I have provided opinion and advice to a variety of agencies, including the UK, Scottish and Welsh governments.

Transcription

1 MICHAEL STEAR Present Position: Professor of Animal Biology at AgriBio, Department of Animal, Plant and Soil Sciences since June The aim of my research is to understand the mechanisms underlying variation among livestock in resistance to infection and to use this understanding to develop better methods of controlling disease and the effects of subclinical infection. We are particularly interested in genetic variation in immune responses to parasites of cattle, sheep and fish. Our research includes epidemiology, genetics, immunology, pathology, host-parasite coevolution and mathematical modelling. Professional Experience: Professor, Institute of Biodiversity, Animal Health and Comparative Medicine, University of Glasgow from (Senior Research Fellow since 1990). I led a multidisciplinary, multi-centre research group studying disease susceptibility in livestock and fish. My grants supported 14 scientists and administrators and the team was one of the largest and most successful in the University of Glasgow. Førsteamanuensis in the Department of Animal Genetics, National Veterinary Institute, Oslo, Norway, I developed molecular methods to identify bulls that would transmit superior disease resistance to their calves. Visiting Professor, Department of Genetics and Breeding, Roman L. Hruska U.S. Meat Animal Research Center, United States, Department of Agriculture, I was recruited to lead the Genetics of Disease Resistance project comprising three scientists and four technicians. Research Fellow and Faculty member in the Department of Immunology, The John Curtin School of Medical Research, The Australian National University, A.C.T I led the bovine immunogenetics group compromising one post-doctoral research assistant, two PhD students, one full-time and several part time technicians. I have also held visiting professor appointments at several universities including the University of Oslo, Louisiana State University, University of Nebraska, Pennsylvania State University, the University of Sydney and Curtin University of Technology. In recent years I have collaborated with scientists from Australia (Professors Raadsma and Nicholas, University of Sydney, Dr Groth, Curtin University of Technology); Canada (Professor Mallard, University of Guelph, Dr Ellis, University of Sakatchewan); France (Drs Moreno, Cabaret INRA, Dr Jacquiet, Ecole Nationale Veterinaire de Toulouse); Germany (Dr Buitkamp, Institut fuer Tierzucht, Bayerische Landesanstalt fuer Landwirtschaft); Italy (Drs Casu, Carta, Instituto Zootecnico e Caseario par la Sardegna); Poland (Dr Moskwa Polish Academy of Sciences, Professor Doligalska and Dr Donskow, University of Warsaw); Spain (Professors Arranz, Rojo Dr Gutierrez-Gil, University of Leon; Dr J. Gonzalez and Dr Conde, University of las Palmas de Gran Canaria). Education: University of Edinburgh/Animal Breeding Research Organisation, PhD Thesis title "Lymphocyte Antigens in Sheep". Supervisors Dr. K James and Dr. R L Spooner. Aberdeen University, Graduated BSc (Honours 2. 1) in Genetics. Teaching: I have taught courses on Immunology (BAgSci), Proteins, DNA and Basic Genetics (BSc), Statistics (BSc), Bioinformatics (BSc), Masters in Research Bioinformatics. I also supervise student projects as well as setting and marking essays in various undergraduate courses including Parasitology, Genetics, Zoology and Veterinary Biosciences. In recent years, I have taught Animal Breeding and Evolution in the Animal Husbandry Course, Lipid Metabolism (BVMS), Stastistics, Protein Biochemistry (Veterinary Biosciences) Animal Genetics (Masters in Veterinary Public 1

2 Health). I was responsible for setting up courses BSc Veterinary Biosciences degree Proteins, DNA and Basic Genetics, Statistics and Bioinformatics. I also administered these courses for the first four years of the new degree course. I have acted as an external examiner on several undergraduate courses, most recently 3 from the University of Liverpool BVMS degree (Molecular Biology and Genetics, Animal Breeding and Research Projects). I have also run postgraduate courses in Statistics, Bioinformatics, Genetics and Animal Breeding as well as Preparation of Scientific Papers and Grants in several countries including Spain, Germany, Poland, UK and USA. In addition, I deliver 5-10 invited lectures a year at Conferences, Workshops and scientific departments. I have supervised over 20 postgraduate students; all of these students have graduated except one who withdrew for medical reasons (Pott s disease). In the last 2 years, I have examined PhD theses in France (2), Spain, Ireland, Australia (2) and the UK (4). These theses have been in a variety of subjects including animal science, genetics, immunology, parasitology and statistics. Nationality: British Languages: A reading knowledge of French, German and Norwegian. Learned Societies: British Society of Immunology, British Society of Parasitology, Genetics society (UK), International Society of Animal Genetics and the Association of Veterinary Teachers and Research Workers. Grants: Over 12,000,000 has been awarded from a variety of sources including the European Commission, Biotechnology and Biological Sciences Research Council, Department for International Development, Wellcome Trust, Meat and Livestock Commission, Milk Development Council, Ministry of Agriculture, Food and Fisheries, the Scottish Office, United States Department of Agriculture and the United States Agency for International Development. A list of grants held is attached. Other Professional Activities: I have given lectures and seminars to a wide variety of audiences including scientists, veterinarians, farmers and laymen. In particular, I have given plenary lectures to international conferences on animal and veterinary science, genetics, immunology and parasitology. I am a section editor for Animal and an editor of Parasitaria (a new journal set up by the Spanish Society of Parasitology). I have provided opinion and advice to a variety of agencies, including the UK, Scottish and Welsh governments. Manuscripts have been reviewed for a number of international journals including Acta Parasitologica, Animal Genetics, Animal Health Research Reviews, Animal Science, Diseases of Aquatic Organisms, European Journal of Immunogenetics,Experimental Parasitology, Immunogenetics, International Journal for Parasitology, International Journal of Immunogenetics, Journal of Animal Science, Journal of Dairy Science, Journal of Helminthology, Journal of Parasitology, Livestock Science,Parasite, Parasitology International, Parasitology, Parasitology Research, Parasite Immunology, PLOS One, Research in Veterinary Science, Small Ruminant Research, Trends in Ecology and Evolution, Trends in Parasitology, Tissue Antigens, Vaccine, Veterinary Immunology and Immunopathology, The Veterinary Journal, Veterinary Research and Veterinary Parasitology. 2

3 Funding proposals have been assessed on behalf of international and national agencies in Australia, Belgium, Canada, Germany, Kazakhstan, New Zealand, Norway, Poland, Qatar, United Kingdom and United States. Honours and Awards Visiting Professor Curtin University 2016 Fellow of the Royal Society for Biology 2012 Member BBSRC Pool of Experts Section Editor Animal 2012 Editorial Advisory Board The Open Veterinary Science Journal 2011 Editorial Advisory Board The Open Parasitology Journal 2010 Member Australian Research Council Pool of Experts 2009 Visiting Professor Pennsylvania State University 2007 Associate Editor The Veterinary Journal 2008 Visiting Professor University of Sydney 1997 Visiting Professor, Louisiana State University 1990 Visiting Professor University of Oslo 1989 Faculty Associate, Center for Biotechnology, University of Nebraska 1988 Graduate Faculty Member, University of Nebraska 1987 Visiting Professorship University of Nebraska Honorary Member Department of Animal Husbandry University of Sydney 1984 Research Fellowship Australian National University Royal Society Research Fellowship award for study overseas 1980 (Declined). Agriculture Research Council Post-graduate Scholarship First in Class in Immunology Aberdeen University First in Class in Genetics Aberdeen University Grants: Acute phase protein as biomarkers of disease in livestock and aquaculture BB/M022021/ BBSRC Follow on Fund 200, The influence of selective breeding on MHC diversity. BB/L004070/ BBSRC Development of a high-density salmon SNP chip: a key tool for improving the competitiveness and sustainability of the UK salmon farming industry. TSB: 1010_CRD_BIO_GEN_ ,339 Glasgow Share 7, New approaches to innate immunity in livestock and the potential for manipulation Meat and Livestock Australia Glasgow share 22,700. Wellcome Trust CVRT awards 2,000 each 2011, 2012, 2013 A systems biology approach to controlling nematode infections in livestock. Marie Curie ITN E3,300, Why some hosts have high parasite burdens and the implications for the design of sustainable control strategies. 172,523 The Wellcome Trust The feasibility of breeding Atlantic salmon for resistance to sea-lice DEFRA Feasibility Link Scheme 69,919 The feasibility of breeding Atlantic salmon for resistance to sea-lice Landcatch Natural Selection Ltd 15,000 Wellcome Trust Biomedical Vacation Scholarship 1440 The effect of selection for nematode resistance on MHC class II diversity. BB/F015313/ BBSRC Mechanisms regulating the dynamics of a parasite community in a wild herbivore system. Human Frontier Science Program. $1,500,000. Glasgow share $650, DNA markers for improving sheep health. Quality Meat Scotland, 68, The potential role of phagocytic cells in resistance to scrapie in sheep. Royal Society Fellowship to Dr F. Houston. 201,820 3

4 Integration of Functional Genomics and Immunology and their Application to Infectious Disease in Ruminants DEFRA 5,400,000. Glasgow share 500, Identification and DNA analysis of nematode derived chemokine - MCP-1 in Heligmosomoides polygyrus. British Council, 1,059 awarded February DNA arraying system for direct haplotyping to predict genetics in sheep and cattle. Department of Trade and Industry, UK/Texas Bioscience Collaboration Programme: 6,000 awarded March Marker Assisted Selection for Disease Resistance in Scottish Blackface Sheep, Genesis/Faraday BBSRC 5,000 awarded August Dynamics of a parasite community in an age-structured wild population. The Royal Society 479,609 awarded March Veterinary Research Training Fellowships in Quantitative Epidemiology. DEFRA 1,900,000. Glasgow share 1,000, Using genetics to improve the quality and safety of sheep products. Commission of the European Community 1,320,002 Euro Mapping bovine genes for disease resistance and health MAFF, MLC, MDC, BBSRC. 2,081,000 with J. L. Fitzpatrick, J. L. Williams and J. Woolliams (Glasgow share 251,000). Genetic improvement of resistance to nematodes in terminal sire sheep SOAEFD, MLC,BBSRC 271,800 with S. C. Bishop (Glasgow share 182,000). Breeding cattle for mastitis resistance MDC 93,000 with J. L. Fitzpatrick Optimising milk production on smallholder dairy farms in Tanzania DFID 326,000 with J. L. Fitzpatrick, M. P. Bryant and N. P. French The identification of productive and nematode resistant sheep. ODA RNRRS Livestock Production Programme 120,000 with S. C. Bishop and Q. A. McKellar The evaluation of anti-parasite IgA responses as a marker of nutritional inadequacy during gastrointestinal nematode infection of small ruminants. ODA RNRRS Animal Health Programme 80,000 with J. M. Maclean Genetic Characterisation of West African Cattle. Commission of the European Communities. STD 3 DG XII 637,511 ecu with Dr. D Bradley, Dr. R Sow, and Dr. Ngere The Interaction between Nutrition and Genetic Resistance to Parasitic Disease. ODA/NRED Animal Health Programme. 286,436 with P H Holmes, J L Duncan, J J Parkins, Q A McKellar Towards a Major Gene for Neutrophil Function. AFRC 44, Genetic Control of Resistance to Gastrointestinal Nematodes in Sheep. The Wellcome Trust Visiting Fellowship for Professor E. Sinski. 16,543 with J L Duncan, P H Holmes, A Tait The Donkey Major Histocompatibility Complex and Disease Susceptibility. The Donkey Sanctuary 116, The Interaction between Nutrition and Genetic Resistance to Trypanosomiasis in Trypanotolerant Livestock. Commission of the European Communities. 420,000 ecu with P H Holmes, D Clifford and M Gill Control of Parasitic Diseases. EC Tempus grant. 241,800 ecu with W Hendrickx, P H Holmes and A Tait Genetic control of histological responses to infection with ovine gastric nematodes AFRC Veterinary Research Fellowship (with Professor S. Love) BoLA testing in dairy cattle. C$20,000. Canadian Association of Animal Breeders with Dr. T R Batra. Agriculture Canada Genetic resistance to disease. $1,200,000 with Drs. N E Muggli, R T Stone, U.S.D.A. CRIS S B. abortus vaccination and immune response genes in beef cattle. $136,334. U.S.D.A. Special Grant 86-CRSR with Drs. M J Newman, D D French The Genetic basis of parasite resistance in African sheep AID/USDA/CSRS $90,000 with Dr. J Miller

5 Publications: Peer-reviewed journals (6346 citations, H-index 48 on 31/01/2017) 1. Spooner, R. L., Oliver, R. A., Sales, D. I., McCoubrey, C. M., Millar, P., Morgan, A. G., Amorena, B., Bailey, E., Bernoco, D., Brandon, M., Bull, R. W., Caldwell, J., Cwik, S., van Dam, R. H., Dodd, J., Gahne, B., Grosclaude, F., Hall, J. G., Hines, H., Leveziel, H., Newman, M. J., Stear, M. J., Stone, W. H. and Vaiman, M. Analysis of alloantisera against bovine lymphocytes. Joint report of the 1st International Bovine Lymphocyte Antigen (BoLA) Workshop. Animal Blood Groups and Biochemical Genetics 10: Stear, M. J. and Spooner, R. L. Lymphocyte antigens in sheep. Animal Blood Groups and Biochemical Genetics 12: Newman, M.J., Campion, J. E. and Stear, M.J. Mixed lymphocyte reactivity in cattle. Tissue Antigens 20: Stear, M.J., Allen, D. and Spooner, R. L. A method of freezing sheep lymphocytes prior to cytoxicity testing. Tissue Antigens 19: Stear, M.J., Newman, M.J. and Nicholas, F.W. Two closely linked loci and one apparently independent locus code for bovine lymphocyte antigens. Tissue Antigens 20: Newman, M. J. and Stear, M. J. The antibody response to bovine lymphocyte alloantigens. Veterinary Immunology and Immunopathology 4: Stear, M. J. and Spooner, R. L. The occurrence of cytotoxic antilymphocyte antibodies in sheep. Research in Veterinary Science 34: Stear, M.J. and Bell, K. Relationships between the bovine major histocompatibility system and commonly recognised erythrocyte and serum polymorphisms. Animal Blood Groups and Biochemical Genetics 15: Stear, M. J., Newman, M. J., Nicholas, F. W., Brown, S. C. and Holroyd, R. G. Tick resistance and the major histocompatibility system. Australian Journal of Experimental Biology and Medical Science 62: Stear, M.J., Lyons, I., Dufty, J. H., Nicholas, F.W. and Brown, S.C. A comparison of bovine lymphocyte antigens. Animal Blood Groups and Biochemical Genetics 16: Stear, M. J., Outteridge, P. M., Dufty, J. H., Nicholas, F. W. and Tucker, E. M. Antibodies to ovine lymphocytes exist in bovine alloantisera. Experimental and Clinical Immunogenetics 3: Groth, D. M., Wetherall, J. D., Outteridge, P. M. and Stear, M. J. Class I major histocompatibility complex antigens and C4 concentrations in sheep plasma. Animal Genetics 18: Stear, M. J., Brown, S. C., Dimmock, C. K., Dufty, J. H., Hetzel, D. J. S., Mackie, J. T., Nicholas, F. W., Tierney, T. J. and Wetherall, J. D. Breed differences in the frequency of bovine lymphocyte antigens. Experimental and Clinical Immunogenetics 4: Stear, M. J. and Mackie, J. T. Joint inheritance of bovine major histocompatibility system antigens W6 and W11. Animal Genetics 18: Stear, M. J., Tierney, T. J., Baldock, F. C., Brown, S. C., Nicholas, F. W. and Rudder, T. H. Class I antigens of the bovine major histocompatibility system are weakly associated with variation in faecal worm egg counts in naturally infected cattle. Animal Genetics 19: Stear, M. J., Pokorny, T. S. Muggli, N. E. and Stone, R. T. Breed differences in the distribution of BoLA-A locus antigens in American cattle. Animal Genetics 19:

6 17. Stear, M. J., Dimmock, C. K.,., Newman, M.J. and Nicholas, F.W. BoLA antigens are associated with increased frequency of persistent lymphocytosis in bovine leukaemia virus infected cattle and with increased incidence of antibodies to bovine leukaemia virus. Animal Genetics 19: Stear, M. J., Tierney, T. J., Baldock, F. C., Brown, S. C., Nicholas, F. W. and Rudder, T. H. Failure to find an association between Class I antigens of the bovine major histocompatibility system and faecal worm egg counts. International Journal for Parasitology 18: Mackie, J. T. and Stear, M. J. The serological definition of bovine major histocompatibility system class II gene products. Animal Genetics 19: Suppl. 1, pp Muggli, N. E., Stone, R. T. and Stear, M. J. Identification of a bovine DR Beta-like bovine pseudogene and the construction of probes for the definition of RFLPs of cattle. Animal Genetics 19: Suppl. 1, pp Stear, M. J. Associations of BoLA with disease susceptibility and reduced growth rate. Animal Genetics 19: Suppl. 1, pp Mackie, J. T., Bath, M. L., Stear, M. J. and Davis, W. C. Monoclonal antibodies to bovine major histocompatibility system antigens. Experimental and Clinical Immunogenetics 6: Stear, M. J., Nicholas, F. W., Brown, S. C. and Holroyd, R. G. Class I antigens of the bovine major histocompatibility system and resistance to the cattle tick (Boophilus microplus) assessed in three different seasons. Veterinary Parasitology 31: Stear, M. J., Pokorny, T. S., Muggli, N. E. and Stone, R. T. The relationships of birth weight, preweaning gain and postweaning gain with the bovine major histocompatibility system. Journal of Animal Science 67: Batra, T. R., Lee, A. J., Gavora, J. S. and Stear, M. J. Class I alleles of the bovine major histocompatibility system and their association with economic traits. Journal of Dairy Science 72: Stear, M. J., Mallard, B. A., Newman, M. J. and Wilkie, B. N. The current status of major histocompatibility system definition in cattle, goats, horses, pigs and sheep. (Invited review). International Journal of Animal Science 4: Stear, M. J., Hetzel, D. J. S., Brown, S. C., Gershwin, L. J., Mackinnon, M. J. and Nicholas, F. W. The relationships among ecto and endoparasite levels, class I antigens of the bovine major histocompatibility system, immunoglobulin E levels and weight gain. Veterinary Parasitology 34: Stear, M. J., Spradbrow, P. B., Tierney, T. J., Nicholas, F. W. and Bellows, R. A. Failure to find an association between ocular squamous cell carcinoma and class I antigens of the bovine major histocompatibility system. Animal Genetics 20: Stear, M. J., Pokorny, T. S., Echternkamp, S. E. and Lunstra, D. D. The influence of the BoLA-A locus on reproductive traits in cattle. Journal of Immunogenetics 16: Bull, R. W., Lewin, H. A., Wu, M. C., Peterbaugh, K., Antczak, D., Bernoco, D., Cwik, S., Dam, L., Davies, C., Dawkins, R. L., Dufty, J. H., Gerlach, J., Hines, H. C., Lazary, S., Leibold, W., Leveziel, H., Lie, O., Lindberg, P. G., Meggiolaro, D., Meyer, E., Oliver, R., Ross, M., Simon, M., Spooner, R. L., Stear, M. J., Teale, A. and Templeton, J. Joint Report on the Third International Bovine Lymphocyte Antigen (BoLA) Workshop, Helsinki, Finland 27 July Animal Genetics 20:

7 31. Mackie, J.T. and Stear, M.J. The definition of five B lymphocyte alloantigens closely linked to BoLA class I antigens. Animal Genetics 21: Weigel, K. A., Freeman, A. E., Kehrli, M. E., Stear, M. J. and Kelley, D. H. Association of class I bovine lymphocyte antigen complex alleles with health and production traits in dairy cattle. Journal of Dairy Science 73: Stear, M. J., Pokorny, T. S., Fryda-Bradley, S., Lie, O. and Bull, R. W. Genetic analysis of the antigens defined at the third international BoLA workshop. Journal of Immunogenetics 17: Weigel, K. A., Kehrli, M. E., Jr., Thurston, J. R., Stear, M. J., Freeman, A. E. and Kelley, D. H. Association of class I bovine lymphocyte antigen complex alleles with in vitro blood neutrophil functions, lymphocyte blastogenesis, serum complement and conglutinin levels in dairy cattle. Veterinary Immunology and Immunopathology 27: Dietrich, M. A., Truax, R. E., French, D. D., Lea, D. F., Stear, M. J. and Newman, M. J. Measurement of antibody binding to intact bacteria using flow cytometric techniques. Journal of Microbiological Methods 13: Mackie, J.T. and Stear, M.J. Preparation of B lymphocyte-specific alloantisera by skin implant immunisation of cattle. Veterinary Immunology and Immunopathology 30: Barrie, J., Watson, T. D. G, Stear, M.J. and Nash, A. S. Plasma cholesterol and lipoprotein concentrations in the dog: The effects of age, breed gender and endocrine disease. Journal of Small Animal Practice 34: Mejdell, C. M., Lingaas, F., Stear, M. J. and Lie. Genetic analysis of major histocompatibility complex class I antigens, serum transferrins and red blood cell antigens in Norwegian breeds of cattle. Acta Agriculture Scandinavica A 43: Schukken, Y. H., Mallard, B. A., Dekkers, J. C. M., Leslie, K. E. and Stear, M. J. Genetic impact on the risk of intramammary infection following Staphylococcus aureus challenge. Journal of Dairy Science 77: Batra, T. R., Stear, M. J. and Macdonald P. A. Association of class I bovine lymphocyte antigens with production traits in the Ayrshire breed. Canadian Journal of Animal Science 74: Stear M. J. and Murray M. Genetic resistance to Parasitic Disease. Veterinary Parasitology 54: Wallace, D. S., Bairden, K., Duncan, J. L., Fishwick, G., Gill, E. M., Holmes, P. H., McKellar, Q. A., Murray, M., Parkins J. J. and Stear., M. J. Influence of dietary soyabean meal supplementation on resistance to haemonchosis in Hampshire Down lambs. Research in Veterinary Science Stear, M.J., Bishop, S. C., Duncan, J. L., McKellar, Q. A. & Murray, M. The repeatability of faecal egg counts, peripheral eosinophil counts, and plasma pepsinogen concentrations during deliberate infection with Ostertagia circumcincta. International Journal for Parasitology Sinski, E., Bairden, K., Duncan, J. L., Eisler, M. C., Holmes, P. H., McKellar, Q. A., Murray M. & Stear, M. J. Local and plasma antibody responses to the parasitic larval stages of the abomasal nematode Ostertagia circumcincta Veterinary Parasitology Stear, M. J., Bairden, K., Bishop, S. C., Duncan, J. L., Karimi, S. K., McKellar, Q. A. & Murray, M. Different patterns of faecal egg output following infection of Scottish Blackface lambs with Ostertagia circumcincta. Veterinary Parasitology

8 46. Stear, M. J., Bairden, K., Duncan, J. L. & Murray M. A comparison of the responses to repeated, experimental infections with Haemonchus contortus among Scottish Blackface lambs. Veterinary Parasitology Stear, M. J., Bairden, K., Duncan, J. L., Gettinby, G. McKellar, Q. A., Murray M. and Wallace, D. S. The distribution of faecal nematode egg counts in Scottish Blackface lambs following natural, predominantly Ostertagia circumcincta infection. Parasitology Schwaiger, F.-W. Gostomski, D., Stear, M. J., Duncan, J. L., McKellar, Q. A., Epplen J. T. and Buitkamp J. An ovine major histocompatibility complex DRB1 allele is associated with low faecal egg counts following natural, predominantly Ostertagia circumcincta infection. International Journal for Parasitology Mallard, B. A., Leslie, K. E., Dekkers, J. C. M., Hedge, R., Bauman, M. and Stear, M. J. Differences in bovine lymphocyte antigen associations between immune responsiveness and risk of disease following intramammary infection with Staphylococcus aureus. Journal of Dairy Science 78: Scott, I. Stear, M. J. and McKellar, Q. A. A comparison of four methods for the determination of plasma pepsinogen concentration. Research in Veterinary Science 59: Stear, M. J., Bishop, S. C., Doligalska, M., Duncan, J. L., Holmes, P. H., Irvine, J., McCririe, L., McKellar, Q. A., Sinski, E. and Murray, M. Regulation of egg production, worm burden, worm length and worm fecundity by host responses in sheep infected with Ostertagia circumcincta. Parasite Immunology 17: Garrido, J. J. and Stear, M. J. Serologically-defined lymphocyte alloantigens in Spanish sheep. Experimental and Clinical Immunogenetics Newman, M. J., Truax, R. E., French, D. D., Dietrich, M. A., Franke, D. and Stear, M. J. Evidence for genetic control of vaccine-induced antibody responses in cattle. Veterinary Immunology and Immunopathology 50: Wallace, D. S., Bairden, K., Duncan, J. L., Fishwick, G., Gill, M., Holmes, P. H., McKellar, Q. A., Murray, M., Parkins J. J. and Stear M. J. Influence of Dietary Soyabean meal Supplementation on Resistance of Scottish Blackface lambs to haemonchosis. Research in Veterinary Science 60: Mugambi, J. M., Wanyangu, S. W., Bain, R. K., Owango, M. O., Duncan, J. L. and Stear, M. J. Response of Dorper and Red Maasai lambs to trickle Haemonchus contortus infections. Research in Veterinary Science 61: Hunter, N., Foster, J. D., Goldmann, W., Stear, M. J., Hope, J. and Bostock, C. Natural scrapie in a closed flock of Cheviot sheep occurs only in specific PrP genotypes. Archives of Virology 141: Bishop, S. C., Bairden, K., McKellar, Q. A., Park, M. and Stear, M. J. Genetic parameters for faecal egg count following mixed, natural predominantly Ostertagia circumcincta infection and relationships with live weight in young lambs. Animal Science 63: Stear, M. J., Reid, S. W. and Gettinby, G. The likelihood of detecting differences between groups of sheep following deliberate infection with Ostertagia circumcincta. International Journal for Parasitology 26: Stear, M. J., Park, M. and Bishop, S.C. The key components of resistance to Ostertagia circumcincta in lambs. Parasitology Today 12: Stear, M. J., Bairden, K., Bishop, S. C., Buitkamp, J., Epplen, J. T., Gostomski, D., McKellar, Q. A., Schwaiger, F-W. and Wallace, D. S. An ovine lymphocyte antigen is 8

9 associated with reduced faecal egg counts following natural, predominantly Ostertagia circumcincta infection. International Journal for Parasitology 26: Buitkamp, J., Filmether, P., Stear, M. J. and Epplen, J. T. Class I and class II Major Histocompatibility Complex alleles are associated with faecal egg counts following natural, predominantly Ostertagia circumcincta infection. Parasitology Research 82: Batra, T. R., Stear, M. J. & Macdonald, P. A. Association of class I bovine lymphocyte antigens with profitability and lifetime yields in the Holstein breed. Canadian Journal of Animal Science 76: McCririe, L., Bairden, K., Buitkamp. J., Britton, C., McKeand, J. B. and Stear, M. J. Heterogeneity in the recognition of parasite antigen by sheep infected with Ostertagia circumcincta. Parasite Immunology 19: Bishop, S. C. & Stear, M. J. Modelling responses to selection for resistance to gastrointestinal parasites in sheep. Animal Science 64: Stear, M. J., Bairden, K., Bishop, S. C., Buitkamp, J., Duncan, J. L., Gettinby, G., McKellar, Q. A., Park, M., Parkins, J. J., Reid, S. W. J., Strain, S. and Murray, M. The genetic basis of resistance to Ostertagia circumcincta in lambs. The Veterinary Journal 154: Mugambi, J. M., Bain, R. K., Wanyangu, S. W., Ihiga, M. A., Duncan, J. L., Murray, M. and Stear, M. J. Resistance of four sheep breeds to natural and subsequent artificial Haemonchus contortus infection. Veterinary Parasitology 69: Wanyangu, S. W., Mugambi, J. M., Bain, R. K., Duncan, J. L., Murray, M. and Stear, M. J. Response to artificial and subsequent natural infection with Haemonchus contortus in Red Maasai and Dorper ewes. Veterinary Parasitology 69: Stear, M.J., Bairden, K., Duncan, J. L., Holmes, P. H., McKellar, Q. A., Park, M. Strain, S., Murray, M., Bishop, S. C. & Gettinby, G. How hosts control worms. Nature 389: Nasir, L., Ndiaye, M., Seeley, C. & Stear, M. J. Sequence polymorphism in bovine major histocompatibility complex DQB loci. Animal Genetics 28, Ngure, R. M., Eckersall, P. D., Jennings, F. W., Burke, J. M., Stear, M. J., Kennedy, P. G. E. & Murray, M. Major acute phase response of haptoglobin and serum amyloid P following experimental infection of mice with Trypanosoma brucei brucei. Parasitology International 46, Scott, I., Stear, M. J., Irvine, J., Dick, A., Wallace, D. S. & McKellar, Q. A. Changes in the zymogenic cell populations of the abomasa of sheep infected with Haemonchus contortus. Parasitology 116, Wallace, D. S., Bairden, K., Duncan, J. L., Fishwick, G., Gill, M., Holmes, P. H., McKellar, Q. A., Murray, Max, Parkins, J. J. and Stear, M. J. The influence of dietary supplementation with urea on resilience and resistance to infection with Haemonchus contortus. Parasitology 116, Stear, M. J., Bairden, K., Bishop, S. C., Gettinby, G., Mckellar, Q. A. Park, M., Strain, S. & D. S. Wallace. The processes influencing the distribution of parasitic nematodes among naturally infected lambs. Parasitology 117, Stear, M. J. & Wakelin, D. Genetic Resistance to Parasitic infection. Revue Scientifique et Technique de l Office Internationale des Epizooties 17, Mwangi, E. K., Stevenson, P., Ndungu, J. M., Stear, M. J., Reid, S. W. J., Gettinby, G. & Murray, M. Studies on host resistance to tick infestations among trypanotolerant Bos indicus cattle breeds in East Africa. Annals of the New York Academy of Sciences 849,

10 76. Ellis, S. A., Staines, K. A., Stear, M. J., Hensen, E. J. & Morrison, W. I. DNA typing for BoLA class I using sequence-specific primers (PCR-SSP). European Journal of Immunogenetics 25, Stear, M. J., Strain, S. & Bishop, S. C. The mechanisms underlying resistance to nematode infection. International Journal for Parasitology 29, Strain, S. & Stear, M. J. The recognition of molecules from fourth-stage larvae of Ostertagia circumcincta by IgA from infected sheep. Parasite Immunology Stear, M. J., Bairden, K., McKellar, Q. A., Scott, I., & Strain, S. The relationship between the number and size of nematodes in the abomasum and the concentration of pepsinogen in ovine plasma. Research in Veterinary Science 67, Stear, M. J. & Bishop, S. C. The curvilinear relationship between worm length and fecundity of Ostertagia circumcincta. International Journal for Parasitology 29, Scott, I., Dick, A., Irvine, J., Stear, M. J. & McKellar, Q. A. The distribution of pepsinogen within the abomasa of cattle and sheep infected with Ostertagia spp. and sheep infected with Haemonchus contortus. Veterinary Parasitology 82, Bishop, S. C. & Stear, M. J. Genetic and epidemiological relationships between productivity and disease resistance: gastrointestinal parasite infection in growing lambs. Animal Science 69, Ellis, S. A., Holmes, E. C., Staines, K. A., Smith, K. B., Stear, M. J., McKeever, D. J., MacHugh, N. D. & Morrison, W. I. Variation in the number of expressed MHC genes in different cattle class I haplotypes. Immunogenetics Stear, M. J., Strain, S. & Bishop, S. C. How lambs control infection with Ostertagia circumcincta. Veterinary Immunology and Immunopathology 72, Doligalska, M., Moskwa, B. & Stear, M. J. Relationships among peripheral eosinophilia, eosinophil peroxidase activity, interleukin-5 concentration and faecal nematode egg count during natural, mixed gastrointestinal nematode infection. Veterinary Immunology and Immunopathology 70, Wallace, D. S., Bairden, K., Duncan, J. L., Eckersall, P. D., Fishwick, G., Holmes, P. H., McKellar, Q. A., Mitchell, S., Murray, M., Parkins, J. J. & Stear, M. J. The influence of increased feeding on the susceptibility of sheep to infection with Haemonchus contortus. Animal Science 69, Buitkamp, J., Feichtlbauer-Huber, P., Stear, M. J. Association between MHC class II alleles and resistance to the parasitic nematode Ostertagia circumcincta. Arch. Tierzucht Raadsma, H. W., McEwan, J. C., Stear, M. J. & Crawford, A. M. Genetic characterisation of protective vaccine responses in sheep using multi-valent Dichelobacter nodosus vaccines. Veterinary Immunology and Immunopathology 72, Feichtlbauer-Huber, P., Stear, M. J., Fries, R. & Buitkamp, J. Reference-strand-mediated conformation analysis of MHC alleles: a new method for high-resolution typing of the Ovar-DQB genes. Immunogenetics Stear, M. J., Mitchell, S., Strain, S., Bishop, S. C. & McKellar, Q. A. The influence of age on the variation among sheep in susceptibility to natural nematode infection. Veterinary Parasitology Bishop, S. C. & Stear, M. J. The use of a gamma-type function to assess the relationship between the number of adult Teladorsagia circumcincta and total egg output. Parasitology 121,

11 92. Stear, M. J., Bairden, K., Duncan, J. L., Eckersall, P. D., Fishwick, G., Graham, P. A., Holmes, P. H., McKellar, Q. A., Mitchell, S., Murray, M., Parkins, J. J., Wallace, D. S. The influence of relative resistance and urea-supplementation on deliberate infection with Teladorsagia circumcincta during winter. Veterinary Parasitology 94, Beuzen, N. D., Stear, M. J., Chang, K. C. Molecular markers and their use in animal breeding. The Veterinary Journal 160, Coltman, D.W., Wilson, K., Pilkington, J.G., Stear, M. J. & Pemberton, J.M. A microsatellite polymorphism in the gamma interferon gene is associated with resistance to gastrointestinal nematodes in a naturally-parasitized population of Soay sheep. Parasitology 122, Nginyi, J. M., Duncan, J. L., Mellor, D. J., Stear, M. J., Wanyangu, S. W., Bain, R. K. & Gatongi, P. M. Epidemiology of parasitic gastrointestinal nematode infections of ruminants on smallholder farms in central Kenya. Research in Veterinary Science 70, Stear, M. J., Eckersall, P. D., Graham, P. A., McKellar, Q. A., Mitchell, S. & Bishop, S. C. Fructosamine concentration and resistance to natural, predominantly Teladorsagia circumcincta infection. Parasitology 123, Bishop, S. C. & Stear, M. J. Inheritance of faecal egg counts during early lactation in Scottish Blackface ewes facing mixed, natural nematode infections. Animal Science 73, Strain, S. A. J. & Stear, M. J. The influence of protein supplementation on the immune response to Haemonchus contortus. Parasite Immunology 23, Stear, M. J., Bishop, S. C., Mallard, B. A. & Raadsma, H. The sustainability, feasibility and desirability of breeding livestock for disease resistance Research in Veterinary Science 71, Stear, M. J., Henderson, N. G., Kerr, A., McKellar, Q. A., Mitchell, S., Seeley, C. & Bishop, S. C. (2002). Eosinophilia as a marker of resistance to Teladorsagia circumcincta in Scottish Blackface lambs. Parasitology 124, Strain, S. A. J., Bishop, S. C., Henderson, N. G., Kerr, A., McKellar, Q. A., Mitchell, S. & Stear, M. J. The genetic control of IgA activity against Teladorsagia circumcincta and its association with parasite resistance in naturally infected sheep. Parasitology 124, Bai, Q., McGillivray, C., da Costa, N., Dornan, S., Evans, G., Stear, M. J. & K.-C. Chang (2003) Development of a porcine skeletal muscle cdna microarray: analysis of differential transcript expression in phenotypically distinct muscles. BMC Genomics, 4, Stear, M. J., Bishop, S. C., Henderson, N. G. and Scott, I. (2003) A Key Mechanism of Pathogenesis in Sheep Infected with the Nematode Teladorsagia circumcincta. Animal Health Research Reviews 4, Bishop, S.C. and Stear, M.J. (2003) Modeling of host genetics and resistance to infectious diseases: Understanding and controlling nematode infections. Veterinary Parasitology 115, Nginyi, J. M., Duncan, J. L., Mellor, D. J., Stear, M. J., Wanyangu, S. W., Bain, R. K. & Gatongi, P. M. (2004). Conducting on-farm trials for the control of helminthoses of sheep: Some experiences with smallholder farms in kenya. The Kenya Veterinarian Bishop, S.C. Jackson, F. Coop R.L. and Stear, M.J. (2004) Genetic parameters for resistance to nematode infections in Texel lambs and their utility in breeding programmes. Animal Science

12 107. Stear, M. J., Bairden, K., Innocent, G. T., Mitchell, S., Strain, S. and Bishop, S. C. (2004) The relationship between IgA activity against fourth-stage larvae and density-dependent effects on the number of fourth-stage larvae of Teladorsagia circumcincta in naturally infected sheep. Parasitology Sayers, G., Mitchel, S. Ryan, M., Stear M, J., Hanrahan, J. P. and Sweeney, T. (2004). Analysis of DRB1 exon 2 genotyping by STR size analysis in Suffolk and Texel sheep breeds. Irish Journal of Agricultural and Food Research Stear, M. J., Innocent, G. T. and Buitkamp, J. (2005) The evolution and maintenance of polymorphism in the major histocompatibility complex. Veterinary Immunology and Immunopathology Davies, G., Stear, M.J. and Bishop, S.C. (2005) Genetic relationships between indicator traits and nematode parasite infection levels in 6 month old lambs. Animal Science Stear, M. J., Abuargob, O., Benothman, M., Bishop, S.C., Innocent, G., Kerr, A. and Mitchell, S. (2006) Variation among faecal egg counts following natural nematode infection in Scottish Blackface lambs. Parasitology Davies, G., Stear, M. J. Benothman, M., Abuagob, O., Kerr, A., Mitchell, S. and Bishop, S. C. (2006) Quantitative trait loci associated with parasitic infection in Scottish Blackface sheep. Heredity Ellis, S. A., Bontrop, R. E., Antczak, D., Ballingall, K. Davies,C. J.Kaufman, J., Kennedy, L. J. Robinson, J., Smith, D. M., Stear, M. J., Stet, R. J. M., Waller, M. J., Walter, L., Marsh, S. G. E. (2006) ISAG/IUIS-VIC Comparative MHC Nomenclature Committee report, Immunogenetics Henderson, N. G. and Stear M.J. (2006). Eosinophil and IgA responses in sheep infected with Teladorsagia circumcincta. Veterinary Immunology and Immunopathology Ellis, S.A., Morrison, W. I., MacHugh, N. D., Birch, J., Burrells, A. and Stear, M. J. (2006) Serological and molecular diversity in the cattle MHC class I region. Immunogenetics 57: Love, S., Wyse, C. A., Stirk, A. J., Stear, M. J., Calver, P., Voute, L. C. and Mellor, D. J. (2006). Prevalence, heritability and significance of musculoskeletal conformational traits in Thoroughbred yearlings. Equine Veterinary Journal 38: Stear, M. J., Doligalska, M. Donskow-Schmelter, K. (2007) Alternatives to anthelmintics for the control of nematodes in livestock.. Parasitology Amory, J. Eckersall, P.D. Stear, M. J. (2007) Influence of rearing conditions and respiratory disease on haptoglobin levels in the pig at slaughter. Research in Veterinary Science 83: Stear, M. J., Belch, A., Donskow-Schmelter, K., Fitton, L. A., Innocent, G. T., Ishikane, C., Mateus, A., Murphy, L., Rennie, K., Smith, A. and Sayers, G. (2007). Detection of genes with moderate effects on disease resistance using ovine mhc and resistance to nematodes as an example. Veterinary Immunology and Immunopathology 120, Stear, M. J., Fitton, L. A., Innocent, G. T., Murphy, L., Rennie, K., and Matthews, L. (2007). The dynamic influence of genetic variation on the susceptibility of sheep to gastrointestinal nematode infection. Journal of the Royal Society Interface 4: Vagenas, D., White, I. M. S., Stear, M. J. and Bishop, S. C. (2007) Estimation of heritabilities and correlations between repeated faecal egg count measurements in lambs facing natural parasite challenge, using a random regression model. Journal of Agricultural Science doi: /S

13 122. Stear, M. J. (2007) Non-chemical methods of nematode control in livestock. CAB Reviews: Perspectives in Agriculture, Veterinary Science, Nutrition and Natural Resources Eckersall, P. D., Lawson, F. P., Kyle, C.E., Waterston, M., Bence, L., Stear, M. J. and Rhind, S. M. (2008) Maternal undernutrition and the ovine acute phase response to vaccination. BMC Veterinary Research 4: Denwood, M., Stear, M. J., Matthews, L., Reid, S.W.J., Toft, N., and Innocent, G.T. (2008). The distribution of the pathogenic nematode Nematodirus battus in lambs is zeroinflated. Parasitology 135 (10), DOI: /S Chylinski, C. Boag, B. Stear, M. J. and Cattadori, I. M. (2009) Effects of host characteristics and parasite intensity on growth and fecundity of Trichostrongylus retortaeformis infections in rabbits Parasitology 136: Karim Gharbi, Kevin A Glover, Louise C Stone, Elizabeth S MacDonald, Louise Matthews, Unni Grimholt and M J Stear (2009) Genetic dissection of MHC-associated susceptibility to Lepeophtheirus salmonis in Atlantic salmon. BMC Genetics 10: Stear, M. J., Boag, B., Cattadori, I. & Murphy, L. (2009). Genetic variation in resistance to mixed, predominantly Teladorsagia circumcincta nematode infections of sheep from heritabilities to gene identification. Parasite Immunology 31: Chessa, B., Pereira, F., Arnaud, F., Amorim,A., Goyache, F., Mainland, I., Kao,R., Pemberton, J., Beraldi, D., Stear, M. J., Alberto, A., Pittau, M., Ianuzzi, L., Banabazi, M.H., Kazwala, R.R., Zhang, Y.-P., Arranz, J. J., Ali, B.A., Wang, Z., Uzun, M., Dione, M. M., Olsaker, I., Holm, L.-E., Saarma, U., Ahmed, S., Marzanov, N., Eythorsdottir, E., Holland, M. J., Ajmone-Marsan, P., Bruford, M. W., Kantanen, J., Spencer, T.E., Palmerini, M. (2009) Revealing the history of sheep domestication using retrovirus integrations. Science 324: Stirling,D.S. and Stear, M.J. (2010) The direct determination of haplotypes from extended regions of genomic DNA. BMC Genomics Murphy, L., Eckersall, P.D., Bishop, S. C., Pettit, J. J. Huntley, J. F., Burchmore, R. and M. J. Stear (2010) Genetic variation among lambs in peripheral IgE activity against the larval stages of Teladorsagia circumcincta. Parasitology Benothman, M., Stear, M. J., Mitchell, S., Abuargob, O., Vijayan, R. & Kumar, S. (2010) Distribution pattern of faecal egg output and herbage larval populations of gastrointestinal nematodes in naturally infected Scottish Blackface lambs in East Scotland. Animal Science Reporter Benothman, M., Stear, M. J., Mitchell, S., Abuargob, O., Vijayan, R. & Kumar, S. (2011) Measurement of IgA activity against parasitic larvae, fecal egg count and growth rate in naturally infected sheep. Current Trends in Biotechnology and Pharmacy Diack, A.B., Gladney, C.D., Mellencamp, M.A., Stear, M.J. and Eckersall, P.D. (2011) Characterisation of plasma acute phase protein concentrations in a high health boar herd. Veterinary Immunology and Immunopathology, Singleton, D., Stear, M. J. and Matthews, L. (2011) A mechanistic model of developing immunity to Teladorsagia circumcincta infection in lambs. Parasitology Stear, M. J., Singleton, D. and Matthews, L. (2011) An evolutionary perspective on gastrointestinal nematodes of sheep. Journal of Helminthology Lee, C.Y., Munyard, K. A., Gregg, K., Wetherall, J. D., Stear, M. J. and Groth, D. (2011) The influence of MHC and immunoglobulins A and E on host resistance to gastrointestinal nematodes in sheep. Journal of Parasitology Research

14 137. Murphy L, Nalpas N., Stear M. & Cattadori I. M.,(2011) Explaining patterns of infection in free living populations using laboratory immune experiments. Parasite Immunology Ballingall, K.T., Herrmann-Hoesing, L., Robinson, J., Marsh, S.G.E., Stear, M.J. (2011) A single nomenclature and associated database for alleles at the major histocompatibility complex class II DRB1 locus of sheep. Tissue Antigens Codner, G. F., Stear, M. J., Reeve, R., Matthews, L. and Ellis, S. A. (2011) Selective forces shaping diversity in the class I region of the major histocompatibility complex in dairy cattle. Animal Genetics Stear, M. J., Nikbakht, G., Matthews, L. and Jonsson, N. (2012) Breeding for disease resistance: An introduction for the non-specialist. CAB Reviews: Perspectives in Agriculture, Veterinary Science, Nutrition and Natural Resources Hammond, J.A., Marsh, S. G. E., Robinson, J. Davies, C. J., Stear, M. J. and Ellis, S. A. (2012) Cattle MHC nomenclature: is it possible to assign sequences to discrete class I genes? Immunogenetics 64: DOI: /s Jonsson, N.N., Bock, R.E., Jorgensen, W.K., Morton, J.M., & Stear, M.J. (2012). Is endemic stability of tick-borne disease in cattle a useful concept? Trends in Parasitology, 28, Lee, C.Y., Qin, J. K. A. Munyard, K.A., Siva Subramaniam, N., Wetherall, J.D., Stear, M. J., and Groth, D.M. (2012) Conserved haplotype blocks within the sheep MHC and low SNP heterozygosity in the Class IIa subregion. Animal Genetics doi: /j x 144. Nikbakht, G., Rezaii, H., Stear, M. J., Talebi, M. and Mahmoudzadeh, H. (2012) Allelic polymorphism in the second exon of Ovar-DRB1 in fat-tailed sheep. The Veterinary Journal 192: doi: /j.tvjl Stear, M. J., Nikbakht, G., Matthews, L., Jonsson, N.N. (2013). Breeding for disease resistance in livestock and fish. Animal Science Reviews Riggio V, Matika O, Pong-Wong R, Stear MJ, Bishop SC (2013) Genome-wide association and regional heritability mapping to identify loci underlying variation in nematode resistance and body weight in Scottish Blackface lambs. Heredity Corley, S.W., Jonsson, N.N., Piper, E.K., Cutullé, C., Stear, M.J., Seddon, J.M. (2013) A mutation in the RmβAOR gene is associated with amitraz resistance in the cattle tick Rhipicephalus microplus. Proceedings of the National Academy of Sciences (USA) DOI: /pnas Irum, S., Qayyum, M., Donskow-Lysonieska, K., Zia-Ul-Huq, M., Stear, M.J. (2014) Genetic Variability in β-tubulin-1 in Benzimidazole Resistant Haemonchus contortus from Sheep in North-East Punjab, Pakistan. Pakistan Journal of Zoology 46: Darlay, R., Stear, M.J., Mason, S., Smith, J., Shaw, M.A. (2014) The heritability of abortion in pedigree Charollais flocks. Animal reproduction science 149: Omry Abuargob, Michael Stear, Staurt Mitchell, Mohamed Benothman. (2014) Effect of Lamb Gender on Susceptibility to Natural Nematode Parasite (in) Infection Scottish Black Face Lambs. Journal of Veterinary Advances 4(5) Prada de Cisneros, J.P., Matthews, L., Mair, C., Stefan, T., Stear. M.J. (2014) The transfer of IgA from mucus to plasma and the implications for diagnosis and control of nematode infections. Parasitology 141, M.J. Stear, K. Donskow-Lysoniewska, E. Sinski, M. Doligalska (2014) Annals of Parasitology Prada Jiménez de Cisneros, J., L. Matthews, C. Mair, S. Thorsten, M.J. Stear (2014) Annals of Parasitology

15 154. Prada Jiménez de Cisneros, J., Stear, M. J. Mair, C., Stefan, T., Marion, G.,and Matthews, L. (2015) An explicit immunogenetic model of gastrointestinal nematode infection in sheep. Journal of the Royal Society Interface, 11(99) Abuargob, O. and Stear, M. J. (2014) Differences between female and castrated male lambs in susceptibility to natural, predominantly Teladorsagia circumcincta infection. Veterinary Parasitology, 205(3-4): Forbes A. B., Reddick D., Stear M..J (2015) Efficacy of treatment of cattle for liver fluke at housing: influence of differences in flukicidal activity against juvenile Fasciola hepatica. The Veterinary record, 176(13): Mair, C., Matthews, L., Prada J. de Cisneros, J., Stefan,T. Stear, M.J. (2015). Multitrait indices to predict worm length and number in sheep with natural, mixed predominantly Teladorsagia circumcincta infection. Parasitology 142(6): Colette Mair, Michael Stear, Paul Johnson, Matthew Denwood, Joaquin Prada Jiménez de Cisneros, Thorsten Stefan and Louise Matthews. (2015) A Bayesian generalized random regression model for estimating heritability using overdispersed count data. Genetics Selection Evolution 47(1): 51- doi: /s Marina Atlija, Beatriz Gutíerrez-Gil, Juan-Jose Arranz, Jördis Semmer, M. J. Stear, Johannes Buitkamp (2015) Major Histocompatibility Complex Class IIB polymorphism in an ancient Spanish breed. Immunogenetics Karim Gharbi, Louise Matthews, James Bron, Ron Roberts, and Michael Stear (2015) The control of sea lice in Atlantic salmon by selective breeding. Journal of the Royal Society Interface. 12: DOI: /rsif McRae, K.M., Stear, M. J., Good, B. and Keane OM. (2015) The host immune response to gastrointestinal nematode infection in sheep. Parasite Immunology. Doi: /pim Tsai H-Y, Hamilton A, Tinch A, Guy D, Gharbi K, Stear M, Matika O, Bishop S, Houston R: Genome wide association and genomic prediction for growth traits in juvenile farmed Atlantic salmon using a high density SNP array. BMC Genomics 2015, 16(1): Siva Subramaniam N, Morgan E, Wetherall J, Stear M, Groth D. (2015). A comprehensive mapping of the structure and gene organisation in the sheep MHC class I region. BMC Genomics 2015, 16(1):810. DOI: /s MC Scheuerle, MJ Stear, A Honeder, AM Becher, K Pfister (2016) Repeatability of strongyle egg counts in naturally infected horses. Veterinary Parasitology 228: doi.org/ /j.vetpar M Yaro, KA Munyard, MJ Stear, DM Groth (2016) Combatting African Animal Trypanosomiasis (AAT) in livestock: The potential role of trypanotolerance Veterinary Parasitology 225, Hsin-Yuan Tsai, Alastair Hamilton, Alan E. Tinch, Derrick R. Guy, James E. Bron, John B. Taggart, Karim Gharbi, Michael Stear, Oswald Matika, Ricardo Pong-Wong, Steve C. Bishop and Ross D. Houston (2016) Genomic prediction of host resistance to sea lice in farmed Atlantic salmon populations Genetics Selection Evolution 48 (1), Hernández, J. N., Hernández, A., Stear, M. J., Conde-Felipe, M, Rodríguez, E., Piedrafita, D. & González, J. F. (2016) Potential role for mucosal IgA in modulating Haemonchus contortus adult worm infection in sheep. Veterinary Parasitology. 223, M. Atlija, J. M. Prada, B. Gutiérrez-Gil, F. A. Rojo-Vázquez, M. J. Stear, J. J. Arranz and M. Martínez-Valladares (2016) Implementation of an extended ZINB model in the study of low levels of natural gastrointestinal nematode infections in adult sheep. BMC Veterinary Research (2016) 12:97. DOI: /s