A Joint Effort Regenerative Medicine as Part of a Referral Practice

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A Joint Effort Regenerative Medicine as Part of a Referral Practice James S. Gaynor, DVM, MS, DACVA, DAAPM The Veterinary Specialty Center Colorado Springs, CO USA 719-266-6400 800-791-2578 www.nopetpain.com Our Practice & Our Specialists Anesthesia / Pain Management - 1 Orthopedic Surgery -2 General Surgery - 1 Internal Medicine - 3 Dentistry - 1 Integration - Another Specialized Service To offer current clients To attract new clients To boost the interest in referring vets Not stepping on anyone s toes Another Way To Provide Excellent Care Another Extension of RDVM Practices Case Selection - Clinical Application OA Cases: non-responsive / lack of tolerance to NSAIDs Non-Surgical Candidates Elbows Hips Knees Tarsi Carpi Shoulders Allows for early intervention!

Annie Annie 9 YO FS Lab mix Chronic elbow dysplasia non-nsaid controlled pain IV stem cells at Day 0 and 14. Able to jump in and out of car; took 2 hour run in the woods before her 90 day study exam! Annie Left Right Cinnamon 10 yo MC Std Poodle Bilateral Hip DJD Unable / unwilling to take meds Euthanasia list - new dog in family IA stem cells 30 days - playing, jumping running, walks Cinn photot Rickie 12 yo FS Germ Shep Chronic bilateral elbow DJD IV stem cells at Day 0 and 14. Near normal in clinic Home: depends on husband vs wife, surface for evaluation Rickie photo QuickTime and a TIFF (Uncompressed) decompressor are needed to see this picture.

Marketing Ideas Most vets do not pay attention to mailings REPETITION!!!! Incentive Weekly faxes calling for study dogs EDUCATION!!!!! You are cordially invited to a Special Lecture and Gourmet Dinner April 9, 2007 6-6:30 PM Wine and Building Tours 7:00-8:30 Dinner and Lecture Veterinary Specialty Center Conference Room 5520 North Nevada RSVP 266-6400 Dear Dr. I am pleased to invite you and interested members of your staff to a free evening lecture about regenerative medicine utilizing stem-cell therapy. There will also be a gourmet dinner catered by The Blue Star Restaurant. 10-15 Interested People What Would We Do With Only 5 RSVPs?

90 RSVPs Conference room holds only 30 Expanded to 3 nights over 3 weeks Daily Phone Calls: Study & Commercial Patients Adipose Collection The BEST possible care! Let the owner know Preop blood work Entire process overseen by anesthesiologist VTS-Anesthesia providing anesthesia care Board - certified surgeon ECG Pulse ox ETCO 2 Blood Pressure Adipose Collection General Anesthesia Scapular fat - least problematic Inguinal fat Falciform Local anesthesia - unlikely Epidural anesthesia -> inguinal fat

The Response Incredible! Exciting! What Potential! This could change the way we practice Finally something to help those other patients The natural medicine - oriented owners & vets->very interested Helping the Body Help Itself! Sedation Medetomidine (Domitor ) 0.01 mg/kg ± Hydromorphone 0.1 mg/kg Glycopyrrolate 0.01 mg/kg Oxygen! The Best Possible Care Atipamezole 0.05 mg/kg IV Monitoring ECG OXYGEN Blood pressure The Best Possible Care Technician Elbow Cranial 1. Medial approach 2. Palpate medial epicondyle of humerus 3. Slide finger distal to epicondyle until the approximate level of joint. 4. 20 g needle may be inserted here or just caudal 5. Aspirate for synovial fluid - not always possible

1. Flex hip slightly and position femur parallel to table to open up joint space 2. Flex knee and use tibia as a handle to place traction on hip 3. Palpate hip 4. Insert 22g needle at the midpoint of the proximal edge of the greater trochanter 1. Flex hip slightly and position femur parallel to table to open up joint space 2. Flex knee and use tibia as a handle to place traction on hip 3. Palpate hip 4. Insert 22g needle at the midpoint of the proximal edge of the greater trochanter Contrast in CF joint Needle in CF joint Positioning of Hip 1. Place leg in extension or slight flexion 2. Palpate patellar tendon 3. Insert 22g needle 1/3 of the way between the medial (lateral) aspect of the patellar tendon and the medial (lateral) aspect of the joint

Further Information Knee Lateral 1. Palpate acromial process of the scapula 2. Insert needle in a perpendicular fashion just craniodistal to the acromion 3. Aspirate for synovial fluid Lateral Final Words Exciting prospects Educate the referral base Practice the technique Assure the highest quality medicine For Consultation 719-266-6400 800-791-2578 www.nopetpain.com