Efficacy of abamectin against gastrointestinal nematodes in calves

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. - - %, Ostertagia Strongyloides Trichostrogylus Haemonchus.. %, % %.. %,. Abstract Efficacy of abamectin against gastrointestinal nematodes in calves B. A. Mohammed Department of Internal and Preventive Medicine, College of Veterinary Medicine, University of Mosul, Mosul, Iraq The objective of the current study was to evaluate the efficacy of abamectin in calves naturally infested with GIT parasites. 215 local breed calves were used in this study seven months to one year old males, and 8-15 kg weight. Result indicated that infestation rate were 42.8%, where as fecal examination & larval culture revealed the presence of 8 species of round worms. The highest rate of infestation showed to be by the larvae of Haemonchus species followed by Trichostrongylus, Strongyloides and Ostertagia respectively. Other species were observed less frequently. Among clinical sings, rough coat & loss of body condition were the most obvious symptoms in most of infected calves examined. The percentage of mixed infestation was 66.6% while the single infestation was 33.4%, the domination of light infestation was noted. The efficacy of abamectin against gastrointestinal parasites was % depending on the egg counts reduction, this efficacy persisted for days after treatments and then decline to about 97.98% at the end of this study. The blood picture was affected after treatment with abamectin which causes an improvement in the number of RBCs, Hb concentration values, packed cells volume and percentage of neutrophils and reduction in the percentage of eosinophils. Available online at http://www.vetmedmosul.org/ijvs % ( ) avermectin B1b % avermectin B1a C22 C23 ( ) Stryptomyces ( ) avermitalis

. \.( ) ( ).( ) \. -. \ % ( ). packed cells haemoglobin concentration volume ( ) rate.( ).( ).( ) ( ).( ) gama aminobutyric acid.( ). picrotoxin synapse ( ) ( ).( ) ( ).( ) / % Ostertagia,Haemonchus L4 Dictyocaulus viviparous placie,cooperia Ostertagia Hypobiotic larvae Trichstrogylus axei Ostertagia Cooperia H. placie Ostertagia D. viviparous radiatum.( ) ( ) \ > -

الايام 5 treat. control 7 6 5 4 النسبة المي وية للخمج :( ). الايام 5 25 15 5 معدل عدد البيوض \غم براز معدل عدد البيوض \ علاج معدل عدد البيوض \ سيطرة / :( ). abamectin %. \. SPSS %.%, % \ % %, % % % % %,.() %, %,..( ) L3 %, Haemonchus Ostretagia Strongyloides Trichostrongylus. % %, %,.( ) %,.( ) %, \ \ - ) - ) % ( % ( \ ( \>- ).( ) %

7 6 5 4 Chabertia ovina Strogyloides Oesophgostomum Bonostomum Nematodirus Trichostongylus Ostertagia Haemonchus 4 35 25 15 5 النس بة المي وي ة لتواج د دي دان المع دة الرابع ة والامع اء النسبة المي وية لشدة الخمج خمج خفيف( - 5 \بيضة) خمج متوسط( 5 - \بيضة) جمح شديد( بيضة ف ا آثر ( :( ). \ :( ). dysentry diarrhea pasty feces rough coat bottle jaw easily hair detached weakness 9 8 7 6 5 4 الخمج المفرد الخمج المشترك 7 6 5 4 النسبة المي وية لشدة الخمج النسبة المي وية لظهور العلامات السريرية مجموعة علاج \ قبل العلاج مجموعة علاج \ بعدالعلاج مجموعة السيطرة\قبل التجربة مجموعة السيطرة\بعد :( )..( ) :( )..( ).( )

. :( ) 6 **.1 ± 6.12 6.25 ± 4.6 / 7778 ± 223.58 746 ± 377.36 / 12.76 ±.35** 9.2 ±.44 / / 38.76 ± 1.16** 26.8 ±.98 %/ 36.32 ±.86 **.28 ±.82 %/ 55.24 ± 1.4 56.8 ± 1.7 %/ 5.68 ±.22 5.8 ±.29 %/ 2.68 ±.26 ** 7.64 ±.54 %/.16 ±.7.12 ±.6 %/.(P<.1) **. ( ) :( ) ( ) 6 ** 6.12 ±.1 7778 ± 223.58** 12.76 ±.35** 38.76 ± 1.16** 36.32 ±.86** 55.24 ± 1.4 5.68 ±.22** 2.68 ±.26**.16 ±.7 ( ) 6 4.91 ±.3 6466 ± 19.3.28 ±.35.92 ± 1.7.8 ±.59 57.56 ±.76 4.44 ±.37 6.64 ±.57.8 ±.5 / / / / %/ %/ %/ %/ %/ %/.(P<.1) **. Bonostomum Haemonchus ( ) Oesophagostomum Ostertagia, Trichostrongylus, Nematodirus, ( ) Chabertia Strongyloides. ( ) %, %, %, ( ) %, \ % ( ) ( ). %, ( ). - % -

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