D edicated to m y late fath er G.Y. Somayajulu Garu
Veterinary Pathology SEVENTH EDITION Parti : GENERAL PATHOLOGY Part II : SPECIAL PATHOLOGY Part III : INFECTIOUS DISEASE Ganti A. Sastry G.M.V.C., B.V.Sc., M.Sc., M.S., Ph.D. (Kansas) Retired Principal & Professor of Pathology, College of Veterinary Science, Tirupati - 517 502 Revised & Enlarged by P. Rama Rao M.V.Sc., F.R.V.C.S. (Sweden), Ph.D. Principal, Andhra Pradesh Agricultural University, College of Veterinary Science, Tirupati - 517 502 CBS CBS Publishers & Distributors Pvt. Ltd. New Delhi Bengaluru Chennai Kochi Kolkata Mumbai Hyderabad Nagpur Patna Pune Vijayawada
ISBN: 81-239-0738-9 First Edition: 1968 Second Edition: 1969 Third Edition: 1971 Fourth Edition: 1975 Fifth Edition: 1979 Sixth Edition: 1983 Seventh Edition: 2001 Reprint: 2002, 2003, 2004, 2005, 2006, 2007, 2008, 2009, 2010, 2011, 2012, 2013, 2014, 2016 Copyright Authors & Publisher All rights reserved. No part of this book may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopying, recording, or any information storage and retrieval system without permission, in writing, from the publisher. Published by: Satish Kumar Jain for CBS Publishers & Distributors Pvt. Ltd., 4819/XI Prahlad Street, 24 Ansari Road, Daryaganj, New Delhi - 110002 delhi@cbspd.com, cbspubs@airtelmail.in www.cbspd.com Ph.: 23289259, 23266861,23266867 Fax:011-23243014 Corporate Office: 204 FIE, Industrial Area. Patparganj, Delhi - 110 092 Ph: 49344934* Fax:011-49344935 E-mail: publishing@cbspd.com publicity@cbspd.com Branches: Bengaluru: 2975, 17th Cross, K.R. Road, Bansankari 2nd Stage, Bengaluru-70 Ph:+91-80-26771678/79 Fax:+91-80-26771680 E-mail: cbsbng@gmail.com, bangalore@cbspd.com Chennai: No. 7, Subbaraya Street, Shenoy Nagar, Chennai - 600030 Ph: +91-44-26681266,26680620 Fax:+91-44-42032115 E-mail: chennai@cbspd.com Kochi: Ashana House, 39/1904, A.M. Thomas Road, Valanjambalam, Emakulum, Kochi Ph: +91-484-4059061-65 Fax: +91-484-4059065 E-mail: cochin@cbspd.com Kolkata: 6-B, Ground Floor. Rameshwar Shaw Road, Kolkata - 700014 Ph:+91-33-22891126/7/8 E-mail: kolkata@cbspd.com Mumbai: 83-C, Dr. E. Moses Road, Worli, Mumbai - 400018 Ph:+91-9833017933, 022-24902340/41 E-mail: mumbai@cbspd.com Representatives: Hyderabad: 0-9885175004 Nagpur: 0-9021734563 Patna: 0-9334159340 Pune: 0-9623451994 Vijayawada: 0-9000660880 Printed at'. J.S. Offset Printers, Delhi
PREFACE FOR THE SEVENTH EDITION In an effort to update the informations on poultry diseases according to VCI syllabus and needs of poultry industry. Dr. P. Rama Rao, Dr. Gopal Yadgirkar and Dr. S. Rafeeque Ahmed former staff members of the Department of Pathology in the faculty of Veterinary Science, Acharya NG Ranga Agricultural University have revised the book. The information is compiled from the following books beside incorporating the experiences and observations of above authors. 1. Diseases of Poultry, edt. B.W. Calnek and associates, Affiliated East West Press, Iowa State University Press, 9th edition, 1994. 2. Poultry Diseases, FTW Jordan, English Language Book Society, Bailliere Tindall, 3rd edition, 1990. DR. P. RAMA RAO
PREFACE Continued demand for my book by the student body had necessitated the production of this Sixth eiition. It is no little satisfaction to the author to find that hit book is felt needed and is found useful by most of the Veterinary students of the country. In this edition some parts are revised and many facts and conditions have been added to bring the contents of the book uptodate. As such the number of pages had to bi increase 1. To mik^ the information mon: authentic. I have made a departure in this edition, by requesting Professors of other colleges as well as some of our own college, to subscribe chapters or conditions in which they have specialised. By this moans the students get benefitted by the experience and expertise of these Professors. I am grateful for the following persons for contributing on the subjects noted against their names to this part : Dr. D. Anjaneya Prasad Dr. P. Babu Rao Dr. B. Sambamurthy Bovine Kctosis and revision of chapter on Disturbances in Mineral Metabolism. Ionizing radiation. Viruses and Tumorigenesis. Dr. K Sathyanarayana Rao Electron Microscopic of normal cell. Dr. A. Sreerama Murthy Dr. D. Sunderasiva Rao Dr. J.L. Vegad structure and function Hereditary defccts and disease resistance. Revision of chapter on Neoplasms. Chapters on Inflammation and Healing. Acknowledgement of contribution of others will be made in the subsequent parts. I am grateful to Dr. P. Rama Rao, Head and the staff of the Department cf Pathology of this college, for their help in the production of this edition. I am indebted to the following Professors of Veterinary Pathology for prescribing my book in their colleges and rendering me advice and help whenever soght for : Dr. S. Domodaran and Dr. P. Ramakrishnan of Madras ; Dr. M. Krishnan Nair and Dr. A. Rajan of Kerala ; Dr. S.J. Seshadri of Bangalore ; Dr. S.S. Bhagwat of Nagpur ; Dr. B.C. Nayak of Bhubaneswar ; Dr. S.N. Nandi of Calcutta ; Dr. S. Kwatra, formerly of Assam; Dr. J.L. Vegad of Jabalpur ; Dr. U R.K. Rao. of Mhow ; Dr. P.K Ramachandran and Dr. N.S. Parihar of IVRI, lzaftngar; Dr. P.N. Mchrotra and Dr. P.'L. Arya of Bikaner; Dr. S.M. Ajinkya of Bombay ; Dr. D.N. Kalra of Hissar ; Dr. Balwant Singh of Ludhiana; Dr. B. Deshpande of Parbhani ; Dr. J.M. Dwivedi of Mathura ; Dr. D.D. Heranjal of Anand and Dr. M. Mahender of Hyderabad. ^ It is the fond hope of the author that this book will continue to be useful to the Veterinary Students and that it will help lay a sound foundation in the better and rational understanding of disease processes, GANTI A. SA STR
CONTRIBUTORS Part I Dr. D. Anjancya I rasad, BVSC, MVSC, PhD (Kansas) Professor of Animal Scienccs, College of Veterinary Science, Tirupati (A. P.) Dr. P. B.ibu Rao, MSC, PhD, Lecturer in Physics, S.V. College of Arts and Science, Tirupati (AP.) Dr. B Sunbamurthy, GMVC, 15VSC, MS, (Kansas) Retired Associate Piofessor of Microbiology, College of Veterinary Scicnce, Tirupati (A.P.) Dr. K. S.ithyannrayana Rao, GMVC, BVSC, MS, (Kansas) Principal & Professor of Physiology, College of Veterinary Scicnce, T irupati (A. P.) Dr. A. Srerramamurthy, BVSC, MSC (Vet), PhD, Head, Department of Animal Genetics and Breeding, College of Veterinary Science, Tirupati. Dr. D. Sunderasiva Reo, M D. Retired Principal and Professor of Pathology, Rangaraya Medical College. Kakinada, A P. Now Pathologist, Amala Cancrr Hospital and Research Institute, Puzhakkal, Kerala. Dr. J.L. Vegad. BVSC, ASSOC, IVRI ; PhD. (New Zealand). University Professor and Head, Department of Pathology, College of Veterinary Science & AH. Jabalpur, M.P. P a rt II Dr. M.S. Kwatra, MVSC, PhD. Senior Veterinary Investigation Officer, College of Veterinary Science, Ludhiana. (Mulberry Heart Disease and Manchester wasting Disease of cattle). Dr. B B. Mallick, D.S.C. (Sarborne) ; FCAI., Assoc IVRI, BSC, GVSC (Hons) Head, Division of Virology, IVRI, Mukteswar. (Immunological Diseases). Dr. A. Rajan, BVSC, MVSC, PhD. Piofessor of Pathology, College of Veterinary Science, (PO) Mannuthy. Trichur, Kerala. (Revision of Endocrine Glands ). Dr.-P. Rama Rao, BVSC, MVSC, 1RVCS (Sweden) PhD. Head, Department of Pathology, College of Veterinary Science, Tirupathi. (Revision of The Reproductive System ). Dr. J.L. Vcgad. BVSC, Assoc. IVRI, PhD (New Zealand). University Professor and Head, Department of Pathology, College of Veterinary Science, i AH, Jabalpur (The Nervous System).
The autor is greatly indebted to Part Id Dr. T.N. Ghosh, PhD, Professor of Protozoology, Calcutta School of Tropical Medicine. Calcutta, for his note on Toxoplasmosis, Dr. D.S. Kalra PhD., Professor & Head Department of Pathology, Veterinary College, Hissar, for the Chapter on Diseases caused by Fungi, Dr. S. Krishnaswamy MVSC, DVPH, & FH (Den), PhD, Professor and Head Department of Microbiology, College of Veterinary Science, Tirupathi, for reviewing chapters ou Diseases caused by Bacteria, Viruses and Rickettsia.. Dr. M. S. Kwatra, MVSC, PhD, Senior Veterinary Investigation Officer, College of Veterinary Science, Ludhiana, for contributing on Dcgnalla Disease, Dr S J. Sesliadri, MVSC, Professor & Head. Department of Pathology Bangalore Veterinary College for his contribution 011 Bacterial and Viral Diseases of Poultry, Dr. S. R. G. Muralidharam, BVSC, MVSC, PhD, Assistant Professor of P a r a s ito lo g y, C o lle g e of Veterinary Science, Tirupathi, for reviewing chapters on Diseases caused by Helminths and Insects and iheir larvae., Dr. A. Venkataratnam, GMVC, BVSC, DAP, MSC (L pool) Associate Professor of Parasitology, College of Veterinary Science, Tirupathi, for reviewing chapter on Diseases caused by Protozoa.,
CONTENTS Chapter Page PART I GENERAL PATHOLOGY 1. Introduction 1 2. Etiology 3. Degenerative Processes 13 4 Inflammation 48 5. Healing 68 tj. Disturbances of growth 78 7. Circulatory Disturbances 84 8. Physical and Chemical Injuries 114 9. Disturbances of Mineral Mi tabolism '38 10. Deficiency Diseases 15."> 11. Disorderr of Pigment Metabolism 174 12. Genetics.'iid Disease 185 13 Neoplasm; ^02 PART II SPECIAL PATHOLOGY 14 The Cardiovascular System ^' 7 15. The Hemopietic System 16. The Respiratory System 315 17. The Digestive System 237 18. The Urinary System 377 19. Tho Nervous System 400 20. Tbe Reproductive 421 2 1. T he Musculoskeletal System 462 11. The Endocrine Glands 485 2.1. T he Skin and its Appenda^.,
The Eye and Ear Immunological Diseases 520 535 PART III INFECTIOUS DISEASE Diseases Caused by Bacteria Diseases Caused by Viruess Diseases C a ; d by Kungi l)isi ases Caused by Rickettsia Diseases Caused by Protozoa Diseases Caused by Helminths Diseases Caused by Insects & their Larvae Inde* 543 620 669 685 61'3 714 747 7^8
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