Metronidazole Albendazole giardiasis 5 (1) 6 Piperlongum 7 Yucca schidigera 8 4 TM Doxal Higro) Logoul s sol. (Medazole) MacMaster ZnSo4 TA
C 10 day zero Cyst per Gram 9
TM C )
pasture pipette ttest
TM TA Control ttest P TA TM M SE p (9)
TM M SE TA M SE C M SE 13 9 60 reinfection Gardia lamblia Albendazole Radostits,O.M.;Gay,C.C.;Blood, D.C. and Hinchliff, K.W.(1999).Veterinary Medicine :A Textbook of the disease of Cattle,Sheep,Pigs,Goats and Horses.9 th Ed.W.B.Saunders Co.,London Pp:13141316. Rose,J.B. and Slifko,T.R. (1999) Giardia, Cryptosporidium and Cyclospora and their impact on food :A review.j.food Prot.62(9):10591070. OHandley, R.M.; Cockwill, C. M.J.; McAllister, T.A. and Olson, M.E. (2000).Effect of repeat fenbendazole treatment in dairy calves with giardiasis.vet.parasitol. 89:209218.
Farthing,M.J.G. (1999). Giardiasis. In: Protozoal Diseases.(ed). Gilles, H.M. Oxford university Press inc.london.pp.:562578. OHandley,R.M.;Buret,A.G.;mCaLLISTER,t. a. Jelinski, M. and Olson, M.E. (2001).Giardiasis in dairy Calves:Effects of Fenbendazole treatment on Intestinal structure and function.int.parasitol.31(1):73 79. Gardner,T.B.and Hill,D.R.(2001).Treatment of giardiasis. Clin. Microbiol. Reviews.14(1):114128. Tripathi,D.M.;Gupta,N.;Lakshmi,V.;Saxena, K.C.and Agrawal,A.K. (1999). Antigiardial and immunostimulatory effect of piper longum on giardiasis due to Giardia Lamblia.Phytother.Res.,13(7):561 565. McAllister,T.and Coulter,G.H.(2001).Desert plant shows promise for controlling Giardiasis. http://res 2.agar.Ca/ Lethbridge. St.Jean,G.; Couture,Y. Dubreuil,P.and Frechette,J.L (1987).Diagnosis of Giardia Infection in 14 Calves. J.A.V.M.A.191(7):831832. Xiao,L.,Saeed,K. and Herd,R.P. (1996). Efficacy of albendazole and fenbendazole against Giardia infection in cattle. Vet. Parasitol.61(12):165170. Kulda,J.and Nohynkova,E.(1978).Flagellates of the human intestine and Intestine of other Species.In:Parasitic protozoa.(ed).krier,j.p.academic press,newyork and London.2:69 104. Permin,A. and Hansen, J.W.(1998). Epidemiology, Diagnosis and Control of Poultry parasites. FAO, Rome,Italy.Pp:8999. Xiao,L.;Herd,R.P.and Rings,D.M. (1993). Concurrent infections of Giardia Cryptosporidium on two Ohio farms with calf diarrhea.vet.parasitol.51(12):41 48. Farbey,M.D.; Reynoldson, J.A. and Thompson, R.C.A.(1995).In vitro drug susceptibility of 29 Isolates of Giardia duodenalis from humans as assessd by an adhesion assay. Int.Parasitol.25(5):593599. Zaat,J.O.M.;Mank,Th.G. and Assendelft, W.J.J.(1997).A systemic review on the treatment of giardiasis. Trop.Med.Int.Health.2(1):6382. Frisby,H.;Foster and smith.(2002)giardia (Giardia Canis, Giardia cati). http://www.critterhaven.org/critter chat/giardia fands.htm. Ortiz,J.J.; Ayoub,A.; Gargala,G.; Chegne, N.L. and Favennec,L. (2001). Randomized clinical study of nitazoxanide compared to metronidazole in the treatment of symptomatic giardiasis in children from Northern Peru. Aliment. Pharmacol. Ther.15:14091415. Stinger,D.A. and Babyn,P.S.(2000).Pediatric gastrointestinal Imaging and Intervention.2 nd Ed.B.C. Decker Inc.Canada.Pp:5051. Barr,S.C.; Bowmann,D.D.; Heller,R.L. and Erb.H.N.(1993).Efficacy of Albendazole against giardiasis in dogs.a.j.vet.res.54(6):988990. Bowmann,D.D. and Lynn,R.C. (1995). Georgi s parasitology for Veterinarians. W.B. Saunders company,philaedelphia,u.s.a.pp:8 789. Reynoldson,J.A.;Behnke,J.M.;Horton,R.J.;S pargo, R.; Hopkins, R.M.; Constantine, C.C.; Gilbert, F.; Stead,C.; Hobbs,R.P. and Thompson,R.C.A. (1998). Efficacy of Albendazole against Giardia and Hookworm in aremote Aboriginal
Community in the north of Western Australia.Acta Tropica.71:2744. Misra,P.K.; Kumar,A.; Agarwal,V. and Jagota,S.C.(1995).Acomparative clinical trial of albendazole versus metronidazole in giardiasis Ind. Pediatr.32(3):291294. Lemee,V.; Zaharia,L.; Nevez,G.; Rabodonirina,M.; Brasseur, Ballet, J.J. and Favennec, L. (2000). Metronidazole and Albendazole susceptibility of 11 clinical isolates of Giardia duodenalis from France.J.Antimicrob.46:819821. Clinical study about using metronidazole and Albendazole in treatment of giardiasis in cows Q. H.Kshash Col. of Vet. Med./ Unv. of AL.Qadysia Abstract The present study was conducted to evaluate the efficacy of metronidazole (50 mg/kg B.w daily for five days) Albendazole(20 mg/kg. B.w daily for three consective days. In treatment of giardiasis in cows and then compared between their therapeutic efficacies. The results were showing a good efficacy of both drugs in treatment. Albendazole is more effective than Metronidazole in giardiasis treatment. The therapeutic efficacy of Albendazole was (%98,%96,%91), while metronidazole was (%99,%90,%80) at 1,2,6 weeks after treatment respectively.