Antibiotic resistance: the rise of the superbugs
|
|
- Ruth Hubbard
- 6 years ago
- Views:
Transcription
1 Antibiotic resistance: the rise of the superbugs Allen Cheng Associate Professor of Infectious Diseases Epidemiology, Alfred Health; Monash University About me Specialist in infectious diseases Head, Infection Prevention and Healthcare Epidemiology Unit, Alfred Health Acting Director, Department of Infectious Diseases, Alfred Health Associate Professor of Infectious Diseases Epidemiology, Monash University Financial support: NHMRC, Alfred Health No funding from pharmaceutical companies 1
2 The Pre antibiotic era: Albert Alexander, 1941 Oxford policeman Scratched face with rose thorn Developed infection of face Infection spread to eyes, scalp over months Persisted despite surgery Howard Florey Australian pharmacologist Professor of Pathology at Oxford Developed methods to mass produce penicillin (Nobel Prize, 1945) Initially administered penicillin to rats Heard about Constable Alexander s case from wife 2
3 First use of penicillin Limited supplies of penicillin Given several doses Immediate improvement within 24 hours Re purified from urine Clinical response until day 5 The post antibiotic era: Alfred Hospital, 2012 Male, 30s Car accident in Thailand, multiple injuries, unconscious Admitted to intensive care in a Bangkok hospital Developed multiple infections wounds, pneumonia Transferred to The Alfred for further treatment Bloodstream infection resistant to all available antibiotics Treated with combination of 4 antibiotics died with active infection 3
4 Antibiotic resistance Use it and you will lose it evolution in action Superbugs : probably not a good term Colonisation vs infection Resistance danger Degrees of resistance Resistance associated with Patient morbidity and mortality Longer length of hospital stay Increased costs of treatment: Overall AR cost $50b in US; $25,000 per patient in 2009 RSA: TB $200; MDR: $6000 $10,000; XDR: $26,000 Perfect storm Increasing rates of resistance Decreasing development of new antibiotics New systemic antibacterial agents approved by the US FDA by 5 year period
5 Some examples MRSA VRE MDR gram negative bacteria Typhoid Malaria XDR Tuberculosis Gonorrhoea Areas impacted Hospital waiting lists and costs All surgical procedures Cardiac surgery Joint replacements Obstetrics Specialist services Intensive care Transplantation Cancer chemotherapy Patients with impaired immunity Travel related infections 5
6 Drivers of resistance Importation from overseas Antibiotic use humans, animals Cross transmission CDC Threat Report 2013 What can patients do? Prevent infection Don t use antibiotics for viral infections Take full course of antibiotics Stay away from hospitals! 6
7 What can we do in hospitals? Antibiotic stewardship quality use of antibiotics Reduce cross transmission cleaning, hand hygiene, good infrastructure Prevent infection Antibiotic use Not Colonized Colonized Infection Cross-transmission 7
8 Compliance with hand hygiene has increased from 43% in 2008 to 79% in 2014 The number of central line bloodstream infections in intensive care has decreased from 41 in 2008 to 2 in 2013 The number of Staph aureus bacteraemias has fallen from 198 in 2002 to 78 in 2013 The proportion of Staph aureus bacteraemias due to antibiotic resistant MRSA has fallen from 55% in 2002 to 22% in 2013 The proportion of Staph aureus bacteraemias acquired during hospitalisation has decreased from 46% in 2010 to 28% in 2013 The proportion of staff vaccinated against influenza has improved from <40% in 2004 to 78% in June, 2014 Antimicrobial stewardship DDD/1000OBD cephalosporins in Non-ICU month Observed Pre - intervention trend Post-intervention trend DDD/1000OBD glycopeptides in Non-ICU month Observed Pre - intervention trend Post-intervention trend Cairns MJA
9 What can we do in Australia? Co ordinated public policy humans/animals, community/hospitals Invest in infection prevention and research Track resistance rates Antibiotic stewardship and prevention of cross transmission as a standard Ensure access to new antibiotics A successful example Fluoroquinolone antibiotics particularly useful Not licensed in food producing animals Reserve antibiotic in treatment guidelines Restricted subsidy by PBS Proportion of E coli isolates resistant to quinolones.5.4 Malta Spain.3 Bulgaria Portugal Czech Republic Hungary Ireland Germany Greece Poland Austria.2 Luxembourg United Kingdom Slovenia France Belgium Latvia Lithuania Netherlands Denmark.1 Sweden Finland Norway Estonia Iceland Australia Usage (DDD/1000 population days) Italy Cyprus Cheng Emerg Infect Dis
10 National policy 1999 JETACAR report (Joint Expert Technical Advisory Committee on Antibiotic Resistance) Taskforce disbanded 2002 EAGAR (Expert Advisory Group of Antimicrobial Resistance) established by NHMRC AMRSC (Antimicrobial Resistance Subcommittee) established by Commonwealth CHO 2013 ACSQHC commissioned scoping studies 2014 Conclusions Antibiotic resistance due to antibiotic use Perfect storm of increasing resistance and declining antibiotic development Need to reduce unnecessary antibiotic use and cross transmission of resistant organisms Need for surveillance to inform co ordinated policy Interventions to reduce resistance need resources 10
Summary of the latest data on antibiotic consumption in the European Union
Summary of the latest data on antibiotic consumption in the European Union November 2012 Highlights on antibiotic consumption Antibiotic use is one of the main factors responsible for the development and
More informationSummary of the latest data on antibiotic consumption in the European Union
Summary of the latest data on antibiotic consumption in the European Union ESAC-Net surveillance data November 2016 Provision of reliable and comparable national antimicrobial consumption data is a prerequisite
More informationWhat is the problem? Latest data on antibiotic resistance
European Antibiotic Awareness Day 2009 What is the problem? Latest data on antibiotic resistance Zsuzsanna Jakab, ECDC Director Launch Seminar for EAAD Stockholm, 18 November 2009 Fluoroquinolone-resistant
More informationThe challenge of growing resistance
EXECUTIVE SUMMARY Around 2.4 million people could die in Europe, North America and Australia between 2015-2050 due to superbug infections unless more is done to stem antibiotic resistance. However, three
More informationProf. Otto Cars. We are overconsuming a global resource. It is a collective responsibility by governments, supranational organisatons
What are the consequences of rising antibiotic resistance for Sweden? Prof. Otto Cars Chairman The Swedish Strategic programme against antibiotic resistance (Strama) We are overconsuming a global resource
More informationAntimicrobial resistance (EARS-Net)
SURVEILLANCE REPORT Annual Epidemiological Report for 2014 Antimicrobial resistance (EARS-Net) Key facts Over the last four years (2011 to 2014), the percentages of Klebsiella pneumoniae resistant to fluoroquinolones,
More informationHealth Service Executive Parkgate St. Business Centre, Dublin 8 Tel:
Health Service Executive Parkgate St. Business Centre, Dublin 8 Tel: 01 635 2500 www.hse.ie Health Service Executive Oak House, Millennium Park, Naas, Co. Kildare Tel: 045 880 400 www.hse.ie The prevention
More informationA web-based interactive tool to explore antibiotic resistance and consumption via maps and charts
http://resistancemap.cddep.org A web-based interactive tool to explore antibiotic resistance and consumption via maps and charts CDDEP first developed ResistanceMap in 21. The new ResistanceMap now includes
More informationMRSA in the United Kingdom status quo and future developments
MRSA in the United Kingdom status quo and future developments Dietrich Mack Chair of Medical Microbiology and Infectious Diseases The School of Medicine - University of Wales Swansea P R I F Y S G O L
More informationEuropean Medicines Agency role and experience on antimicrobial resistance
European Medicines Agency role and experience on antimicrobial resistance Regional Training Workshop on Antimicrobial Resistance (AMR) Responding to the global challenge of AMR threats: toward a one health
More informationConsumption of antibiotics in hospitals. Antimicrobial stewardship.
Consumption of antibiotics in hospitals. Antimicrobial stewardship. Inge C. Gyssens MD PhD Radboud university medical center, Nijmegen, The Netherlands Hasselt University, Belgium 1. Antibiotic use in
More informationThe evolutionary epidemiology of antibiotic resistance evolution
The evolutionary epidemiology of antibiotic resistance evolution François Blanquart, CNRS Stochastic Models for the Inference of Life Evolution CIRB Collège de France Quantitative Evolutionary Microbiology
More informationQuelle politique antibiotique pour l Europe? Dominique L. Monnet
Quelle politique antibiotique pour l Europe? Dominique L. Monnet National Center for Antimicrobials & Infection Control Statens Serum Institut, Copenhagen, Denmark Opinion of the Section for Protection
More informationrates adjusted for age, sex, infection subclass, and type of antibiotic treatment used) by British Medical Journal Publishing Group
Antibiotic treatment failure in four common infections in UK primary care 1991-2012: longitudinal analysis Craig J Currie BMJ 2014;349:g5493 23 September 2014 More than one in 10 initial antibiotic monotherapies
More informationAMR epidemiological situation: ECDC update
One Health Network on Antimicrobial Resistance (AMR) AMR epidemiological situation: ECDC update Dominique L. Monnet, on behalf of ECDC Antimicrobial Resistance and Healthcare-Associated Infections (ARHAI)
More informationEU Health Priorities. Jurate Svarcaite Secretary General PGEU
EU Health Priorities Jurate Svarcaite Secretary General PGEU Members: Professional Bodies & Pharmacists Associations 2016: 33 Countries Austria Belgium Bulgaria Croatia Cyprus Czech Rep Denmark Estonia
More informationAntimicrobial Resistance. Tackling the Burden in the European Union. Briefing note for EU/EEA countries
Antimicrobial Resistance Tackling the Burden in the European Union Briefing note for EU/EEA countries Antimicrobial Resistance Tackling the Burden in the European Union Contents Key messages 03 Use of
More informationWHO global and regional activities on AMR and collaboration with partner organisations
WHO global and regional activities on AMR and collaboration with partner organisations Dr Danilo Lo Fo Wong Programme Manager for Control of Antimicrobial Resistance Building the AMR momentum 2011 WHO/Europe
More informationEuropean poultry industry trends
European poultry industry trends November 5 th 2014, County Monaghan Dr. Aline Veauthier & Prof. Dr. H.-W. Windhorst (WING, University of Vechta) 1 Agenda The European Chicken Meat Market - The global
More informationOECD WORK ON AMR: TACKLING THE NEGATIVE CONSEQUENCES OF ANTIBIOTIC RESISTANCE ON HUMAN HEALTH. Michele Cecchini OECD Health Division
OECD WORK ON AMR: TACKLING THE NEGATIVE CONSEQUENCES OF ANTIBIOTIC RESISTANCE ON HUMAN HEALTH Michele Cecchini OECD Health Division Antimicrobial Resistance is a Global Threat Modern medicine and surgery
More informationAntimicrobial resistance and antimicrobial consumption in Europe
Antimicrobial resistance and antimicrobial consumption in Europe Dominique L. Monnet, on behalf of ECDC Antimicrobial Resistance and Healthcare-Associated Infections (ARHAI) Programme Vilnius, 28 November
More informationAntimicrobial consumption and resistance in humans in the EU and conclusions from the ECDC-EFSA- EMA JIACRA report
Antimicrobial consumption and resistance in humans in the EU and conclusions from the ECDC-EFSA- EMA JIACRA report Dominique L. Monnet, on behalf of ECDC Antimicrobial Resistance and Healthcare-Associated
More informationAntimicrobial consumption
Antimicrobial consumption Annual Epidemiological Report for 2017 Key facts Twenty-seven countries, comprising 25 EU Member States and two EEA countries (Iceland and Norway) reported data on antimicrobial
More informationAn agency of the European Union
An agency of the European Union Human medicines in 23 Research and development 473 overall number of scientific advice and protocol assistance requests received in 23
More informationPneumococcus: Antibiotic Resistance in the Region
Pneumococcus: Antibiotic Resistance in the Region Çiğdem Bal Kayacan Istanbul University Istanbul Faculty of Medicine Department of Microbiology & Clinical Microbiology Drug Resistance in S.pneumoniae
More informationSafe Patient Care Keeping our Residents Safe Use Standard Precautions for ALL Residents at ALL times
Safe Patient Care Keeping our Residents Safe 2016 Use Standard Precautions for ALL Residents at ALL times #safepatientcare Do bugs need drugs? Dr Deirdre O Brien Consultant Microbiologist Mercy University
More informationPrevention and control of antimicrobial resistance in healthcare settings: raising awareness about best practices
Prevention and control of antimicrobial resistance in healthcare settings: raising awareness about best practices Dominique L. Monnet, on behalf of ECDC Antimicrobial Resistance and Healthcare-Associated
More informationEssayOnDeclawingCatsForStudents
EssayOnDeclawingCatsForStudents In the 1960s many people in America started keeping their cats strictly indoors because the world outside was becoming more dangerous. The only problem was that cats need
More informationHSE - Health Protection Surveillance Centre Surveillance of Antimicrobial Consumption in Ireland
Surveillance of Antimicrobial Consumption in Ireland Ajay Oza A European Study on the Relationship between Antimicrobial Use and Antimicrobial Resistance (1998-1999) Bronzwaer et al 2002 Emerging Infectious
More informationHosted by the Infection Prevention Society A Webber Training Teleclass
Broadcast Live From the Annual Conference of the Infection Prevention Society www.ips.uk.net The only drugs that are: Gary French Guy s & St Thomas Hospital & King s College, London Not directed against
More informationECDC activities on antimicrobial resistance & healthcare-associated infections (ARHAI Programme) Ülla-Karin Nurm, ECDC Tallinn, 13 May 2013
ECDC activities on antimicrobial resistance & healthcare-associated infections (ARHAI Programme) Ülla-Karin Nurm, ECDC Tallinn, 13 May 2013 What is the European Union? 27 Member States 24 official languages
More informationImpact of Antimicrobial Resistance on Human Health. Robert Cunney HSE HCAI/AMR Programme and Temple Street Children s University Hospital
Impact of Antimicrobial Resistance on Human Health Robert Cunney HSE HCAI/AMR Programme and Temple Street Children s University Hospital AMR in Foodchain Conference, UCD, Dec 2014 Sir Patrick Dun s Hospital
More informationWHO s first global report on antibiotic resistance reveals serious, worldwide threat to public health
New WHO report provides the most comprehensive picture of antibiotic resistance to date, with data from 114 countries 30 APRIL 2014 GENEVA - A new report by WHO its first to look at antimicrobial resistance,
More informationHow do people obtain antibiotics in European countries: an overview
How do people obtain antibiotics in European countries: an overview Dominique L. Monnet, Programme Coordinator Senior Expert, Scientific Advice Unit & the National Antimicrobial Resistance Focal Points
More informationSpecial Eurobarometer 478. Summary. Antimicrobial Resistance
Antimicrobial Resistance Survey requested by the European Commission, Directorate-General for Health and Food Safety and co-ordinated by the Directorate-General for Communication This document does not
More informationA Conversation with Dr. Steve Solomon and Dr. Jean Patel on Antimicrobial Resistance June 18 th, 2013
A Conversation with Dr. Steve Solomon and Dr. Jean Patel on Antimicrobial Resistance June 18 th, 2013 Participant List Dr. Steve Solomon, Director, Office of Antimicrobial Resistance, Division of Healthcare
More informationEuropean trends in animal welfare policies and research and their potential implications for US Agriculture
European trends in animal welfare policies and research and their potential implications for US Agriculture Dr. Ed Pajor Associate Professor Director, Center for Animal Well-Being Department of Animal
More information(DRAFT) RECOMMENDATIONS FOR THE CONTROL OF MULTI-DRUG RESISTANT GRAM-NEGATIVES: CARBAPENEM RESISTANT ENTEROBACTERIACEAE
(DRAFT) RECOMMENDATIONS FOR THE CONTROL OF MULTI-DRUG RESISTANT GRAM-NEGATIVES: CARBAPENEM RESISTANT ENTEROBACTERIACEAE John Ferguson (Hunter New England, NSW) on behalf of MRGN Task Force Acknowledgement
More informationESCMID Online Lecture Library. by author
EUCAST and susceptibility testing Europe and beyond Gunnar Kahlmeter EUCAST, ESCMID Antimicrobial susceptibility testing To guide therapy and predict clinical outcome in individual patients (clinical breakpoints)
More informationEFSA s activities on Antimicrobial resistance in the food chain. Dr. Ernesto Liebana Head of BIOCONTAM Unit. EFSA
EFSA s activities on Antimicrobial resistance in the food chain Dr. Ernesto Liebana Head of BIOCONTAM Unit. EFSA EFSA IS The reference body for risk assessment of food and feed in the European Union. Its
More informationAntimicrobial consumption
SURVEILLANCE REPORT Annual Epidemiological Report for 2016 Antimicrobial consumption Key facts Twenty-nine countries, including 27 EU Member States and two EEA countries (Iceland and Norway) reported data
More informationStop overuse of antibiotics in humans rational use
Stop overuse of antibiotics in humans rational use Dominique L. Monnet, Senior Expert and Head of Disease Programme Antimicrobial resistance and Healthcare-associated infections (ARHAI) European Centre
More informationTHE DEVELOPMENT OF A RISK BASED MEAT INSPECTION SYSTEM SANCO / 4403 / 2000
FEDERATION OF VETERINARIANS OF EUROPE FVE/01/034 Final THE DEVELOPMENT OF A RISK BASED MEAT INSPECTION SYSTEM SANCO / 4403 / 2000 Members FVE COMMENTS Austria Belgium Croatia Cyprus Czech Republic Denmark
More informationEuropean Antibiotic Awareness Day: Promoting prudent antibiotic use in Europe
European Antibiotic Awareness Day: Promoting prudent antibiotic use in Europe Dominique L. Monnet, Head of Disease Programme, Antimicrobial Resistance and Healthcare-Associated Infections (ARHAI) Joint
More informationSalmonella monitoring data, food-borne outbreaks and antimicrobial resistance data for 2014 in the European Union
Salmonella monitoring data, food-borne outbreaks and antimicrobial resistance data for 2014 in the European Union Valentina Rizzi BIOMO team, BIOCONTAM Unit, EFSA 21 st EURL-Salmonella workshop 9 June
More informationThese life-saving drugs have been a boon to medical care and benefited hundreds of million patients around the globe.
SINCE Sir Alexander Fleming, a Scottish biologist, pharmacologist and botanist (a 1945 Nobel laureate), first discovered penicillin in 1923, hundreds of more potent wider spectrum antibiotics have been
More informationSummary of the latest data on antibiotic resistance in the European Union
Summary of the latest data on antibiotic resistance in the European Union EARS-Net surveillance data November 2017 For most bacteria reported to the European Antimicrobial Resistance Surveillance Network
More informationThis document is available on the English-language website of the Banque de France
JANUARY 7 This document is available on the English-language website of the www.banque-france.fr Countries ISO code Date of entry into the euro area Fixed euro conversion rates France FR //999.97 Germany
More informationGlobal animal production perspectives and correlated use of antimicrobial agents
Global animal production perspectives and correlated use of antimicrobial agents Barbara Freischem Executive Director, International Federation for Animal Health (IFAH) General Overview Presentation overview
More informationby author ESCMID Online Lecture Library EUCAST The European Committee on Antimicrobial Susceptibility Testing September 2010
EUCAST The European Committee on Antimicrobial Susceptibility Testing September 2010 Gunnar Kahlmeter Chairman of EUCAST Terms and acronyms AST Antimicrobial Susceptibility Testing MIC Minimum Inhibitory
More informationAppendix F: The Test-Curriculum Matching Analysis
Appendix F: The Test-Curriculum Matching Analysis TIMSS went to great lengths to ensure that comparisons of student achievement across countries would be as fair and equitable as possible. The TIMSS 2015
More informationANTIMICROBIAL STEWARDSHIP
ANTIMICROBIAL STEWARDSHIP Australian Pig Veterinarians Annual Conference 11-12 September, 2017 Stephen Page Advanced Veterinary Therapeutics swp@advet.com.au OUTLINE Importance of AMR Antimicrobial use
More informationFoodborne Zoonotic Parasites
Foodborne Zoonotic Parasites Lucy J. Robertson, Norwegian University of Life Sciences, Oslo, Norway Norwegian University of Life Sciences 1 Foodborne pathogens increasing importance?? Increasing awareness
More informationFood & Veterinary Office
EUROPEAN COMMISSION HEALTH & CONSUMER PROTECTION DIRECTORATE-GENERAL Directorate F - Food and Veterinary Office DG(SANCO) F6(2004)D/660037 Food & Veterinary Office Programme of Inspections 2004 July -
More informationLOHMANN TIERZUCHT. The specialist for layer breeding BREEDING FOR SUCCESS TOGETHER
LOHMANN TIERZUCHT The specialist for layer breeding BREEDING FOR SUCCESS TOGETHER European lessons learned from moving an industry to cage- free Presented by: Prof. Dr. Rudolf Preisinger Chicago, April
More informationStratégie et action européennes
Résistance aux antibiotiques : une impasse thérapeutique? Implications nationales et internationales Stratégie et action européennes Dominique L. Monnet, Senior Expert and Head of Disease Programme Antimicrobial
More informationImport Restrictions for Passengers
January 2008 Plants Import from the EU Member States A passenger is allowed to import small quantities of plants, parts thereof, and other plant products such as fruit, vegetables, and seeds for personal
More information03/09/2014. Infection Prevention and Control A Foundation Course. Talk outline
Infection Prevention and Control A Foundation Course 2014 What is healthcare-associated infection (HCAI), antimicrobial resistance (AMR) and multi-drug resistant organisms (MDROs)? Why we should be worried?
More informationIS FACTORY FARMING MAKING US SICK?
Insights paper IS FACTORY FARMING MAKING US SICK? Human resistance to antibiotics: an earnings risk for the global food and beverage sector April 2017 Key points > > Recent scientific studies have linked
More informationUnited Kingdom Veterinary Medicines Directorate Woodham Lane New Haw Addlestone Surrey KT15 3LS DECENTRALISED PROCEDURE
United Kingdom Veterinary Medicines Directorate Woodham Lane New Haw Addlestone Surrey KT15 3LS DECENTRALISED PROCEDURE PUBLICLY AVAILABLE ASSESSMENT REPORT FOR A VETERINARY MEDICINAL PRODUCT (AT, BE,
More informationSpecial Eurobarometer 445. Summary
Survey requested by the European Commission, Directorate-General for Health and Food Safety and co-ordinated by the Directorate-General for Communication This document does not represent the point of view
More informationInitiatives taken to reduce antimicrobial resistance in DK and in the EU in the health care sector
Initiatives taken to reduce antimicrobial resistance in DK and in the EU in the health care sector Niels Frimodt-Møller Professor, MD DMSc Dept. of Clinical Microbiology Hvidovre Hospital, Copenhagen,
More informationAntimicrobial Resistance
Special Eurobarometer 338 Antimicrobial Resistance Fieldwork: November - December 2009 Publication: April 2010 Summary Eurobarometer 338/Wave 72.5 TNS Opinion & Social Survey commissioned by the Directorate-General
More informationStaphylococcus aureus and Health Care associated Infections
Staphylococcus aureus and Health Care associated Infections Common - but poorly measured Prof Peter Collignon The Canberra Hospital Australian National University What are health-care associated infections?
More informationMDRO in LTCF: Forming Networks to Control the Problem
MDRO in LTCF: Forming Networks to Control the Problem Suzanne F. Bradley, M.D. Professor of Internal Medicine Division of Infectious Disease University of Michigan Medical School VA Ann Arbor Healthcare
More information«Antibiotic Stewardship» programmes & antibiotic resistance
«Antibiotic Stewardship» programmes & antibiotic resistance Winfried V. Kern Abteilung Infektiologie Universitätsklinikum Freiburg www.if-freiburg.de Agenda Definition Healthcare quality & patient safety
More informationChart showing the average height of males and females in various world countries.
Chart showing the average height of males and females in various world countries. Country/Region Average male height Average female height Sampled Age Range Albania 174.0 cm (5 ft 8 1/2 in) 161.8 cm (5
More informationPunto di vista dell EFSA e raccolta dati Valentina Rizzi Unit on Biological Monitoring (BIOMO)
Committed since 2002 to ensuring that Europe s food is safe Punto di vista dell EFSA e raccolta dati Valentina Rizzi Unit on Biological Monitoring (BIOMO) Corso di formazione Gestione per il contenimento
More informationChanging patterns of poultry production in the European Union
Chapter 2 Changing patterns of poultry production in the European Union H-W. Windhorst Abstract The EU (27) is one of the leading global regions in egg and poultry meat production. Production is, however,
More informationThe threat of multidrug-resistant microorganisms and how to deal with it in Europe
The threat of multidrug-resistant microorganisms and how to deal with it in Europe Dominique L. Monnet, Senior Expert and Head of Disease Programme Antimicrobial resistance and Healthcare-associated infections
More informationTackling the need for new antibacterial drugs
Tackling the need for new antibacterial drugs Wendy Lawson Lead Pharmacist, Infectious Diseases Imperial College Healthcare NHS Trust, London & Antibiotic Action Champion Timeline of Antibiotic Discovery
More informationHow is Ireland performing on antibiotic prescribing?
European Antibiotic Awareness Campaign 2016 November Webinar Series on Antibiotic Prescribing How is Ireland performing on antibiotic prescribing? Dr Rob Cunney National Clinical Lead HCAI AMR Clinical
More informationAntimicrobial Cycling. Donald E Low University of Toronto
Antimicrobial Cycling Donald E Low University of Toronto Bad Bugs, No Drugs 1 The Antimicrobial Availability Task Force of the IDSA 1 identified as particularly problematic pathogens A. baumannii and
More informationKeeping Antibiotics Working: Nursing Leadership in Action
Keeping Antibiotics Working: Nursing Leadership in Action Pat McLaine, DrPH, MPH, RN Robyn Gilden, PhD, RN Department of Family and Community Health Maryland Nurses Association October 2016 US 2 million
More informationAnnual report of the Scientific Network on BSE-TSE 2015
TECHNICAL REPORT APPROVED: 10 December 2015 PUBLISHED: 11 December 2015 Annual report of the Scientific Network on BSE-TSE 2015 Abstract European Food Safety Authority The EFSA Scientific Network on bovine
More informationIMPORT HEALTH STANDARD FOR THE IMPORTATION INTO NEW ZEALAND OF RABBIT MEAT FOR HUMAN CONSUMPTION FROM THE EUROPEAN COMMUNITY
IMPORT HEALTH STANDARD FOR THE IMPORTATION INTO NEW ZEALAND OF RABBIT MEAT FOR HUMAN CONSUMPTION FROM THE EUROPEAN COMMUNITY ANNEX A ASSIGNED NUMBERS (AN): 4C.2, 4D.1, 5C.2, 5D.1, 6C.1, 6D.2, Issued pursuant
More informationAntimicrobial Resistance Prevention (Action Package: Prevent-1) Putting AMR on the priority list: Sweden Dr. Nils Anders Tegnell, Director, The
Antimicrobial Resistance Prevention (Action Package: Prevent-1) Putting AMR on the priority list: Sweden Dr Nils Anders Tegnell, Director, The Public Health Agency of Sweden The Global Challenge Antibiotics
More informationCarbapenemase-producing Enterobacteriaceae (CRE) T H E L A T E S T I N T H E G R O W I N G L I S T O F S U P E R B U G S
Carbapenemase-producing Enterobacteriaceae (CRE) T H E L A T E S T I N T H E G R O W I N G L I S T O F S U P E R B U G S CRE Enterobacteriaceae (Gram Negative Bacilli) Citrobacter species Escherichia coli***
More informationANNEX. to the COMMISSION IMPLEMENTING DECISION
EUROPEAN COMMISSION Brussels, 30.4.2015 C(2015) 3024 final ANNEX 1 ANNEX to the COMMISSION IMPLEMENTING DECISION on the adoption of the multiannual work programme for 2016-2017 for the implementation of
More informationCouncil Conclusions on Antimicrobial Resistance (AMR) 2876th EMPLOYMENT, SOCIAL POLICY, HEALTH AND CONSUMER AFFAIRS Council meeting
COUNCIL OF THE EUROPEAN UNION Council Conclusions on Antimicrobial Resistance (AMR) 2876th EMPLOYMT, SOCIAL POLICY, HEALTH AND CONSUMER AFFAIRS Council meeting Luxembourg, 10 June 2008 The Council adopted
More informationWHO laboratory-based global survey on multidrug-resistant organisms (MDROs) in health care interim analysis
WHO laboratory-based global survey on multidrug-resistant organisms (MDROs) in health care interim analysis Aim: to estimate the burden of MDROs isolated among inpatients in a wide range of health-care
More informationDr Nata Menabde Executive Director World Health Organization Office at the United Nations Global action plan on antimicrobial resistance
Global action plan on antimicrobial resistance Dr Nata Menabde Executive Director World Health Organization Office at the United Nations Proportion of MDR among previously treated TB cases, 1994-2010 0-
More informationFood & Veterinary Office
EUROPEAN COMMISSION HEALTH & CONSUMER PROTECTION DIRECTORATE-GENERAL Directorate F - Food and Veterinary Office DG(SANCO)D(2005)660066 Food & Veterinary Office Programme of Inspections 2005 July - December
More informationEFSA s activities on Antimicrobial Resistance
EFSA s activities on Antimicrobial Resistance CRL-AR, Copenhagen 23 April 2009 Annual Workshop of CRL - AR 1 Efsa s Role and Activities on AMR Scientific advices Analyses of data on AR submitted by MSs
More informationClinical Guideline. District Infectious Diseases Management. Go to Guideline. District Infectious Diseases Management CG 18_24
Clinical Guideline District Infectious Diseases Management Sites where Clinical Guideline applies All facilities This Clinical Guideline applies to: 1. Adults Yes 2. Children up to 16 years Yes 3. Neonates
More informationINDEPENDENT REVIEW OF DISPENSING
FEDERATION OF VETERINARIANS OF EUROPE FVE/00/050 INDEPENDENT REVIEW OF DISPENSING FVE CONTRIBUTION Members Austria Belgium Croatia Cyprus Czech Republic Denmark Estonia Finland France FYROM Germany Greece
More informationRULES & REGULATIONS EUKANUBA WORLD CHALLENGE 2019 Birmingham March 7th
RULES & REGULATIONS EUKANUBA WORLD CHALLENGE 2019 Birmingham March 7th 1. About the event The Eukanuba World Challenge ( EWC ) is a dog competition taking place once a year. The event has been designed
More informationCampylobacter infections in EU/EEA and related AMR
Campylobacter infections in EU/EEA and related AMR Therese Westrell, ECDC EURL Campylobacter workshop, Uppsala, Sweden, 9 October 2018 Zoonoses Zoonotic infections in the EU, 2016 Campylobacteriosis (N
More informationSurveillance of AMR in PHE: a multidisciplinary,
Surveillance of AMR in PHE: a multidisciplinary, integrated approach Professor Neil Woodford Antimicrobial Resistance & Healthcare Associated Infections (AMRHAI) Reference Unit Crown copyright International
More informationPreventing Multi-Drug Resistant Organism (MDRO) Infections. For National Patient Safety Goal
Preventing Multi-Drug Resistant Organism (MDRO) Infections For National Patient Safety Goal 07.03.01 2009 Methicillin Resistant Staphlococcus aureus (MRSA) About 3-8% of the population at large is a carrier
More informationAppendix F. The Test-Curriculum Matching Analysis Mathematics TIMSS 2011 INTERNATIONAL RESULTS IN MATHEMATICS APPENDIX F 465
Appendix F The Test-Curriculum Matching Analysis Mathematics TIMSS 2011 INTERNATIONAL RESULTS IN MATHEMATICS APPENDIX F 465 TIMSS went to great lengths to ensure that comparisons of student achievement
More informationREPORT ON POINT PREVALENCE SURVEY OF ANTIMICROBIAL PRESCRIPTION IN EUROPEAN NURSING HOMES, November 2009
REPORT ON POINT PREVALENCE SURVEY OF ANTIMICROBIAL PRESCRIPTION IN EUROPEAN NURSING HOMES, November 29 ESAC-3: Nursing Home Subproject Group Broex E, Jans B, Latour K, Goossens H and the ESAC management
More informationPOTENTIAL STRUCTURE INDICATORS FOR EVALUATING ANTIMICROBIAL STEWARDSHIP PROGRAMMES IN EUROPEAN HOSPITALS
POTENTIAL STRUCTURE INDICATORS FOR EVALUATING ANTIMICROBIAL STEWARDSHIP PROGRAMMES IN EUROPEAN HOSPITALS Dirk VOGELAERS Department of General Internal Medicine, Infectious Diseases and Psychosomatic Medicine
More informationSCIENTIFIC REPORT. Analysis of the baseline survey on the prevalence of Salmonella in turkey flocks, in the EU,
The EFSA Journal / EFSA Scientific Report (28) 198, 1-224 SCIENTIFIC REPORT Analysis of the baseline survey on the prevalence of Salmonella in turkey flocks, in the EU, 26-27 Part B: factors related to
More informationMDR Acinetobacter baumannii. Has the post antibiotic era arrived? Dr. Michael A. Borg Infection Control Dept Mater Dei Hospital Malta
MDR Acinetobacter baumannii Has the post antibiotic era arrived? Dr. Michael A. Borg Infection Control Dept Mater Dei Hospital Malta 1 The Armageddon recipe Transmissible organism with prolonged environmental
More informationEpidemiology and Economics of Antibiotic Resistance
Epidemiology and Economics of Antibiotic Resistance Eili Y. Klein February 17, 2016 Health Watch USA Meeting I. The burden of antibiotic resistance is a growing global threat, but hard numbers are lacking
More informationImagine. Multi-Drug Resistant Superbugs- What s the Big Deal? A World. Without Antibiotics. Where Simple Infections can be Life Threatening
Multi-Drug Resistant Superbugs- What s the Big Deal? Toni Biasi, RN MSN MPH CIC Infection Prevention Indiana University Health Imagine A World Without Antibiotics A World Where Simple Infections can be
More informationBSAC antimicrobial susceptibility
BSAC antimicrobial susceptibility testing - from Stokes to European harmonization to world? Derek Brown 23 March 2011 BSAC antimicrobial susceptibility testing ti pre-working Party BSAC meetings from the
More informationCombating Antimicrobial Resistance: The Way Forward
Combating Antimicrobial Resistance: The Way Forward James M. Hughes, MD Professor of Medicine and Public Health Emory University Atlanta, GA NIAA Antibiotic Symposium November 14, 2014 Disclosure No conflicts
More informationAntibiotic resistance is one of the biggest threats to global health, food security, and development today.
Antibiotic resistance Fact sheet Updated November 2017 Key facts Antibiotic resistance is one of the biggest threats to global health, food security, and development today. Antibiotic resistance can affect
More information