Table Of Content. Outputs... 8

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Table Of Content Establishment of Quality Assurances for Detection of Highly Pathogenic Bacteria of Potential Bioterrorism Risk... 2 Summary... 3 Coordinator, Leader contact and partners... 4 Swedish Institute for Infectious Disease Control - SMI... 4 NATIONAL AND KAPODISTRIAN UNIVERSITY OF ATHENS - NKUA... 4 Istituto Zooprofilattico Sperimentale della Puglia e della Basilicata - IZSPB... 4 UK Health Protection Agency - HPA... 4 National Institute for Public Health and the Environment - RIVM... 4 National Center for Epidemiology - NCEBACT... 4 Austrian Agency for Health and Food Safety - AGES... 4 National Institute for Health and Welfare - THL... 4 National Public Health Surveillance Laboratory - NPHSL... 4 National Center of Infectious and Parasitic Diseases - NCIPD... 4 BASQUE FOUNDATION FOR HEALTH INNOVATION AND RESEARCH - BIOEF... 4 Friedrich Loeffler Institute, Federal Research Institute for Animal Health - FLI... 4 Veterinary & Agrochemical Research Centre - VAR... 4 Istituto Superiore di Sanità - ISS... 4 Norwegian Institute of Public Health - NIPH... 4 National Institute of Hygiene - PZH... 4 Outputs... 8 Final report - Final report... 8 Interim report 1 - Interim report 1... 8 Oxford Presentation... 8 Presentation... 8 Website... 8 Page 1/9

Establishment of Quality Assurances for Detection of Highly Pathogenic Bacteria of Potential Bioterrorism Risk JA2015 - GPSD [705038] START DATE: 01/05/2008 END DATE: 01/08/2011 DURATION: 39 month(s) CURRENT STATUS: Finalised PROGRAMME TITLE: First Programme of Community action in the field of public health (2003-2008) PROGRAMME PRIORITY: - CALL: Responding To Health Threats Rapidly And In A Co-Ordinated Manner (Ht 2007) TOPIC: Health security and strategies relevant to communicable diseases control EC CONTRIBUTION: 1199848.51 EUR KEYWORDS: Bacteria, Diagnostic, Emergent pathogens, Health Workforce, Safety evaluation and monitoring PORTFOLIO: Communicable diseases, Preparedness and response, Risk assessment Page 2/9

SUMMARY General objectives This project was initiated in response to results of a tender by DG SANCO on an External Quality Assurance Exercise (EQAE) in 2006 revealing the need for further improvement of the diagnostic reliability of bacteria of potential bioterrorism risk. The objective is to provide the infrastructure, design, organize, and manage practical EQAEs for bacteria of potential bioterrorist risk causing anthrax, tularemia, plague, glanders, melioidosis, brucellosis, and Q- fever Strategic relevance and contribution to the public health programme The proposal contributes to Public Health programmes to minimise the health threats to its citizens by potential bioterrorist threats. The project will directly support the early warning and rapid response capacity to ensure an effective reaction to a bioterrorist attack. It fits into the Work Plan 2007 on activities countering the threat of deliberate release of biological agents. Methods and means The project will established a supportive European high threat pathogen laboratory network capable of identifying and characterising potential bioterrorist agents. 23 laboratories from 20 European countries will work together. The samples from a common repository of reference materials will be authenticated by all available microbiological, molecular and immunological approaches. Two rounds of EQAEs using samples of different complexity will be applied to estimate the current laboratories capabilities. The efficacy of improvements and training of personnel at network partners will be validated by a third round of EQAE. Expected outcomes period The project will substantially facilitate the preparedness of individual appointed laboratories in EU Member States to respond to any potential bioterrorist threat or event. A repository of relevant reference samples will be established. The network between European laboratories will highly facilitate the infrastructure to create capabilities, critical mass and skills necessary for the detection of high threat bacterial pathogens. Page 3/9

COORDINATOR, LEADER CONTACT AND PARTNERS COORDINATOR () Nordufer 20 13353 Berlin Germany Project leader contact Name: Grunow Roland Email: grunowr@rki.de Phone: +4903018752100 PARTNERS Swedish Institute for Infectious Disease Control - SMI Street: Nobels väg 18 City: 171 82 Solna Country: Sweden NATIONAL AND KAPODISTRIAN UNIVERSITY OF ATHENS - NKUA Street: MIKRAS ASIAS 75 City: ATHENS Country: Greece Istituto Zooprofilattico Sperimentale della Puglia e della Basilicata - IZSPB Street: Via Manfredonia 20 City: 71100 Foggia Country: Italy Page 4/9

UK Health Protection Agency - HPA Street: Centre for Emergency, Preparedness & Response Porton Down City: SP4 0JG Porton Down-Salisbury Country: United Kingdom National Institute for Public Health and the Environment - RIVM Street: A. van Leeuwenhoeklaan 9 City: 3721 MA Bilthoven Country: Netherlands National Center for Epidemiology - NCEBACT Street: Gyáli út 2-6 City: 1097 Budapest Country: Hungary Austrian Agency for Health and Food Safety - AGES Street: Währingerstrasse 25a City: 1226 Vienna Country: Austria National Institute for Health and Welfare - THL Street: Mannerheimintie 166 City: 00300 Helsinki Country: Finland National Public Health Surveillance Laboratory - NPHSL Street: Zolyno 36 City: 10210 Vilnius Country: Lithuania National Center of Infectious and Parasitic Diseases - NCIPD Page 5/9

Street: Yanko Sakazov 26 City: 1504 Sofia Country: Bulgaria BASQUE FOUNDATION FOR HEALTH INNOVATION AND RESEARCH - BIOEF Street: PLAZA DE ASUA 1 City: 48150 SONDIKA Country: Spain Friedrich Loeffler Institute, Federal Research Institute for Animal Health - FLI Street: Naumburger Strasse 96a City: Jena Country: Germany Veterinary & Agrochemical Research Centre - VAR Street: Groeselenberg City: 1180 Brussels 99 Country: Belgium Istituto Superiore di Sanità - ISS Street: Viale Regina Elena 299 City: 00161 Rome Country: Italy Norwegian Institute of Public Health - NIPH Street: Geitmyrsveien 75 City: 0403 Oslo Country: Norway National Institute of Hygiene - PZH Page 6/9

Street: Chocimska 24 City: 791 Warszawa Country: Poland Page 7/9

OUTPUTS Final report - Final report Interim report 1 - Interim report 1 Oxford Presentation http://azorina.cc.cec.eu.int:8082/publications/2007204/2007204_berm12_20 09_grunow_print.pdf Presentation http://azorina.cc.cec.eu.int:8082/publications/2007204/berm12_2009_gruno w_print.pdf Website Page 8/9

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