Report from the Kennel Club/ British Small Animal Veterinary Association Scientific Committee

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Report from the Kennel Club/ British Small Animal Veterinary Association Scientific Committee Summary results of the Purebred Dog Health Survey for the Newfoundland breed Warning: The results of this survey and particularly the breed-specific analyses should be interpreted with caution. The overall response rate was only 24% with breed-specific response rates from 4.5% to 64.7%.

The Newfoundland breed A total of 89 forms were sent out and 233 were returned, representing 56 live dogs. This breed had a 26.2% response rate (233/89) and it represented 1.7% of all returns (233/13,741). Mortality data A total of 269 deaths were reported and this represents 1.69% of all deaths reported in the survey (269/15,881). The median age at death for the Newfoundland breed was 9 years and 8 months (min = 5 months, max = 15 years and 1 months) and this was lower than the overall median of 11 years and 3 months (Figure 1). Table 1 shows the causes of death for the Newfoundland breed. Age at death is presented for the most common causes of death (Figure 2). Table 1. Causes of death by organ system/category for the Newfoundland breed. Cause of death N % Most common specific causes in descending order 1 Cancer 73 27.1 Osteosarcoma 2 Old age 52 19.3 Old age 3 Cardiac 43 16. Heart failure; cardiomyopathy (dilated, unspecified) 4 Gastrointestinal 18 6.7 Gastric dilatation/volvulus (GDV); pancreatitis; unspecified 5 Combinations 11 4.1 Musculoskeletal; cardiomyopathy; CVA; cancer 6 Musculoskeletal 1 3.7 Arthritis; hip dysplasia; coxofemoral luxation 7 Other 1 3.7 Uncodeable 8 Behaviour 6 2.2 Unspecified problem; aggression 9 Neurologic 6 2.2 Seizures; paralysis; spinal (unspecified) 1 Urologic 6 2.2 Chronic kidney failure; incontinence 11 Cerebral vascular 5 1.9 Stroke or cerebral vascular accident 12 Immune mediated 4 1.5 Unspecified; AIHA and thrombocytopaenia (Evans syndrome) 13 Unknown 4 1.5 14 Hepatic 3 1.1 Liver failure; liver disease unspecified 15 Perioperative 3 1.1 16 Collapse 2.7 17 Poisoning 2.7 18 Reproductive 2.7 Pyometra 19 Respiratory 2.7 Asphyxiation; pneumonia 2 Septicaemia 2.7 21 Endocrine 1.4 Cushings disease 22 Internal bleeding 1.4 23 Pining 1.4 24 Sudden death 1.4 25 Trauma 1.4 Unspecified Total 269 1.

Histogram breed: Newfoundland 5 4 Frequency 3 2 1. 5. 1. Age_at_death 15. 2. Mean =9.184 Std. Dev. =3.41533 N =269 Figure 1. Histogram showing the frequency (as number of dogs) of age at death (in years) for the 269 Newfoundland deaths with age at death reported. breed: Newfoundland 15 12.5 Age_at_death 1 7.5 5 2.5 cancer old age cardiac gastroin combinat the rest Cause_of_death Figure 2. Box and whisker plot of age at death in years for the most common causes of death in the Newfoundland breed (N=269). The dashed line ( ) is the overall median age at death for all dogs in the survey and the dotted line (----) is the overall median age of death for the Newfoundland breed. The solid line within each grey box represents the median age at death from the condition. 3

Morbidity data The median current age of the 56 live dogs with a reported age was 4 years and 9 months (min=2 months, max=14 years and 2 months, Figure 3). Health information was reported for 56 live dogs of which 267 (53%) were healthy and 239 (47%) had at least one reported health condition, resulting in a total of 44 reported conditions with a median of 1 condition/dog (min=1, max=6). The median current age of all healthy dogs with a reported age (N=267) was 3 years and 1 months (min=2 months, max=14 years and 2 months). The distribution of gender and neuter status is shown in Table 2. The median current age of all dogs with one or more disease conditions and a reported age (N=231) was 5 years and 11 months (min=4 months, max=14 years and 1 month). The median age at diagnosis for all disease occurrences with a reported age at diagnosis (N=391) was 2 years and 6 months (min= 1 month, max= 12 years and 3 months, Figure 4). Table 3 shows the disease conditions for the Newfoundland breed. Age at diagnosis is presented for the most common disease conditions (Figure 5). Table 2. Distribution of gender and neuter status for the 51 Newfoundland breed with reported gender and neuter status. Neuter status Gender Intact Neutered Totals Female 17 116 286 (57%) Male 144 71 215 (43%) Totals 314 (63%) 187 (37%) 51 (1%) There was no association between gender and neuter status (P=.843). Histogram 5 BREED: Newfoundland 4 Frequency 3 2 1 2 4 6 8 Curr_Age 1 12 14 Mean =5.4 Std. Dev. =3.211 N =56 Figure 3. Histogram showing frequency of current age in years for the 56 live Newfoundland breed with age reported. 4

Histogram breed: Newfoundland 5 4 Frequency 3 2 1. 2. 4. 6. Age_at_diagnosis 8. 1. 12. Mean =3.2215 Std. Dev. =2.91749 N =231 Figure 4. Histogram showing frequency of age at diagnosis for the 231 Newfoundland breed with one or more disease conditions, using the youngest age at which a disease condition was first reported for those dogs with more than one disease condition or episode. 5

breed: Newfoundland 12. 1. Age_at_diagnosis 8. 6. 4. 2.. musculos dermatol reproduc gastroin ocular cardiac SYSTEM6 immune m urologic respirat the rest Figure 5. Box and whisker plot of age at diagnosis in years for the most common disease conditions in descending order for the Newfoundland breed (N=231 dogs with 391 conditions with age reported). The dashed line ( ) is the overall median age at diagnosis for all dogs in the survey and the dotted line (----) is the overall median age at diagnosis for the Newfoundland breed. The solid line within each grey box represents the median age at diagnosis from the condition.

Table 3. Disease conditions by organ system/category for the Newfoundland breed. All conditions Disease condition N % Most common specific conditions in descending order 1 Musculoskeletal 11 25. CLR; CHD; arthritis (hips=unspec>elbows>forelimb>rest); OCD (elbow=shoulder=unspec) 2 Dermatologic 61 15.1 Pyotraumatic dermatitis; dermatitis; alopecia; mites (cheyletiella>sarcoptes) 3 Reproductive 45 11.1 False pregnancy; pyometra; infertility; vaginitis 4 Gastrointestinal 27 6.7 Gastric dilatation/volvulus; diarrhoea; colitis; EPI; pancreatitis 5 Ocular 27 6.7 Entropion; KCS; cataracts; red eye 6 Cardiac 26 6.4 Heart murmur (unspec>grade 1,2>grade 3); cardiomyopathy (dilated>unspec); aortic stenosis 7 Immune mediated 24 5.9 Atopy; dust mite allergy; allergy other (unspecified); food allergy 8 Urologic 21 5.2 Cystitis; incontinence (unspecified>after spay); cystinuria; kidney disease other (unspec) 9 Aural 2 5. Otitis externa; aural haematoma; otitis media 1 Respiratory 17 4.2 Kennel cough; pneumonia; laryngeal paralysis 11 Unknown 9 2.2 12 Cancer 7 1.7 Unspecified; carcinoma (toe); lymphoma; plasma cell tumour (lip) 13 Trauma 7 1.7 Musculoskeletal (forelimb>hindlimb=hind paw); neurologic (nerve); other (unspecified) 14 Neurologic 5 1.2 IVDD (lumbar); deafness; meningitis; seizures 15 Benign neoplasia 4 1. Lipoma 16 Endocrine 2.5 Cushings disease; diabetes mellitus 17 Dental 1.2 Defect other than extra teeth Total 44 1.