Ireland 2014 Eradication Programme for Bovine Tuberculosis Standing Committee on Plants, Animals, Food and Feed. May 2015

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Department of Agriculture, Food and the Marine Ireland 2014 Eradication Programme for Bovine Tuberculosis Standing Committee on Plants, Animals, Food and Feed May 2015

Introduction The eradication programme for Bovine TB for 2014 was implemented effectively; 98.63% herds tested (balance no stock when test scheduled or new herds not yet with stock) Significant reduction in incidence of Bovine TB in 2014 compared with 2008: Number of reactors down from 29,901 in 2008 to 16,145 in 2014 i.e. (45% reduction) 5.88% - 3.88% reduction in Herd Incidence (38% reduction) 3.25-1.91 reduction in APT (41% reduction)

Ireland - Demographics December 2014 116,976 holdings with bovines (114,508 = 97.89% OTF and 96% herds OTF in excess of 1 year) 6.1m animal population December (6.8m June) Population peaks post Spring calving prior to Autumn slaughter approx. 2.3 million cows (50% dairy cows) Approx. 83,000 breeding herds (20% dairy herds) Average herd size: 53

Mountains are red Farmland is purple Forests are green Approximately 91% (3.82 million ha) of agricultural area is devoted to grass (silage, hay and pasture, rough grazing) Pastureland dominates with hedgerows between fields Highest mountain is 1,038 m Longest river 386 km Ireland has a mild but changeable oceanic climate with few extremes

cattle density map 2013 cattle and badgers share and feed on the same grassland areas

2014 TB Programme main measures Disease detection: Annual herd screening test Single Intra-dermal Comparative Tuberculin Test (SICTT) Routine veterinary post-mortem slaughterhouse surveillance Additional targeted risk-based testing on an epidemiological basis e.g. check tests on herds contiguous to infective breakdown, TB history etc.

2014 TB Programme contd. Post Disease detection Holding and movement restrictions (OTF status suspended/withdrawn as per Directive) on suspect & positive animals/herds Gamma-interferon assay in infected/problem herds Epidemiological investigations to include field visits, as necessary, on infective breakdowns Wildlife control in infected areas (targeted badger removal under license where badgers implicated) Depopulation (stamping out) of heavily infected herds Farm hygiene disinfection of premises Compensation for removal of reactors

2014 TB Programme main measures contd. Status restored after clear tests at 60 days & 4 months Herd check tests at 6, 12 & 18 months Standard inconclusive reactors (in otherwise clear herds) confined to herd of disclosure for life even after passing retest. Badger population control measures maintained pending availability of effective and licensed TBvaccine

2014 TB Programme contd. QC of SICTT supervision and monitoring of performance of testing veterinarian tuberculin assay on naturally infected bovines Computerised database AHCS & AIM (linked) links disease test recording and identification & movement databases (ensures testing of all animals) Electronic communication with veterinarians Animal movements control at marts, assembly centres, between farms and at slaughter Display of animal test data on AHCS at marts and assembly centers

Research CVERA Centre for Veterinary Epidemiology and Risk Analysis staff from Department of Agriculture and Food, Veterinary Faculty of University College Dublin and Teagasc (Irish Agriculture and Food Development Authority). Covers major areas of interest. Wildlife Unit undertakes badger population controls and investigates the role of the badger in the spread of bovine tuberculosis Badger Vaccine Development Project in collaboration with UK and France Diagnostics UCD (interferon-γ Assay), - CVRL (histology, culture, strain typing, ELISA)

Interferon-γ assay in infected/problem herds GIF 2013 GIF 2014 Total Samples submitted 14,621 Total Samples submitted 19,405 Total Positive 8,637 Total Positive 10,259 25,000 samples targeted in 2015 (earlier & more)

Main TB trends 2008-2014 Herd Incidence 5.88% in 2008-3.64% in 2014 (34% reduction) Herd Incidence Herd Incidence 8,00 6,00 4,00 2,00 0,00 2008 2009 2010 2011 2012 2013 2014 8.000 6.000 4.000 2.000 0 Herds Restricted 2008 2014.

Main TB trends 2008-2014 Number of reactors 29,901 in 2008 16,145 in 2014 (41% reduction) Number of Animals Reactor 5 years 25.000 20.000 15.000 10.000 Number of Animals Reactor Expon. (Number of Animals Reactor) 5.000 0 2010 2011 2012 2013 2014

Main TB trends 2008-2014 APT Reactors per 1,000 tested. 3.25 in 2008-1.91 in 2014 (41% reduction) 4,00 Reactors per 1,000 tests Reactors per 1,000 tests 3,00 2,00 1,00 0,00 1 2 3 4 5 6 7

Ongoing Continuous monitor of programme performance Integration of data/research evaluations together with routine system and performance reviews leading to Constant update and enhancement of herd and animal level controls in an integrated and targeted manner

Evaluation of Ongoing contribution of shortfall in test specificity (<100%) to reduction in positive predictive value of test as true disease levels decline Contribution of false positives to apparent herd incidence (based solely on SICTT test positives) and impact of these on ability to achieve a pre-specified target reduction as set by Commission

The Future Badger removal programme (despite limitations applicable to a protected species) as addition to normal measures appears to be paying dividends. Continue to implement programme on similar lines including badger removal to control badgerpopulation density Research into Badger vaccination is on-going (in collaboration with UK) but definitive conclusions as to efficacy in wild population will not be available until mid 2015 at the earliest. Sustained progress towards ultimate eradication of bovine TB is dependent on effective and sustained control of disease in the sympatric infected wildlife (badger) and cattle populations

Department of Agriculture, Food and the Marine Thank you for your attention