Envigo RMS, Inc. Research Models and Services. North America Price List

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1 Envigo RMS, Inc. Research Models and Services North America Price List Effective January 1, 2015 v2

2 Inbred Mice 129P2 129P2/OlaHsd 3-4 $29.35 $ $32.80 $ $35.35 $ $37.55 $ $41.90 $44.45 Over 8 weeks, add/week $3.35 $3.35 Untimed pregnant $ Timed mated $ Female with litter $ Proven breeder $35.65 $35.65 Retired breeder $25.50 $ S2 129S2/SvHsd 3-4 $29.35 $ $32.80 $ $35.35 $ $37.55 $ $41.90 $44.45 Over 8 weeks, add/week $3.35 $3.35 Untimed pregnant $ Timed mated $ Female with litter $ Proven breeder $35.65 $35.65 Retired breeder $25.50 $25.50 A/J A/JOlaHsd 3-4 $50.95 $ $54.90 $ $58.85 $ $61.50 $ $70.15 $88.20 Over 8 weeks, add/week $6.95 $6.95 Untimed pregnant $ Timed mated $ Female with litter $ Proven breeder $93.55 $ Retired breeder $87.95 $87.95

3 Inbred Mice BALB/c BALB/cAnNHsd Approx. Weight (g) Male Female 3-4 Up to 12 Up to 12 $22.25 $ $23.75 $ $25.10 $ $27.65 $ $30.30 $32.20 Over 8 weeks, add/week $3.65 $3.50 Untimed pregnant $ Timed mated $ Female with litter $ Proven breeder $30.70 $31.45 Retired breeder $21.80 $22.65 C3H C3H/HeNHsd 3-4 $26.00 $ $27.00 $ $28.90 $ $31.40 $ $34.70 $34.80 Over 8 weeks, add/week $4.15 $4.30 Untimed pregnant $ Timed mated $ Female with litter $ Proven breeder $36.50 $41.05 Retired breeder $22.95 $26.15 C57BL/6 C57BL/6NHsd Approx. Weight (g) Male Female 3-4 Up to 12 Up to 12 $21.40 $ $23.35 $ $24.95 $ $27.35 $ $31.05 $31.70 Over 8 weeks, add/week $3.55 $3.70 Untimed pregnant $ Timed mated $ Female with litter $ Proven breeder $32.80 $36.45 Retired breeder $20.95 $22.60

4 Inbred Mice C57BL/10 C57BL/10ScNHsd 3-4 $26.50 $ $28.40 $ $30.45 $ $34.20 $ $36.65 $42.75 Over 8 weeks, add/week $4.80 $5.25 Untimed pregnant $ Timed mated $ Female with litter $ Proven breeder $44.20 $52.95 Retired breeder $30.10 $35.90 CBA/J CBA/JCrHsd 3-4 $26.90 $ $28.95 $ $31.50 $ $34.10 $ $36.70 $39.20 Over 8 weeks, add/week $3.90 $3.90 Untimed pregnant $ Timed mated $ Female with litter $ Proven breeder $38.65 $45.65 Retired breeder $29.00 $34.25 DBA/1 DBA/1OlaHsd 3-4 $39.95 $ $42.45 $ $45.15 $ $47.60 $ $50.10 $50.10 Over 8 weeks, add/week $4.80 $4.80 Untimed pregnant $ Timed mated $ Female with litter $ Proven breeder $45.15 $51.25 Retired breeder $27.70 $31.50

5 Inbred Mice DBA/2 DBA/2NHsd 3-4 $33.45 $ $36.60 $ $37.30 $ $40.30 $ $45.05 $44.60 Over 8 weeks, add/week $4.20 $4.15 Untimed pregnant $ Timed mated $ Female with litter $ Proven breeder $41.25 $47.10 Retired breeder $28.15 $28.25 FVB FVB/NHsd 3-4 $24.30 $ $26.00 $ $27.40 $ $32.20 $ $34.65 $38.75 Over 8 weeks, add/week $2.30 $2.50 Untimed pregnant $ Timed mated $ Female with litter $ Proven breeder $30.95 $36.60 Retired breeder $24.00 $28.40 SJL/J SJL/JCrHsd 3-4 $28.70 $ $30.45 $ $32.20 $ $34.55 $ $36.85 $ $38.85 $ $41.30 $ $44.05 $ $46.75 $ $49.35 $52.30 Untimed pregnant $ Female with litter $265.95

6 Outbred Mice ICR Hsd:ICR (CD-1 ) Weight (g) Up to 11 $ $ $ $ $ $ $ $8.75 Untimed pregnant $35.60 Timed mated $55.60 Female with litter $78.75 Proven breeder $37.90 Retired breeder $7.00 ND4 Swiss Webster Hsd:ND4 Weight (g) Up to 11 Grams $ $ $ $ $ $ $ $8.55 Untimed pregnant $35.20 Timed mated $56.60 Female with litter $79.40 Proven breeder $32.95 Retired breeder $6.80 NIH Swiss Hsd:NIHS Weight (g) Up to 11 Grams $ $ $ $ $ $ $ $12.55 Untimed pregnant $45.55 Timed mated $83.90 Female with litter $ Proven breeder $45.55 Retired breeder $8.40

7 Outbred Mice NSA (Non-Swiss Albino) Hsd:NSA (CF-1 ) Weight (g) Up to 11 Grams $ $ $ $ $ $ $ $8.60 Untimed pregnant $35.15 Timed mated $56.10 Female with litter $78.75 Proven breeder $34.45 Retired breeder $6.75

8 Hybrid Mice B6C3F1 B6C3F1/Hsd 3-4 $24.05 $ $25.50 $ $28.23 $ $30.90 $ $33.85 $32.65 Over 8 weeks, add/week $4.20 $4.30 Untimed pregnant $ Timed mated $ Female with litter $ Proven breeder $33.05 $32.05 Retired breeder $20.80 $20.15 B6D2F1 B6D2F1/Hsd 3-4 $22.30 $ $24.60 $ $26.00 $ $29.50 $ $31.60 $33.75 Over 8 weeks, add/week $4.30 $4.30 Untimed pregnant $ Timed mated $ Female with litter $ Proven breeder $37.15 $32.05 Retired breeder $25.30 $20.15 CB6F1 CB6F1/Hsd 3-4 $30.05 $ $32.20 $ $34.15 $ $37.40 $ $38.80 $41.50 Over 8 weeks, add/week $4.60 $4.60 Untimed pregnant $ Timed mated $ Female with litter $ Proven breeder $36.20 $36.20 Retired breeder $30.05 $30.05

9 Hybrid Mice CD2F1 CD2F1/Hsd 3-4 $22.85 $ $25.15 $ $26.90 $ $29.85 $ $31.50 $30.95 Over 8 weeks, add/week $4.30 $4.20 Untimed pregnant $ Timed mated $ Female with litter $ Proven breeder $31.55 $26.40 Retired breeder $23.25

10 Mutant Mice (Spontaneous) - Nudes Athymic Nude Mouse Hsd:Athymic Nude-Foxn1 nu Animals Animals 250+ Animals Male Female Male Female 3-4 $68.75 $80.95 $51.05 $59.40 $43.25 $ $69.25 $81.85 $52.55 $61.55 $44.75 $ $70.10 $81.90 $54.05 $63.20 $46.15 $ $76.75 $90.90 $59.50 $70.05 $50.10 $ $81.00 $91.40 $65.40 $72.80 $56.20 $62.40 Male Female Over 8 weeks, add/week $6.25 $6.25 Proven breeder $ Retired breeder $57.35 Athymic Nude Mouse - heterozygous Hsd:Athymic Nude-Foxn1 nu /Foxn1 + Age (weeks) 3-4 $ $ $ $ $38.45 Over 8 weeks, add/week $6.65 Untimed pregnant upon request Timed mated upon request Female with litter upon request Proven breeder $ Retired breeder $24.95 Beige Nude XID Hsd:NIHS-Lyst bg Foxn1 nu Btk xid Age (weeks) nu/nu nu /+ 3-4 $90.95 $ $93.10 $ $93.45 $ $94.65 $ $99.75 $53.80 Over 8 weeks, add/week $7.65 $8.20 Untimed pregnant Timed mated Female with litter Proven breeder upon request upon request upon request upon request Retired breeder $ $81.30

11 Mutant Mice (Spontaneous) - Nudes SCID C.B-17/IcrHsd-Prkdc scid Age (weeks) 4-5 $ $ $ $98.65 Over 8 weeks, add/week $8.30 SCID /Beige C.B-17/IcrHsd-Prkdc scid Lyst bg Age (weeks) 4-5 $ $ $ $ Over 8 weeks, add/week $8.65 NOD.SCID NOD.CB17-Prkdc scid /NCrHsd 4-5 $ $ $ $ $ $ $ $ Over 8 weeks, add/week $13.35 $12.30

12 Mutant Mice (Spontaneous) - Diabetic/Obese Diabetic db/db BKS.Cg -+Lepr db /+Lepr db /OlaHsd Age (weeks) db/db lean 3-4 $ $ $ $ $ $ $ $ $ $98.80 Over 8 weeks, add/week $4.90 $3.35 Retired breeder $ $75.20 Obese ob/ob B6.V-Lep ob /OlaHsd Age (weeks) ob/ob lean 4-5 $ $ $ $ $ $ $ $92.45 Over 8 weeks, add/week $4.90 $3.30 Retired breeder $ $73.60

13 Mutant Mice (Spontaneous) - Other Albino C57BL/6 C57BL/6BrdCrHsd-Tyr c 3-4 $27.30 $ $30.10 $ $32.25 $ $37.75 $ $42.80 $43.30 Over 8 weeks, add per week $5.05 $5.05 Untimed pregnant $ Timed mated $ Female with litter $ Proven breeder $45.10 $45.10 Retired breeder $28.80 $27.95

14 Inbred Rats ACI ACI/SegHsd Approx. Weight (g) Price per Animal 3-4 Up to 50 Up to 50 $ $ $ $ $ $ $ $ Untimed pregnant $ Timed mated $ Female with litter $ Proven breeder $ Retired breeder $67.25 Brown Norway BN/RijHsd Approx. Age (days) Weight (g) Male Female Male Female Less than 49g $51.80 $ $55.80 $ $59.55 $ $63.80 $ $71.35 $ $81.60 $ $87.60 $ $91.40 $ $97.15 $ $ upon request Untimed pregnant $ Timed mated $ Female with litter $ Proven breeder $ $ Retired breeder $48.00 $55.95

15 Inbred Rats DA DA/OlaHsd Age (weeks) 3-4 $ $ $ $ $ $ $ $ $ $ $ $ $ Dahl Salt Sensitive (Rapp) SS/JrHsd SR/JrHsd Age (weeks) 3-4 $ $ $ $ $ $ $ $ $ $ $ $ Untimed pregnant $ Timed mated $ Female with litter $ Proven breeder $ Retired breeder $92.45

16 Inbred Rats Fischer 344 F344/NHsd Approx. Age (days) Weight (g) Male Female Male Female Less than 49g $30.10 $ $30.50 $ $35.30 $ $42.20 $ $46.30 $ $52.10 $ $55.50 $ $64.90 $ $ $ $79.40 Untimed pregnant $ Timed mated $ Female with litter $ Proven breeder $66.55 $ Retired breeder $42.20 Lewis LEW/SsNHsd Approx. Age (days) Weight (g) Male Female Male Female Less than 49g $30.10 $ $34.20 $ $37.70 $ $40.45 $ $46.55 $ $49.90 $ $58.35 $ $63.00 $ $ $ $77.95 Untimed pregnant $ Timed mated $ Female with litter $ Proven breeder $59.85 $ Retired breeder $40.05 $43.00

17 Inbred Rats Spontaneously Hypertensive SHR/NHsd Age (weeks) 3-4 $ $ $ $ $ $ $ $ $ $ $ $ Untimed pregnant $ Timed mated $ Female with litter $ Proven breeder $ Retired breeder $90.35 Wistar Furth WF/NHsd Approx. Weight (g) Price per Animal 3-4 Up to 60 Up to 60 $ $ $ $ $ $ $ $ upon request Untimed pregnant $ Timed mated $ Female with litter $ Proven breeder $ Retired breeder $87.50

18 Inbred Rats Wistar Kyoto WKY/NHsd Age (weeks) 3-4 $ $ $ $ $ $ $ $ $ $ $ $ Untimed pregnant $ Timed mated $ Female with litter $ Proven breeder $ Retired breeder $91.80

19 Outbred Rats Holtzman HsdHot:Holtzman SD Approx. Age (days) Weight (g) Male Female Male Female $19.75 $ $24.00 $ $26.05 $ $28.55 $ $31.65 $ $33.90 $ $36.75 $ $39.10 $ $41.70 $ $45.10 $ $49.85 $ $ $ $ $ upon request Untimed pregnant $ Timed mated $ Female with litter $ Proven breeder $54.40 $80.90 Retired breeder $35.80 $37.60 Long Evans (Blue Spruce) HsdBlu:LE Approx. Age (days) Weight (g) Male Female Male Female $18.50 $ $21.60 $ $26.15 $ $29.30 $ $31.95 $ $34.67 $ $37.75 $ $40.95 $ $46.35 $ $50.00 $ $53.05 $ $ $ $ upon request Untimed pregnant $ Timed mated $ Female with litter $ Proven breeder $62.02 $69.30 Retired breeder $41.10 $39.35

20 Outbred Rats Sprague Dawley Hsd:Sprague Dawley SD Approx. Age (days) Weight (g) Male Female Male Female $14.20 $ $17.95 $ $22.05 $ $25.00 $ $29.15 $ $30.45 $ $35.60 $ $38.30 $ $41.25 $ $44.60 $ $47.10 $ $ $ $ $ upon request Untimed pregnant $ Timed mated $ Female with litter $ Proven breeder $65.98 $67.20 Retired breeder $41.20 $38.65 Wistar Hsd:WI Approx. Age (days) Weight (g) Male Female Male Female $18.15 $ $22.00 $ $25.65 $ $29.20 $ $31.00 $ $35.90 $ $38.40 $ $41.55 $ $45.05 $ $47.10 $ $ $ $ $ upon request Untimed pregnant $ Timed mated $ Female with litter $ Proven breeder $58.65 $66.10 Retired breeder $36.95 $37.80

21 Outbred Rats Wistar Han RccHan :WIST Approx. Age (days) Weight (g) Male Female Male Female $16.35 $ $21.20 $ $25.00 $ $28.50 $ $31.50 $ $33.10 $ $37.75 $ $41.05 $ $44.45 $ $47.95 upon request $51.80 upon request $ $ $ $ upon request Untimed pregnant $ Timed mated $ Female with litter $ Proven breeder $64.35 $72.50 Retired breeder $41.50 $39.45

22 Mutant Rats (Spontaneous) Athymic Nude Rat Hsd:RH-Foxn1 rnu Age (weeks) rnu/rnu rnu/+ 3-4 $ $ $ $ $ $ $ $ $ $ $ $ $ $ Over 10 weeks, add/week $37.55 $35.05 Zucker HsdHlr:ZUCKER-Lepr fa Age (weeks) fa/fa lean 3-4 $ $ $ $ $ $ $ $ $ $ $ $ $ $90.60 Over 10 weeks, add/week $21.95 $11.70

23 Transgenic Rats HIV-1 Hsd:HIV-1(F344) Age (weeks) 3-4 $ $ $ $ $ $ $ Over 10 weeks, add per week $71.80

24 Hamsters and Cotton Rats Golden Syrian Hamster HsdHan :AURA Approx. Weight (g) Male Female $29.85 $ $32.75 $ $39.65 $ $45.90 $ $49.45 $ $52.00 $ $61.65 $ $71.90 $71.90 Pregnant Female $ Female with litter $ Proven breeder $61.75 $65.90 Cotton Rat Hsd:Cotton Rat Age (weeks) 3-4 $ $ $ $ $ $ $ Over 10 weeks, add per week $13.40

25 Additional Charges The following charges will be added when applicable: 2-gram weight range (mice only) add 10% 5-gram weight range (rats only) add 15% 10-gram weight range (rats only) add 10% Littermates add 10% Extra specifications for time mated or retired breeder rodents priced on request Shipping container with gel transit packets $20.65 Special double-screened heavy-wire shipping container with gel $27.00 MicroShipper with gel $52.80 Tattoo (rodents) $11.00 Ear Tag (rodents) $5.75 Import or export charges $ Fish and Wildlife Declaration Fee $ Veterinary Certificate $175.00

26 Surgical Services up to Rat Catheterizations > 5 animals 5 animals Vascular Catherizations (per animal) (per animal) Carotid Artery $90.30 $91.20 Femoral Artery $ $ Femoral Vein $89.00 $ Jugular Vein $73.95 $ Portal Vein $ $ Intracardioventricular $99.40 $ Non-Vascular Catheterizations Bile Duct - Free End $ $ Bile Duct - Closed Loop $ $ Intestinal-Duodenal $ $ Intestinal-Jejunal $ $ Gastric $ $ Intra-Colonic $ $ Multiple Procedures - Single Animal Double Vascular Catheterizations: JVC/CAC $ $ JVC/JVC $ $ FAC/FVC $ $ JVC/FVC $ $ JVC/FAC $ $ Cannulation Options Miscellaneous Each Additional Catheter Tubing (per ft) $4.95 Blunt Needles $3.15 Huber Needles $6.00 Rat Jacket w/pouch $36.70 Stainless Steel Plugs $1.80 Catheter Couplers $7.20 Hep/Gly Soln, sterile, 500 IU/mL, 10 ml bottle $28.15 Heparin-coated JVC $82.80 Culex Catheters BDCFE $46.90 CAC $26.55 FVC, short $26.55 FAC $26.55 Gastric/Duodenal/Peritoneal $28.15 JVC, short $26.55 BDCCL $ PVC $26.55 Culex Catheter SS Plug, 19g $1.80 Culex BDCCL U-Tube Connector $31.20

27 Surgical Services Cannulation Options, continued Rat Harnesses Harness, single port $48.45 Harness, dual port $71.90 Harness, quad port $92.15 Harness, dual port w/connector $ Harness, quad port w/connector $ Connector, dual/quad harness $40.60 Quik Connect Harn, single port $46.90 Harness, custom, dual port $60.15 Catheter Buttons Button stalk, single infusion $16.45 Button stalk, double infusion $16.45 Vascular Access Button, external $52.95 Catheter Ports Vascular Access Port, JVC $60.10 Vascular Access Port, FVC $ or more 5 or fewer Soft Tissue Surgical Procedures animals animals Reproductive: (per animal) (per animal) Castration - rat $20.40 $37.15 Castration - mouse $22.15 $39.40 Ovariectomy - rat $21.75 $42.05 Ovariectomy - mouse $23.35 $41.85 Vasectomy - rat $29.75 $51.35 Vasectomy - mouse $29.75 $53.10 Endocrine: Hypo-Intra-aural - rat upon request upon request Additional: Nephrectomy-Unilateral - rat $36.05 $63.45 Nephrectomy-Unilateral - mouse $38.40 $67.10 Immunodeficient Models Reproductive: Castration - rat $36.75 $52.00 Castration - mouse $38.05 $50.50 Ovariectomy - rat $37.75 $49.85 Ovariectomy - mouse $38.05 $46.80 Vasectomy - rat $44.10 $59.25 Vasectomy - mouse $45.40 $57.40 Additional Charges Each Surgical development fee for surgeries not listed (with exceptions - please contact your Envigo representative) $300.00

INVIVOS 2018 PRICE LIST

INVIVOS 2018 PRICE LIST INVIVOS 2018 LIST OUTBRED MICE MPF IcrTac:ICR 3-4 M 28.70 F 28.70 Common Name: ICR 5-6 M 33.35 F 33.35 7-8 M 36.20 F 36.20 9-10 M 40.00 F 40.00 Female with litter 128.35 Untimed Pregnant* 73.50 Time-mated