Antimicrobial Use Toolkit Webinar M A R C H 1 3,

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Antimicrobial Use Toolkit Webinar M A R C H 1 3, 2 0 1 8

Welcome & Housekeeping Thank you for attending! HMS data abstractors Administrators QI staff Pharmacists Hospitalists ID physicians Individuals not affiliated with HMS Q & A session following presentation All phones muted Please raise your hand using the webinar software or type your question

Michigan Hospital Medicine Safety (HMS) Consortium S C O T T F L A N D E R S, M D

HMS: Collaborative Quality Initiative HMS: 1 of 17 CQIs in Michigan Funding: Blue Cross Blue Shield of Michigan Coordinating Center.85 FTE data abstraction per hospital Pay for performance Michigan hospitals voluntarily enroll

HMS Hospitals 43 hospitals Diverse types / settings Large AMCs-Small rural hospitals Hospital Participants Physician Champion-hospitalist Quality Lead Data Abstractor Improving Care Data / best practice sharing / facilitated implementation

HMS Antimicrobial Use Initiative Antimicrobial use data collection began winter 2017 ~18,000 cases Key areas of focus Urinary Tract Infection (UTI)/Asymptomatic Bacteriuria Community Acquired Pneumonia (CAP) and Healthcare- Associated Pneumonia (HCAP) Several areas of improvement have been identified across the collaborative

HMS Antimicrobial Use Initiative Pneumonia (CAP / HCAP-MDRO risk factors) Admission decision (CAP) Initial empiric rx Fluoroquinolone-non-preferred Diagnostic testing De-escalation Treatment duration UTI (uncomplicated / complicated / ASB) Diagnostic testing (ASB) Unnecessary treatment (ASB) Initial empiric rx Fluoroquinolone non-preferred De-escalation Treatment duration Urinary catheter appropriateness

Uncomplicated CAP Treated for 5 Days Collaborative Mean = 22% Desired Trend Considered appropriate if 6 or fewer days of antibiotic treatment 2018 Performance Goal Blue= Low Volume

Asymptomatic Bacteriuria % of UTI Cases-Overtesting Collaborative Mean = 32% 2018 Performance Goal Desired Trend Blue = Low Volume

Asymptomatic Bacteriuria % Treated * * * * * * * Collaborative Mean Receiving Any Antibiotic = 81.8% Receiving a Fluoroquinolone = 27.5% * * 2018 Performance Goal * Desired Trend *= Low Volume

HCAP Broad Antibiotic Coverage No Culture or Negative Cultures by Hospital- Day 4 Collaborative mean= 62% * *= Low Volume * * * *Broad Coverage= MRSA and/or Pseudomonas (includes antipseudomonal beta lactams and fluoroquinolones)

Antimicrobial Use Toolkit L I N D S A Y P E T T Y, M D T E J A L G A N D H I, M D

Antimicrobial Use Toolkit Key strategies to improve antimicrobial use globally Developed in partnership with BCBSM & the CDC

Toolkit Available via HMS Website Toolkit is available on the HMS website http://mi-hms.org/hms-antibiotic-toolkit Highlight key tools during today s webinar

HMS Antimicrobial Toolkit Quick Reference Guide

Strategy #1: Convene a Workgroup to Focus on Tier 1 Strategies Subgroup of current antimicrobial stewardship team Key members Hospitalist, ID physician, ID pharmacist, ER physician, house officers, nursing, IT, and microbiology lab personnel Meet quarterly and implement at least two new interventions per year Assess post-intervention and make modifications

Strategy #1: Convene a Workgroup to Focus on Tier 1 Strategies Resources provided emphasize the importance of involving key stakeholders

Strategy #2: Develop and Share Institutional Guidelines for UTI and CAP Develop institutional guidelines Locally-adapted from national and HMS guidelines CAP and UTI If guidelines already exist, ensure guidelines match recommendations Share the guidelines in multiple formats and get feedback from the frontline providers

Strategy #2: Develop and Share Institutional Guidelines for UTI and CAP Links to National Guidelines (IDSA) HMS treatment guidelines for CAP and UTI Example of institutional guidelines Sample pocket cards for ASB and CAP Educational screensaver

Strategy #2: Develop and Share Institutional Guidelines for UTI and CAP Sample Guideline Resource provided highlighting key areas to modify existing guidelines Consistent with National & HMS Guidelines Improve in HMS performance measures Example of Institutional Guideline for CAP

Strategy #2: Develop and Share Institutional Guidelines for UTI and CAP CAP Pocket Card Front Back Suggested Use of the Tool Provide a copy to providers (printed or electronic) Print poster size version and post in work rooms *Sites can add Hospital Logo for Distribution

Strategy #2: Develop and Share Institutional Guidelines for UTI and CAP UTI Pocket Card Front Back *Can add Hospital Logo for Distribution

Strategy #2: Develop and Share Institutional Guidelines for UTI and CAP Example of Educational Screensaver for Hospital Computers Promotes/Educates Use of Guidelines Provides Reference to Guideline

Strategy #3: Integrate and Operationalize Institutional Guidelines for UTI and CAP Education for providers, patients and families Integrate recommendations into key processes (i.e. order sets, discharge planning, etc.) Obtain provider feedback after 3 months of guideline use Involve hospitalist champions in education and dissemination

Strategy #3: Integrate and Operationalize Institutional Guidelines for UTI and CAP Example CAP & UTI Order Set Example patient education brochure

Strategy #3: Integrate and Operationalize Institutional Guidelines for UTI and CAP Antibiotic Patient Education Brochure Example Order Set

Strategy #4: Reduce Duration of ABX Treatment for Uncomplicated CAP to 5 Days Educate providers Evaluate differences in provider groups Documentation of dose/indication/duration 72-hour time out Efforts focused on discharge prescribing Audit & Feedback

Strategy #4: Reduce Duration of ABX Treatment for Uncomplicated CAP to 5 Days 3 component intervention to reduce CAP treatment duration Survey to assess knowledge/practices related to the treatment of patients with CAP Educational lecture including survey results & evidence-based guidelines Prospective audit & feedback by pharmacists

Strategy #4: Reduce Duration of ABX Treatment for Uncomplicated CAP to 5 Days Tool to improve antibiotic prescribing at hospital discharge CAP educational video (for providers) Antibiotic time out checklist (72-hour time out) Sample hospital newsletter Sample audit & feedback emails

Strategy #4: Reduce Duration of ABX Treatment for Uncomplicated CAP to 5 Days Sample Hospital Newsletter HMS data to highlight hospital specific area for improvement Reviews the current guidelines Highlights the take away messages

Strategy #4: Reduce Duration of ABX Treatment for Uncomplicated CAP to 5 Days Tool to Improve Antibiotic Prescribing at Discharge D.I.S.Ch.A.R.G.E Defaults and Order Sets Incentivize Discharge Summary Checklist Audit and Feedback Review Guidelines Educate Good summary of interventions targeting improvement in discharge prescribing of antibiotics

Strategy #4: Reduce Duration of ABX Treatment for Uncomplicated CAP to 5 Days CAP Duration Audit & Feedback: Top Performer Sample Email CAP Duration Audit & Feedback: Prolonged Duration Sample Email

Strategy #5: Reduce Testing and Treatment of Asymptomatic Bacteriuria (ASB) Educate providers Evaluate differences in provider groups Checklists for ordering urine cultures Documentation of dose/indication/duration Create a protocol for assessing patients with AMS as the only symptom AMS is the only symptom for ~30% of patients with a positive urine culture

Strategy #5: Reduce Testing and Treatment of Asymptomatic Bacteriuria (ASB) Resource detailing potential intervention Positive results from noncatheterized specimens were no longer automatically reported Instead, a message (see below) was provided to contact the lab Tx ASB 48% 12% Abs Risk Reduction 36%

Strategy #5: Reduce Testing and Treatment of Asymptomatic Bacteriuria (ASB) Educational Videos (Nurses, Providers) Checklist for appropriate urine culture ordering Flowchart for management of patients with AMS

Strategy #5: Reduce Testing and Treatment of Asymptomatic Bacteriuria (ASB) Flowchart for the Management of Patients with AMS Provides a resource for providers to utilize when AMS is the only symptom of a potential UTI Recommends other treatment options prior to sending urinalysis or culture

Strategy #5: Reduce Testing and Treatment of Asymptomatic Bacteriuria (ASB) Flowchart for the Management of Patients with AMS If urine culture is negative, evaluate for other causes of AMS

Strategy #5: Reduce Testing and Treatment of Asymptomatic Bacteriuria (ASB) For testing, target more than prescribers also target nurses! https://discover.explaineverything.com/discover/thecode/jtmdjat

Strategy #6: De-escalate Antibiotic Treatment for UTI and Pneumonia 72-hour time outs Utilize pharmacists to review cultures and ensure appropriate antibiotic prescribing Audit/feedback to providers

Strategy #6: De-escalate Antibiotic Treatment for UTI and Pneumonia De-escalation quick reference guide for pharmacists Antibiotic indications for pharmacists Antibiotic Time Out Checklist

Strategy #6: De-escalate Antibiotic Treatment for UTI and Pneumonia Antibiotic Time-Out Checklist Prompts the questions needed to review during an Abx Time Out Suggested Use of the Tool Utilize as a checklist during pharmacist rounds Print poster size version and post in work rooms

Strategy #6: De-escalate Antibiotic Treatment for UTI and Pneumonia De-escalation Quick Reference Guide for Pharmacists Defines deescalation Details 6 steps to determine whether de-escalation is appropriate Emphasizes the pharmacists role in de-escalation

How to Use the HMS Antimicrobial Use Toolkit Toolkit covers multiple problem areas Select tools that fit your organizations needs and addresses your hospital specific problem areas This toolkit is a live document and will continually be updated as new tools/interventions are developed If you have tools to be added to the toolkit please contact hospmedqi@umich.edu Hospital specific examples will be added over time

How to Access the HMS Antimicrobial Use Toolkit Toolkit available on the HMS website http://mi-hms.org/hms-antibiotic-toolkit Formats PDF Version (print, email, etc) Electronic version (mobile friendly) Option on HMS website to add hospital logo for select tools http://mi-hms.org/resources/hms-quality-initiativetoolkits/hms-antimicrobial-toolkit

How to Access the HMS Antimicrobial Use Toolkit Select a strategy for the resources, tools & references

Next Steps- How to Get Started Step 1: Convene workgroup Step 2: Review HMS data to determine opportunities for improvement Step 3: If local guidelines exist, compare guidelines and make modifications, if necessary If no local guidelines, develop institution guidelines Step 4: Select 2 tools to implement during the next year *Resource provided in toolkit

Thank You! We would like to thank the following individuals for their support in developing this toolkit Sarah Bloemers Tawny Apsley Jennifer Minock Valerie Vaughn Danny Nielsen Anna Conlon McLaren Lapeer St. Joseph Mercy Health System Beaumont Farmington Hills Intermountain Health Members of the data, design and publications committee We could not have launched the toolkit without you!

Questions?