European Antibiotic Awareness Day

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Initiating a pan-european health campaign - experiences from setting up the European Antibiotic Awareness Day Dr Ülla-Karin Nurm Head of Public Health Development Section, Public Health Capacity and Communication Unit, European Centre for Disease Prevention and Control, Stockholm (Sweden). HEALTH 11-12 April 2011 Citywest Hotel, Dublin, Ireland European Antibiotic Awareness Day Dr. Ülla-Karin Nurm, senior expert, head of section Public Health Capacity and Communication Unit European Centre for Disease Prevention and Control (ECDC) Dublin, April 4th, 2011 1

What is ECDC? "An independent agency, named the European Centre for Disease Prevention and Control " ECDC Founding Regulation (851/2004) European Union Agency which: is a member of the European Union (EU) family; covers EU 27, EEA/EFTA countries; reaches out to other countries beyond the EU 27 through Neighbourhood Policy and DG RELEX; has the mission to identify, assess and communicate current and emerging threats to human health posed by infectious diseases; is financed through EU budget; is based in Stockholm, Sweden. What is the problem? Misuse of antibiotics Threat to patient safety Limited options for treatment Poor implementation of hygienic measures Increased length of hospital stays Increased patient morbidity and mortality 2

DDD per 1000 inhabitants and per day The Bacterial Challenge: new antibiotics pipeline is virtually empty Main actions: focus on behaviour Behaviour 1 Prudent use of antimicrobials (only when needed, correct dose, dose intervals, duration) Behaviour 2 Infection control (hand hygiene, screening, isolation) Total outpatient antibiotic use in EU Member States, Iceland and Norway, 2008 50 45 40 Penicillins (J01C) Cephalosporins and other beta-lactams (J01D) Tetracyclines (J01A) Macrolides, lincosamides and streptogramins (J01F) 35 30 Quinolones (J01M) Sulfonamides and trimethoprim (J01E) Other J01 classes 25 20 15 10 5 0 GR* CY* IT FR BE LU LT* SK PT IE IL PL IS BG ES** FI MT*** CZ UK DK NO HU SI AT SE DE EE NL LV * Total use, i.e. including inpatients (CY, GR, LT). ** Reimbursement data, i.e. not including over-the-counter sales without a prescription (ES) *** Data from 2007 (MT) Source: European Surveillance of Antimicrobial Consumption (ESAC), 2010. In: ECDC Annual Epidemiological Report 2010: in press. 3

Staphylococcus aureus: proportion of invasive isolates resistant to meticillin (MRSA), 2009 Source: EARS-Net, 2010. The symbols and indicate a significant increasing or decreasing trend for the period 2006-2009, respectively. These trends were calculated on laboratories that consistently reported during 2006-2009. Knowledge about antibiotics The majority of Europeans believe that antibiotics act against viruses For each of the following statements, please tell me whether you think it is true or false: Antibiotics kill viruses True False Don t know Special Eurobarometer 338 (EB 72.5) 2009 4

Target Audience / Customer? Who is influencing antibiotic consumption? Patients many people think that antibiotics are effective against colds and flu Primary care prescribers major differences in antibiotic prescribing for coughs and colds across Europe Hospital prescribers major differences in dosing and duration of antibiotic therapy in hospitals across Europe 5

Animated slide: Press key Toolkit for hospital prescribers: information materials Web banner Advertorial Fact sheet Check list PPT Presentation Screen saver 6

TV and web spots Available from:http://antibiotic.ecdc.europa.eu Case study on EEAD: National prudent antibiotic use campaign Belgium 7

Objectives of national campaign in Belgium Knowledge: antibiotics not active against viruses Attitude: antibiotics not for common cold, acute bronchitis and flu Behaviour: do not take antibiotics for common cold, acute bronchitis and flu Was the public ready for the campaign? Pre-campaign study by specialized agency among 1,000 persons Large misunderstanding or lack of information about the real conditions for usefulness of antibiotics in current infections Belief that antibiotics will allow a faster cure for even minor infections Great confidence of the public in doctors and pharmacists Doctors tend to overestimate the patients' pressure for antibiotics 8

Campaign activities Letter to the health professionals Brochures and folders TV spot Web sites Belgium organised 3 different awareness campaigns 2000 2003 (3 winters) 2004 2008 (4 winters) 2008 (launched 18.11.08) 9

Evaluation of the Belgian National Campaigns Process evaluation Impact evaluation The awareness of the public The appreciation of the campaigns by the GPs Antibiotic prescription at the community level Cost/saving Outcome evaluation Antibiotic resistance in the community Awareness of the public after the 1st campaign (2 of 2) Main and most salient results concerning individual AB use : (in comparison with a similar pre-campaign survey) Do you agree to use less AB in agreement with your GP? Yes 64 % 75 % S Why? To limit overuse To preserve their efficacy 20 % 26 % 13 % 25 % pre-campaign post-campaign S = p < 0.05 17 10

Appreciation by the General Practitioners the first two campaigns (2 of 2) Did they change anything in their practice?... after I have changed... 33 % 38 % And if they changed, how did they change?... I effectively have 32 % prescribed less AB 63 % key 1st campaign 2d campaign 22 Behavioural impact: Belgian Campaigns 2002-2010 Outpatient antibiotic use in Belgium in packages per 1,000 inhabitants per day July - June 11

Objectives & activities for 2011 Training module on development, implementation & evaluation of national campaigns Guidance on how to adapt EAAD key messages and materials for use on social media Intensify cooperation with stakeholders and patient groups and develop patient stories Futuris episode on prudent antibiotic use with Euronews Media toolkit including preview of new Europewide data Partner major initiatives, e.g. WHD, TATFAR, Get Smart, EC AMR Strategy Protecting Europe's health 90 12

Questions Please wait for the microphone and state your name and organisation before asking your question 11-12 April 2011 Citywest Hotel, Dublin, Ireland 11-12 April 2011 Citywest Hotel, Dublin, Ireland 13