AFRICAN NATURAL PRODUCTS RESEARCH AND TRAINING NETWORK (AFNNET)

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1 University of Nairobi (UoN) Makerere University (MAK) Sokoine University of Agriculture (SUA) AFRICAN NATURAL PRODUCTS RESEARCH AND TRAINING NETWORK (AFNNET) SOKOINE UNIVERSITY OF AGRICULRE

AFNNET PARTNERS 2 Makerere University (MAK) Prof. David John Kabasa Dr. Samuel Okello Sokoine University of Agriculture (SUA) Tanzania Prof. Robinson Hammerthon Mdegela University of Nairobi (UoN), Kenya Dr Stephen Gitahi Kiama

Project implementation team at SUA (Staff) 3 Prof. Robinson Mdegela Node Coordinator and Supervisor Prof. Madundo Mtambo Assistant Node Coordinator and Supervisor Prof. Lesakit Mellau - supervisor Prof. Resto Mosha Supervisor Prof. Elioth Phiri Supervisor Dr. Robert Max Supervisor Dr. Joseph Magadula - Supervisor

Project implementation team at SUA (Students) 4 PhD students Ms. Faith Mabiki (F) Dr. Gaymary Bakari (F) MSc students Ms. Skitu Saimon (F) Mr. Jangson Ngabo (M) Mr. Masunga Mabula (M)

Project specific objectives 5 Upgrade existing MSc-level junior academic staff to PhD-level Natural Products (NP) scientists Participate in development and piloting of a nonterminal regional Masters curriculum in Natural Products Technologies and Value chain management Engage more the government and the local NP industry in the actions of the AFNNET

6 Increase availability of research opportunities for academic staff and students Increase the number and quality of women scientists with MSc- and PhD-level training in Natural Products Enhance staff retention at universities in the region

Training of PhD studens 7 Recruitment of PhD Students 2 female PhD candidates Employee of SUA Faculty of Science Faculty of Veterinary Medicine Both, at Final stage of data collection Expect to submit thesis for examination by March 2012

Research titles 8 Faith Mabiki (F) (Tanzania) Potential Bioactivity of Extracts and Compounds from Synadenium glaucescens Pax. (Euphorbiaceae) Gaymary Bakari (F) - Tanzania Anthelmintic and Antimicrobial Activities of Commiphora Swynnertonii in Local Chickens

Training of MSc students 9 Recruitment of MSc Students 1 female MSc candidate 2 male MSc candidates Employee of SUA & District Councils 2 are at final stage of data collection Will submit dissertation for examination by September 2011 1still challenged with methods development, though now with promising results Expected date to submit thesis for examination -????

MSc Research Titles 10 Name Ms. Sikitu Simon Title Assessment of Nutritive Value of Commiphora swynnertonii and its Effectiveness in Lowering Serum Cholesterol Levels Mr. Jangson Ngabo Identification and Authentification of Synadenium glaucescens as Herbal Medicinal Plant by DNA Profiling Mr. Masunga Mabula Assessment and Characterization of Food Types Consumed by Wahadzabe Nomads in Karatu and Meatu Districts, Northern Tanzania

Additional MSc student 11 Name Christa Mwageni Title Effect of Crude Root Extracts From Synadenium glaucescens on Selected Bacterial Infections in Albino Mice

Special Projects 12 S. No Name Title 1 Angela M The anti microbial activity of crude extract of Synadenium glaucescens 2 Jackson M Determination of the biological activity of the fractions of the root bark of Synadenium species 3 Mlowe F The use of Synadenium glaucescens extract in the control of porcine cysticercosis 4 Mwesongo J Assessment of antimicrobial activity of Synadenium glaucescens crude extracts on Mycobacterium tuberculosis strains 5 Frank, R Isolation and identification compounds from dichloromethane extract of Synadenium glaucescens 6 Martin, J Antimicrobial activity of traditionally prepared extracts of Synadenium glaucescens

Special projects 13 S.No Name Title 7 Jumanne, Saad Effect of Commiphora swynnertonii against Mycobacterium tuberculosis 8 Mumbi, Zemba The efficacy of Commiphora swynnertonii on surgical wound healing using guinea pigs as model animals 9 Anyisile, Israel Effect of ethanolic extract of Commiphora swynnertonii on markers of liver function in experimental rats 10 Thomas, Jackson Assessment of antimicrobial activity of Commiphora swynnertonii using in vitro bioassay 11 Ushile, Kulwa Effects of Commiphora swynnertonii on plasma protein and energy metabolism in experimental rabbits 12 Albert, Hosea Effects of Commiphora swynnertonii on some markers of kidney function in experimental rabbits 13 Haidary, Zaina Effects of Commiphora swynnertonii on some hematological indices in experimental rabbits

Special Projects 14 S. No Name Title 14 Mbunde Maurice Assessment of Medicinal Use of Wild Animals in Villages Adjacent to Serengeti National Park

Strategic research support 15 S. No Name Strategic research topic 1 Msalilwa Lufingo Fasciolosis treatment trials in goats using medicinal plants, Embelia schimperi and Albizia antihelmintica

Regional MSc in Natural Products Technologies & Value Additions 16 Approved by SENATE of the University Call for applications, June 2011 MSc Students Support from the project Support from outside the project Admission and registration in September 2011

PROGRAMME STRUCTURE AND COURSE DESCRIPTION Course Code Course Title Lecture hours Practical hrs Seminar hours Total hours Credits NPV 661 NPV 665 NPV 666 NPV 667 VM 622 NPV 700 Introduction to natural products science 30 20 10 60 1.5 Bio-prospecting and value addition 30 30 0 60 1.5 Natural Products efficacy and safety 30 20 10 60 1.5 Research methods and communication 30 20 10 60 1.5 Statistics and data management 30 45 15 90 2.0 Dissertation TOTAL 150 145 35 330 8 17

Specialty core courses Course Code Course Title Lecture Practical Seminar Total hours Credits Specialty core course in Environmental Natural products NPV 662 Natural Products and the Environment 30 30 0 60 1.5 NPV 663 NPV 664 Application of analytical techniques for Natural products Natural products and biological systems interactions Specialty core course in Analytical techniques Specialty core course in Pathobiology 45 30 0 75 2.0 30 30 0 60 1.5 Specialty core course in entrepreneurship NPV 668 Natural products entrepreneurship 30 30 30 90 2.0 18

Elective courses Course Code Course Title Lecture Practical Seminar Total hours Credits NPV 660 Pharmacognosy 30 20 10 60 1.5 NPV 669 Natural products policy, Gender and Ethics NPV 670 Propagation and cultivation of Medicinal plants NPV 671 Natural products in food technology and agro-industries NPV 672 Natural products biotechnology, bioinformatics and safety 30 15 15 60 1.5 30 20 10 60 1.5 30 20 10 60 1.5 30 20 10 60 1.5 MVPT 605 Ethnopharmacology 30 20 10 60 1.5 FP 604 Sustainable Use of Non-Wood Forest 30 20 10 60 1.5 Products (NWFPs) 19 TOTAL 210 135 75 420 10.5

Research capacity development 20 Human resource Infrastructure Refurbishment of Natural Products Laboratory Support for CR-AFNNET & other sources

Output 21 Training PhD, MSc, SP Developed MSc in Natural Products Technologies and Value Additions Laboratory Networks & networking 4 patents 7 manuscripts submitted by October 2011

Impact/outcome 22 Effective compounds/extracts Antiviral, antibacterial &antifungal Metabolic conditions Cholesterol Haematology & blood chemistry Liver and kidney etc Confirmed nutritive value and safety of different natural foods High demand for training in NP at various levels High demand for use of the established NP laboratory Sensitized stakeholders

The way forward 23 Training of PhD and MSc candidates Already advertised PhD positions, awaiting for scholarships award Solicit more funding opportunities Space Staff offices Student offices Conference room/class room Laboratory Transport

Collaborators and partners Acknowledgements 24 Carnegie SIG IAS RISE Management of Universities SUA, UoN, MK AFNNET secretariat Director Project manager All node coordinators Mentors, supervisors

Thank you for listening