OIE activities on rabies: PVS, vaccine banks and the OIE twinning

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Dr Gardner Murray, Special Adviser World Organisation for Animal Health (OIE) OIE activities on rabies: PVS, vaccine banks and the OIE twinning OIE Global Conference on Rabies Control: with the support of WHO and FAO Towards Sustainable Prevention at the Source 7-9 September, 2011, Incheon-Seoul, Republic of Korea 1

2 Source: TravelPod

Approach Introduction Performance of Veterinary Services (PVS) Vaccination Twinning Conclusions

Introduction (1/3) Discussions so far have dealt with Global situation, science, economics, rabies control, standards, stakeholders OIE emphasises the importance of control and eradication at source, primarily dogs Using tools such as vaccination, education, stakeholder engagement

Introduction (2/3) A key direction of the OIE 2011-2015 Strategy is One Health to support the reduction and management of risk at the animal/human/ecosystems interface And strategic objectives relating to Good governance and capacity building of veterinary services (VS) and The development and implementation of scientifically based standards

Introduction (3/3) OIE strategies support immediate actions, a staged approach, as well as facilitating long term maintenance and improvements to rabies control programs That is sustainability The presentation will focus on only 3 components of OIE work PVS, vaccination, and twinning

PVS (1/15) One of the main levers for providing practical help to strengthen VS is to put in place sound governance, structural and procedural arrangements Using the PVS Tool, PVS Gap Analysis (GA), and PVS follow-up The PVS Tool is a mechanism to evaluate performance of VS and promote a culture of awareness And sustained interactions with the public/private sectors

The OIE-PVS Tool (2/15) Evaluation of the Performance of Veterinary Services a tool for Good Governance of Veterinary Services Objective: 120 Countries This global tool provided by the OIE will has a great impact on the promotion and improvement of Veterinary Services worldwide

OIE PVS Tool: Structure (3/15) PVS 4 Fundamental Components Human, physical and Human, financial physical resources and financial resources Technical authority Technical and capability authority and capability Interaction with stakeholders Access to market 46 Critical Competencies, included in the 2010 edition: management systems; animal welfare; And evaluation of the performance of Aquatic Animal Health Services (as part of a PVS evaluation of Veterinary Services, or as an independent exercise). 5 Levels of Advancement : Level 1 = No compliance; Level 5 = Full compliance with OIE standards A higher level assumes compliance with all preceding levels

Critical competencies (4/15) I. HUMAN, PHYSICAL AND FINANCIAL RESOURCES 1. Professional and technical staffing of the Veterinary Services 2. Competencies of veterinarians and veterinary para-professionals 3. Continuing education 4. Technical independence 5. Stability of structures and sustainability of policies 6. Coordination capability of the sectors and institutions of the Veterinary Services 7. Physical resources 8. Funding 9. Contingency and compensatory funding 10. Capability to invest and develop

PVS (5/15) The GA is a follow-up activity to analyse the results of the evaluation And helps identify priorities for action and prepare investment programs for national/international support PVS follow-up evaluation missions help assess progress post investments

PVS (6/15) OIE facilitation to countries to transform results of Gap Analysis into Veterinary Services (VS) Strategic Plans Pilots in Vietnam and Philippines under the AusAID Programme for Strengthening Veterinary Services (PSVS)

PVS (7/15) Source: www.greenwichmeantime.com

PVS (8/15) Source: www.greenwichmeantime.com

The OIE PVS Pathway (9/15) «Treatment» Specific Activities, Projects and Programs Veterinary Legislation «Diagnosis» «Prescription» PVS Evaluation PVS Gap Analysis incl. VS Strategic Priorities Public / Private Partnerships Veterinary Education PVS Pathway Follow-Up Missions The OIE collaborates with governments, stakeholders and donors Laboratories

The OIE PVS Pathway today (10/15) PVS 217 Certified Experts 105 Missions done Legislation 31 Certified Experts 20 Missions done PVS Gap Analysis 81 Certified Experts 38 Missions done

PVS Evaluation Missions State of play (11/15) OIE Members PVS Evaluations requests received PVS Evaluations missions implemented Reports available for (resrtricted) distribution to Donors and Partners Africa 52 50 45 35 Americas 29 22 20 16 Asia, the Far East and Oceania 32 18 15 11 Europe 53 14 13 10 Middle East 12 12 11 5 TOTAL 178 116 104 77 As of 26 August 2011

Overview of PVS Evaluation missions (12/15) Missions requests Mission completed 26/08/2011 Reports Available

PVS Gap Analysis Missions State of play (13/15) OIE Members PVS Gap Analysis requests received PVS Gap Analysis missions implemented PVS Gap Analysis missions reports received Africa 52 31 21 19 Americas 29 11 6 5 Asia, the Far East and Oceania 32 12 8 7 Europe 53 6 5 3 Middle East 12 7 2 2 TOTAL 178 67 42 36 As of 26 August 2011

26/08/2011 Overview of PVS Gap Analysis missions (14/15) Missions requests Mission completed Reports Available

PVS (15/15) Given VS are at the front line of animal health including zoonotic activities ongoing improvements can support sustainable rabies prevention and control systems PVS components will continue to be expanded to cover new areas e.g. wildlife management services relevant to animal health, a Pilot on One health And PVS follow-up activities will ensure countries are up-to-date with the newest developments

Rabies Vaccine Bank (1/6) Successful rabies control/eradication requires management at the animal source Focus on containment and eventual eradication especially in dogs Using vaccination tools And multi sectoral/disciplinary coordination Baits, if successful, could improve vaccine coverage in certain situations

Rabies Vaccine Bank (2/6) Rabies vaccination Credits: BAI, Philippines

Rabies Vaccine Bank (3/6) Would there be value in establishing Rabies Vaccine Bank(s)? OIE has initiated the establishment of Vaccine Banks for AI and FMD OIE is developing an EU funded Rabies Vaccine Bank And a pilot activity from its Bangkok Office

Rabies Vaccine Bank (4/6) Vaccines would comply with international standards and be provided by OIE to partner countries for emergency/other uses Leverage to support vaccine supply by others is an objective

Rabies Vaccine Bank (5/6) The next steps are that OIE will Establish the Rabies Vaccine Bank after finalizing form, vaccine requirements, criteria for use and modus operandi Discuss with partners potential pilot program objectives, expected benefits and methodologies

Stop Transboundary Animal Diseases and Zoonoses (STANDZ) Initiative The new AusAID funded STANDZ Program (2011-2016) will have a One Health activity to support countries in the development and establishment of cross sectoral control strategies for rabies STANDZ will be managed by the OIE Sub Regional representation in Bangkok and will operate in ASEAN countries but with close linkages to ASEAN plus 3 and the HPED Program

Twinning (1/12) Twinning is integral to capacity building for VS and has the objective of Improving expertise and diagnostic capacity in countries, meeting OIE Standards, and in the case of some, becoming OIE Reference Laboratories (RL) and Collaborating Centres (CC) Twinning provides a link between RL or CC (the Parent) and laboratory or institution (the Candidate) in a country

Twinning (2/12) OIE RLs are designated to pursue technical and scientific issues relating to a named disease or topic And function as centres of expertise and standardization of diagnostic techniques OIE CCs operate as centres of research, expertise, standardization, and dissemination of techniques in their sphere of competence And propose or develop procedures to facilitate the harmonization of standards

List of OIE Reference Lab. : http://www.oie.int/eng/oie/organisation/en_listelr.htm 187 OIE Ref. Labs., 36 Countries, 100 Diseases, 30 161 experts,

Twinning (4/12) OIE Reference Laboratories for Rabies (7) Centre of Expertise for Rabies CFIA/ACIA (CANADA) Agence nationale de Sécurité Sanitaire de l'alimentation, de l'environnement et du Travail (Anses) (2) (FRANCE) Institute for Epidemiology, Friedrich-Loeffler Institut (GERMANY) Onderstepoort Veterinary Institute (SOUTH AFRICA) Virology Department, Animal Health and Veterinary Laboratories Agency (UNITED KINGDOM) National Center for Zoonotic, Vector-borne & Enteric Diseases Centers for Disease Control and Prevention (USA)

List of OIE CCs: http://www.oie.int/eng/oie/organisation/en_listecc.htm 35 Collaborating Centres, 20 Countries, 33 Topics, 32 35 experts,

http://www.oie.int/en/support-to-oie-members/laboratory-twinning/

OIE Laboratory Twinning on Rabies (7/12) Germany with Turkey South Africa with Nigeria UK with China

Twinning (8/12) Implementation of diagnostic testing for rabies Validation of in-house diagnostic tests for rabies Participation in proficiency schemes and ring trials for internationally approved diagnostic tests for rabies Epidemiological surveys of rabies in humans and animals Development of oral recombinant vaccines for dogs Evaluation of the vaccination coverage in community-owned dogs Studies of vaccine-elicited immunity in community-owned dogs Assessment of rabies vaccine quality for animal use Source: Veterinary Laboratories Agency

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Conclusions (1/2) The 3 activities described seek to provide examples of short, medium and long term support The PVS by strengthening national veterinary services which can provide a buffer between animal source of the disease and human infection The OIE Rabies Vaccine Bank by piloting/ leveraging vaccination in cooperation with partners Twinning arrangements to enhance the skills and knowledge of scientists and technicians in developing and in transition countries

Conclusions (2/2) OIE activities are global public goods, that is goods whose benefits extend to all countries, people and generations By recognizing the global public good argument and implementing OIE good governance arrangements sustainability of rabies activities can be realized.