OFFICIAL UPDATES TO ICD-10

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Ratified by HoC/WHO at HoC meeting in Brazil, 2000 WORLD HEALTH ORGANIZATION Update Reference Committee 30 November 2000 OFFICIAL UPDATES TO ICD-10 The following pages include the official changes to the tabular list, instruction manual and alphabetical index of ICD-10. These changes were approved, in principle, at the Heads of Centres meeting in Paris in and ratified at the Heads of Centres meetings in Brazil, 2000. The source for each change is indicated, as is the implementation date. Relevant changes in other language versions of ICD-10 and in related tools will also have to be made and disseminated by the appropriate authority. (Note: Every effort has been made in the following pages to reproduce the content of the ICD-10 in the same format as the published volumes. Page references have not been used in all instances since these do not apply to electronic versions of the Classification. Additions/changes have been indicated through the use of instructions, underline and strikeout). This document is not issued to the general public, and all rights are reserved by the World Health Organization (WHO). The document may not be reviewed, abstracted, quoted, reproduced or translated, in part or in whole, without the prior written permission of WHO. No part of this document may be stored in a retrieval system or transmitted in any form or by any means electronic, mechanical or other without the prior written permission of WHO. Page 1

Ratified by HoC/WHO at HoC meeting in Brazil, 2000 Volume 1 TABULAR LIST Instruction Tabular list entries Source Date approved E84.1 Cystic fibrosis with intestinal manifestations Meconium ileus (P75*) Major/ Minor update Implementation date Add exclusion note Excludes: meconium obstruction in cases where cystic fibrosis is known not to be present (P76.0) Add exclusion note L90.0 Lichen sclerosus et atrophicus Excludes: lichen sclerosus of external genital organs:.female (N90.4). male (N48.0) NORDIC Add inclusion term N48.0 Leukoplakia of penis Balanitis xerotica obliterans Kraurosis of penis NORDIC Modify title Add inclusion term N48.6 Induratio penis plastica Peyronie s disease Plastic induration of penis NORDIC Add inclusion term Q93.5 Other deletions of part of a chromosome Angelman syndrome France Page 2

Ratified by HoC/WHO at HoC meeting in Brazil, 2000 Volume 3 ALPHABETIC INDEX Instruction Alphabetic index entries Source Date approved Add lead term and code Revise code Angelman syndrome Q93.5 France Balanitis (circinata) (erosiva) (gangrenosa) (infectional) (nongonococcal) NORDIC (phagedenic) (vulgaris) - xerotica obliterans N48.0 Major/ Minor update Implementation date Delete and add modifiers Revise indentation level Add lead term and code Revise code Revise subterm and code Cystocele (-rectocele) ( -urethrocele) Derangement - knee NEC - - current injury - - specified NEC M23.8 Happy puppet syndrome Q93.5 France Neuropathy, neuropathic G62.9 - diabetic (see also E10-E14 with fourth character.4) E14.4 G63.2* - - mononeuropathy E14.4 G59.0* Page 3

Ratified by HoC/WHO at HoC meeting in Brazil, 2000 Table of Drugs and Chemicals Instruction Alphabetic index entries Source Date approved Add term Add term Agonist - predominantly - - α-adrenoreceptor - - β-adrenoreceptor T44.4 T44.5 Y51.4 Y51.5 Add term and codes Aminoglycoside T36.5 Y40.5 Analgesic NEC - nonopioid T39.9 X40.- X60.- Y10.- Y45.9 Major/ Minor update Implementation date Anesthetic NEC (see also Anesthesia) - inhaled T41.0 Y48.0 Antagonist - α-adrenoreceptor NEC - β-adrenoreceptor NEC T44.6 T44.7 Y51.6 Y51.7 Antiandrogen NEC T38.6 Y42.6 Antidepressant NEC - monoamine-oxidase-inhibitor T43.1 X41.- X61.- Y11.- Y49.1 Antidysrhythmic NEC T46.2 Y52.2 Antiepileptic T42.7 X41.- X61.- Y11.- Y46.6 - mixed NEC T42.5 X41.- X61.- Y11.- Y46.6 - specified NEC T42.6 X41.- X61.- Y11.- Y46.6 Antiestrogen NEC T38.6 Y42.6 Page 4

Ratified by HoC/WHO at HoC meeting in Brazil, 2000 Antigonadotrophin NEC T38.6 Y42.6 Antihyperlipidemic drug T46.6 Y52.6 Delete term & Anti-inflammatory drug, local, revise codes NEC T39.3 X40.- X60.- Y10.- Y45.9 - local T49.0 Y56.0 - nonsteroidal NEC T39.3 X40.- X60.- Y10.- Y45.3 - specified NEC T39.3 X40.- X60.- Y10.- Y45.8 Revise term & codes Antiparasitic drug, local (systemic) - local - specified NEC T37.9 T49.0 T37.8 Y41.9 Y56.0 Y41.8 Antipsychotic drug NEC - phenothiazine T43.3 X41.- X61.- Y11.- Y49.3 Benzothiadiazide T50.2 Y54.3 Blockers, calcium-channel T46.1 Y52.1 Congenor, anabolic T38.7 Y42.7 Delete term & Depressant, appetite T50.5 Y57.0 codes - appetite T50.5 Y57.0 - muscle tone, central, NEC T42.8 X41.- X61.- Y11.- Y46.8 Diuretic NEC - loop [high-ceiling] T50.1 Y54.4 Gas - therapeutic T41.5 Y48.5 Glucocorticoid T38.0 Y42.0 Glycoside, cardiac-stimulant T46.0 Y52.0 Page 5

Ratified by HoC/WHO at HoC meeting in Brazil, 2000 Hematological agent - specified NEC T45.9 T45.8 Y44.9 Y44.9 Iminostilbene T42.1 X41.- X61.- Y11.- Y46.4 Immunological agent T50.9 Y59.9 - specified NEC T50.9 Y59.8 Inhibitor - angio-tensin-converting enzyme - carbonic-anhydrase T46.4 T50.2 Y52.4 Y54.2 Laxative NEC - osmotic - saline - stimulant T47.3 T47.3 T47.2 Y53.3 Y53.3 Y53.2 Narcotic NEC - synthetic NEC T40.6 T40.4 X42.- X42.- X62.- X62.- Y12.- Y12.- Y45.0 Y45.0 Neuroleptic drug NEC - butyrophenone - phenothiazine - thioxanthene T43.4 T43.3 T43.4 X41.- X41.- X41.- X61.- X61.- X61.- Y11.- Y11.- Y11.- Y49.4 Y49.3 Y49.4 NSAID NEC T39.3 X40.- X60.- Y10.- Y45.3 Ophthalmological drug NEC T49.5 Y56.5 Opioid NEC T40.2 X42.- X62.- Y12.- Y45.0 Otorhinolaryngological drug NEC T49.6 Y56.6 Oxazolidinedione T42.2 X41.- X61.- Y11.- Y46.1 Page 6