Your sheep health is your wealth

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Your sheep health is your wealth Matt Playford, Dawbuts Pty Ltd, Camden NSW PLEASE INSERT LOGO HERE 1

Cost of endemic diseases Lane (2015) MLA WORMS $436m Key point is that we are still not spending enough on worms i.e. cost of treatment far outweighed by cost of loss production. 2

Cost of worms in sheep 1. Weight gain- decreased by 15% on average (adjusted) 1. Raw figure 23% decrease 2. Single species- Haemonchus 21%, Teladorsagia 19%, Trichostrongylus 22% 3. Mixed species infection- 26% decrease 2. Wool growth- decreased by 10% on average 3. Lactation- decreased by 22% on average Source: Mavrot et al. (2015) Meta analysis, Parasites & Vectors 8:557 3

Stages L1 L2 in faecal pat, while L3 migrates to soil or pasture and remains there until either it dies or is eaten 4

1. Haemonchus- barbers pole worm Live in the abomasum, feed on the blood Summer rainfall barbers pole appearance Lay up to 10,000 eggs/day 5

2. Black scour worm-trichostrongylus Lives in small intestine Causes damage to villi Appetite loss Malabsorption Scours Photos courtesy of Ian Beveridge, (WormBoss) 6

3. Small brown stomach worm-teladorsagia Lives in the abomasum Small in size (8-12mm) Female can lay 200 eggs per day Capable of living in a state of hypobiosis 7

Parasite-Induced Anorexia Corticosteroid treatment on lambs infected with 4000 T. circumcincta d -1 at day 42 P.I. (Greer et al 2008 IJP 38, 1717-1728) Infected FEC 300epg VFI 0.45 kgdm/d DG 86g/d No. of worms = 9,000 Infected/Immunosuppressed FEC 4000epg VFI 2.20 kgdm/d DG 400g/d No. of worms = 40,000 8

Rise of worm egg output in single and multiple-bearing ewes 1000 500 9

Dry ewes, singles and twinners 1. Dry ewes should be monitored and may not need drenching TIP!- Run untreated dry ewes with lambs to increase refugia and decrease worm resistance 2. Single ewes pre-lambing drench if required 3. Twin-bearing ewes- pre-lambing drench (LA?) + feed supplements 10

Anthelmintics 1960-2017 2012 Derquantel + Abamectin Until now there have only been three broad spectrum anthelmintic classes: the BZ or whites, levamisole or clear and macrocyclic lactone or ML s. In the graph above each class is represented by a different colour. All actives within a class work in exactly the same way i.e. they have the same mode of action. That means when resistance develops to one active within a class the others will follow. This is what is known as side resistance. As you can see that the last new class of anthelmintic was launched in 1981 (globally) with the active ivermectin (Ivomec). The long delay shows two things: how difficult it is to get a new anthelmintic class to market and how important it is to make the best possible use of this long awaited opportunity. 11

Efficacy of drenches against common worms of sheep 12 12

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1. Use effective drenches- (>95% efficacy) 2. Use combination drenches in preference to single active drenches and short instead of long-acting drenches. 3. Monitor worm egg counts and drench when necessary 4. Use non-chemical means of worm control such as paddock spelling, rotation, alternating with cattle, making hay 5. Feed sheep for resilience and select sheep for resistance 6. Rotate active ingredients (drench groups) 14

Sheep lice- Bovicola ovis Adults tiger stripes Nymphs small & pale Nits (eggs) white, attached to wool fibres Source: WA Ag 15

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Primary striker blowfly The primary striker 90% of flystrike in Australia Maggots 1mm, grow to 13mm 18

Secondary strikers 19

Flyboss tools- predict flystrike risk 20

Chemical Group Effect Duration Comment Cyromazine IGR Pyrimidine Stops larval development Fly only Long acting Spray on or jetting Dicyclanil IGR Pyrimidine Stops larval development Fly only Ultra Long acting Spray on Diflubenzuron/ Triflumuron IGR Diphenylurea Stops larval development Long acting Dip, Pour On or jetting Diazinon OP Organophosphate Blocks acetyl choline esterase Short acting Spot, spray on (or dip) Ivermectin Macrocyclic Lactones Knockdown Long acting Jetting Spinosad Spinosyns Knockdown Short acting Dip, jetting Alphacypermethrin SP Synthetic Pyrethroids Knockdown Mediumacting Spray on long wool 21

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WEC RANGE ACROSS A MOB OF 636 RAMS This slide shows Dawbuts data for 636 rams run together on one property and all tested on the same day. Illustrates the wide variation of WECs and susceptibility to worms within one flock. 23

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Analgesics 25 25

Biosecurity Biosecurity Plan Sheep Health Statement Market Assurance Plan Ovine brucellosis-free Accredited Studs 1.Lice 2.Footrot 3.Ovine Johne s disease 4.Worms 5.Brucellosis 26 26

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Quarantine drench Zolvix Plus + Combi OR Startect + Combi 4 active ingredients including at least ONE of the new drenches (monepantel and derquantel) 28 28

Footrot 29 29

Take home messages 1. Get animal health right our industry s future relies on farmers taking care of animal health and welfare issues. 2. Worms cost each Australian sheep farmer about $28,000/year (based on average figures) mainly by slowing growth rates and depressing wool, lactation and reproductive performance. 3. Check for lice by restraining sheep with deranged wool, do 20 partings per side, treat all sheep with an effective chemical applied meticulously. 4. Talk to your vet about appropriate analgesic usethis includes for mulesing and lambmarking, as well as for other surgical procedures 5. Have a written biosecurity plan and check it regularly 6. Monitor each ewe mob s body condition score (BCS) at least 4 times per year, draft on BCS not age, and feed to maintain ideal score. 7. Vaccinate all lambs twice (at marking and weaning) and do annual vaccination of ewes to ensure protection from the common deadly diseases. 30 30

Best practice indicators 1. Only use effective drenches- (>95% efficacy). Test drenches to check their efficacy. 2. Use combination drenches in preference to single active drenches and short instead of long-acting drenches. 3. Monitor worm egg counts and drench when necessary test every mob at least every two months 4. Use non-chemical means of worm control such as paddock spelling, rotation, alternating with cattle, making hay 5. Feed sheep for resilience and select sheep for resistance- using ASBV for WEC when choosing rams 6. Rotate active ingredients (drench groups) 7. Know the health risk of introduced stock including drench resistance status,ojd, vaccination status, lice and footrot status 8. Do ram inspections each year 12 weeks before joining date- cull rams with lumps in their reproductive organs and get your vet to blood test rams for brucellosis. 31 31