PETCARE IMMUNIZATION SUPPORT GUARANTEE

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PETCARE IMMUNIZATION SUPPORT GUARANTEE 1

Zoetis will cover reasonable diagnostic and treatment costs up to $5,000 if a pet vaccinated with one of the Zoetis antigens listed below contracts the corresponding disease after January 1, 2018. Conditions: The pet must be vaccinated by a licensed veterinarian with an established client-patient relationship.* A veterinarian (or appropriate veterinary health care team member) must be the primary point of contact for the guarantee to be valid. Zoetis will direct all claims from pet owners, breeders, etc., to the vaccinating veterinarian. For the core vaccine Zoetis Petcare Immunization Support Guarantee (4 years) to be valid, the pet must have received an age-appropriate initial vaccination series as per the vaccine label. A Zoetis vaccine must be the most recent vaccine used in the series. Per AAHA/AAFP Vaccination Guidelines, a 1-year booster is recommended after the initial puppy/kitten series. When a series is required, the two vaccines should ideally be given according to the label instructions, but no sooner than 2 and no greater than 6 weeks apart. For the non-core vaccine Zoetis Petcare Immunization Support Guarantee (1 year) to be valid, the pet must have completed an age-appropriate vaccination series as per the vaccine label. A Zoetis vaccine must be the most recent vaccine used in the series. Any animal vaccinated in accordance with the AAHA/AAFP Vaccination Guidelines, with the appropriate Zoetis vaccines and in an established veterinarian/patient relationship*, is fully covered under the Zoetis Petcare Immunization Support Guarantee. For the Feline Leukemia support guarantee (2 years) to be valid, the medical record must document a negative FeLV test at the time of immunization. All payments made under the Zoetis Petcare Immunization Support Program may require a signed consent form from the veterinarian and/or pet owner. Defensor and Felocell FIP vaccines are not supported as part of the Zoetis Petcare Immunization Support Guarantee. *As defined in the Code of Federal Regulations (21 C.F.R. 530.3 (2018)). 2

Claims: At the time of a claim, veterinarians must collaborate with Zoetis Veterinary Medical Information and Product Support (VMIPS) in designing an appropriate diagnostic and treatment regimen. A diagnosis must be made using criteria predetermined by VMIPS. To contact VMIPS, call 1-888-963-8471. At the time of a claim, information including the vaccine brand, serial number, and date of vaccination must be provided. At the time of a claim, vaccine purchase history will be verified by VMIPS. Claims involving vaccines purchased from unauthorized sources will not be supported under the Zoetis Petcare Immunization Support Guarantee. Claims involving animal species other than those on the product label are not covered. Claims involving puppies and kittens less than 15 weeks of age, or involving onset of disease within 3 weeks (2 weeks for Canine Influenza Virus) of completing the initial immunization series, are not covered. For Bordetella bronchiseptica and intranasal respiratory vaccines, coverage begins 1 week after completion of the vaccine series or mucosal vaccine (animals exposed prior to onset of expected immunity may not be covered). Bordetella bronchiseptica Vaccines: Zoetis is proud to support dogs who are suspected to have a Bordetella bronchiseptica infection for diagnostic and treatment (if they are in fact diagnosed) costs up to $7,500 if they have received a prime boost protocol. This protocol entails the use of a Zoetis B. bronchiseptica intranasal vaccine as the initial or priming dose. In 2 6 weeks, the dog will receive a booster dose of Bronchicine CAe. Thereafter, the dog will receive an annual injection of Bronchicine CAe. 3

Lepto Loyalty Guarantee: Zoetis will provide reimbursement for reasonable and customary costs associated with the diagnosis and treatment of acute leptospirosis in dogs meeting the criteria for the Zoetis Petcare Lepto Loyalty Guarantee. The 2010 ACVIM Small Animal Consensus Statement on Leptospirosis will be used to help define reasonable and customary; Dialysis, oxygen therapy, plasma transfusions and mechanical ventilation are all described in the guidelines as reasonable therapeutic options. Experimental or unconventional therapies (e.g., organ transplant) will not be covered. Acute treatment period will include hospitalization and up to 12 weeks of reasonable outpatient monitoring afterwards. To qualify for these additional benefits from the Zoetis Petcare Immunization Support Guarantee, the client must show that: The dog s 3 most recent Lepto vaccines must be a Vanguard L4 containing SKU. The Vanguard L4 SKU can be the initial series (with 2 doses given 2 6 weeks apart) followed by an annual booster. OR 3 annual vaccinations with Vanguard L4 containing SKU after an appropriate initial series. A grace period of up to 2 weeks will be allowed after the annual vaccine due date. Zoetis Petcare Immunization Support Guarantee qualifications must be met according to VMIPS diagnostic algorithm. Per existing Zoetis Petcare Immunization Support Guarantee rules, initial confirmatory diagnostics are to be reimbursed at laboratory cost. In the event that a case does not meet all the criteria for the Lepto Loyalty Guarantee, eligibility for routine Zoetis Petcare Immunization Support Guarantee coverage will be considered. 4

LYME AND TICK PROTECTION Lyme Vaccine: Zoetis will cover reasonable diagnostic and treatment costs up to $5,000 if a dog vaccinated with one of the Zoetis antigens listed below contracts the corresponding disease after January 1, 2017. To qualify for benefits from the Zoetis Immunization Support Guarantee, the client must show that: (1) their dog is appropriately vaccinated for Lyme disease; (2) the most recent Lyme vaccine was given in the preceding 15 months if VANGUARD crlyme was administered or in the preceding 12 months if LYMEVAX was administered; and (3) the most recent Lyme vaccine was a Zoetis Lyme vaccine (VANGUARD crlyme or LYMEVAX ). Lyme Vaccines and Tick Protection*: If the dog is diagnosed and displays clinical signs consistent with Lyme disease, Zoetis will reimburse diagnostic and treatment costs up to $7,500 if (1) the patient was vaccinated appropriately; (2) the last dose of Lyme vaccine administered was a Zoetis vaccine; AND (3) the patient has received continuous protection with Simparica (sarolaner) Chewables used according to label directions. Simparica Chewables kill adult fleas, and are indicated for the treatment and prevention of flea infestations (Ctenocephalides felis), and the treatment and control of tick infestations [Amblyomma americanum (lone star tick), Amblyomma maculatum (Gulf Coast tick), Dermacentor variabilis (American dog tick), Ixodes scapularis (black-legged tick), and Rhipicephalus sanguineus (brown dog tick)] for one month in dogs 6 months of age or older and weighing 2.8 pounds or greater. Simparica Chewables are not a vaccine. In a study, Simparica Chewables blocked the transmission of Lyme from Ixodes scapularis (Black-legged deer tick) to dogs 1. It demonstrated 98.8% efficacy against existing infestations just 12 hours after treatment 2 Lyme is typically transmitted within 24 to 48 hours. Simparica Chewables maintained a rapid speed of kill throughout the month. * Please review the Simparica Satisfaction Guarantee program requirements for detailed information on qualification and coverage. https://www.simparica.com/satisfaction-guarantee.aspx 1. Honsberger NA, et al. Efficacy of sarolaner in the prevention of Borrelia burgdorferi and Anaplasma phagocytophilum transmission from infected Ixodes scapularis to dogs. Vet Parasitol. 2016;222:67-72. 2. Six RH, et al. Evaluation of the speed of kill of sarolaner (Simparica ) against induced infestations of three species of ticks (Amblyomma maculatum, Ixodes scapularis, Ixodes ricinus) on dogs. Veterinary Parasitology 2016 May 30(222):37-42. 5

1 YEAR 15 ** MONTHS 2 YEARS 3+1 YEARS Bordetella bronchiseptica Borrelia burgdorferi (LYMEVAX) Canine Adenovirus-2 (Intranasal) Canine Coronavirus Canine Parainfluenza Virus (Intranasal) Chlamydophila felis (Chlamydia psittaci) Canine Influenza Virus Lepto Loyalty Guarantee*** Borrelia burgdorferi (Vanguard crlyme) Leptospira icterohaemorrhagiae L. canicola L. grippotyphosa L. pomona Feline Leukemia Virus Canine Adenovirus-1&2 (Injectable) Canine Distemper Virus Canine Parainfluenza Virus (Injectable) Canine Parvovirus Feline Parvovirus (Feline Panleukopenia) Feline Herpesvirus-1 Feline Calicivirus *Please review program requirements for detailed information on qualification and coverage. ** 15 month coverage applies after an appropriate initial series and a timely 1 year booster for Vanguard L4 and immediately after an appropriate initial series for Vanguard crlyme. *** Lepto Loyalty: Dogs receiving their vaccine booster between 12.5 15 months after their last dose of Leptospira vaccine will have eligibility considered for coverage with the traditional Zoetis Petcare Immunization Support Guarantee. Extended coverage begins after an appropriate initial series and a timely 1 year booster. All trademarks are the property of Zoetis Services LLC or a related company or a licensor unless otherwise noted. 2018 Zoetis Services LLC. All rights reserved. ZPC-00005 6