick Smart Know the bug Know the bite Know what to do Know the Bug Ticks are external parasites Arachnid family Feed on mammals and birds Found Worldwide Two groups hard and
More informationWhat are Ticks? 4/22/15. Typical Hard Tick Life Cycle. Ticks of the Southeast The Big Five and Their Management
Ticks of the Southeast The Big Five and Their Management LT Jeff Hertz, MSC, USN PhD Student, Entomology and Nematology Dept., University of Florida What are Ticks? Ticks are MITES.really, really ig mites.
More informationWEST WHITELAND TOWNSHIP PUBLIC SERVICES COMMISSION
WEST WHITELAND TOWNSHIP PUBLIC SERVICES COMMISSION Monthly Meeting Agenda Wednesday, May 2, 2018 at 6:30 p.m. Call to Order Pledge of Allegiance Public Comment Review of Minutes April 4, 2018 Announcements
More informationTEMPORAL AND SPATIAL DISTRIBUTION OF THE BLACK-LEGGED TICK, IXODES SCAPULARIS, IN TEXAS AND ITS ASSOCIATION WITH CLIMATE VARIATION
TEMPORAL AND SPATIAL DISTRIBUTION OF THE BLACK-LEGGED TICK, IXODES SCAPULARIS, IN TEXAS AND ITS ASSOCIATION WITH CLIMATE VARIATION An Undergraduate Research Scholars Thesis By JOSHUA SANTELISES Submitted
More informationThe Ecology of Lyme Disease 1
The Ecology of Lyme Disease 1 What is Lyme disease? Lyme disease begins when a tick bite injects Lyme disease bacteria into a person's blood. Early symptoms of Lyme disease usually include a bull's-eye
More informationINTEGRATED TICK MANAGEMENT IN 2016
INTEGRATED TICK MANAGEMENT IN 2016 Kirby C. Stafford III, Ph.D. Chief Scientist, State Entomologist CT Agricultural Experiment Station New Haven, CT Tick IPM Symposium Washington, D.C. May 16, 2016 Skip
More informationSOLUTIONS TO ANIMAL PEST CONTROL STUDY QUESTIONS For the TDA Commercial/Non-Commercial Exam
1 SOLUTIONS TO ANIMAL PEST CONTROL STUDY QUESTIONS For the TDA Commercial/Non-Commercial Exam INSTRUCTIONS: As you study through the text, look for the answers to the following questions and mark them
More informationTick bite prevention and control
Tick bite prevention and control Howard S. Ginsberg, Ph.D. USGS Patuxent Wildlife Research Center Coastal Field Station, Woodward Hall PLS University of Rhode Island Kingston, RI 2881 USA hginsberg@usgs.gov
More informationFree-Ranging Wildlife. Biological Risk Management for the Interface of Wildlife, Domestic Animals, and Humans. Background Economics
Biological Risk Management for the Interface of Wildlife, Domestic Animals, and Humans Free-Ranging Wildlife This presentation concerns free-ranging birds and mammals John R. Fischer, DVM, PhD Southeastern
More informationEcology of RMSF on Arizona Tribal Lands
Ecology of RMSF on Arizona Tribal Lands Tribal Vector Borne Disease Meeting M. L. Levin Ph.D. Medical Entomology Laboratory Centers for Disease Control mlevin@cdc.gov Rocky Mountain Spotted Fever Disease
More informationTicks, Tick-borne Diseases, and Their Control 1. Ticks, Tick-Borne Diseases and Their Control. Overview. Ticks and Tick Identification
Ticks, Tick-Borne Diseases and Their Control Jeff N. Borchert, MS ORISE Research Fellow Bacterial Diseases Branch Division of Vector-Borne Infectious Diseases Centers for Disease Control and Prevention
More informationElizabeth Gleim, PhD. North Atlantic Fire Science Exchange April 2018
Elizabeth Gleim, PhD North Atlantic Fire Science Exchange April 2018 Ticks & Tick-borne Pathogens of the Eastern United States Amblyomma americanum AKA lone star tick Associated Diseases: Human monocytic
More informationANIMAL PEST CONTROL Study Questions to help you prepare for the TDA Commercial/Non-Commercial Exam
1 ANIMAL PEST CONTROL Study Questions to help you prepare for the TDA Commercial/Non-Commercial Exam INSTRUCTIONS: As you study through the text, look for the answers to the following questions and mark
More informationCOMMITTEE FOR VETERINARY MEDICINAL PRODUCTS
The European Agency for the Evaluation of Medicinal Products Veterinary Medicines and Information Technology EMEA/CVMP/005/00-FINAL-Rev.1 COMMITTEE FOR VETERINARY MEDICINAL PRODUCTS GUIDELINE FOR THE TESTING
More informationTopics. Ticks on dogs in North America. Ticks and tick-borne diseases: emerging problems? Andrew S. Peregrine
Ticks and tick-borne diseases: emerging problems? Andrew S. Peregrine E-mail: aperegri@ovc.uoguelph.ca Topics Ticks on dogs in Ontario and the pathogens they transmit? Should dogs be routinely screened
More informationEvaluation of Three Commercial Tick Removal Tools
Acarology Home Summer Program History of the Lab Ticks Removal Guidelines Removal Tools Tick Control Mites Dust Mites Bee Mites Spiders Entomology Biological Sciences Ohio State University Evaluation of
More informationLyme Disease in Ontario
Lyme Disease in Ontario Hamilton Conservation Authority Deer Management Advisory Committee October 6, 2010 Stacey Baker Senior Program Consultant Enteric, Zoonotic and Vector-Borne Disease Unit Ministry
More informationFertility Control for Grey Squirrels : what do the next 5 years look like? Giovanna Massei National Wildlife Management Centre APHA
Fertility Control for Grey Squirrels : what do the next 5 years look like? Giovanna Massei National Wildlife Management Centre APHA RSST, UK Squirrel Accord and Royal Forestry Society Sand Hutton, 19 October
More informationOld Dominion University Tick Research Update Chelsea Wright Department of Biological Sciences Old Dominion University
Old Dominion University Tick Research Update 2014 Chelsea Wright Department of Biological Sciences Old Dominion University Study Objectives Long-term study of tick population ecology in Hampton Roads area
More informationTick Surveillance in Loudoun County, VA Spring Lauren Lochstampfor Andy Lima VMCA, February 12, 2014
Tick Surveillance in Loudoun County, VA Spring 2013 Lauren Lochstampfor Andy Lima VMCA, February 12, 2014 Introduction High incidence of Lyme in Loudoun County, VA 2010 223 cases 2011 261 cases (18% of
More informationThe Business Case for Greater Investment in Tick IPM
The Business Case for Greater Investment in Tick IPM Thomas A. Green, Ph.D., CCA President Harnessing marketplace power to improve health, environment and economics www.ipminstitute.org Whole Foods Market
More informationLyme Disease in Vermont. An Occupational Hazard for Birders
Lyme Disease in Vermont An Occupational Hazard for Birders How to Prevent Lyme Disease 2 Lyme Disease is a Worldwide Infection Borrelia burgdoferi B. afzelii; and B. garinii www.thelancet.com Vol 379 February
More information2/12/14 ESTABLISHING A VECTOR ECOLOGY SITE TO UNDERSTAND TICK- BORNE DISEASES IN THE SOUTHEASTERN UNITED STATES LIFECYCLE & TRANSMISSION
2/12/14 ESTABLISHING A VECTOR ECOLOGY SITE TO UNDERSTAND TICK- BORNE DISEASES IN THE SOUTHEASTERN UNITED STATES Becky Trout Fryxell, Ph.D. Assistant Professor of Medical & Veterinary Entomol. Department
More informationGeographic and Seasonal Characterization of Tick Populations in Maryland. Lauren DiMiceli, MSPH, MT(ASCP)
Geographic and Seasonal Characterization of Tick Populations in Maryland Lauren DiMiceli, MSPH, MT(ASCP) Background Mandated reporting of human tick-borne disease No statewide program for tick surveillance
More informationRole of Veterinary Technicians in Regulatory Agencies. Alyson Boswell, BS, RVT Animal Health Technician USDA APHIS VS District 1 - Virginia
Role of Veterinary Technicians in Regulatory Agencies Alyson Boswell, BS, RVT Animal Health Technician USDA APHIS VS District 1 - Virginia Regulatory Medicine - Not focused on individual animals - Focused
More informationInnovation in Action. Passion to innovate. Global Conference on Sustainable Beef. Power to change. Science for a better life ///////////
Global Conference on Sustainable Beef Innovation in Action Passion to innovate Power to change /////////// Dr Zsolt Szeidemann, Beef Species Team 11 Oct 2018 Science for a better life 150 years of innovation
More informationCONTROL TICKS THAT MAY CARRY LYME DISEASE
AN AID TO CONTROL TICKS THAT MAY CARRY LYME DISEASE 1 Welcome to a new level of tick protection! For over 15 years, Thermacell has provided top-rated backyard mosquito protection. Now, we re proud to introduce
More informationTicks Ticks: what you don't know
Ticks Ticks: what you don't know Michael W. Dryden DVM, MS, PhD, DACVM (parasitology) Department of Diagnostic Medicine/Pathobiology Kansas State University, Manhattan KS While often the same products
More informationTHE POWER OF 3 IN ACTION READY TO SHINE. The Flea and Tick Control with the POWER OF 3.
THE POWER OF 3 IN ACTION READY TO SHINE. The Flea and Tick Control with the POWER OF 3 www.frontline.com TOPICALS WHY DO PET OWNERS CHOOSE TOPICAL FLEA AND TICK CONTROL? Value: Results: Flea and tick control
More informationIncreased Tick Prevalence: The Battleground Shifts with More Pets at Risk. July 18-31, 2011
Increased Tick Prevalence: The July 18 31, 2011 By Michael Dryden, DVM, PhD & Susan Little, DVM, PhD AAHA gratefully acknowledges Merial, Ltd. for their sponsorship of this webcast. Increased Tick Prevalence:
More informationBloodsuckers in the woods... Lyric Bartholomay Associate Professor Department of Entomology Iowa State University
Bloodsuckers in the woods... Lyric Bartholomay Associate Professor Department of Entomology Iowa State University Characteristics Adapted for ectoparasitism: Dorsoventrally flattened Protective exoskeleton
More informationTick-Borne Infections Council
Tick-Borne Infections Council of North Carolina, Inc. 919-215-5418 The Tick-Borne Infections Council of North Carolina, Inc. (TIC-NC), a 501(c)(3) non-profit organization, was formed in 2005 to help educate
More information* * CATS. 8 weeks and Older and Weighing Over 1.5 lbs. How to Apply CAUTION FOR CATS
How to Apply OPEN Applicator Hold upright with foil side toward you and snap applicator tip. p APPLY FRONTLINE Plus Part the cat s hair above the shoulder blades, at the base of the neck. Place the applicator
More informationTICK RESISTANCE TO ACARICIDES. Dr. Obadiah N. Njagi, PhD DEPUTY DIRECTOR Date:14/11/2013 1
TICK RESISTANCE TO ACARICIDES Dr. Obadiah N. Njagi, PhD DEPUTY DIRECTOR Date:14/11/2013 1 INTRODUCTION Chemical tick control is currently the most practical method of controlling ticks in Kenya. Almost
More informationIncredible. xng237353_techdetailer4thtick9x12_rsg.indd 1
Incredible. xng237353_techdetailer4thtick9x12_rsg.indd 1 xng237353_techdetailer4thtick9x12_rsg.indd 2 For dog owners who prefer to help protect their pets from fleas and ticks with an oral product that
More informationDoug Carithers 1 William Russell Everett 2 Sheila Gross 3 Jordan Crawford 1
Comparative Efficacy of fipronil/(s)-methoprene-pyriproxyfen (FRONTLINE Gold) and Sarolaner (Simparica ) Against Induced Infestations of Ixodes scapularis on Dogs Doug Carithers 1 William Russell Everett
More informationOn-Farm Salmonella Control Measures For. Pest Control
On-Farm Salmonella Control Measures For Layers Pest Control Rodents And Other Animals All animals, including birds and reptiles, can carry Salmonella spp. Control of Salmonella spp. from mammals such as
More informationTicks and their control
Ticks and their control Jeff Hahn, Entomology There are thirteen known species of ticks in Minnesota. The majority of these species are known as hard ticks, i.e. they have a relatively hard body and possess
More informationNIAA Resolutions Bovine Committee
2016-2017 NIAA Resolutions Bovine Committee Mission: To bring the dairy cattle and beef cattle industries together for implementation and development of programs that assure the health and welfare of our
More informationThe Arachnids. Be able to recognize a representative mite from each of the following 5 families: Dermanyssidae
Laboratory 7 pg. 1 LABORATORY 7 Introduction: The Arachnids Adult arachnids are eight-legged arthropods with anterior body segments fused into a cephalothorax bearing walking legs, sensory structures and
More informationLABORATORY. The Arachnids. Introduction: Objectives: At the Bench. Laboratory 6 pg. 1
Laboratory 6 pg. 1 LABORATORY 6 Introduction: The Arachnids Adult arachnids are eight-legged arthropods with anterior body segments fused into a cephalothorax bearing walking legs, sensory structures and
More informationDr. Mike Short Division of Animal Industry
Dr. Mike Short Division of Animal Industry Cochliomyia hominivorax Only insect known to consume living tissue of warm- blooded animals Currently endemic in South America and some Caribbean Islands, including
More informationPETCARE IMMUNIZATION SUPPORT GUARANTEE
PETCARE IMMUNIZATION SUPPORT GUARANTEE 1 Zoetis will cover reasonable diagnostic and treatment costs up to $5,000 if a pet vaccinated with one of the Zoetis antigens listed below contracts the corresponding
More informationDeer Ticks...One bite can
Deer Ticks...One bite can change your life... Marion Garden Group February 7, 2017 Larry Dapsis Deer Tick Project Coordinator - Entomologist www.capecodextension.org 508-375-6642 Incidence Rate Lyme: 2014
More information5/21/2018. Speakers. Objectives Continuing Education Credits. Webinar handouts. Questions during the webinar?
Tick-borne Diseases: What NJ Public Health Professionals Need to Know Speakers Kim Cervantes, Vectorborne Disease Program Coordinator, New Jersey Department of Health Andrea Egizi, Research Scientist,
More informationScience and Art of Flea and Tick Control:
Science and Art of Flea and Tick Control: Michael W. Dryden, DVM, Ph.D. Professor of Veterinary Parasitology Department of Diagnostic Medicine/Pathobiology College of Veterinary Medicine, Kansas State
More informationREPORT TO THE BOARDS OF HEALTH Jennifer Morse, M.D., Medical Director
Ticks and Tick-borne illness REPORT TO THE BOARDS OF HEALTH Jennifer Morse, M.D., Medical Director District Health Department #10, Friday, May 19, 2017 Mid-Michigan District Health Department, Wednesday,
More informationAN APPLIED CASE STUDY of the complexity of ecological systems and process: Why has Lyme disease become an epidemic in the northeastern U.S.
AN APPLIED CASE STUDY of the complexity of ecological systems and process: Why has Lyme disease become an epidemic in the northeastern U.S. over the last few decades? What causes Lyme disease? 1 Frequency
More informationDEET and Ticks. Ultrathon, Sawyer and other Extended Duration formula may last 6 12 hours (4)
DEET and Ticks 33% extended duration cream on skin, simulated forest floor trial Repellency every 2 hours without reapplication 97% protection from lone star nymphs over 12 hours (1) 33% extended duration
More informationClinical Protocol for Ticks
STEP 1: Comprehensive Overview Clinical Protocol for Ticks Chris Adolph, DVM, MS Southpark Veterinary Hospital Broken Arrow, Oklahoma Even astute owners may not detect tick infestation until ticks have
More informationKILLS FLEAS AND TICKS WITH THE POWER OF 3
KILLS FLEAS AND TICKS WITH THE POWER OF 3 www.frontline.com THE POWER OF 3 IN ACTION. EASY-TO-USE APPLICATOR 1 EFFECTIVE Kills adult fl eas, fl ea larvae, fl ea eggs and 4 common species of ticks 2 FAST
More informationEXPLANATION OF PROPOSED RULE
EXPLANATION OF PROPOSED RULE The Texas Animal Health Commission (Commission) proposes amendments to Chapter 51 entitled "Entry Requirements." The purpose of these amendments is to make the entry requirements
More informationWildlife Services, in partnership with other Federal agencies, provides Federal leadership and expertise to resolve wildlife conflicts that threaten p
Testimony of Mr. Bill Clay Acting Associate Administrator Animal and Plant Health Inspection Service U.S. Department of Agriculture Senate Environment and Public Works Subcommittees on Oversight and on
More informationRESULTS OF 5 YEARS OF INTEGRATED TICK MANAGEMENT IN RESIDENTIAL FAIRFIELD COUNTY, CT
RESULTS OF 5 YEARS OF INTEGRATED TICK MANAGEMENT IN RESIDENTIAL FAIRFIELD COUNTY, CT Scott C. Williams Center for Vector Biology & Zoonotic Diseases The CT Agricultural Experiment Station Pioneer Press:
More informationIs Talking About Ticks Disease.
Everyone Is Talking About Ticks And Lyme Disease. Is Your Dog At Risk? What is Lyme Disease? Lyme disease is an infectious disease. In rth America, it is primarily transmitted by deer ticks, also known
More informationIn vitro feeding of all stages of Ixodes ricinus ticks
In vitro feeding of all stages of Ixodes ricinus ticks J.Bouwmans 2012 Student: Ing. I.Y.A. Wayop BSc Student number: 3260240 Research Master of Veterinary Science Duration: 6 February 2012-6 may 2012
More informationTHE ONLY FLEA AND TICK PROTECTION THAT LASTS UP TO 12 WEEKS * WITH A SINGLE CHEW
THE ONLY FLEA AND TICK PROTECTION THAT LASTS UP TO 12 WEEKS * WITH A SINGLE CHEW 1 DOSE. 12 EXTRAORDINARY WEEKS OF FLEA AND TICK PROTECTION. AN EXTRAORDINARY WAY TO PROTECT YOUR DOG 1 DOSE 4 WEEKS 8 WEEKS
More informationApproaches towards tick and tick-borne diseases control
Revista da Sociedade Brasileira de Medicina Tropical 46(3):265-269, May-Jun, 2013 http://dx.doi.org/10.1590/0037-8682-0014-2012 Review Case Report Article Approaches towards tick and tick-borne diseases
More informationLyme Disease in Dogs Borreliosis is a Bit of a Bugger!
Lyme Disease in Dogs Borreliosis is a Bit of a Bugger! I love most things about Summer. Hot weather. Barbecues. Boating on the lake. Making memories with friends. Yet with the warmer season comes those
More informationLearning objectives. Case: tick-borne disease. Case: tick-borne disease. Ticks. Tick life cycle 9/25/2017
Learning objectives Medically Significant Arthropods: Identification of Hard-Bodied Ticks ASCLS Region V October 6, 2017 1. Describe the tick life cycle and its significance 2. Compare anatomical features
More informationPersonal Protection: Topical Repellents
Personal Protection: Topical Repellents Susan Jennings Senior Public Health Advisor Office of Pesticide Programs US Environmental Protection Agency May 16, 2016 Topical Repellents and IPM Repellents are
More informationLyme Disease. Disease Transmission. Lyme disease is an infection caused by the Borrelia burgdorferi bacteria and is transmitted by ticks.
Lyme disease is an infection caused by the Borrelia burgdorferi bacteria and is transmitted by ticks. The larval and nymphal stages of the tick are no bigger than a pinhead (less than 2 mm). Adult ticks
More informationInsect vectors. Dr. Carmen E. Rexach Micro 1 Mt SAC Biology Department Internet version
Insect vectors Dr. Carmen E. Rexach Micro 1 Mt SAC Biology Department Internet version Biological vs mechanical transmission Mechanical Pathogen is picked up from a source and deposited on another location
More informationHeartwater. Prevention Practices
Heartwater Prevention Practices Route(s) of Transmission: aerosol Introduction Heartwater is caused by a bacteria that is spread through ticks and affects: Cows Sheep Goats Antelope Buffalo Signs of illness
More informationANNEX I SUMMARY OF PRODUCT CHARACTERISTICS
ANNEX I SUMMARY OF PRODUCT CHARACTERISTICS 1 1. NAME OF THE VETERINARY MEDICINAL PRODUCT NexGard 11 mg chewable tablets for dogs 2-4 kg NexGard 28 mg chewable tablets for dogs > 4-10 kg NexGard 68 mg chewable
More informationIf empty: Place in trash or offer for recycling if available. CONTAINER HANDLING. Nonrefillable container. Do not reuse or refill this container.
Distributed by: TruRx, LLC 500 E Shore Drive, Eagle, ID 8616 Distributed EPA Reg. by: No. TruRx, 88052-1-89609 LLC 500 E Shore Drive, EPA Eagle, Est. No. ID 8616 089609-FL-001 EPA Est. This No. EPA 74720-DEU-01
More informationProduct Performance Test Guidelines OPPTS Treatments to Control Pests of Humans and Pets
United States Environmental Protection Agency Prevention, Pesticides and Toxic Substances (7101) EPA 712 C 98 411 March 1998 Product Performance Test Guidelines OPPTS 810.3300 Treatments to Control Pests
More informationCanine Anaplasmosis Anaplasma phagocytophilum Anaplasma platys
Canine Anaplasmosis Anaplasma phagocytophilum Anaplasma platys It takes just hours for an infected tick to transmit Anaplasma organisms to a dog. What is canine anaplasmosis? Canine anaplasmosis is a disease
More informationBY USING DIFFERENT IN VITRO TESTS*
Indian J. Anim. Res., 46 (3) : 248-252, 2012 AGRICULTURAL RESEARCH COMMUNICATION CENTRE www.ar.arccjour ccjournals.com / indianjournals.com nals.com EVAL ALUATION OF THE COMMONLY USED ACARICIDES AGAINST
More informationUse of Cattle Movement Data and Epidemiological Modeling to Improve Bovine Tuberculosis Risk-based Surveillance
Use of Cattle Movement Data and Epidemiological Modeling to Improve Bovine Tuberculosis Risk-based Surveillance Scott Wells College of Veterinary Medicine University of Minnesota Minnesota Bovine TB, 2005-2009
More informationIf empty: Place in trash or offer for recycling if available. CONTAINER HANDLING. Nonrefillable container. Do not reuse or refill this container.
USE ONLY ON WEIGHING OVER 1.5 lbs & 8 WEEKS or OLDER KILLS FLEAS, FLEA EGGS & LARVAE and CHEWING LICE Kills all stages of ticks including those that may transmit Lyme disease FAST ACTING LONG-LASTING WATERPROOF
More informationWhat s Bugging You? Mosquitoes and ticks SAMPLE
What s Bugging You? Mosquitoes and ticks Written and illustrated by Joe Sutliff Developed by the Fairfax County Health Department 1 The Disease Carrying Insects Program (DCIP) was established in 2003 to
More informationWisconsin Bovine TB Update
Wisconsin Bovine TB Update Dr. Darlene Konkle Assistant State Veterinarian Wisconsin Department of Agriculture, Trade and Consumer Protection (DATCP) Division of Animal Health Mycobacterium species M.
More informationPowerful Flea and Tick Control Made Just For Cats Helps Consumers Protect their Pets from Harmful Pests
Powerful Flea and Tick Control Made Just For Cats Helps Consumers Protect their Pets from Harmful Pests Catego s ability to kill and control fleas and ticks, combined with easy application, gives pet owners
More informationEUROPEAN REFERENCE LABORATORY (EU-RL) FOR BOVINE TUBERCULOSIS WORK-PROGRAMME PROPOSAL Version 2 VISAVET. Universidad Complutense de Madrid
EUROPEAN COMMISSION HEALTH & CONSUMERS DIRECTORATE-GENERAL Directorate D Animal Health and Welfare Unit D1- Animal health and Standing Committees EUROPEAN REFERENCE LABORATORY (EU-RL) FOR BOVINE TUBERCULOSIS
More informationWageningen Bioveterinary Research. Biomedical and veterinary research to safeguard animal and public health
Wageningen Bioveterinary Research Biomedical and veterinary research to safeguard animal and public health Veterinary research to safeguard animal and public health Wageningen Bioveterinary Research (WBVR)
More information9/26/2018 RESULTS OF 5 YEARS OF INTEGRATED TICK MANAGEMENT IN RESIDENTIAL FAIRFIELD COUNTY, CT PUBLICATIONS PUBLICATIONS PUBLICATIONS
RESULTS OF 5 YEARS OF INTEGRATED TICK MANAGEMENT IN RESIDENTIAL FAIRFIELD COUNTY, CT Scott C. Williams Center for Vector Biology & Zoonotic Diseases The CT Agricultural Experiment Station PUBLICATIONS
More informationBiology and Control of Insects and Rodents Workshop The Biology of Urban Rodents as it Relates to Disease Potential
The Biology Of Urban Rodents As it Relates to Disease Potential NEHA Conference June 23, 2006 Add corrigan; max wts. Here. Are there a lot of rodents in many of America s Cities? Yes. Page 1 Killing some
More informationOral fertility control for grey squirrels
Oral fertility control for grey squirrels Summary The National Wildlife Management Centre (NWMC), under the terms of a contract with the UK Squirrel Accord, is researching the development and delivery
More informationMarch)2014) Principal s News. BV West Elementary Orbiter. Upcoming)Events)
May2014 BV West Elementary Orr WestElementarySchool 61N.ThirdSt. Ostrander,Ohio43061 Phone:(74066642731 Fax:(74066642221 March2014 DevinAnderson,Principal CharleneNauman,Secretary KimCarrizales,Secretary
More informationMarch 22, Thomas Kroll, Park Manager and Arboretum Director Saint John s University New Science Center 108 Collegeville, MN
March 22, 2007 Thomas Kroll, Park Manager and Arboretum Director Saint John s University New Science Center 108 Collegeville, MN 56321-3000 Dear Mr. Kroll, The Minnesota Department of Health (MDH) sampled
More informationFACULTY OF VETERINARY MEDICINE
FACULTY OF VETERINARY MEDICINE DEPARTMENT OF VETERINARY PARASITOLOGY AND ENTOMOLOGY M.Sc. AND Ph.D. DEGREE PROGRAMMES The postgraduate programmes of the Department of Veterinary Parasitology and Entomology
More information