BC Children s Hospital and BC Women s Hospital & Health Centre CUMULATIVE ANTIBIOGRAM 2017 Division of Medical Microbiology Department of Pathology and Laboratory Medicine Page 1 of 5
GRAM-POSITIVE BACTERIA Total Number of Isolates (N)* Ampicillin Amox/Clav Penicillin PERCENTAGE (%) OF SUSCEPTIBLE CLINICAL ISOLATES Cloxacillin Cefazolin Cephalexin Ceftriaxone (CNS) Ceftriaxone Vancomyci n Erythromy cin Clindamyci n Trimeth/Sulfa Doxycycline Nitrofurant oin# Linezolid Enterococcus faecalis 233 100 R R 100 96 Enterococcus faecium** 37 32 R R 62 100 S. aureus -all isolates 1439 80 80 80 80 100 70 78 94 97 99 MRSA isolates only 307 R R R R R R R 100 41 66 87 94 99 Coagulase Negative Staphylococcus 169 20 20 100 87 100 Streptococcus pneumoniae ** 89 100 97 α 100 82 89 Viridans Streptococci ** 65 70 65 92 100 Streptococcus pyogenes (Group A) 546 100 100 100 92 92 Legend R This organism is inherently resistant to this antibiotic * Not all isolates had susceptibility testing for all antibiotics ** 2016 and 2017 numbers combined due to small number of annual isolates # Tested on urine isolates only, should only be used for treatment of simple cystitis Susceptibilities reflect non-cns infection breakpoints (except ceftriaxone) α Based on 31 isolates Page 2 of 5
PERCENTAGE (%) OF SUSCEPTIBLE CLINICAL ISOLATES GRAM-NEGATIVE BACTERIA Total Number of Isolates (N)* Ampicillin Amox/Clav Pip/Tazobacta m Cefazolin Cephalexin Cefotaxime Ceftazidime Meropenem Gentamicin Tobramycin Trimeth/Sulfa Ciprofloxacin Nitrofurantoin # Escherichia coli (all sites) 700 46 45 96 34 86 100 91 91 70 84 Escherichia coli (urine only) 556 50 49 98 88 90 100 92 92 73 88 99 Klebsiella pneumoniae 72 R 60 79 45 68 100 69 71 90 72 38 Enterobacter cloacae complex (asburiae, kobei, cloacae) 41 R R 100 95 95 73 100 28 Proteus mirabilis 47 83 91 100 0 94 98 100 98 98 89 100 0 Pseudomonas aeruginosa 174 R R 69 R R R 90 87 90 91 R 92 R Haemophilus influenzae 109 64 95 100 65 Legend R This organism is inherently resistant to this antibiotic * Not all isolates had susceptibility testing for all antibiotics # Tested on urine isolates only, should only be used for treatment of simple cystitis Isolates from Cystic Fibrosis patients are included Page 3 of 5
Infection Prevention & Control Additional Precautions Contact Contact Plus Droplet HCW: gloves and gowns for direct care HCW: gloves and gowns for direct care Use sporicidal disinfectant HCW: surgical / procedure mask and eye protection Patient: mask when outside room if possible Droplet & Contact Combine all elements of both Airborne Negative pressure room with door closed HCW: N95 Respirator on entry Patient: surgical / procedure mask when outside room Airborne & Contact Combine all elements of both Routine practices are used with ALL patients at ALL times in ALL health care settings. Your 4 moments for Hand Hygiene: 1. Before patient / patient environment contact 2. Before aseptic procedure 3. After body fluid exposure risk 4. After patient / patient environment contact Page 4 of 5
REVISION LOG Version Description of Change Revision Date Implementation Date 1.1 Initial document upload into QMS Nov 21, 2018 Nov 21, 2018 Page 5 of 5