VIPs in Zurich. Very Important Parasites in Zurich from fundamental to applied research

Transcription

1 Institute of Parasitology European Veterinary Parasitology College (EVPC) VIPs in Zurich Very Important Parasites in Zurich from fundamental to applied research 9 th 15 th September 2018 Continuing Education in Veterinary Parasitology for EVPC Diplomates and Residents 1

2 General Information Course Organizers: Manuela Schnyder, Hubertus Hertzberg, Peter Deplazes Manuela Schnyder Prof Dr med vet, PD, Dipl EVPC Institute of Parasitology, University of Zurich Winterthurerstrasse 266a 8057-Zurich Switzerland Tel: Secretariat: Esther Züst Institute of Parasitology, University of Zurich Winterthurerstrasse 266a 8057-Zurich Switzerland Tel: Venue: Institute of Parasitology (IPZ), Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 266a, 8057-Zurich, Switzerland. Institute of Parasitology 2

3 How to arrive: Travelling by plane: Zurich Airport (Zürich Flughafen) is located at 7 km from the venue, which can be reached by tram in about 30 min or taxi in about 15 min. Travelling by tram from Zurich Airport: Take tram 10 (direction Zürich HB) until tram station Milchbuck (14 stops) and from there tram 7 (direction Stettbach) or tram 9 (direction Hirzenbach) to tram stof Tierspital (next stop). Travelling by train: Zurich main train station (Zurich HB, Hauptbahnhof) can be reached from abroad with connections from all over Europe. It is located at 4 km from the venue, which can be reached by tram or by taxi in about 15 min. Travelling by tram from Zurich main train station: Take tram 7 (direction Stettbach) at tram stop Bahnhofstrasse/HB until tram stop Tierspital (11 stops). Travelling by car Zurich may be reached by car using existing major highways (National road tax), ensuring the shortest possible journey times. In the city or on the Campus parking is, however, severely limited and expensive; so you are encouraged to use public transportation. Public transportation in Zurich City of Zurich 3

4 No participation fee is asked. In the course are included: all lunches and coffee breaks as outlined in the program; field excursion; teaching and laboratory materials. Not included in the course are: travel to and from Zurich, accommodation, breakfast, and public transport tickets in Zurich. Deadline for application: 15 June 2018 Language: The official language will be English Number of participants: maximum 10 Participants selection: Priority: 1. EVPC Residents, 2. EVPC Diplomates, 3. Other interested candidates. Accommodation Zurich Tourismus Zurich Tourismus can assist in bookings of your accommodation: Tel: +41 (0) Also our secretaries will be happy to help you with the accommodation. Other possibilities Bed & Breakfast in or around Zurich: Youth hostels: Accademia Apartments: A coffee bar in Zurich, Kafi Schnaps, offers 5 guestrooms: Airbnb: Couchsurfing: 4

5 List of lecturers and assistants: Peter Deplazes, Prof, Dr med vet, Dipl EVPC (PD) Adrian Hehl, Prof, Dr, PhD (AH) Alexander Mathis, Prof, Dr sc nat (AM) Niels Verhulst, PhD (NV), Eva Veronesi, PhD (EV) Manuela Schnyder, Prof, Dr med vet, Dipl EVPC (MS) Felix Grimm, Dr phil II (FG) Walter Basso, Dr med vet, Dipl EVPC (WB) from Institute of Parasitology in Bern Hubertus Hertzberg, Dr med vet, Dipl EVPC (HH) Carmen Faso, Dr, PhD (CF) Lucienne Tritten, Dr, PhD (LT) Daniel Hegglin, Dr, PhD (DH) Sasa Stefanic, Dr med vet, PhD (SS) Deborah Joekel, PhD (Resident) Cristian Alvarez, PhD (Resident) Assistance: Nina Gillis-Germitsch, Dr med vet, PhD candidate (Resident candidate) Assistance: Philipp Kronenberger, PhD candidate (Resident candidate) 5

6 Program Sunday 9 th September 14:00 City tour (optional); Meeting point: Central (place near main station) 18:00 Welcome Dinner: Meeting point 17:45, Milchbuck tram stop Monday 10 th September 08:00 Meeting point: in front of the Institute of Parasitology 8:15-9:30: Lecture (PD): Cestodes - research and diagnostics major cestodes - Echinococcus multilocularis; E. granulosus; Taenia spp.; epidemiology, hosts, clinics, diagnostics, research at IPZ, animal models, antigens, test development 9:30-10:00: Coffee break 10:00-12:30: Lecture and Parasitological Zurich city tour (DH) Lecture: Ecology of Echinococcus hosts. Visit of Zurich with focus on Echinococcus multilocularis ecology; collection of environmental samples for parasitological investigations 12:30-13:30: Lunch at Mensa of Veterinary Faculty 13:30-16:00: Practical activity (PD, MS): Necropsy of foxes and rodents; recovery of parasites from fox intestine; (filtrationconcentration method); microscopy 16:00-16:30: Coffee break 16:30-18:30: Lecture (MS): Lungworms of carnivores Lecture: Lungworms of carnivores: epidemiology, hosts, clinics, diagnostics Practical activity: Microscopy of adult lung worms and larvae, morphological identification 6

7 Tuesday 11 th September 8:30-10:30: Practical activity (MS): Lungworms of carnivores Fox lung necropsy, microscopy of adult lung worms and larvae, morphological identification 10:30-11: 00: Coffee break 11:00-12:30: Lecture (CF, AH): Giardia duodenalis: A protozoon as a model for fundamental research Introduction into Diplomonad cell biology; architecture of the Giardia trophozoite, surface, cytoskeleton and replication; protein trafficking; host-pathogen interactions; stage conversion between trophozoites and cysts; Giardia research at IPZ. 12:30-13:30: Lunch at Mensa of Veterinary Faculty : Lecture (MS): Diagnosis and molecular epidemiology of Giardia duodenalis and control of giardiosis in dogs and cats Current taxonomy of Giardia; zoonotic potential; diagnosis, control measures in dogs and cats. 15:30-16:00: Coffee break 16: : Practical activity (FG, MS): Diagnostic of giardiosis Lecture: Diagnostic possibilities of Giardia infections in animals, choice of tests. Practical activity: Microscopy (SAFC, flotation methods), different commercial tests, coproantigen ELISA, immunofluorescence, PCR, rapid tests 7

8 Wednesday 12 th September Full day excursion with visits of goat and horse farm in alpine and prealpine areas of Switzerland 7:15: Departure in front of IPZ Lecture (HH): Management of gastrointestinal nematodes in ruminants and horses Gastrointestinal nematodes of small ruminants and horses, epidemiology with focus on the (pre-) alpine region, pasture management, clinic, diagnostic, control measures (monitoring strategies), anthelmintic resistance Practical activities (HH) Visit of a goat and a horse enterprise performing advanced parasite control measures. Collection and analysis of samples from animals and pasture; FAMACHA test Thursday 13 th September 8:15-10:15: Lectures (EV, NV): Lecture: Insect life cycle (mosquitoes, biting midges), invasive species, insect-bornepathogens, morphological identification introduction, vector competence, MALDI-TOF mass spectrometry, LAMP (loop-mediated isothermal amplification) - new tools for insect identification 10:00-10:30: Coffee break 10:15 12:15 Practical activity: Demonstration of insect vector trapping, breeding and feeding methods 12:15-13:00: Lunch at Mensa of Veterinary Faculty 13:00 16:00: Practical activity (EV, NV): Identification and vector competence Morphological insect identification, preparation of samples for MALDI TOF mass spectrometry, LAMP; vector competence studies: mosquito dissection and saliva collection 16:00-16:30: Coffee break 16: : Research in the field of cestodes and practical activites (PD, CA, DJ): actual projects in the cestode field: resistance against oncosphere invasion (DJ) and molecular epidemiology of Echinococcus spp. (CA); practical demonstration of egg detection in fox faeces and environmental samples 8

9 Friday 14 th September 8:00-9:45: Lecture and practical activity (WB): Cyst-forming coccidian parasites in veterinary medicine: clinical, diagnostic and epidemiological aspects. Lecture: Clinical, diagnostic and epidemiological aspects of toxoplasmosis, neosporosis besnoitiosis and sarcocystiosis in animals. Practical activity: Discussion of clinical cases and study of histological slides and fresh clinical samples. 9:45-10:15: Coffee break 10:15-11:00: Lecture (SS): Nanobodies, versatile tools for research, diagnostics and therapy 11:00-12:30: Lecture (AH): Toxoplasma gondii: from fundamental to applied research Introduction into Apicomplexa cell biology; novel experimental approaches in T. gondii systems biology; dissemination and persistence; immunological control; sexual development in the cat. 12:30-13:30: Lunch at Mensa of Veterinary Faculty 13:30-15:30: Lecture and practical activity (FG): Diagnostic laboratory Lecture: Accreditation of a diagnostic laboratory, planning, quality management, standardization Practical activity: Presentation of diagnostic highlights 15:30-16:00: Coffee break 16:30-17:30 Exam 19:00: Farewell Raclette Party for everyone at IPZ Saturday 15 th September 8:30-16:00: Optional for EVPC Residents: Study of IPZ specimen collection 9