Medical Parasitology PAR 311 Basic Information Program Title Bachelor of Medicine and Surgery; MB,BCh Department Offering the Course Academic Year / Level Date of Specification Approval Total Teaching Hours Medical Parasitology Third year October, 2011 Total: 112 hours Lecture: 54 hours Interactive e- sessions: 12 hours Practical: 46 hours Allocated Marks 150 Marks Allocated Duration September to May (one academic year) Course Director Teaching Staff Prof. Mahmoud El Sebaie Head of Department Professors:30 Assistant Professors: 7 Lecturers : 11 Assistant lecturers: 5 Demonstrators: 8 1 of 12 2011-2012
Professional Information 1- Overall Aims of Course Medical Parasitology course Provides Student with Aim 1 Knowledge of parasitic diseases; causative parasites (helminthes, protozoa and arthropods), vectors of disease transmission and their pathophysiology. Aim 2 Ability of diagnosis and management of parasitic diseases in an independent manner. Aim 3 Skill of using the microscope efficiently to identify different helminthic, protozoal and arthropods stages especially the diagnostic and infective stages. Aim 4 Basic knowledge of epidemiological and environmental factors and local endemicity of parasites especially in Egypt. Aim 5 Aim 6 Ability to design a simple control and prevention strategy and offer advice for protection against communicable parasitic diseases. Skills of search through the web and team work to conduct and present a research assignment in the area of Medical Parasitology. 2 of 12 2011-2012
2- Intended Learning Outcomes of Course (ILOs) A. Recall of Knowledge and Understanding: By the end of the course, students will be able to: Course ILO Program ILO a1 Define terms related to medical parasitology. A6 a2 a3 a4 a5 a6 a7 a8 a9 a11 a12 a13 a14 Classify parasites of medical importance in its broad scientific taxonomic positions and their habitat in the human body. List the Definitive host, intermediate host and reservoir host if found in case of parasitic infections and zoonosis. Classify arthropods that are mechanical and biological vectors of important human pathogens. Mention arthropods infestations to man as a cause of allergy or as vectors for disease transmission. Relate the life cycle of different parasites of medical importance with pathogenesis (in terms of host- parasite relationship) of different parasitic infections. Correlate the life cycle of different parasites of medical importance in terms of host- parasite relationship to clinical picture. Describe the clinical picture of arthropods infestations to man as a cause of allergy or disease State the mode(s) of infection and transmission of different parasitic and vector borne diseases Describe the infective stage(s) of different parasitic infections and infestations. Enumerate parasites eliciting manifestations in terms of organ(s)/system(s) affection during their migration in the human body. Differentiate between parasites eliciting manifestations in terms of organ(s)/system(s) affection during their migration in the human body. Recognize basic principles of direct methods of laboratory diagnosis with special emphasis on stool, urine and blood examination A6 A6 A6 A6 A6 A8 3 of 12 2011-2012
a15 a16 a17 a18 a19 a20 a21 Describe the diagnostic stage(s) of parasites recovered by direct methods of laboratory diagnosis. Recognize the basic principles of immunological and molecular methods related to the diagnosis of parasitic infections. List anti- parasitic and -arthropods therapy to treat the corresponding infections and infestations important to man. Criticize pitfalls in diagnosis and treatment of parasitic diseases and suggest the proper line of management. Describe methods of prevention and control on an individual and community levels based on the life cycle of the causative parasite. Describe methods of prevention and control of arthropods infestations and vector transmitted diseases based on the ecology of the vector. Compare between different parasites as regards; morphology, geographical distribution, habitat, hosts, pathogensis, clinical picture, management and control. A8 A8 A8 A8 A10 A10 A6 A8 A10 B. Intellectual Skills By the end of the course, students will be able to: b1 b2 b3 b4 b5 Course ILO Correlate the structural and functional alteration due to different parasites with the clinical picture of diseases caused by them in terms of the host parasite relationship. Select appropriate diagnostic methods (direct and indirect) of different parasites according to life cycle. Analyze and Integrate results of history, physical examination and investigations of a case scenario to reach differential diagnosis and diagnosis of the underlying parasitic cause (s). Interpret the geographical distribution for areas where parasites are found (especially endemic areas) as a useful information in the patient history. Construct a simple control and prevention strategy for different parasitic infections in relation to the weak links in the life cycle of the causative parasite. Program ILO B2 B3 B4 B4 B8 4 of 12 2011-2012
C. Professional and Practical Skills By the end of the course, students will be able to: c1 c2 c3 Course ILO Identify different stages of parasites using simple or compound microscope or diagrams and comment on diagnostic, infective stages or vectors of disease transmission. Identify gross samples of some parasites (isolated or within human tissue). Examine to identify pathogenic snails (intermediate hosts of some parasites) that can be of epidemiological importance in Egypt. Program ILO c4 Practice basics of safety procedures during laboratory classes. C6 D. General and Transferable Skills By the end of the course, students will be able to: d1 d2 d3 Course ILO Respect superiors and colleagues during practical classes and small group discussions. Gather, organize and appraise information including the use of information technology where applicable. Present the medical information in written, oral and electronic forms. C1 C1 C1 Program ILO d4 Communicate ideas and arguments effectively. D7 d5 Be prepared for the lifelong learning needs of the medical profession. d6 Work constructively and cooperatively within a team. D9 d7 Practice self and peer evaluation. D10 d8 Effectively manage time. D11 D3 D4 D6 D8 5 of 12 2011-2012
3- Course Contents Topics Teaching and Learning Methods Total % I-GENERAL INTRODUCTION 1 (0.9%) 1 L T (e) P O II- HELMINTHOLOGY Trematodes General characters Fascioliasis /Fasciola species Fasciolopsiasis /Fasciolopsis buski Heterophyiasis /Heterophyes heterophyes Metagonimiasis/ Metagonimus yokogawai Paragonimiasis /Paragonimus westermani Schistosomiasis /Schistosoma species Molluscs Cestodes General characters Diphyllobothriaisis /Diphyllobothrium latum Sparganosis Taeniasis /Taenia saginata and T. solium Cysticercosis Hydatid disease /Echinococcus sp. Hymenolepiasis nana /Hymenolepis nana Hymenolepiasis diminuta/ H. diminuta Dipylidiasis /Dipylidium caninum Nematodes General characters Ascariasis /Ascaris lumbricoides Toxocariasis /Toxocara sp. Enterobiasis/ Enterobius vermicularis Strongyloidiasis /Strongyloides stercoralis Hook worm disease / Hook worm 15 (13.4%) 13 (11.6%) 24 (21.4%) 7 2 6 5 2 6 12 2 10 6 of 12 2011-2012
species Cutaneous larva migrans Trichostrongyliosis/ Trichostrongylus colubriformis Trichuriasis /Trichuris trichiura Intestinal & hepatic Capillariasis/ Capillaria philippinensis and C. hepatica Trichinosis /Trichinella spiralis Filariasis /Wuchereria species, Loiasis/ Loa loa Onchocerciasis/ Onchocerca volvulus Dracunculiasis /Dracunculus medinensis Laboratory techniques of stool, urine 2(1.7%) 2 and blood Examination Revision on Helminthology 2(1.7%) 2 III- PROTOZOOLOGY General introduction Amoebiasis /Amoebae species Free-living amoebae Balantidiasis /Balantidium coli Giardiasis Giardia lamblia Trichomoniasis /Trichomonas vaginalis Leishmaniasis /Leishmania species Trypanosomiasis /Trypanosoma species. Malaria /Plasmodium species Babesiosis /Babesia species Toxoplasmosis /Toxoplasma gondii Sarcocystosis /Sarcocystis species Cryptosporidiosis / Cryptosporidium parvum Isosporiasis /Isospora species IV- ENTOMOLOGY General characters Mosquito species Phlebotomus, Simulium and Culicoides Musca, Stomoxys & Glossina Metallic, Flesh flies & myiasis Bugs Lice Fleas 28 (25%) 17 (15.1%) 16 4 7 2 8 8 7 of 12 2011-2012
Ticks, Mites Cyclops V- Immunity and immuno-diagnosis 1 1 of parasitic diseases (0.9%) VI- Clinical presentations of parasitic 1 1 infections (0. 9%) Revisions 8 2 6 (7.1%) Total 112 (100%) L: lecture, T (e): Tutorial e-sessions, P: Practical, O: Other 54 12 46 4- Teaching and Learning Methods Teaching/ Learning Methods Recall of Knowledge/ Understanding Intellectual skills Professional/ Practical GTS 4.1- Lectures d1 4.2- Tutorial sessions b1-b6 d8 4.3- Practical classes c1-c4 d3,d4,d5, d7,d8 *4.4- E-learning classes b1-6 d1,2,4 **4.5- Self directed learning d1-7 GTS: general transferable skills * Interactive e-classes, on-line lectures, on-line quizzes **Projects and homework assignments Facilities Required for Teaching and Learning Audiovisuals White board Computers 8 of 12 2011-2012
Net Access Microscopes Demo cards for guide learning 5- Teaching and learning methods for students with learning difficulties 1- Revision lectures and tutorial classes outside schedule 2- Assignments 6- Student Assessment Methods 6.1 Methods: Type Assessment Method ILOs Measured Summative Assessment Formative Assessment Continuous Assessment Mid-Year Final Weekly assessments in tutorial sessions On-line quizzes (MCQs) Practical Others Home Assignments Presentations, Projects Written and [MCQ] Written and [MCQ] WRITTEN EXAM PRACTICAL EXAM ORAL EXAM b1- b6 b1- b6 b1-b6 d3-d8 b1-b6 b1-b6 b1-b6 c1-c4 b1-6 d1-2 9 of 12 2011-2012
6.2 Time Schedule Week Weekly Available to students all through the year Weekly All through the year Week 22 Week 6 Week 10 Mid-Year Week 13 Week 22 Week 26 Week 30 Method Formative Assessment: Formative exams in practical sessions Assessments in Tutorials (Computer assisted exam) On-line Quizzes (MCQs) Home Assignments Presentations Projects Continuous Assessment Practical exams (Modified Objective Structured Practical Exam) Written Exam: END of YEAR Multiple Choice Questions Short essay Interpret Problem Solving Oral exam 10 of 12 2011-2012
6.3 Weighing of Assessments Method Weight % Quizzes 6.66% (10 Mark) Continuous Assessment 23.3% Student's Portfolio "Research assignment, attendance, tutorial, drawings and e-learning" 6.66% (10 Mark) Mid-Year Exam Written Exam 10 % (15 Mark) Final Written Exam 53.33% (80 Mark) Finals 76.7% Oral Exam 10 % (15 Mark) Practical Exam 13.33% (20 Mark) Total 100% 150 Mark 11 of 12 2011-2012
7- List of References 7.1 Course Notes Department lecture notes 7.2 Essential Books (Text Books) (Available at department and faculty library) Foundations of Parasitology, Roberts, Larry; Janovy, Jr., John 8th ed. 2009 McGraw-Hill Higher Education Columbus. Medical parasitology Markell E and Vogue J. 9 th ed. 2006 Saunders, Ltd, Toronto 7.3 Recommended Books Basic clinical parasitology, Franklin A. Neva, Harold W. Brown.6th ed. 1994 Appleton & Lange in Norwalk Manson's Tropical Diseases, Cook GC, 22nd ed. 2009 Saunders, Ltd, Toronto 7.4 Periodicals, Web Sites, etc http://telemed.shams.edu.eg/moodle3 http://www.med-chem.com/para/index.htm http://pathmicro.med.sc.edu/book/parasit-sta.htm http://www.dpd.cdc.gov/dpdx/html/para_health.htm http://www.malaria.org/ http://epu-eg.com 7.5 Others Course Coordinator Date Prof. Heba Abdel Aaty Head of Department Prof. Mahmoud El Sebaei 12 of 12 2011-2012