Table 2 - Medications and their ideal route of administration Pharmacologic-Therapeutic Classification Drug Route Antihistamines First-Generation Antihistamines Diphenhydramine Promethazine Anti-infective Antibiotics Aminoglycosides Amikacin sulfate Gentamicin sulfate Streptomycin Tobramycin into large muscle mass Cephalosporins Cefazolin sodium Cefepime HCl Cefotaxime sodium Ceftazidime pentahydrate Ceftriaxone sodium Cefuroxime sodium into large muscle mass Carbapenems Imipenem Penicillins Ampicillin Cloxacillin Penicillin Piperacillin Anti-infectives Bacitracin Clindamycin Antineoplastic Methotrexate or Intraarterial Autonomic Parasympathomimetic Neostigmine Phenylephrine HCl or Parasympatholytic Antispasmodics Atropine, or Intra-osseous Sympathomimetic Selective Beta- Isoproterenol HCl or
(Adrenergic) adrenergic Alpha- and Beta- Adrenergic Ephedrine Epinephrine or (preferred) or Glycopyrrolate Scopolamine or Sympatholytic Non-Selective Alpha-Adrenergic Blocking Phentolamine mesylate Skeletal Muscle Relaxants Succinylcholine chloride Blood Formation and Coagulation Antianemia Iron Preparations Iron Coagulants and Anticoagulants Anticoagulants Dalteparin Enoxaparin Heparin Hematopoietic Darbepoetin alfa Epoetin alfa Filgrastim Cardiovascular Cardiac Anti-arrhythmics Lidocaine HCl Intra-articular Procainamide HCl Cardiotonic Digoxin Central Nervous System Analgesics and Antipyretics Non-steroidal Anti-inflammatory Ketorolac Slowly via deep injection Opiate Codeine or Opiate Partial Fentanyl citrate Hydromorphone Meperidine Morphine Nalbuphine Naloxone HCl or or or or or
Pentazocine or Anticonvulsants Barbiturates Phenobarbital Psychotherapeutic Antipsychotics Chlorpromazine Flupentixol Fluphenazine Haloperidol Loxapine Methotrimeprazine Olanzapine Risperidone (gluteal or deltoid) Anxiolytics, Sedatives, Hypnotics Benzodiazepines Diazepam Lorazepam Midazolam Miscellaneous Hydroxyzine Antimigraine Selective Serotonin Sumatriptan Anticholinergic Benztropine mesylate Electrolytic, Caloric, and Water Balance Respiratory Tract Gastrointestinal Diuretics Furosemide Miscellaneous Omalizumab Antiemetics Antihistamines Dimenhydrinate Prochlorperazine 5-HT3 Receptor Antisecretory Histamine H2- Ondansetron Ranitidine Prokinetic Metoclopamide or Hormones and Synthetic Substitutes Androgens Androgen Receptor Cyproterone acetate
Adrenals Betamethasone, intraarticular, intra-lesional, local or soft tissue Dexamethasone Hydrocortisone Methylprednisolone Triamcinolone, intralesional or soft tissue Intra-articular, intra-lesional,, Intrasynovial or soft tissue Intra-articular, intra-bursal or Androgens Testosterone Estrogens Estrogens, conjugated Antidiabetic Insulins Antihypoglycemic Glycogenolytic Glucagon or Pituitary Desmopressin or Vasopressin or Somatotropin Somatropin (pen may be or ) Progestins Medroxyprogesterone Oxytocics Progesterone Carboprost tromethamine Oxytocin Vitamins Vitamin B Complex Cyanocobalamin or deep (avoid dermis and upper sc) Folic Acid Pyridoxine or or
Thiamine Vitamin C Ascorbic Acid or Vitamin K Activity Vitamin K or Miscellaneous Therapeutic Antidotes Leucovorin Disease-modifying Antirheumatic Abatacept Adalimumab Anakinra Etanercept Gold Sodium Thiomalate (preferably gluteal)