Liofilchem Chromatic Chromogenic culture media for microbial identification and for the screening of antimicrobial resistance mechanisms

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Liofilchem Chromatic Chromogenic culture media for microbial identification and for the screening of antimicrobial resistance mechanisms Microbiology Products since 1983

Liofilchem Chromatic ESBL Selective chromogenic medium for screening Gramnegative ESBL-producing bacteria. ESBL (Extended Spectrum β-lactamases) are enzymes that confer resistance to penicillins, extended-spectrum third generation cephalosporins (C3G) and monobactams. The ESBL-producing Enterobacteriaceae are responsible of severe hospital-acquired infections. The correct and early detection of ESBL-producing microorganisms is critical for addressing to the most appropriate antimicrobial therapy and avoiding the spread of infections. Chromatic ESBL medium contains a mixture of chromogenic compounds and antibiotics that allow the the growth of ESBLproducing bacteria while inhibit the other bacteria, including the ampc-positive. While the AmpC-positive bacteria can still be treated with certain beta-lactamase-stable antibiotics, the presence of an ESBL infection seriously limits treatment options because of the wide resistance acquired. Chromatic ESBL 11622 Escherichia coli DSM 22311 Chromatic ESBL+AmpC 11629 Chromatic ESBL 500 g 610629 Chromatic ESBL 100 g 620629 Chromatic ESBL supplement 81089 Chromatic ESBL+AmpC supplement 81090 Liofilchem Chromatic CRE Screening medium for the detection of Carbapenem- Resistant Enterobacteriaceae. Chromatic CRE contains a mixture of carbapenems for screening a wide variety of carbapenem-resistance mechanisms and provides presumptive identification of E. coli and the Klebsiella, Enterobacter, Serratia and Citrobacter (KESC) group directly from clinical specimens. Carbapenems, successfully used to treat multi-resistant Gram-negative bacterial infections, including ESBL positive strains, are not efficacious against the Enterobacteriaceae resistant to carbapenems, thus generating a significant risk of hospital-acquired infections. 11619 500 g 611619 100 g 621619 CRE-positive Escherichia coli Chromatic CRE supplement 81088 Liofilchem Chromatic OXA-48 Selective chromogenic medium for the screening of OXA-48 type Carbapenem-Resistant Enterobacteriaceae. OXA-48 CRE are multi-resistant bacteria potentially responsible of hospital infections. The detection of OXA-48 CRE carriers by Chromatic OXA-48 can prevent and help surveil those infections. Chromatic OXA-48, with its own proprietary formulation, includes an antimicrobial agents and chromogenic substrata mixture that allows the selective growth of OXA-48 CRE and the identification of Escherichia coli (red color), Klebsiella spp. (Blue-violet), Enterobacter spp. (blue-green), Citrobacter spp. (blue with red halo). OXA-48 positive Enterobacter cloacae 11631

Liofilchem Chromatic VRE Chromogenic medium for screening vancomycinresistant enterococci. Chromatic VRE contains a mixture of antibiotics including vancomycin for screening Vancomycin-resistant enterococci (VRE) and provides presumptive identification of Enterococcus faecium and Enterococcus faecalis directly from clinical specimens. VRE have recently been recognized as one of the most severe cause of nosocomial infections. An intrinsic resistance (vanc, vand, vane, vanf etc) is found in E. gallinarum and E. casseliflavus/e. flavescens and shows low resistance to vancomycin. Instead, an acquired resistance of vancomycin in enterococci (vana & vanb types) is mostly detected in E. faecium and E. faecalis. The prompt detection of Vancomycin-resistance of E. faecium and E. faecalis is basic for avoiding the spread of this resistance to more virulent such as S. aureus. Enterococcus faecium DSM 13590 11621 Liofilchem Chromatic MRSA Selective chromogenic medium for isolating methicillin- resistant Staphylococcus aureus. Methicillin resistant Staphylococcus aureus (MRSA) caused an increasing number of hospital infections in the recent years. A wide range of antimicrobial compounds, including the beta-lactam antibiotics, result unsuccessful for treating the methicillin resistant S. aureus. 10599 500 g 610615 100 g 620615 Chromatic MRSA supplement 81078 Staphylococcus aureus ATCC 43300 * Liofilchem Chromatic Staph aureus Selective chromogenic medium for isolating Staphylococcus aureus. Staphylococcus aureus is a one of the most commonly found bacteria. Staphylococcus aureus can be pyogenic and toxinogenic, it is a commensal human germ (half of the population hosts S. aureus). It is also often detected in in clinical specimens and food. Staphylococcus aureus today is a serious and diffused health problem. Staphylococcus aureus ATCC 25923 *, Staphylococcus sciuri ATCC 29062 * 11616 6 bottles x 100 ml 481160 500 g 610616 100 g 620616 Chromatic Staph aureus supplement 81085

Liofilchem Chromatic MH Chromogenic Muller Hinton for presumptive identification and susceptibility testing of various microorganisms from clinical specimens. In the Intensive Care Unit the mortality rates for VAP, sepsis, surgical site or intra-abdominal, catheter related infections are critically high. Direct M.I.C. on CSF, positive blood culture bottles and other specimens from critical patients and direct M.I.C. on bronchial aspirates from patients with VAP can contribute with timely and essential information to save the life of patients. 11618 500 g 611618 100 g 621618 Mixed culture with MIC Test Strip Liofilchem Chromatic Detection Chromogenic medium for enumeration and identification of microorganisms from urinary specimens and food. Chromatic Detection allows an easy and reliable differentiation of a wide range of species, complete in case of urine samples. The addition of various antibiotics to the Chromatic Detection medium is also useful for the detection of critical nosocomial and multiple resistant microorganisms. 11611 6 bottles x 100 ml 481130 500 g 610612 100 g 620612 P. aeruginosa, E. coli, E. faecalis, K. pneumoniae, P. mirabilis, S. aureus Liofilchem Chromatic GBS Selective and differential chromogenic medium for isolating Group B streptococci (Streptococcus agalactiae). Streptococcus agalactiae (GBS) is the main cause of infection in new born of industrialized countries. The risk of infection arises in pregnant women with a vaginal colonization by GBS. 11639 Streptococcus agalactiae

Liofilchem Chromatic Candida Selective chromogenic medium for isolating and differentiating Candida species. Candida species are often responsible of serious nosocomial and systemic fungal infections. Candida species are usual commensal yeasts present in the human skin, gastro-intestinal tract and vagina, which can occasionally become opportunistic pathogens. 11612 6 bottles x 100 ml 481110 500 g 610613 100 g 620613 60 mm 163692 C. albicans ATCC 10231 *, C. tropicalis ATCC 750 *, C. krusei ATCC 6258 * Liofilchem Chromatic Bacillus cereus Selective chromogenic agar for isolating and differentiating Bacillus cereus from food samples. Thanks to its ability to form spores, Bacillus cereus is an organism found in soil, vegetables, animal hair, water and sediments, therefore often associated to foodborne diseases such as vomit and diarrhea. Chromatic Bacillus cereus Agar allows the growth of Bacillus cereus in blue/green colonies. Antibiotic compounds included in the medium inhibit the majority of Gram-negative organisms and many Gram-positive bacteria including Staphylococcus aureus, enterococci and most of bacilli other than Bacillus cereus. 11628 Bacillus cereus ATCC 11778 * Liofilchem Chromatic Salmonella Selective chromogenic medium for isolating and differentiating Salmonella spp. Salmonella spp. is found in the environment and in cold- and warmblooded animals including humans. Salmonella spp. causes typhoid fever, paratyphoid fever, and foodborne illness. Salmonella infections are zoonotic and can be transferred between humans and nonhuman animals. Infections are also caused by ingestion of contaminated food and are particularly hazardous in older adults and those who are immunocompromised. Salmonella enterica subsp. enterica serovar Typhimurium ATCC 14028 * 11614 6 bottles x 100 ml 481140 500 g 610611 100 g 620611 TWEEN 20 Supplement 80032

Liofilchem Chromatic Coliform Agar ISO Chromogenic medium for detection and enumeration of E. coli and coliform bacteria in water, according to ISO 9308-1. Chromatic Coliform Agar ISO is the new culture medium for enumerating coliform bacteria and E. coli in water samples with low bacterial background flora to replace Lactose TTC agar in accordance to the ISO 9308-1 (effective on Sept 16th, 2014). Chromatic Coliform Agar ISO contains enzymes that allow the simultaneous identification of several microorganisms in 24 hours, by defined colors of the colonies. Coliform bacteria and E. coli are potential pathogens found in samples with low background flora such as drinking water, disinfected pool water and finished water from drinking water treatment plants. Escherichia coli ATCC 25922 * 11630 6 bottles x 100 ml 481190 500 g 610630 100 g 620630 60 mm 163852 Liofilchem Chromatic Coli Coliform Selective chromogenic medium for E. coli and coliforms isolation and enumeration in foods and water. The detection of E. coli and coliforms is one of the main criteria to define the quality of water and food. Drinking water can be contaminated by E. coli following a period of intense rains, or because of an insufficient treatment. Coliforms, lactose fermenting Enterobacteriacae, are bacteria found in the intestinal flora of blooded animals, in soil and water. Escherichia coli and thermotolerant Klebsiella are commonly responsible of fecal contaminations, through animal waste. E. coli ATCC 25922 *, K. pneumoniae ATCC 13883 * 11613 6 bottles x 100 ml 481120 500 g 610610 100 g 620610 60 mm 163702 Liofilchem Chromatic E.coli O157 Selective chromogenic medium for detecting E. coli O157. Escherichia coli O157:H7 causes severe foodborne illness, and is a member of a class of pathogenic E. coli known as verocytotoxin producing E. coli (VTEC). Infection often leads to hemorrhagic diarrhea, and occasionally to kidney failure, especially in young children and elderly persons. Transmission is via the fecal-oral route, and most illness has been associated with eating undercooked, contaminated ground beef, swimming in or drinking contaminated water, and eating contaminated vegetables. Escherichia coli O157:H7 ATCC 35150 * 11610 500 g 610614 100 g 620614

Liofilchem O.A. Listeria agar Selective differential chromogenic medium for detecting and counting Listeria monocytogenes from food samples (ISO 11290). Listeria monocytogenes is one of the most virulent foodborne pathogens, responsible for an increasing amount of deaths worldwide annually. Listeriosis is the major cause of death among foodborne bacterial pathogens. Infections by Listeria monocytogenes can happen in any stages of food processing. Listeria monocytogenes can be found in the fecal matter, soil and waste waters. Listeria monocytogenes ATCC 35152 * 10620 500 g 610601 100 g 620601 O.A. LISTERIA supplement 81074 Liofilchem TBX agar Selective chromogenic medium for detecting and enumerating E. coli in food according to ISO 16649. X-glucuronide, contained in the TBX agar formulation, is the chromogenic agent that allows the determination of the β-dglucuronidase activity, which is a highly specific enzyme for E. coli. Gram-positive bacteria are inhibited by bile salts. 10522 6 bottles x 100 ml 481170 500 g 610224 100 g 620224 Escherichia coli ATCC 25922 * Liofilchem Chromatic Vibrio Chromogenic medium isolating and differentiating V. parahaemolyticus, V. vulnificus and V. cholerae. V. cholerae, V. parahaemolyticus and V. vulnificus have the potential to be foodborne, and are most often associated with the consumption of raw, or undercooked, shellfish. V. cholerae is the cause of outbreaks and epidemics of cholera, V. parahaemolyticus is the species most frequently associated with foodborne disease in humans, V. vulnificus is an occasional cause of serious infections especially in case of wound contact in the marine environment that can cause primary septicaemia in vulnerable individuals with consequent high mortality rate. 11633 500 g 610633 100 g 620633 Vibrio vulnificus ATCC 27562 *

Liofilchem Chromatic Pseudomonas Chromogenic medium for detection of Pseudomonas spp. from clinical specimens and environmental samples. Pseudomonas are ubiquitous bacteria, able to grow at low temperature (psychrophilic strains) and consequently to contaminate foodstuff and beverages stored in the refrigerator. Pseudomonas strains can occasionally be isolated from the intestinal flora of humans or animals. P. aeruginosa has developed resistance to many antibiotics and is rated as one of the main causes of intensive care unit (ICU) related pneumonia. 11635 Pseudomonas aeruginosa ATCC 9027 * Combo plates available # Description packaging Ref. Chromatic Staph.aureus / Chromatic MRSA 18007 Chromatic CRE / Chromatic OXA-48 18023 Chromatic Detection / Chromatic ESBL 18011 Chromatic CRE / Chromatic ESBL 100 plates 18021 18021* Chromatic Detection / TSA Blood 100 plates 18008 18008* # Minimum orders are required. Custom versions on request. Liofilchem and the Liofilchem company logo are registered trademarks belonging to Liofilchem s.r.l. ATCC *: The ATCC Licensed Derivative Emblem, the ATCCC Licensed Derivative word mark, and the ATCC catalog marks are trademarks of ATCC. Liofilchem is licensed to use these trademarks and to sell products derived from ATCC cultures. Liofilchem s.r.l. Via Scozia, Zona industriale 64026, Roseto degli Abruzzi (TE), Italy www.liofilchem.com Liofilchem is ISO 9001 and ISO 13485 certified 6551068 Rev. 10-20.11.2018 Liofilchem 2018 printed in Italy