Key Messages & RDE Priorities

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AWI Breech Strike R&D Technical Update Maritime Museum, Sydney 20 th August 2014 Geff Lindn Prgram Manager Prductivity and Animal Welfare AWI Key Messages & RDE Pririties

Key Messages Breech Strike Preventin

Key Messages: Breeding fr Breech Strike Resistance Breech Strike highly repeatable and heritable, cull struck sheep Strng relatinship between breech trait scres & breech strike; each 0.1 scre reductin reduces risk Key targets fr indicatr scres are: 2:2:3 Wrinkle Scre 2; Dag Scre 2 & Breech Cver Scre 3 (risk similar t mulesed ) Achieve by sheep selectin, mulesing, management r breech mdificatin Abve 2:2:3, risk f breech strike increases rapidly, Belw 2:2:3, risk f breech strike cntinues t decrease Cllecting mre data n urine stain likely t need scre 2 70 1.40 70 1.40 70 1.40 Frequency distributin (% animals) 60 50 40 30 20 10 1.20 1.00 0.80 0.60 0.40 0.20 Breech flystrike rate Frequency distributin (% animals) 60 50 40 30 20 10 1.20 1.00 0.80 0.60 0.40 0.20 Breech flystrike rate Frequency distributin (% animals) 60 50 40 30 20 10 1.20 1.00 0.80 0.60 0.40 0.20 Breech flystrike rate 0 1 2 3 4 5 0.00 0 1 2 3 4 5 0.00 0 1 2 3 4 5 0.00 pdag scre pbrwr scre purine scre

Key Messages: Breeding fr Breech Strike Resistance Wrinkle and Cver relatively quick prgress can be made in breeding terms.. less s fr super fines / fines Reducing dags is mre difficult in high dag cuntry, envirnmental causes f dags swamps genetic prgress Odur and bacteria may be imprtant factrs but will be sme time befre validated and usable by Industry May take sme pressure ff the need fr lw dag, lw urine stain and lw wrinkle?

Key Messages: Breeding fr Breech Strike Resistance Need t find & use high fleece weight, lw dag & lw wrinkle sheep Mre difficult in superfine and fine wl merins; less variatin Breeding Values can assist rate f gain especially when there are a) large numbers f traits t select fr b) reasnable number f traits negatively crrelated Fleece Weight and Micrn Fleece Weight and Wrinkle Fat and Prductivity (Fleece Weight and Reprductin) Wrm Egg Cunt and Dags It takes fcus, grup f fellw breeders n same path and time. t breed curve benders

Key Messages: Breeding fr Breech Strike Resistance Ram Breeding Industry is nw creating new lines f lw wrinkle, lw cver, lw wec, lw dag rams with high relatively fleece weight. Search criteria; Sire, <-0.3 Wrinkle, <-0.3 Cver<-0.1 Dag, Fat>0, Muscle>0, WEC <30, MP+ Order

Key Messages: Breech Mdificatin - alternatives Clips: Apprx 30,000 t 50,000 lambs per year Mstly reusing clips each year SkinTractin: Negtiating label fr APVMA apprval Develpment and Cmmercialisatin Liquid Nitrgen: Imprving equipment and prcess Cmmence larger trials Laser Technlgy: Reviewing new technlgy and need fr further prf f cncept studies Encuraging welfare assessments t date fr all alternatives

Key Messages: Breech Mdificatin Pain Relief Tri-Slfen Survey results; 60% t 70% f mulesed lambs treated Tri-Slfen, rapid uptake Reclassified frm S4 t S5 categry chemical, ver the cunter sales started NMAP Training Being updated by Animal Health Australia and WlPrducers Australia Newly endrsed under the Australian Qualificatins Framewrk (AQF) system Opens access t Gvernment Industry Training Funds Can be used as part f Certificate 3 and 4 in Agriculture Train The Trainer training late 2014 Aim t recmmence NMPA training early 2015 Kndinin updating existing training recrds and apprvals

Key Messages: Sheep Management Imprved pastures and high stcking rates have increased risk f breech strike ver last 50 years Tail dcking methds similar fr strike risk and welfare Castratin methds similar fr strike risk and welfare Dicyclanil and Cyrmazine prvide gd prtectin fr label perids listed n prduct labels Use existing chemicals wisely t delay nset f resistance

Key Messages: Sheep Management Harder t get new chemicals registered, csts much higher Wrms and flies Imprving ur understanding hw current chemicals wrk at DNA level. Targeting genes specific t parasite gd way frward. DNA f pest, hst, bacteria and their interactin with Envirnment prviding new leads

Key Messages: Grwer case studies unmulesed sheep Plan, plan, plan, dn t just stp mulesing need t rebalance basket f all ther cntrl prcedures Wrk in with ther like minded breeders Need clear fcus n a balanced prfitable merin and hw t achieve it; set breeding targets Need t manage bth upsides and dwnsides f intrducing genetics MUST practively market sheep and wl Whle business needs t be n bard

Future RD&E Optins and Pririties?

Future RD&E pririties - Breeding Odur and Bacteria Validating early results Which durs attract r repel flies? Rle f misture in creating high risk cnditins Will dur take pressure ff wrinkle, dag, breech cver, urine stain? Urine stain What causes sme sheep t get urine stain and thers nt? Mre data t create breeding value Flystrike Trials? Prgeny testing under challenging cnditins Cmparisn f breeding and mdificatin alternatives?

Future RD&E pririties - Breeding Imprving rates f gain, wrinkle, dag, cver, prductivity Upgrades t DashBard (assess rate f gain) and Matesel (jining strategy) Making ASBV technlgy mre accessible, reducing adptin barriers Crrelatin between Dags and Faecal Cnsistency Sheep CRC Infrmatin Nucleus Flck analysis encuraging Review Mt Barker WA Flck data Gd crrelatin wuld allw selectin against dags in lw dag envirnments Dags Reducing dags; mstly hypersensitivity, gut reactin t lw but increasing larvae Genmic ptins? Imprving adult wrm cntrl

Future RD&E pririties - Breeding Breeding Value fr Flystrike / Welfare? Review pst dur and bacteria R&D Sheep Genmics? Risk and Return Genmics, discipline with very rapid prgress, but lw return n investment? Where t with flystrike!! Further sampling/strage f Breech Strike Resistance Flcks Review analysis methdlgy, cmbine with Sheep CRC and MLA data Cmmercial flck testing? Mdelling f achievable rates f welfare and prductivity imprvements frm sheep selectin and breeding prgram technlgies

Future RD&E pririties - Management Fly genme ffering new sights int new chemicals / vaccines / preventin regimes What d the genes unique t the blwfly cntrl Smell r lfactry genes f special interest, hw best t knck ut r cnfuse? Cst benefit f 6 mnth r 9 mnth shearing prgrams Imprved castratin and tail dcking methds

Future RD&E pririties Breech Mdificatin SkinTractin t market Further Liquid Nitrgen Trials Laser further prf f cncept studies - new technlgy? Cmparative efficacy and welfare assessments f alternatives and pain relief ptins Publicatin f results

Future RD&E pririties Pain relief Setting Maximum Residue Levels fr Pain Relief Actives Funding needed fr ff patent actives, funding negtiatins taking place Melxicam Ligncaine Bupivicaine Cetrimide Hpefully MRLs fr sheep can be set next 1-2 years With Hlding Perids then likely t be less than 14 days?? MRLs & WHPs will give whle supply chain mre cnfidence and uses

Future RD&E pririties Pain relief Onging R&D; pre and pst perative ptins Practical Delivery methds Better drug cmbinatins Lnger acting prducts Better accunting fr the benefits f pain relief Establishing better pain benchmarks

Future RD&E pririties Extensin The R&D f Extensin, hw t lift engagement & adptin The best RD&E has strng breeder invlvement At the start, planning In the middle, verseeing At end, marketing the utcmes Prducer Demnstratin Sites; see and tuch Field Days, Sales, Grwer Events ParaBss (FlyBss, WrmBss, LiceBss) AWI Netwrks, Breeder grups Publicatins Case Studies Industry Champins Greater use f digital media ptins, Apps

Future RD&E pririties Cnsultatin 6 mnthly Australian Veterinary Assn and annual Genetic Review f AWI Breech strike preventin prgram AWI Animal Welfare Frum cntinues t meet every 6 mnths Cnsultatin with State Welfare and Federal Agencies Technical RD&E Update every 2 years Feedback and Cnsultatin with Supply Chain Custmers and Retailer Assciatins Onging breeder feedback - Breech Strike RD&E Strategy is updated each year

June 20, 2008