1. Title of Subject: Tumor viruses and oncogenes DEPARTMENT OF MEDICAL MICROBIOLOGY semester: 2 nd Coordinator: Dr. György Veress Instructors: Dr. György Veress Entrance conditions: Final exam from Medical Microbiology Molecular biology of cell transformation Activation of oncogenes and inactivation of tumor suppressor genes Oncoproteins DNA tumorviruses RNA tumorviruses Gene rearrangements in human tumors Mechanisms of tumor suppressor gene inactivation in human tumors Human DNA tumorviruses Human RNA tumorviruses 2. Title of Subject: Some theoretical and practical aspects of Medical Mycology semester: 1 st and/or 2 nd no. of lessons: 20 Coordinator: Dr. Béla Szabó Instructors: Dr. Béla Szabó Entrance conditions: Final exam from medical microbiology The taxonomy and morphology of fungi of medical importance Multiplication of fungi: theory and practice 1
Pathogenesis of fungal disease I. Pathogenesis of fungal disease II. Diagnosis of fungal diseases (theory) Diagnosis of fungal diseases (practice) 7 th week: Treatment of fungal diseases 8 th week: Dermatomycoses I. 9 th week: Dermatomycoses II. 10 th week: Systemic mycoses 3. Title of Subject: Interpretive clinical bacteriology and virology semester: 1 st no. of lessons: 14 Coordinator: Dr. József Kónya Instructors: Dr. József Kónya, Dr. László Majoros Entrance conditions: Final exam in Medical Microbiology Blood stream infections Bacterial respiratory tract infections Bacterial infections in Stomatology and Oto-Rhino-Laryngology Bacterial and viral infections of genital organs Diagnostic laboratory assays in HIV infections Intrauterine and perinatal infections Viral hepatitis Herpesviridae, Mononucleosis syndrome Viral infections in post-transplant patients 7 th week: Central nervous system infections 2
4. Title of Subject: Medical Parasitology semester: 1 st Coordinator: Dr. Judit Szabó Instructors: Dr. Judit Szabó Entrance conditions: Final exam in Medical Microbiology Protozoa I Protozoa II Cestodes Flukes Roundwormes I. Roundwormes II. 6. Title of Subject: The problem of resistance to antibiotics. Antibiotic policy year(s): students in 3 rd, 4 th, 5 th, year(s) semester: 1 st or 2 nd no. of lessons: 15 (5x3) Coordinator: Dr. Gábor Kardos Instructors: Dr. Gábor Kardos Entrance conditions: Types, development and spread of antibiotic resistance. Genetic resistance, crossresistance. Resistance to antibiotics targeting the cell wall 3
Resistance to antibiotics targeting the ribosome Resistance to antibiotics with other mechanism of action. Resistance to antimycobacterial agents Problem of multiresistance. Choosing an appropriate antibiotic, antibiotic policy 7. Title of Subject: Diagnosis and therapy of invasive fungal infections semester: 1 st or 2 nd (4x3) Coordinator: Dr. Gábor Kardos Instructors: Dr. Gábor Kardos Entrance conditions: succesful final examination in medical microbiology Epidemiology of invasive fungal infections, risk factors, patient groups at risk. Disseminated yeast infections (candidiasis, cryptococcosis). Disseminated disease due to molds (aspergillosis, mucormycosis, fusariosis). Antifungal treatment. Mechanisms of resistance to antifungals. Prevention of fungal infections, chemo-prophylax 8. Title of Subject: Microbiology of sepsis year(s): students in 4 th, 5 th, 6 th year(s) semester: 1st Coordinator: Dr. Judit Szabó Instructors: Dr. Judit Szabó Entrance conditions: Final exam in Medical Microbiology Pathogenesis of sepsis 4
Rules of adequate collection of specimen Automatic bloodculture systems Interpretation of culture results Predictive value of culture results Adequate antibiotic therapy in sepsis 9. Title of Subject: Molecular diagnosis of multiresistant bacteria year(s): students in 4 th, 5 th, 6 th year(s) semester: 1st Coordinator: Dr. Judit Szabó Instructor: Dr. Judit Szabó Entrance conditions: Final exam in Medical Microbiology Methicillin resistant S.aureus (MRSA) Vancomycin intermediate sensitive S. aureus (VISA) Vancomyin resistant enterococci (VRE) Extended spectrum beta-lactamase (ESBL) producing enterobacteria Carbapenem resistant pseudomonas Multiresistant acinetobacter 10. Title of Subject: Laboratory diagnosis of anaerobic bacteria year(s): students in 4 th, 5 th, 6 th year(s) semester: 1st 5
Coordinator: Dr. Judit Szabó Instructors: Dr. Judit Szabó Entrance conditions: Final exam in Medical Microbiology Gram-positive anaerobic cocci Gram-negative anaerobic cocci Gram-positive anaerobic spore forming rods Gram-positive anaerobic none spore forming rods Gram-negative black pigmented anaerobic rods Gram-negative non pigmented anaerobic rods 11. Title of Subject: Fingerprinting of pathogens, methods in epidemiological tracing years: Medical students: III., IV., V., VI., Dentistry: IV., V.., Pharmacy: IV., V. no. of lessons : 21 (7x3) Coordinator: Dr. Gábor Kardos Teachers: Dr. Gábor Kardos Entrance conditions : successful end-semester exam of medical/pharmaceutical microbiology 1st week: Significance, uses and applications of tracing. 2nd week: Phenotype-based classical methods: bio-, resisto-, bacteriocin-, sero and phage typing. 3rd week: Phenotype-based molecular methods: multilocus enzyme electrophoresis, chemical fingerprinting 4th week: Genotype-based methods: PCR-methods. 5th week: Genotype-based methods: RFLP and sequence based methods. 6th week: Computerized analysis, international databases and surveillance networks. 7th week: Practical applications, case studies (food-borne zoonoses, nosocomial infections). 6
12. Title of Subject: Travel and infectious diseases, imported infections. years: Medical students: IV., V., VI., Dentistry: IV., V.., Pharmacy: IV., V. no. of lessons : 21 (7x3) Coordinator: Teachers: Dr. Gábor Kardos Dr. Gábor Kardos, Dr. László Majoros, Dr. Krisztina Szarka Entrance conditions : successful end-semester exam of medical/pharmaceutical microbiology 1st week: Geography of diseases. Classical bacterial infections: tuberculosis, trachoma, typhoid, cholera and pestis. (G.K.) 2nd week: Food- and waterborne pathogens: traveller s diarrhoea, leptospirosis. Tropical zoonoses. (G.K.) 3rd week: Tropical and subtropical mycoses. (L.M.) 4th week: HIV and AIDS. Viral hepatitis. (K. Sz.). 5th week: Arbo- and roboviruses. (K. Sz.). 6th week: Malaria and other protozoal diseases (G.K.). 7th week: Helminthic infections (G.K.) 13. Title of Subject: Infections of the immunocompromised years: Medical students: IV., V., VI., Dentistry: IV., V.., Pharmacy: IV., V. no. of lessons : 21 (7x3) Coordinator: Dr. László Majoros Teachers: Dr. László Majoros, Dr. Gábor Kardos, Dr. Krisztina Szarka Entrance conditions : successful end-semester exam of medical/pharmaceutical microbiology 1st week: Causes of compromised immun status. Patient groups (G.K.) 2nd week: Pathogens: Bacteria (G.K.). 3rd week: Pathogens: fungi (L.M.). 4th week: Pathogens: parsasites (G.K.). 5th week: Pathogens: viruses (K.Sz.). 6th week: HIV and AIDS (K.Sz.). 7th week: Characteristic infections in different patient groups (L.M.). 7
14. Title of Subject: Case studies in clinical microbiology years: Medical students: III., IV., V., VI., Dentistry: IV., V.., Pharmacy: IV., V. no. of lessons: 9 (3x3) Coordinator: Dr. László Majoros Teachers: Dr. László Majoros, Dr. Gábor Kardos, Dr. Krisztina Szarka Entrance conditions : successful end-semester exam of medical/pharmaceutical microbiology 1st week: Bacterialis infections. 2nd week: Mycosis cases. 3rd week: Viral infections. 15. Title of Subject: Infections spreading from animals to humans years: Medical students: IV., V., VI., Dentistry: IV., V.., Pharmacy: IV., V. no. of lessons : 21 (7x3) Coordinator: Teachers: Prerequisite : Dr. Krisztina Szarka Dr. Krisztina Szarka, Dr. Gábor Kardos, successful end-semester exam of medical/pharmaceutical microbiology 1st week: Reservoirs, vectors, spread routes. (K.Sz.) 2nd week: Food- and waterborne zoonoses. (G.K.) 3rd week: Rare but lethal: other bacterial zoonoses. (G.K.) 4th week: Arboviruses: insect bite and meningoencephalitis. (K. Sz.). 5th week: Roboviruses: rodents and hemorrhagic fever. (K. Sz.). 6th week: Avian influenza (K.Sz.). 7th week: Vector-borne protozoa and helminths (G.K.) 8