Guidelines for Antimicrobial treatment for treatment of confirmed infections adults
|
|
- Marshall Cummings
- 5 years ago
- Views:
Transcription
1 Guidelines for Antimicrobial treatment for treatment of confirmed infections adults This guideline gives recommendations for treatment of confirmed infections in adults for children please see the Paediatric antibiotic guidelines on the trust intranet Prescribers should be aware of the trust Antimicrobial Prescribing Policy which describes general requirements in relation to antimicrobial prescribing Prescribers should adhere to the guidelines where clinically practicable further advice can be obtained from the duty Consultant Microbiologist as needed Antibiotic duration is given as general guidance, and should not be taken as a minimum duration. Antibiotics should be reviewed on a daily basis and stopped as soon as possible. Some patients may require antibiotic courses to be lengthened if clinical response is slow or suboptimal the reason for this must be documented. The use of broad spectrum spectrum / C.difficile risk antibiotics (the five Cs) should be avoided unless there are clear clinical indications for their use ciprofloxacin (and other quinolones), cephalosporins, clindamycin, co-amoxiclav and clarithromycin (and other macrolides) Use of ultra-broad spectrum antibiotics should be restricted to recommended indications, or where recommended by a Microbiologist meropenem (and other carbapenems) and piperacillin-tazobactam MRSA INFECTION INDICATION 1ST LINE ALTERNATIVE DURATION NOTES MRSA infections (see below) The treatment of infections caused by MRSA may be complex, and cases should always be discussed with a Microbiologist. MRSA: Mild skin & soft tissue infections (bacteraemia unlikely hospital admission not required) Doxycycline or Minocycline 100mg bd or Clindamycin mg qds 7 days Isolate must be sensitive to antibiotic on laboratory testing: Tetracycline sensitive = doxycycline or minocycline 1
2 MRSA: Uncomplicated UTI MRSA: conjunctivitis (non-severe) Nitrofurantoin mg qds Chloramphenicol 0.5% eye drops 2-hourly initially, then 4- to 6-hourly as infection responds Trimethroprim 200mg bd or Doxycycline 100mg bd Gentamicin 0.3% eye drops 2-hourly initially, then 4- to 6-hourly as infection responds 7 days sensitive Until 48 hours after resolution. C. difficile INFECTION INDICATION 1ST LINE ALTERNATIVE DURATION NOTES Clostridium difficileassociated disease (CDAD) Metronidazole 400mg tds (for non-severe disease - <5 stools/day and WCC <15x10 9 /L) Vancomycin 125mg qds (for severe disease WCC >15 x 10 9 /L, rapid rise in creatinine or symptoms/signs of severe colitis) Metronidazole 500mg tds IV (only in patients who cannot tolerate oral/nasogastric medications). Erythromycin sensitive = Clindamycin sensitive Discuss with Ophthalmology if severe infection. Check sensitivity from Microbiology report 10 days -The broad-spectrum antibiotic(s) that pre-disposed to CDAD should be stopped wherever possible. -Nasogastric administration can be used if the patient cannot tolerate oral medication. -Review or stop unnecessary proton pump inhibitors (PPIs) Recurrent disease (up to 30% of patients) 1 st recurrence: Use metronidazole 400mg tds (or, only if recommended by Consultant Microbiologist, fidaxomicin 200mg bd -For more information, including management of severe disease and tapering vancomycin regimen, refer to Clostridium difficile infection Guideline for Patient Management 2
3 for 10 days) 2 nd (or subsequent) recurrence use vancomycin 125mg qds. -DO NOT use vancomycin by IV route for treatment of C.difficile infection GASTRO-INTESTINAL INFECTIONS INDICATION 1 st LINE ALTERNATIVE DURATION NOTES Salmonella enteritis Antibiotics do not reduce the duration or severity of uncomplicated infection, but do significantly increase the risk of bacterial relapse. 12 Antibiotic treatment should be considered only for those at risk of bacteraemia & its complications: neonates, elderly, immunosuppressed, cardiac valvular or mural abnormalities, prosthetic cardiac valves or vascular grafts. 16 For "at risk" patients, who require antibiotics, the regimen of choice is Ciprofloxacin 500mg 750mg bd. Please discuss with Duty Consultant Microbiologist. This is a notifiable disease Campylobacter enteritis 17 Erythromycin 250mg qds Discuss with Microbiologist 5-7 days Antibiotics should be reserved for patients with: high fever (> 38.5C) + bloody diarrhoea or more than 8 stools per day symptoms worsening at diagnosis or persisting longer than 1 week This is a notifiable disease 3
4 Bacillary dysentery (Shigella species) Ciprofloxacin 500mg bd Trimethoprim 200 mg bd 3-5 days Antibiotics should be reserved for patients with: high fever (> 38.5C) + bloody diarrhoea or more than 8 stools per day symptoms worsening at diagnosis or persisting longer than 1 week where there is an increased risk of spread, eg for patients or residents requiring hands-on care This is a notifiable disease E coli O157 Antibiotics should not be given routinely because there is evidence that this increases the risk of developing haemolyticuraemic syndrome 13 Typhoid fever Cefotaxime 1-2g tds IV Azithromycin 500mg once daily or Ciprofloxacin mg bd (only where shown to be sensitivie) 10 days (cefotaxime) 7 days (azithromycin or ciprofloxacin) Typhoid fever is a notifiable disease Note increasing incidence of ciprofloxacin resistance, especially from Indian subcontinent. Use ciprofloxacin only where isolate has been shown to be sensitive Azithromycin is alternative for oral therapy, or as additional agent if poor 4
5 Giardiasis Metronidazole 400mg tds Metronidazole 2g od (avoid 2g OD dosing regimen in pregnancy) 5 days for tds regimen 3 days for od regimen response OD dosing must not be used in pregnant patients Notifiable disease Screening and/or treatment of household contacts recommended Helicobacter pylori infection Omeprazole 20mg bd plus Clarithromycin 500mg bd plus Amoxycillin 1g bd (all ) If penicillin-allergic: Omeprazole 20mg bd plus Clarithromycin 250mg bd plus Metronidazole 400mg bd (all ) 7 days - Suspected active infection must be confirmed before Rx, e.g. by stool antigen if never treated before or by breath testing if previously treated. If Metronidazole resistance likely e.g. not from EU/North America: Tinidazole 500mg bd instead - Complicated PUD, e.g. haemorrhage, perforation, requires Omeprazole 20mg od for further 4 weeks. - Treatment failure and alternative regimens should be discussed with Consultant Gastroenterologist. TB INFECTION INDICATION 1 ST LINE ALTERNATIVE DURATION NOTES TB GENITO-URINARY INFECTION The Joint TB Committee of the British Thoracic Society recommends that all cases of TB (including extrapulmonary disease) should be managed under the direct advice of a Respiratory Physician. Tuberculosis is a notifiable disease 5
6 INDICATION 1 ST LINE ALTERNATIVE DURATION NOTES Genital Chlamydia Azithromycin 1g stat Doxycycline 100mg bd Doxycycline for 7 days. Refer to GUM for advice on further management and contact tracing. Gonorrhoea (anogenital) Ceftriaxone 500mg stat IM Plus Discuss with GUM / Microbiology Stat dose. Refer to GUM for advice on further management and contact tracing. Azithromycin 1g stat Genital herpes Aciclovir 200mg 5x daily Not applicable. 5 days Refer to GUM for advice on further management and contact tracing. Syphilis A positive Syphilis antibody ELISA (or TPHA FTA) indicates previous treponemal infection, which, in combination with a positive IgM, indicates active disease. Previous untreated infection and current active infection require treatment; such cases Refer to GUM for advice on management and contact tracing. 6
7 should be managed by GUM. VIRAL INFECTION INDICATION 1 ST LINE ALTERNATIVE DURATION NOTES Chickenpox/zoster - Uncomplicated Aciclovir 800mg x 5 daily Not applicable. 7 days. Only effective if started < 24 hours of onset of rash Chickenpox/zoster - Complicated Aciclovir 10mg/kg tds IV (usually 750mg tds IV) Not applicable. 10 days for pneumonitis and encephalitis; otherwise 5 days. Complications include: persistent fever and/or appearance of new vesicles after 5 days of the onset pneumonitis encephalitis Herpes simplex encephalitis Aciclovir 10mg/kg tds IV (usually 750mg tds IV) Not applicable. At least 10 days, possibly days. PARASITIC INFECTION INDICATION 1 ST LINE ALTERNATIVE DURATION NOTES Falciparum malaria Uncomplicated malaria (see notes) Quinine 600mg (of quinine salt*) tds plus Doxycycline 200mg od Discuss all cases of complicated malaria with Infectious Diseases Physician. Quinine plus Doxycycline and/or Clindamycin for 7 days Ensure adequate hydration with IV acyclovir risk of renal toxicity For encephalitis need to give all treatment IV Seriously ill patients require IV Quinine, and their management must be discussed with a Infectious Diseases Physician. 7
8 or Clindamycin 450mg tds Complicated malaria or if patient vomiting: Quinine 20mg/kg (max 1.4g) IV loading dose of quinine salt over 4h No loading dose if patient taking quinine or mefloquine already during the previous 12 hours).t Then 10mg/kg** (max 700mg) infused over 4 hours every 8 hours plus Doxycycline 200mg od or Clindamycin 450mg tds IV/ When stable and able to swallow, switch to oral quinine 600mg tds, plus doxycycline or clindamycin as above. Hospital of Tropical Diseases UCL: tel and ask for Duty Doctor for Tropical Medicine Complicated malaria = one or more of: Impaired consciousness or seizures Parasite count 2% Hb 8g/dL Spontaneous bleeding/dic Haemoglobinuria (without G6PD deficiency) Renal impairment or ph <7.3 Pulmonary oedema or ARDS Shock ( may be due to Gram negative sepsis) Malaria is a notifiable disease notify to the CCDC at the local HPU * Valid for quinine hydrochloride, dihydrochloride and sulphate. Not valid for quinine bisulphate which contains smaller amount of quinine. * *Maintenance dose should be reduced to 5-7mg/kg of quinine salt in patients with severe renal impairment, severe hepatic impairment, or 8
9 Vivax malaria Chloroquine 625 mg of base stat then 310 mg of base after 6-8 hours Not applicable. Primaquine for 14 days if parenteral treatment is required for more than 48 hours. *Patients should be tested for G6PD deficiency before commencing primaquine then 310 mg of base od for 2 days followed by: Primaquine* 30mg od 9
Infection Comments First Line Agents Penicillin Allergy History of multiresistant. line treatment: persist for >7 days they may be
Gastrointestinal Infections Infection Comments First Line Agents Penicillin Allergy History of multiresistant Campylobacter Antibiotics not recommended. Erythromycin 250mg PO 6 Alternative to first N/A
More informationGUIDELINES FOR THE MANAGEMENT OF COMMUNITY-ACQUIRED PNEUMONIA IN ADULTS
Version 3.1 GUIDELINES FOR THE MANAGEMENT OF COMMUNITY-ACQUIRED PNEUMONIA IN ADULTS Date ratified June 2008 Updated March 2009 Review date June 2010 Ratified by Authors Consultation Evidence base Changes
More informationWomen s Antimicrobial Guidelines Summary
Women s Antimicrobial Guidelines Summary 1. Introduction and Who Guideline applies to This guideline has been developed to deliver safe and appropriate empirical use of antibiotics for patients at University
More informationINFECTIONS IN CHILDREN-ANTIMICROBIAL MANAGEMENT
INFECTIONS IN CHILDREN-ANTIMICROBIAL MANAGEMENT Name & Title Of Authors: Dr M Milupi, Consultant Microbiologist Dr N Rao,Consultant Paediatrician Dr V Desai Consultant Paediatrician Date Revised: DEC 2015
More informationGuidelines for the Initiation of Empirical Antibiotic therapy in Respiratory Disease (Adults)
Guidelines for the Initiation of Empirical Antibiotic therapy in Respiratory Disease (Adults) Community Acquired Pneumonia Community Acquired Pneumonia 1) Is it pneumonia? ie new symptoms and signs of
More informationINFECTIONS IN CHILDREN-ANTIMICROBIAL MANAGEMENT
INFECTIONS IN CHILDREN-ANTIMICROBIAL MANAGEMENT Name & Title Of Authors: Dr M Milupi, Consultant Microbiologist Dr N Rao,Consultant Paediatrician Dr V Desai Consultant Paediatrician Date Revised: APRIL
More informationRational management of community acquired infections
Rational management of community acquired infections Dr Tanu Singhal MD, MSc Consultant Pediatrics and Infectious Disease Kokilaben Dhirubhai Ambani Hospital, Mumbai Why is rational management needed?
More informationDRAFT DRAFT. Paediatric Antibiotic Prescribing Guideline. May
Paediatric Antibiotic Prescribing Guideline www.oxfdahsn.g/children Magdalen Centre Nth, 1 Robert Robinson Avenue, Oxfd Science Park, OX4 4GA, United Kingdom t: +44(0) 1865 784944 e: info@oxfdahsn.g Follow
More informationyour hospitals, your health, our priority PARC (Policy Approval and Ratification Committee) STANDARD OPERATING PROCEDURE:
STANDARD OPERATING PROCEDURE: TRUST ANTIBIOTIC TREATMENT SOP SOP NO: TW10/136 SOP 1 VERSION NO: VERSION 6.1 (JANUARY 2013) APPROVING COMMITTEE: INFECTION PREVENTION AND CONTROL COMMITTEE DATE THIS VERSION
More informationIntro Who should read this document 2 Key practice points 2 Background 2
Antibiotic Guidelines: Obstetric Anti-Infective Prescribing Guidelines Classification: Clinical Guideline Lead Author: Antibiotic Steering Committee Additional author(s): Kelly Alexander / Frances Garraghan
More informationGuidelines for the Initiation of Empirical Antibiotic therapy in Respiratory Disease (Adults)
Guidelines for the Initiation of Empirical Antibiotic therapy in Respiratory Disease (Adults) Community Acquired Community Acquired 1) Is it pneumonia? ie new symptoms and signs of a lower respiratory
More informationAntimicrobial Prescribing Advice for patients with Clostridium difficile Associated Diarrhoea
For use in: By: For: Antimicrobial Prescribing Advice for patients with Clostridium difficile Division responsible for document: Key words: Names of document authors: Job titles of document authors: Name
More informationAntimicrobial Update. Alison MacDonald Area Antimicrobial Pharmacist NHS Highland April 2018
Antimicrobial Update Alison MacDonald Area Antimicrobial Pharmacist NHS Highland alisonc.macdonald@nhs.net April 2018 Starter Questions Setting the scene... What if antibiotics were no longer effective?
More informationGuidelines for the Empirical Treatment of Sepsis in Adults (excluding Neutropenic Sepsis)
Guidelines for the Empirical Treatment of Sepsis in Adults (excluding Neutropenic Sepsis) Full Title of Guideline: Author (include email and role): Division & Speciality: Scope (Target audience, state
More informationPneumonia Antibiotic Guidance for Adults PAGL Inclusion Approved at January 2017 PGC
Pneumonia Antibiotic Guidance for Adults PAGL Inclusion Approved at January 2017 PGC APPROVED BY: Policy and Guidelines Committee TRUST REFERENCE: B9/2009 AWP Ref: AWP61 Date (approved): July 2008 REVIEW
More informationPerichondritis: Source: UpToDate Ciprofloxacin 10 mg/kg/dose PO (max 500 mg/dose) BID Inpatient: Ceftazidime 50 mg/kg/dose q8 hours IV
Empiric Antibiotics for Pediatric Infections Seen in ED NOTE: Choice of empiric antibiotic therapy must take into account local pathogen frequency and resistance patterns, individual patient characteristics,
More informationInteractive session: adapting to antibiogram. Thong Phe Heng Vengchhun Felix Leclerc Erika Vlieghe
Interactive session: adapting to antibiogram Thong Phe Heng Vengchhun Felix Leclerc Erika Vlieghe Case 1 63 y old woman Dx: urosepsis? After 2 d: intermediate result: Gram-negative bacilli Empiric antibiotic
More informationSepticaemia Definitions 1
Septicaemia Definitions 1 Term Definition Bacteraemia Systemic Inflammatory response (SIRS) Sepsis Bacteria that can be cultured from the blood stream The systemic response to a wide range of stresses.
More informationPIPERACILLIN- TAZOBACTAM INJECTION - SUPPLY PROBLEMS
PIPERACILLIN- TAZOBACTAM INJECTION - SUPPLY PROBLEMS The current supply of piperacillin- tazobactam should be reserved f Microbiology / Infectious Diseases approval and f neutropenic sepsis, severe sepsis
More informationAntibiotic Prophylaxis in Spinal Surgery Antibiotic Guidelines. Contents
Antibiotic Prophylaxis in Spinal Antibiotic Guidelines Classification: Clinical Guideline Lead Author: Antibiotic Steering Committee Additional author(s): Authors Division: DCSS & Tertiary Medicine Unique
More informationThese recommendations were approved for use by the Pharmaceutical and Therapeutics Committee, RCWMCH on 1 February 2017.
Antibiotic regimens for suspected hospital-acquired infection (HAI) outside the Paediatric Intensive Care Unit at Red Cross War Memorial Children s Hospital (RCWMCH) Lead author: Brian Eley Contributing
More informationSURGICAL ANTIBIOTIC PROPHYLAXIS GUIDELINES WITHIN ORTHOPAEDIC SURGERY FOR ADULT PATIENTS
SURGICAL ANTIBIOTIC PROPHYLAXIS GUIDELINES WITHIN ORTHOPAEDIC SURGERY FOR ADULT PATIENTS Full Title of Guideline: Author (include email and role): Division & Speciality: Scope (Target audience, state if
More informationAntibiotic Usage Guidelines in Hospital
SUPPLEMENT TO JAPI december VOL. 58 51 Antibiotic Usage Guidelines in Hospital Camilla Rodrigues * Use of surveillance data information of Hospital antibiotic policy guidelines from Hinduja Hospital. The
More informationVolume 1; Number 7 November 2007
Volume 1; Number 7 November 2007 CONTENTS Page 1 Page 3 Guidance on the Use of Antibacterial Drugs in Lincolnshire Primary Care: Winter 2007/8 NICE Clinical Guideline 54: Urinary Tract Infection in Children
More informationAntibiotic Stewardship Program (ASP) CHRISTUS SETX
Antibiotic Stewardship Program (ASP) CHRISTUS SETX Program Goals I. Judicious use of antibiotics Decrease use of broad spectrum antibiotics and deescalate use based on clinical symptoms Therapeutic duplication:
More informationAntimicrobial Update Stewardship in Primary Care. Clare Colligan Antimicrobial Pharmacist NHS Forth Valley
Antimicrobial Update Stewardship in Primary Care Clare Colligan Antimicrobial Pharmacist NHS Forth Valley Setting the Scene! Consequences of Antibiotic Use? Resistance For an individual patient with
More informationANTIBIOTIC PRESCRIBING POLICY FOR DIABETIC FOOT DISEASE IN SECONDARY CARE
ANTIBIOTIC PRESCRIBING POLICY FOR DIABETIC FOOT DISEASE IN SECONDARY CARE Version 1.0 Date ratified June 2009 Review date June 2011 Ratified by Authors Consultation Nottingham Antibiotic Guidelines Committee
More informationGASTRO-INTESTINAL TRACT INFECTIONS - ANTIMICROBIAL MANAGEMENT
GASTRO-INTESTINAL TRACT INFECTIONS - ANTIMICROBIAL MANAGEMENT DRAFT AS CURRENTLY OUT FOR CONSULTATION BUT CAN BE UTILISED IN PRESENT FORMAT Name & Title Of Author: Date Revised: Approved by Committee/Group:
More informationNational Antimicrobial Prescribing Survey
Indication documented Surgical prophylaxis >24 hrs Allergy mismatch Microbiology mismatch Incorrect route Incorrect dose/frequency Incorrect duration Therapeutic Guidelines Local guidelines * Non-compliant
More informationVolume. December Infection. Notes. length of. cases as 90% 1 week. tonsillitis. First Line. sore throat / daily for 5 days. quinsy >4000.
Volume 8; Number 22 LINCOLNSHIRE GUIDELINES FOR THE TREATMENT OF COMMONLYY OCCURRING INFECTIONS IN PRIMARY CARE: WINTER 2014/15 In this issue of the PACE Bulletin we present an update of our Guidelines
More informationAntibiotic Updates: Part II
Antibiotic Updates: Part II Fredrick M. Abrahamian, DO, FACEP, FIDSA Health Sciences Clinical Professor of Emergency Medicine David Geffen School of Medicine at UCLA Los Angeles, California Financial Disclosures
More informationThey are updated regularly as new NICE guidance is published. To view the latest version of this NICE Pathway see:
Helicobacter pylori testing and eradication in adults bring together everything NICE says on a topic in an interactive flowchart. are interactive and designed to be used online. They are updated regularly
More informationAntibiotics Guidelines: Gastrointestinal Infections
Antibiotics Guidelines: Gastrointestinal Infections Classification: Clinical Guideline Lead Author: Antibiotic Steering Committee Additional author(s): Authors Division: DCSS & Tertiary Medicine Unique
More informationSuggested treatment. Inj Crystalline Penicillin 50,000U/Kg i.v. 4-6hrly (if child cannot swallow) 40mg/Kg/dose BID x 10days
GUIDELINES FOR TREATMENT OF INFECTIONS IN CHILDREN A. RESPIRATORY TRACT INFECTIONS UPPER RESPIRATORY TRACT INFECTIONS Infection/Condition/likely organism Suggested treatment Preferred Alternative Acute
More informationDuke University Hospital Guideline for Empiric Inpatient Treatment of Cancer- Related Neutropenic Fever in Adult Patients
Duke University Hospital Guideline for Empiric Inpatient Treatment of Cancer- Related Neutropenic Fever in Adult Patients PURPOSE Fever among neutropenic patients is common and a significant cause of morbidity
More informationTreatment of Helicobacter pylori infection in adults
APPROPRIATENESS OF CARE Treatment of Helicobacter pylori infection in adults May 2017 Helicobacter pylori (H. pylori) infection plays a major role in the development of gastroduodenal ulcer and gastric
More informationUpdated recommended treatment regimens for gonococcal infections and associated conditions United States, April 2007
Updated recommended treatment regimens for gonococcal infections and associated conditions United States, April 2007 1 Ongoing data from CDC 's Gonococcal Isolate Surveillance Project (GISP), including
More informationNHS The NHS in Rotherham ANTIMICROBIAL SUMMARY PROTOCOL FOR THE MANAGEMENT OF INFECTION IN PRIMARY CARE Next review due December 2019
NHS ANTIMICROBIAL SUMMARY PROTOCOL F THE MANAGEMENT OF INFECTION IN PRIMARY CARE 2017-2019 Next review due December 2019 To be used in conjunction with the detailed Antimicrobial Protocol for the Management
More informationAcute Pyelonephritis POAC Guideline
Acute Pyelonephritis POAC Guideline Refer full regional pathway http://aucklandregion.healthpathways.org.nz/33444 EXCLUSION CRITERIA: COMPLICATED PYELONEPHRITIS Discuss with relevant specialist for advice
More informationAntibiotic Guidelines
Antibiotic Guidelines Antibiotics were first discovered in the middle of the 20 th century and have since saved millions of lives and practically eradicated previously fatal conditions such as tuberculosis
More informationCommunity Antibiotic Guidelines For Common Infections in Adults
Coventry & Warwickshire Area Prescribing Committee Clinical Guideline CG005 Community Antibiotic Guidelines For Common Infections in Adults Coventry and Warwickshire Microbiology Appendix A Guideline developed
More informationVolume 2; Number 16 October 2008
Volume 2; Number 16 October 2008 What s new this month NHS Lincolnshire have launched a public information campaign designed to raise public awareness of the risks associated with the inappropriate use
More informationTrust Guideline for the Management of: Antibiotic Prophylaxis in adults undergoing procedures in Interventional Radiology
Antibiotic Prophylaxis in adults undergoing procedures in Interventional Radiology A Clinical Guideline For use in: By: For: Division responsible for document: Key words: Interventional Radiology Prescribers
More information1. The preferred treatment option for an initial UTI episode in a 22-year-old female patient
1 Chapter 79, Self-Assessment Questions 1. The preferred treatment option for an initial UTI episode in a 22-year-old female patient with normal renal function is: A. Trimethoprim-sulfamethoxazole B. Cefuroxime
More information21 st Expert Committee on Selection and Use of Essential Medicines Peer Review Report Antibiotics Review
(1) Have all important studies/evidence of which you are aware been included in the application? Yes No Please provide brief comments on any relevant studies that have not been included: (2) For each of
More informationAminoglycosides. Spectrum includes many aerobic Gram-negative and some Gram-positive bacteria.
Aminoglycosides The only bactericidal protein synthesis inhibitors. They bind to the ribosomal 30S subunit. Inhibit initiation of peptide synthesis and cause misreading of the genetic code. Streptomycin
More informationmoxifloxacin intravenous, 400mg/250mL, solution for infusion (Avelox ) SMC No. (650/10) Bayer Schering
moxifloxacin intravenous, 400mg/250mL, solution for infusion (Avelox ) SMC No. (650/10) Bayer Schering 05 November 2010 The Scottish Medicines Consortium (SMC) has completed its assessment of the above
More informationWho should read this document 2. Key practice points 2. Background/ Scope/ Definitions 2. What is new in this version 3. Policy/Procedure/Guideline 3
Antibiotic Prophylaxis in Cranial Neurosurgery Antibiotic Classification: Clinical Guideline Lead Author: Antibiotic Steering Committee Additional author(s): as above Authors Division: DCSS & Tertiary
More informationAdult Antibiotic Guidelines. Secondary Care
Adult Antibiotic Guidelines Secondary Care Please note: The Antibiotic Prophylaxis Guideline full document is available on the intranet N.B. Staff should be discouraged from printing this document. This
More informationMANAGEMENT OF PELVIC INFLAMMATORY DISEASE
GYNAECOLOGY SERVICES NORTH CUMBRIA MANAGEMENT OF PELVIC INFLAMMATORY DISEASE Author/Contact DOCUMENT CONTROL Lufti Shamsuddin, ST4 Obs & Gynae Trainee / Nalini Munjuluri, Consultant Gynaecology Tel: 01228
More informationPharmaceutical issues relating to STI s. June Minton Lead HIV/GUM & Infectious Diseases Pharmacist University College London Hospitals NHS Trust
Pharmaceutical issues relating to STI s June Minton Lead HIV/GUM & Infectious Diseases Pharmacist University College London Hospitals NHS Trust Objectives Treatment options for syphilis, LGV, TV, gonorrhoea
More informationMicrobiology : antimicrobial drugs. Sheet 11. Ali abualhija
Microbiology : antimicrobial drugs Sheet 11 Ali abualhija return to our topic antimicrobial drugs, we have finished major group of antimicrobial drugs which associated with inhibition of protein synthesis
More informationMEDICAL SPECIALITIES A.CARDIOVASCULAR INFECTIONS
MEDICAL SPECIALITIES A.CARDIOVASCULAR INFECTIONS Infection/Condition/lik ely organism Infective endocarditis native valve/due to Penicillin- Susceptible Streptococcus Viridans/S.bovis Suggested treatment
More informationIntroduction to Chemotherapeutic Agents. Munir Gharaibeh MD, PhD, MHPE School of Medicine, The university of Jordan November 2018
Introduction to Chemotherapeutic Agents Munir Gharaibeh MD, PhD, MHPE School of Medicine, The university of Jordan November 2018 Antimicrobial Agents Substances that kill bacteria without harming the host.
More informationChildrens Hospital Antibiogram for 2012 (Based on data from 2011)
Childrens Hospital Antibiogram for 2012 (Based on data from 2011) Prepared by: Department of Clinical Microbiology, Health Sciences Centre For further information contact: Andrew Walkty, MD, FRCPC Medical
More informationTable 1. Commonly encountered or important organisms and their usual antimicrobial susceptibilities.
Table 1. Commonly encountered or important organisms and their usual antimicrobial susceptibilities. Gram-positive cocci: Staphylococcus aureus: *Resistance to penicillin is almost universal. Resistance
More informationManagement of Malaria in Children : Update 2008
G U I D E L I N E S Management of Malaria in Children : Update 2008 INFECTIOUS DISEASES CHAPTER, INDIAN ACADEMY OF PEDIATRICS ABSTRACT Justification: The first guideline on diagnosis and management of
More informationConsiderations in antimicrobial prescribing Perspective: drug resistance
Considerations in antimicrobial prescribing Perspective: drug resistance Hasan MM When one compares the challenges clinicians faced a decade ago in prescribing antimicrobial agents with those of today,
More informationPrepared: August Review: July Common Infections. A Medicines Optimisation Antibiotic Prescribing Guide.
Prepared: August 2013 Review: July 2014 Common Infections. A Medicines Optimisation Antibiotic Prescribing Guide. Contents Page: Page No Why do we want to review antibiotics? 2 What do NICE say? 3 Acute
More informationGUIDELINES FOR IV TO ORAL SWITCH FOR ANTIBITOICS
Index No: MMG51t GUIDELINES FOR IV TO ORAL SWITCH FOR ANTIBITOICS Version: 1.0 Date ratified: June 2017 Ratified by: (Name of Committee) Director Lead (Trust-wide policies) Associate Medical Director (local
More informationAuthor s: Clinical Standards Group and Effectiveness Sub-Board
Trust Antibiotic Policy for the Management of Common Infections in Accident and Emergency and Cromer Minor Injuries Unit (Paediatrics) Accident and Emergency, Norfolk and Norwich and For Use in: Cromer
More informationClinical Practice Standard
Clinical Practice Standard 1-20-6-1-010 TITLE: INTRAVENOUS TO ORAL CONVERSION FOR ANTIMICROBIALS A printed copy of this document may not reflect the current, electronic version on OurNH. APPLICABILITY:
More informationUTI Dr S Mathijs Department of Pharmacology
UTI Dr S Mathijs Department of Pharmacology Introduction Responsible for > 7 million consultations annually 15% of all antibiotic prescriptions 40% of all hospital acquired infections Significant burden
More informationSuggestions for appropriate agents to include in routine antimicrobial susceptibility testing
Suggestions for appropriate agents to include in routine antimicrobial susceptibility testing These suggestions are intended to indicate minimum sets of agents to test routinely in a diagnostic laboratory
More informationDr Eleri Davies. Consultant Microbiologist and Infection Control Doctor, Public Health Wales NHS Trust
Dr Eleri Davies Consultant Microbiologist and Infection Control Doctor, Public Health Wales NHS Trust Antimicrobial stewardship What is it? Why is it important? Treatment and management of catheter-associated
More informationReferences and supporting documents 5 Roles and responsibilities 5
Antibiotic Therapy for Patients with Antibody Deficiency Guidelines for Classification: guidelines Lead Author: Dr Archana Herwadkar, Paul Chadwick Additional author(s): Dr Hana Alachkar Authors Division:
More informationClinical Guideline. District Infectious Diseases Management. Go to Guideline. District Infectious Diseases Management CG 18_24
Clinical Guideline District Infectious Diseases Management Sites where Clinical Guideline applies All facilities This Clinical Guideline applies to: 1. Adults Yes 2. Children up to 16 years Yes 3. Neonates
More informationAdult Empirical Antibiotic Pocketguide (Apr 2010)
Adult Empirical Antibiotic Pocketguide (Apr 2010) Please refer to full guidance for details. All doses are for NON-PREGNANT ADULTS with NMAL renal and hepatic function. For advice on pregnant patients
More informationWho should read this document 2. Key practice points 2. Background/ Scope/ Definitions 2. What is new in this version 2. Policy/Procedure/Guideline 4
Antibiotic Guidelines Antibiotic Prophylaxis in Urology Classification: Clinical Guideline Lead Author: Antibiotic Steering Committee Additional author(s): Authors Division: DCSS & Tertiary Medicine Unique
More informationAntibiotic Guideline: Empirical Treatment of Bone and Joint Infection in Adults
Antibiotic Guideline: Empirical Treatment of Bone and Joint Infection in Adults Document type: Prescribing guideline Version: 5.0 Author (name and designation) Samim Patel, Antimicrobial Lead Pharmacist
More informationWho should read this document 2. Key practice points 2. Background/ Scope/ Definitions 2. What is new in this version 2. Policy/Procedure/Guideline 4
Antibiotic Guidelines Antibiotic Prophylaxis in Urology Classification: Clinical Guideline Lead Author: Antibiotic Steering Committee Additional author(s): Authors Division: DCSS & Tertiary Medicine Unique
More informationOBSTETRICS & GYNAECOLOGY. Penicillin G 5 million units IV ; followed by 2.5 million units 4hourly upto delivery
OBSTETRICS & GYNAECOLOGY A.OBSTETRICS Infection/Condition/likely organism Intrapartum Group B Streptococcal (GBS) infection; positive mothers Suggested treatment Preferred Penicillin G 5 million units
More informationMANAGEMENT OF INFECTION GUIDANCE FOR PRIMARY CARE PRESCRIBERS IN NORTHAMPTONSHIRE
MANAGEMENT OF INFECTION GUIDANCE FOR PRIMARY CARE PRESCRIBERS IN NORTHAMPTONSHIRE Aims to provide a simple, empirical approach to the treatment of common infections to promote the safe, effective and economic
More informationPrinciples of Antimicrobial therapy
Principles of Antimicrobial therapy Laith Mohammed Abbas Al-Huseini M.B.Ch.B., M.Sc, M.Res, Ph.D Department of Pharmacology and Therapeutics Antimicrobial agents are chemical substances that can kill or
More informationJoint Trust Guideline for the Antibiotic Management of Diabetes Related Foot Infections in Adults
Joint Trust Guideline for the Antibiotic Management of Diabetes Related Foot Infections in Adults A clinical guideline recommended For use in: Clinical areas treating patients with diabetes related foot
More information2015 Antibiotic Susceptibility Report
Citrobacter freundii Enterobacter aerogenes Enterobacter cloacae Escherichia coli Haemophilus influenzenza Klebsiella oxytoca Klebsiella pneumoniae Proteus mirabilis Pseudomonas aeruginosa Serratia marcescens
More informationCommunity-Associated C. difficile Infection: Think Outside the Hospital. Maria Bye, MPH Epidemiologist May 1, 2018
Community-Associated C. difficile Infection: Think Outside the Hospital Maria Bye, MPH Epidemiologist Maria.Bye@state.mn.us 651-201-4085 May 1, 2018 Clostridium difficile Clostridium difficile Clostridium
More informationEAGAR Importance Rating and Summary of Antibiotic Uses in Humans in Australia
EAGAR Importance Rating and Summary of Antibiotic Uses in Humans in Australia Background The Expert Advisory Group on Antimicrobial Resistance of the NH&MRC provides advice to Australian governments and
More informationThis letter authorises the extended use of the following guidance until 1st December 2018:
NHS Grampian Westholme Woodend Hospital Queens Road ABERDEEN AB15 6LS NHS Grampian Date 29m May 2018 Our Ref FAJIVOST /MGPG/May 18 Enquiries to Frances Adamson Extension 56689 Direct Line 01224 556689
More informationObjectives. Review basic categories of intra-abdominal infection and their respective treatments. Community acquired intra-abdominal infection
Objectives Review basic categories of intra-abdominal infection and their respective treatments Community acquired intra-abdominal infection Mild/Moderate Severe Acute biliary tract infections Nosocomial
More information2016 Antibiotic Susceptibility Report
Fairview Northland Medical Center and Elk River, Milaca, Princeton and Zimmerman Clinics 2016 Antibiotic Susceptibility Report GRAM-NEGATIVE ORGANISMS 2016 Gram-Negative Non-Urine The number of isolates
More informationMedicinal Chemistry 561P. 2 st hour Examination. May 6, 2013 NAME: KEY. Good Luck!
Medicinal Chemistry 561P 2 st hour Examination May 6, 2013 NAME: KEY Good Luck! 2 MDCH 561P Exam 2 May 6, 2013 Name: KEY Grade: Fill in your scantron with the best choice for the questions below: 1. Which
More informationPaediatric Empirical Antimicrobial Guidance for Infections in Hospital
Paediatric Empirical Antimicrobial Guidance for Infections in Hospital This guidance is for empirical treatment. Alternative antibiotics may be required if specific pathogens are identified or there is
More informationApproach to pediatric Antibiotics
Approach to pediatric Antibiotics Gassem Gohal FAAP FRCPC Assistant professor of Pediatrics objectives To be familiar with common pediatric antibiotics o Classification o Action o Adverse effect To discus
More informationOverview of C. difficile infections. Kurt B. Stevenson, MD MPH Professor Division of Infectious Diseases
Overview of C. difficile infections Kurt B. Stevenson, MD MPH Professor Division of Infectious Diseases Conflicts of Interest I have no financial conflicts of interest related to this topic and presentation.
More informationAntibiotic Prophylaxis in General Surgery Antibiotic Guidelines. Contents
Antibiotic Prophylaxis in General Surgery Antibiotic Guidelines Classification: Clinical Guideline Lead Author: Antibiotic Steering Committee Authors Division: CSS&TM Unique ID: 144TD(C)25(F3) Issue number:
More informationAntibiotic Updates: Part I
Antibiotic Updates: Part I Fredrick M. Abrahamian, DO, FACEP, FIDSA Health Sciences Clinical Professor of Emergency Medicine David Geffen School of Medicine at UCLA Los Angeles, California Financial Disclosures
More informationEMPIRICAL ANTIBIOTIC GUIDELINES FOR THE MANAGEMENT OF COMMON INFECTIONS IN ADULT INPATIENTS
EMPIRICAL ANTIBIOTIC GUIDELINES FOR THE MANAGEMENT OF COMMON INFECTIONS IN ADULT INPATIENTS Useful contacts: Consultant Clinical Microbiologist via switchboard Antimicrobial Pharmacist Bleep 294 Medicines
More informationPVL Staph aureusjust a skin/soft tissue problem? Layla Mohammadi Lead Pharmacist, Antimicrobials Lewisham Healthcare NHS Trust
PVL Staph aureusjust a skin/soft tissue problem? Layla Mohammadi Lead Pharmacist, Antimicrobials Lewisham Healthcare NHS Trust Neonatal Case History Neonate born at 26 +2 gestation Spontaneous onset of
More informationجداول میکروارگانیسم های بیماریزای اولویت دار و آنتی بیوتیک های تعیین شده برای آزمایش تعیین حساسیت ضد میکروبی در برنامه مهار مقاومت میکروبی
جداول میکروارگانیسم های بیماریزای اولویت دار و آنتی بیوتیک های تعیین شده برای آزمایش تعیین حساسیت ضد میکروبی در برنامه مهار مقاومت میکروبی ویرایش دوم بر اساس ed., 2017 CLSI M100 27 th تابستان ۶۹۳۱ تهیه
More informationFOLLOWING BUNDLE ADMINISTERED WITHIN ONE HOUR.
Patient label DATE and TIME: 1 REVIEW BY Emergency Department SENIOR REGISTRAR (ED BLEEP 5999) +/-Leave Proforma 2 FOLLOWING BUNDLE ADMINISTERED WITHIN ONE HOUR. Bloods for FBC, U+E, CRP, LFT s, Clotting
More information9/30/2016. Dr. Janell Mayer, Pharm.D., CGP, BCPS Dr. Lindsey Votaw, Pharm.D., CGP, BCPS
Dr. Janell Mayer, Pharm.D., CGP, BCPS Dr. Lindsey Votaw, Pharm.D., CGP, BCPS 1 2 Untoward Effects of Antibiotics Antibiotic resistance Adverse drug events (ADEs) Hypersensitivity/allergy Drug side effects
More information* gender factor (male=1, female=0.85)
Usual Doses of Antimicrobials Typically Not Requiring Renal Adjustment Azithromycin 250 500 mg Q24 *Amphotericin B 1 3-5 mg/kg Q24 Clindamycin 600 900 mg Q8 Liposomal (Ambisome ) Doxycycline 100 mg Q12
More informationAntibiotic Guidelines
CLINICAL GUIDELINE For use in (clinical areas): For use by (staff groups): For use for (patients): Document owner: Status: All clinical areas All clinicians For use for all patients Consultant Microbiologists
More informationMercy Medical Center Des Moines, Iowa Department of Pathology. Microbiology Department Antibiotic Susceptibility January December 2016
Mercy Medical Center Des Moines, Iowa Department of Pathology Microbiology Department Antibiotic Susceptibility January December 2016 These statistics are intended solely as a GUIDE to choosing appropriate
More informationThe Rational Use of Antibiotics
The Rational Use of Antibiotics CONTINUING MEDICAL EDUCATION V K E Lim MBBS, FRCPath, Department of Medical Microbiology and Immunology; Faculty of Medicine Universiti Kebangsaan Malaysia, P 0 Box 12418,
More informationAntibiotic Formulary 2015/16
ww Great Yarmouth and Waveney area Primary Care, Community Services and Out of Hours Antibiotic Formulary 2015/16 Revision date: Autumn 2016 Primary Care, Community Services and Out of Hours - Antibiotics
More informationTreatment of peritonitis in patients receiving peritoneal dialysis Antibiotic Guidelines. Contents
Treatment of peritonitis in patients receiving Antibiotic Guidelines Classification: Clinical Guideline Lead Author: Jude Allen (Pharmacist) Additional author(s): Dr David Lewis, Dr Dimitrios Poulikakos,
More information11/10/2016. Skin and Soft Tissue Infections. Disclosures. Educational Need/Practice Gap. Objectives. Case #1
Disclosures Selecting Antimicrobials for Common Infections in Children FMR-Contemporary Pediatrics 11/2016 Sean McTigue, MD Assistant Professor of Pediatrics, Pediatric Infectious Diseases Medical Director
More informationAntimicrobial Policy for Adults
The Rotherham NHS Foundation Trust Barnsley Hospital NHS Foundation Trust Antimicrobial Policy for Adults Beta-lactams Penicillins Cephalosporins Amoxicillin Cefalexin Benzylpenicillin Cefotaxime Co-amoxiclav
More information