Successful Antimicrobial Stewardship in a Multihospital System: Tools You Can Use

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Successful Antimicrobial Stewardship in a Multihospital System: Tools You Can Use Justin Schmetterer, PharmD Infectious Disease Specialist jschmette2@phs.org 505-724-7146 Disclosure Relevant Financial Relationships: Receives financial compensation for serving in Allergan Speaker Bureau Dalvance (dalbavancin) Teflaro (ceftaroline) Avycaz (ceftazidime/ avibactam) 2 1

Goals Pharmacist Objectives Identify key team members in an ideal Antimicrobial Stewardship Program (ASP) Identify barriers to establishing an ideal ASP Develop methods to tailor your ASP to your specific facility Develop methods and tools to optimize your current ASP model with limited resources Pharmacy Technician Objectives Identify opportunities for technicians to get involved in ASPs Discover ways to spread educational tools for patients utilizing CDC Get Smart Understand the roles and responsibilities of members in an ideal ASP 3 Ideal ASP 4 2

PHS ASP Team 5 PHS Model 6 3

7 ASP Team: Small Hospital 8 4

ASP Team: Large Hospital 9 Where to start? Identify key stakeholders Easier said than done. Communicate! Include hospitalists, pulmonology etc. Why ASP? Metrics - DOT/1000 patient days Identify outliers/high utilization perform MUE/DUE Purchasing data? Preauthorization/restriction or prospective audit feedback? PHS uses combination Develop clinical pathways and protocols Don t have any? Have them available electronically ASP can t run 24/7 Low hanging fruit 10 5

Exploit Technology 11 So you re ready to work up cases? 12 6

Patient workup You need the right approach! 13 ASP Tool- Patient Workup Template 14 7

ASP Tool- Patient Workup Template 15 ASP Tool- Patient Workup Template 16 8

Leukocytosis 17 Leukocytosis 18 9

Fever 19 Medications that cause drug fever 20 10

21 ASP Tool- Patient Workup Template 22 11

The Art of An Intervention Know Your Audience!! Know Your Patient Timing Clinical vs Interpersonal Skills First Impression Crucial 23 Document, Document, Document 24 12

Example Linezolid Regionals 25 Additional Tools/Ideas to Help 1.) Under apps store search Castbox 2.) Install Castbox onto device 3.) In main menu select the Search podcast 4.) Type Infectious disease 5.) Select the plus symbol to subscribe 26 13

Additional Tools/Ideas to Help IDSA Guidelines- Implementing ASP Telemedicine ID physician contracting for ASP rounds/training? ECHO program SIDP/MAD ID ASP Training Acceptable entry level ASP Suboptimal for high level functions Webinars/Conferences ID week SIDP MAD-ID 27 Conclusion: Remember it s easy! 28 14

References Implementing an Antibiotic Stewardship Program: Guidelines by the Infectious Disease Society of America and the Society of Healthcare Epidemiology of America https://academic.oup.com/cid/article-lookup/62/10/e51 Gross R, et al. Impact of a hospital-based antimicrobial management program on clinical and economic outcomes. Clin Infect Dis. 2001 Aug 1;33(3):289-95. Epub 2001 Jul 5. Struelens M, et al. Multidisciplinary antimicrobial management teams: the way forward to control antimicrobial resistance in hospitals. Current Opinion in Infectious Diseases. 16(4):305-7, AUG 2003. Deliit T, et al. Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America guidelines for developing an institutional program to enhance antimicrobial stewardship. Clin Infect Dis. 2007 Jan 15;44(2):159-77. Epub 2006 Dec 13. Core Elements of Hospital Stewardship Programs from the Centers for Disease Control www.cdc.gov/getsmart/healthcare/pdfs/checklist.pdf 29 Antimicrobial Stewardship Outreach Larissa K. Chin, PharmD, MBA PGY2 Infectious Disease Pharmacy Resident Presbyterian Healthcare Services LChin2@phs.org 15

Disclosure Larissa Chin, PharmD, MBA, PGY2 Pharmacy Resident Disclosure: No relevant financial or nonfinancial relationships to disclose 31 Objectives Identify challenges to antimicrobial stewardship activities Explain how the Centers for Disease Control (CDC) can help raise antibiotic awareness Discover tools you can use to promote your own antimicrobial stewardship activities 32 16

Importance of Stewardship According to the CDC, over 2 million people per year are infected with a resistant bacterial organism At least 23,000 will die due to those infections Resistant organisms, such as Carbapenem-resistant Enterobacteriaceae are increasing in prevalence The CDC works to highlight these global concerns by providing educational tools on the safe and proper use of antibiotics CDC. U.S. Antibiotic Awareness Week. 2017. CDC. Healthcare-associated infections. 2017. 33 Antimicrobial Stewardship Challenges Lack of engagement https://midlifemacgyver.files.wordpress.com/2015/08/challenge.jpg Too much time/energy to maintain Patient and provider educational challenges Not enough trained or specialized personnel https://www.cdc.gov/vitalsigns/pdf/2014-03-vitalsigns.pdf 34 17

CDC: Get Smart About Antibiotics Week November 13 19, 2017 A week designed to raise antibiotic awareness, and provide tools for long-lasting antimicrobial stewardship success Involve your local pharmacists, pharmacy technicians, practitioners, and patients! CDC. U.S. Antibiotic Awareness Week. 2017. 35 Provide your administration with the facts about the benefits of antimicrobial stewardship Highlight the benefits of antimicrobial stewardship Promote Best Practices 1. Order recommended cultures prior to antibiotic administration 2. Make sure indication, dose and expected duration are specified in the patient record 3. Reassess within 48 hours of starting antibiotics https://www.cdc.gov/getsmart/community/materials-references/print-materials/hcp/index.html 36 18

Educational Material The CDC provides free educational resources for patients and healthcare providers https://www.cdc.gov/getsmart/community/materials-references/print-materials/everyone/index.html 37 https://www.cdc.gov/media/dpk/2013/images/untreatable/img1.jpg 38 19

https://www.cdc.gov/getsmart/community/for-patients/common-illnesses/bronchitis.html 39 https://www.cdc.gov/getsmart/week/promotional-materials/graphics.html 40 20

Activity Ideas For Your Institution Provide educational material to patients Post social media messages Distribute tools and guidelines to healthcare professionals http://www.bp.com/en/global/corporate/media/social-media.html Use engaging activities to highlight stewardship initiatives Create fun, short videos that highlight your mission CDC. U.S. Antibiotic Awareness Week. 2017. 41 Kids Health Fair 42 21

ZDoggMD on YouTube http://zdoggmd.com/about-z/ 43 Creating Lasting Effects Use the CDC Get Smart About Antibiotics Week to promote your antimicrobial stewardship activities Continue that momentum by engaging with your pharmacists, practitioners, and patients Get involved! http://transmartfoundation.org/getinvolved/ 44 22

Summary Employ CDC strategies and resources Promote your Antimicrobial Stewardship activities throughout your organization Ask other institutions for ideas 45 Thank you for your time and attention Larissa K. Chin, PharmD, MBA PGY2 Infectious Disease Pharmacy Resident Presbyterian Healthcare Services LChin2@phs.org 46 23