The relevance of Gram-negative pathogens for public health situation in India
|
|
- Ruth Burke
- 5 years ago
- Views:
Transcription
1 The relevance of Gram-negative pathogens for public health situation in India Dr. Sanjay Bhattacharya MD, DNB, DipRCPath, FRCPath, CCT (UK) Consultant Microbiologist Tata Medical Center Rudolf Schulke Foundation Nov 2015, Hamburg, Germany
2 Overview WHO country statistics ESBL-carba R- North India ESBL- South India Carba-R- West India Stool surveil- East India Pediatric oncol infect Carba R in BSI Mortality in carba R GNB- BSI Colistin R Klebsiella Water quality monitoring GNB in hospital water Cost of Antibiotics in India Hospital cleaning monitoring in India Infection Vectors Hand Hygiene- historical legacy
3 WHO: Country statistics Germany India USA Population 82.7 million 1.25 billion 320 million GNI/capita (PPP) $ 44,540 $ 5,350 $ 53,960 Life expectancy (M/F) 79/83 yrs 65/68 yrs 76/81 yrs Healthy Life Expectancy Total expenditure on health per capita Total exp on health as % of GDP 71 years 57 years 70 years $4812 $215 $ % 4% 17.1%
4 WHO: Country statistics Germany India USA Doctors/ Nurses/ Access to improved water Access to improved sanitation Hospital beds/ Age standardized mortality rate by cause/100,000 Communicable diseases
5 ESBL and carbapenem resistance Gangaram Hospital, New Delhi (North India): ESBL E. coli in BSI (Blood Stream Infections) increased from 40% in 2002 to 61% in 2009 Carbapenem resistance in BSI increased from 2.4% in 2002 to 52% in Klebsiella pneumoniae Datta S et al. Indian J Med Res 135, June 2012, pp
6 ESBL South India 131 bacteremic patients (62.6% nosocomially acquired), ESBL production was detected in 73.28% of the isolates of E. coli and Klebsiella spp. The commonest source of bacteremia was the urinary tract (45.04%). The 14-day mortality rate was 23.6% J Assoc Physicians India Dec;58 Suppl:13-7.
7 Mumbai (West India): Molecular characterization of carbapenemresistant Enterobacteriaceae bla NDM-1 was the most prevalent carbapenemase and accounted for % (85/113) of the isolates. This was followed by bla OXA [4.42 % (n = 5)] % (21/113) of the isolates possessed dual carbapenemase genes. Eur J Clin Microbiol Infect Dis Mar;34(3):
8 Bhattacharya S.
9
10 Surveillance culture for MDRO detection Stool/ rectal swab- For MDRO GNB/ VRE Throat swab/ sputum- For MDRO- GNB/MRSA Nose swab/ groin swab/ Ulcer or wound swab- For MRSA Principle: culture of bacteria under antibiotic pressure Cefpodoxime Cefoxitin Vancomycin+ meropenem Meropenem ESBL detection MRSA and AmpC detection VRE detection Carbapenemase detection IQC- using CLSI criteria Bacteriology Quality Assurance EQAS- IAMM
11 Infections in Pediatric Oncology: Kolkata, East India In press. Bhattacharyya A. Indian Journal of Cancer
12 Data from Pediatric Blood Stream Infections: Jan 2015-Oct 2015 Tata Medical Center, Kolkata, India
13 Profile of organisms causing blood stream infections Acinetobacter 7% No. of isolates Other GNB 9% Enterococcus 5% Staph aureus 3% Other GPC 31% Candida 2% E. coli 18% Klebsiella 16% Pseudomonas 9% Acinetobacter E. coli Klebsiella Pseudomonas Candida Staph aureus Enterococcus Other GNB Other GPC N= 235; TMC; Dec 2014 to May 2015
14 Carbapenem Resistant Gram Negative Bacilli in Blood stream Infections blood cultures 235- positive BC (13%) 52 BC with carba R GNB (22%) Carba R- 2.9% of all Blood cultures Carba R E. coli Klebsiella Pseudomonas Acinetobacter Total numbers: E. coli= 45 Klebsiella= 41 Pseudomonas= 23 Acinetobacter= 18 Tata Medical Center, Kolkata, India; Dec 2014 to May 2015
15 Antibiotic sensitivity in Gram Negative Bacilli: blood stream infection data E. coli Klebsiella Pseudomonas Acinetobacter Amikacin Pip-taz Meropenem Colistin Tigecy Hospital antibiogram: Tata Medical Center, Kolkata, India : Dec 2014-May 2015
16 Antibiotic sensitivity in Gram Negative Bacilli: blood stream infection data Amikacin Gentamicin Cipro Ceftaz Meropenem E. coli Klebsiella Pseudomonas Acinetobacter Hospital antibiogram: Tata Medical Center, Kolkata, India : Dec 2014-May 2015
17 Organism Mortality from Carba resistant Gram Negative Bacilli Median age (years) Mortality Time to mortality after positive blood culture Time to mortality (Median) E. coli % NA NA Klebsiella pneumoniae Pseudomonas aeruginosa Acinetobacter baumanii Cumulative figures % 3-8 days 4.5 days % 1-5 days 1 day % 1-30 days 4.5 days %; Hemat: 43%; Solid: 26% 1-30 days 3 days N= 40; Tata Medical Center, Kolkata, India : Dec May 2015 data
18 Tata Medical Center, Kolkata, India The number of patients previously receiving colistin before isolation of CRK was 15 (62.5%) of 24. In total, 18 patients survived and 6 died (all cause mortality, 25%). The mean duration of hospital stay after detection of CRK was 17.9 days. Two patients received outpatient care only. The clinical infection types noted included: Sepsis/blood stream infection in 15 patients, pneumonia in 4 patients, Urosepsis in 1 patient, and soft-tissue infection in 1 patient. Three patients had asymptomatic colonization. Twenty (83.3%) of 24 patients had cases that came under the category of HCAI Ten (41.7%) of 24 patients had previous carbapenamase-producing Klebsiella isolated from 1 or more specimens before detection of CRK.
19 Klebsiella and antibiotic resistance: Figures Feb 4 th 2014-Oct 5 th 2015; Tata Medical Center, Kolkata, India Total no of Klebsiella isolated from all cultures-948 No of Klebsiella isolated from blood cultures-173 No of carbapenamase Klebsiella from blood cultures-97 No of colistin resistant Klebsiella isolated-15 No of colistin resistant Klebsiella from blood cultures-3
20 Colistin Resistant Klebsiella: Experience fromtata Medical Center, East India Previous Study June 2013 to Feb 2014 No:- 24 Previous Carbapenamase isolates-41.7% Previous colistin use- 62.5% All cause mortality- 25% This Study Feb 2014 to Oct 2015 No:-15 Previous Carbapenamase isolates % Previous Colistin use- 53.3% All cause mortality-46% Colistin-Resistant Klebsiella pneumoniae: Report of a Cluster of 24 Cases from a New Oncology Center in Eastern India- Gaurav Goel, Lalawmpuia Hmar, Maitrayee Sarkar De, Sanjay Bhattacharya, Mammen Chandy, infection control and hospital epidemiology august 2014, vol. 35, no. 8
21 What is India doing Greater awareness about issues related to antibiotic resistance: Chennai Declaration- IJC; 2013: 50, IJMM;2014: 32 Indian Council of Medical Research: IJMR; 2011: 134 Greater awareness about Infection Control issues especially in Private Hospitals NABH accreditation: Need for better sanitation, water hygiene and notification of GNB associated morbidity and mortality
22 Water quality monitoring Water chlorine level- Colorimeter O-toluidine/ Electronic Target: ppm Ref: WHO Water TDStotal dissolved salt- Conductivity meter; CSSD target<10 mg/l Source: Aesculap Water microbiology Membrane filtration Target: Coliforms- 0/100 ml Pseudomonas- 0/100 ml Ref: WHO, HPA (UK)
23 I n d i a n J o u r n a l o f P a t h o l o g y a n d M i c r o b i o l o g y ( 3 ), J u l y - S e p t
24 Cost of antimicrobial therapy in India Antibiotic Per day cost (adult) 10 day cost (adult) Cefoperazone-sulbactam Rs. 1,492 Rs. 14,920 Piperacillin-tazobactam Rs. 2,028 to Rs. 2,880 Rs. 20,280 to Rs. 28,880 Meropenem Rs. 2,697 to Rs. 7,488 Rs. 26,970 to Rs. 74,880 Colistin Rs. 3,000 to Rs. 5,670 Rs. 30,000 to Rs. 56,700 Tigecycline Rs. 5,600 to Rs. 5,980 Rs. 56,000 to Rs. 59,800 Per capita Gross National Income (PPP, 2013), WHO India $5350 Rs. 3,21,000 Bangladesh $2810 Rs. 168,600 Bhutan $7210 Rs. 7,32,600 Source: ( )
25 Assessment of cleaning Visual observation Ultra-violet light Microbiological assessment Swab culture PCR ATP bioluminescence
26 Infection vectors
27
28
29
30 Conclusion Gram negative pathogens represent a major public health problem in India There are many factors responsible for this problem The areas to focus for improvement: Hygiene and sanitation Proper waste disposal- biomedical and general waste Efficient data collection and its dissemination Regulation on the use of antibiotics Indian J Med Res 134, September 2011, pp
1/30/ Division of Disease Control and Health Protection. Division of Disease Control and Health Protection
Surveillance, Outbreaks, and Reportable Diseases, Oh My! Assisted Living Facility, Nursing Home and Surveyor Infection Prevention Training February 2015 A.C. Burke, MA, CIC Health Care-Associated Infection
More informationPresenter: Ombeva Malande. Red Cross Children's Hospital Paed ID /University of Cape Town Friday 6 November 2015: Session:- Paediatric ID Update
Emergence of invasive Carbapenem Resistant Enterobacteriaceae CRE infection at RCWMCH Ombeva Oliver Malande, Annerie du Plessis, Colleen Bamford, Brian Eley Presenter: Ombeva Malande Red Cross Children's
More informationAntibiotic Usage Guidelines in Hospital
SUPPLEMENT TO JAPI december VOL. 58 51 Antibiotic Usage Guidelines in Hospital Camilla Rodrigues * Use of surveillance data information of Hospital antibiotic policy guidelines from Hinduja Hospital. The
More informationMulti-Drug Resistant Organisms (MDRO)
Multi-Drug Resistant Organisms (MDRO) 2016 What are MDROs? Multi-drug resistant organisms, or MDROs, are bacteria resistant to current antibiotic therapy and therefore difficult to treat. MDROs can cause
More informationPreventing Multi-Drug Resistant Organism (MDRO) Infections. For National Patient Safety Goal
Preventing Multi-Drug Resistant Organism (MDRO) Infections For National Patient Safety Goal 07.03.01 2009 Methicillin Resistant Staphlococcus aureus (MRSA) About 3-8% of the population at large is a carrier
More informationAntimicrobial Susceptibility Profile of E. coli Isolates Causing Urosepsis: Single Centre Experience
International Journal of Current Microbiology and Applied Sciences ISSN: 2319-7706 Volume 7 Number 05 (2018) Journal homepage: http://www.ijcmas.com Original Research Article https://doi.org/10.20546/ijcmas.2018.705.298
More informationWitchcraft for Gram negatives
Witchcraft for Gram negatives Dr Subramanian S MD DNB MNAMS AB (Medicine, Infect Dis) Infectious Diseases Consultant Global Health City, Chennai www.asksubra.com Drug resistance follows the drug like a
More informationDr Vivien CHUANG Associate Consultant Infection Control Branch, Centre for Health Protection/ Infectious Disease Control and Training Center,
Dr Vivien CHUANG Associate Consultant Infection Control Branch, Centre for Health Protection/ Infectious Disease Control and Training Center, Hospital Authority NDM-1, which stands for New Delhi Metallo-beta-lactamase-1
More informationInt.J.Curr.Microbiol.App.Sci (2017) 6(3):
International Journal of Current Microbiology and Applied Sciences ISSN: 2319-7706 Volume 6 Number 3 (2017) pp. 891-895 Journal homepage: http://www.ijcmas.com Original Research Article https://doi.org/10.20546/ijcmas.2017.603.104
More informationMultidrug-Resistant Organisms: How Do We Define them? How do We Stop Them?
Multidrug-Resistant Organisms: How Do We Define them? How do We Stop Them? Roberta B. Carey, PhD Centers for Disease Control and Prevention Division of Healthcare Quality Promotion Why worry? MDROs Clinical
More information03/09/2014. Infection Prevention and Control A Foundation Course. Talk outline
Infection Prevention and Control A Foundation Course 2014 What is healthcare-associated infection (HCAI), antimicrobial resistance (AMR) and multi-drug resistant organisms (MDROs)? Why we should be worried?
More informationCONTAGIOUS COMMENTS Department of Epidemiology
VOLUME XXIII NUMBER 1 July 2008 CONTAGIOUS COMMENTS Department of Epidemiology Bugs and Drugs Elaine Dowell, SM (ASCP), Marti Roe SM (ASCP), Ann-Christine Nyquist MD, MSPH Are the bugs winning? The 2007
More informationMICRONAUT MICRONAUT-S Detection of Resistance Mechanisms. Innovation with Integrity BMD MIC
MICRONAUT Detection of Resistance Mechanisms Innovation with Integrity BMD MIC Automated and Customized Susceptibility Testing For detection of resistance mechanisms and specific resistances of clinical
More informationBacterial Pathogens in Urinary Tract Infection and Antibiotic Susceptibility Pattern from a Teaching Hospital, Bengaluru, India
ISSN: 2319-7706 Volume 4 Number 11 (2015) pp. 731-736 http://www.ijcmas.com Original Research Article Bacterial Pathogens in Urinary Tract Infection and Antibiotic Susceptibility Pattern from a Teaching
More informationFlorida Health Care Association District 2 January 13, 2015 A.C. Burke, MA, CIC
Florida Health Care Association District 2 January 13, 2015 A.C. Burke, MA, CIC 11/20/2014 1 To describe carbapenem-resistant Enterobacteriaceae. To identify laboratory detection standards for carbapenem-resistant
More informationAntimicrobial Cycling. Donald E Low University of Toronto
Antimicrobial Cycling Donald E Low University of Toronto Bad Bugs, No Drugs 1 The Antimicrobial Availability Task Force of the IDSA 1 identified as particularly problematic pathogens A. baumannii and
More informationDr Neeraj Goel Sr. Consultant Department of Clinical Microbiology. Sir Ganga Ram Hospital
Dr Neeraj Goel Sr. Consultant Department of Clinical Microbiology Sir Ganga Ram Hospital Resistance profile of MDROs in ICU: Quinolone: 80% Amikacin: 75% Cefaperazone sulbactum: 79% Carbapenems: 79% Super
More informationAerobic bacterial infections in a burns unit of Sassoon General Hospital, Pune
Original article Aerobic bacterial infections in a burns unit of Sassoon General Hospital, Pune Patil P, Joshi S, Bharadwaj R. Department of Microbiology, B.J. Medical College, Pune, India. Corresponding
More informationDr Kamini Walia Indian Council of Medical Research
Dr Kamini Walia Indian Council of Medical Research The apex body in India for the formulation, coordination and promotion of biomedical research under Department of Health Research, Ministry of Health
More information9.4 Antimicrobial Resistance
9.4 Antimicrobial Resistance a) Key Pathogens causing Bloodstream Infections 2016 Summary Estimated 99% coverage of the Irish population versus 97% in 2015 There were 3,057 reports of invasive E. coli
More informationPrevalence of Metallo-Beta-Lactamase Producing Pseudomonas aeruginosa and its antibiogram in a tertiary care centre
International Journal of Current Microbiology and Applied Sciences ISSN: 2319-7706 Volume 4 Number 9 (2015) pp. 952-956 http://www.ijcmas.com Original Research Article Prevalence of Metallo-Beta-Lactamase
More informationMicrobiology. Multi-Drug-Resistant bacteria / MDR: laboratory diagnostics and prevention. Antimicrobial resistance / MDR:
Microbiology Multi-Drug-Resistant bacteria / MDR: laboratory diagnostics and prevention June 2017 MeshHp (VS) Medical Care Center Dr. Eberhard & Partner Dortmund (ÜBAG) www.labmed.de MVZ Dr. Eberhard &
More informationPost-operative surgical wound infection
Med. J. Malaysia Vol. 45 No. 4 December 1990 Post-operative surgical wound infection Yasmin Abu Hanifah, MBBS, MSc. (London) Lecturer Department of Medical Microbiology, Faculty of Medicine, University
More informationMulti-Drug Resistant Gram Negative Organisms POLICY REVIEW DATE EXTENDED Printed copies must not be considered the definitive version
Multi-Drug Resistant Gram Negative Organisms POLICY REVIEW DATE EXTENDED 2018 Printed copies must not be considered the definitive version DOCUMENT CONTROL POLICY NO. IC-122 Policy Group Infection Control
More informationUnderstanding the Hospital Antibiogram
Understanding the Hospital Antibiogram Sharon Erdman, PharmD Clinical Professor Purdue University College of Pharmacy Infectious Diseases Clinical Pharmacist Eskenazi Health 5 Understanding the Hospital
More informationMicrobiology of War Wounds AUBMC Experience
Microbiology of War Wounds AUBMC Experience Abdul Rahman Bizri MD MSc Division of Infectious Diseases Department of Internal Medicine AUBMC Conflict Medicine Program - AUB Current Middle- East Geopolitical
More informationEducating Clinical and Public Health Laboratories About Antimicrobial Resistance Challenges
Educating Clinical and Public Health Laboratories About Antimicrobial Resistance Challenges Janet Hindler, MCLS MT(ASCP) UCLA Medical Center jhindler@ucla.edu also working as a consultant with the Association
More informationSurveillance of Antimicrobial Resistance among Bacterial Pathogens Isolated from Hospitalized Patients at Chiang Mai University Hospital,
Original Article Vol. 28 No. 1 Surveillance of Antimicrobial Resistance:- Chaiwarith R, et al. 3 Surveillance of Antimicrobial Resistance among Bacterial Pathogens Isolated from Hospitalized Patients at
More informationHospital Acquired Infections in the Era of Antimicrobial Resistance
Hospital Acquired Infections in the Era of Antimicrobial Resistance Datuk Dr Christopher KC Lee Infectious Diseases Unit Department of Medicine Sungai Buloh Hospital Patient Story 23 Year old female admitted
More informationINCIDENCE OF BACTERIAL COLONISATION IN HOSPITALISED PATIENTS WITH DRUG-RESISTANT TUBERCULOSIS
INCIDENCE OF BACTERIAL COLONISATION IN HOSPITALISED PATIENTS WITH DRUG-RESISTANT TUBERCULOSIS 1 Research Associate, Drug Utilisation Research Unit, Nelson Mandela University 2 Human Sciences Research Council,
More informationAntibiotic Resistance in India
Antibiotic Resistance in India Sumanth Gandra MD, MPH Center for Disease Dynamics, Economics & Policy July 5, 2017 AMR Cross Council Initiative Challenges and Opportunities Workshop, Heathrow Disclaimer/Disclosures
More informationWhy should we care about multi-resistant bacteria? Clinical impact and
Why should we care about multi-resistant bacteria? Clinical impact and public health implications Prof. Stephan Harbarth Infection Control Program Geneva, Switzerland and Ebola (in 2014/2015) Increased
More informationIntrinsic, implied and default resistance
Appendix A Intrinsic, implied and default resistance Magiorakos et al. [1] and CLSI [2] are our primary sources of information on intrinsic resistance. Sanford et al. [3] and Gilbert et al. [4] have been
More informationAntibiotic Stewardship Program (ASP) CHRISTUS SETX
Antibiotic Stewardship Program (ASP) CHRISTUS SETX Program Goals I. Judicious use of antibiotics Decrease use of broad spectrum antibiotics and deescalate use based on clinical symptoms Therapeutic duplication:
More informationEARS Net Report, Quarter
EARS Net Report, Quarter 4 213 March 214 Key Points for 213* Escherichia coli: The proportion of patients with invasive infections caused by E. coli producing extended spectrum β lactamases (ESBLs) increased
More informationAntimicrobial Susceptibility Patterns
Antimicrobial Susceptibility Patterns KNH SURGERY Department Masika M.M. Department of Medical Microbiology, UoN Medicines & Therapeutics Committee, KNH Outline Methodology Overall KNH data Surgery department
More informationInfection Control of Emerging Diseases
2016 EPS Training Event Martin E. Evans, MD Director, VHA MDRO Program National Infectious Diseases Service Lexington, KY & Cincinnati, OH Infection Control of Emerging Diseases 2016 EPS Training Event
More informationPrevention, Management, and Reporting of Carbapenem-Resistant Enterobacteriaceae
Prevention, Management, and Reporting of Carbapenem-Resistant Enterobacteriaceae Dawn Terashita MD, MPH Acute Communicable Disease Control Los Angeles County Department of Public Health September 28, 2017
More informationAntimicrobial Stewardship Strategy: Antibiograms
Antimicrobial Stewardship Strategy: Antibiograms A summary of the cumulative susceptibility of bacterial isolates to formulary antibiotics in a given institution or region. Its main functions are to guide
More informationSafe Patient Care Keeping our Residents Safe Use Standard Precautions for ALL Residents at ALL times
Safe Patient Care Keeping our Residents Safe 2016 Use Standard Precautions for ALL Residents at ALL times #safepatientcare Do bugs need drugs? Dr Deirdre O Brien Consultant Microbiologist Mercy University
More informationAntibiotic Stewardship in the Hospital Setting
Antibiotic Stewardship in the Hospital Setting G. Evans, MD FRCPC Medical Director, Infection Prevention & Control Kingston General Hospital & Hotel Dieu Hospital EOPIC September 26, 2012 Stewardship stew-ard-ship
More informationConcise Antibiogram Toolkit Background
Background This toolkit is designed to guide nursing homes in creating their own antibiograms, an important tool for guiding empiric antimicrobial therapy. Information about antibiograms and instructions
More informationNosocomial Infections: What Are the Unmet Needs
Nosocomial Infections: What Are the Unmet Needs Jean Chastre, MD Service de Réanimation Médicale Hôpital Pitié-Salpêtrière, AP-HP, Université Pierre et Marie Curie, Paris 6, France www.reamedpitie.com
More information2012 ANTIBIOGRAM. Central Zone Former DTHR Sites. Department of Pathology and Laboratory Medicine
2012 ANTIBIOGRAM Central Zone Former DTHR Sites Department of Pathology and Laboratory Medicine Medically Relevant Pathogens Based on Gram Morphology Gram-negative Bacilli Lactose Fermenters Non-lactose
More informationHospital ID: 831. Bourguiba Hospital. Tertiary hospital
Global Point Prevalence Survey of Antimicrobial Consumption and Resistance in hospitals worldwide Hospital ID: 831 Habib Bourguiba Hospital Tertiary hospital Tunisia Point Prevalence Survey Habib 2017
More informationTwo (II) Upon signature
Page 1/5 SCREENING FOR ANTIBIOTIC RESISTANT ORGANISMS (AROS) IN ACUTE CARE AND LONG TERM CARE Infection Prevention and Control IPC 050 Issuing Authority (sign & date) Office of Administrative Responsibility
More informationCONTAGIOUS COMMENTS Department of Epidemiology
VOLUME XXIX NUMBER 3 November 2014 CONTAGIOUS COMMENTS Department of Epidemiology Bugs and Drugs Elaine Dowell SM MLS (ASCP), Marti Roe SM MLS (ASCP), Sarah Parker MD, Jason Child PharmD, and Samuel R.
More informationInfection Prevention Highlights for the Medical Staff. Pamela Rohrbach MSN, RN, CIC Director of Infection Prevention
Highlights for the Medical Staff Pamela Rohrbach MSN, RN, CIC Director of Infection Prevention Standard Precautions every patient every time a. Hand Hygiene b. Use of Personal Protective Equipment (PPE)
More informationOther Enterobacteriaceae
GUIDE TO INFECTION CONTROL IN THE HOSPITAL CHAPTER NUMBER 50: Other Enterobacteriaceae Author Kalisvar Marimuthu, MD Chapter Editor Michelle Doll, MD, MPH Topic Outline Topic outline - Key Issues Known
More informationVaccination as a potential strategy to combat Antimicrobial Resistance in the elderly
Vaccination as a potential strategy to combat Antimicrobial Resistance in the elderly Wilbur Chen, MD, MS 22-23 March 2017 WHO meeting on Immunization of the Elderly The Problem Increasing consumption
More informationAntibiotic Resistance in the Post-Acute and Long-Term Care Settings: Strategies for Stewardship
Antibiotic Resistance in the Post-Acute and Long-Term Care Settings: Strategies for Stewardship J. Hudson Garrett Jr., PhD, MSN, MPH, FNP-BC, PLNC, CDONA, IP-BC, GDCN, CDP, CADDCT, CALN, VA-BC, AS-BC,
More informationLindsay E. Nicolle University of Manitoba Winnipeg, CANADA
Lindsay E. Nicolle University of Manitoba Winnipeg, CANADA Long Term Care Facilities: Spectrum low acuity assisted living mobile independent Not LTAC high acuity complete functional disability dialysis
More informationCONTAGIOUS COMMENTS Department of Epidemiology
VOLUME XXVII NUMBER 6 July 2012 CONTAGIOUS COMMENTS Department of Epidemiology Bugs and Drugs Elaine B. Dowell SM, MLS (ASCP); Sarah K. Parker, MD; James K. Todd, MD Each year the Children s Hospital Colorado
More informationThe Rise of Antibiotic Resistance: Is It Too Late?
The Rise of Antibiotic Resistance: Is It Too Late? Paul D. Holtom, MD Professor of Medicine and Orthopaedics USC Keck School of Medicine None DISCLOSURES THE PROBLEM Antibiotic resistance is one of the
More informationAntimicrobial Resistance Surveillance from sentinel public hospitals, South Africa, 2013
Antimicrobial Resistance Surveillance from sentinel public s, South Africa, 213 Authors: Olga Perovic 1,2, Melony Fortuin-de Smidt 1, and Verushka Chetty 1 1 National Institute for Communicable Diseases
More informationInfection control and antimicrobial resistance in Republic of Moldova. Riga, May 6-8, 2015
Infection control and antimicrobial resistance in Republic of Moldova Riga, May 6-8, 2015 Republic of Moldova Population: 3.9 million Area: 33.7 sq. km Life expectancy: men 65.5 years women 73.3 years
More informationRCH antibiotic susceptibility data
RCH antibiotic susceptibility data The following represent RCH antibiotic susceptibility data from 2008. This data is used to inform antibiotic guidelines used at RCH. The data includes all microbiological
More informationAntimicrobial Stewardship: efective implementation for improved clinical outcomes
The Challenge of MDR and XDR infections; Barcelona September 2018 Antimicrobial Stewardship: efective implementation for improved clinical outcomes José Miguel Cisneros Herreros Infectious Diseases Department
More informationInternationally indexed journal
www.ijpbs.net Internationally indexed journal Indexed in Chemical Abstract Services (USA), Index coppernicus, Ulrichs Directory of Periodicals, Google scholar, CABI,DOAJ, PSOAR, EBSCO, Open J gate, Proquest,
More informationAntimicrobial Stewardship/Statewide Antibiogram. Felicia Matthews Senior Consultant, Pharmacy Specialty BD MedMined Services
Antimicrobial Stewardship/Statewide Antibiogram Felicia Matthews Senior Consultant, Pharmacy Specialty BD MedMined Services Disclosures Employee of BD Corporation MedMined Services Agenda CMS and JCAHO
More informationAberdeen Hospital. Antibiotic Susceptibility Patterns For Commonly Isolated Organisms For 2015
Aberdeen Hospital Antibiotic Susceptibility Patterns For Commonly Isolated s For 2015 Services Laboratory Microbiology Department Aberdeen Hospital Nova Scotia Health Authority 835 East River Road New
More informationCarbapenemase-producing Enterobacteriaceae (CRE) T H E L A T E S T I N T H E G R O W I N G L I S T O F S U P E R B U G S
Carbapenemase-producing Enterobacteriaceae (CRE) T H E L A T E S T I N T H E G R O W I N G L I S T O F S U P E R B U G S CRE Enterobacteriaceae (Gram Negative Bacilli) Citrobacter species Escherichia coli***
More informationA retrospective analysis of urine culture results issued by the microbiology department, Teaching Hospital, Karapitiya
A retrospective analysis of urine culture results issued by the microbiology department, Teaching Hospital, Karapitiya LU Edirisinghe 1, D Vidanagama 2 1 Senior Registrar in Medicine, 2 Consultant Microbiologist,
More informationTherapeutic Strategies for Gram Negative Multi- Clinical Associate Professor Infectious Diseases Specialist The Ohio State University Medical Center
Therapeutic Strategies for Gram Negative Multi- Bacterial Infections Debra A. Goff, Pharm.D., FCCP Clinical Associate Professor Infectious Diseases Specialist The Ohio State University Medical Center Columbus,
More informationCarbapenemase-Producing Enterobacteriaceae (CPE)
Carbapenemase-Producing Enterobacteriaceae (CPE) September 21, 2017 Maryam Khan Peel Public Health Madeleine Ashcroft Public Health Ontario Objectives Differentiate the acronyms related to CPE (CPE,CPO,CRE,CRO)
More informationNew Drugs for Bad Bugs- Statewide Antibiogram
New Drugs for Bad Bugs- Statewide Antibiogram Felicia Matthews, Pharm.D., BCPS Senior Consultant, Pharmacy Specialty BE MedMined Services Disclosures Employee of BD Corporation MedMined Services Agenda
More informationAntibiotic Resistance. Antibiotic Resistance: A Growing Concern. Antibiotic resistance is not new 3/21/2011
Antibiotic Resistance Antibiotic Resistance: A Growing Concern Judy Ptak RN MSN Infection Prevention Practitioner Dartmouth-Hitchcock Medical Center Lebanon, NH Occurs when a microorganism fails to respond
More informationESBL- and carbapenemase-producing microorganisms; state of the art. Laurent POIREL
ESBL- and carbapenemase-producing microorganisms; state of the art Laurent POIREL Medical and Molecular Microbiology Unit Dept of Medicine University of Fribourg Switzerland INSERM U914 «Emerging Resistance
More informationRecommendations for Implementation of Antimicrobial Stewardship Restrictive Interventions in Acute Hospitals in Ireland
Recommendations for Implementation of Antimicrobial Stewardship Restrictive Interventions in Acute Hospitals in Ireland A report by the Hospital Antimicrobial Stewardship Working Group, a subgroup of the
More informationDr. Shaiful Azam Sazzad. MD Student (Thesis Part) Critical Care Medicine Dhaka Medical College
Dr. Shaiful Azam Sazzad MD Student (Thesis Part) Critical Care Medicine Dhaka Medical College INTRODUCTION ICU acquired infection account for substantial morbidity, mortality and expense. Infection and
More informationReducing the Burden of Severe Sepsis and Infections in Indian ICUs
Reducing the Burden of Severe Sepsis and Infections in Indian ICUs J.V. Divatia Professor & Head Department of Anaesthesia, Critical Care & Pain Tata Memorial Hospital Mumbai India Infections in the ICU
More information9.5 Antimicrobial Resistance
9.5 Antimicrobial Resistance Key Points In 215, there was a slight reduction in coverage of the Irish population by EARS-Net versus 214, from 1% to 97% There were 2,697 reports of invasive Escherichia
More informationGram negative bacteraemia
Gram negative bacteraemia David Enoch Consultant Medical Microbiologist PHE Cambridge Cambridge University Hospitals NHS FT Overview Gram negative bacteraemia Changing epidemiology in England Epidemiology
More informationMulti-drug resistant microorganisms
Multi-drug resistant microorganisms Arzu TOPELI Director of MICU Hacettepe University Faculty of Medicine, Ankara-Turkey Council Member of WFSICCM Deaths in the US declined by 220 per 100,000 with the
More information2016/LSIF/FOR/007 Improving Antimicrobial Use and Awareness in Korea
2016/LSIF/FOR/007 Improving Antimicrobial Use and Awareness in Korea Submitted by: Asia Pacific Foundation for Infectious Diseases Policy Forum on Strengthening Surveillance and Laboratory Capacity to
More informationOverview of Needs on the Ground and Surveillance Issues The Case of India
Overview of Needs on the Ground and Surveillance Issues The Case of India Dr Kamini Walia, Division of Epidemiology and Communicable Diseases Indian Council of Medical Research Indian Council of Medical
More informationMechanism of antibiotic resistance
Mechanism of antibiotic resistance Dr.Siriwoot Sookkhee Ph.D (Biopharmaceutics) Department of Microbiology Faculty of Medicine, Chiang Mai University Antibiotic resistance Cross-resistance : resistance
More informationAdvances in Antimicrobial Stewardship (AMS) at University Hospital Southampton
Advances in Antimicrobial Stewardship (AMS) at University Hospital Southampton Dr Julian Sutton Consultant in Infectious Diseases & Medical Microbiology Federation of Infection Societies 1 st December,
More informationPreserving bacterial susceptibility Implementing Antimicrobial Stewardship Programs Debra A. Goff, Pharm.D., FCCP
Preserving bacterial susceptibility Implementing Antimicrobial Stewardship Programs Debra A. Goff, Pharm.D., FCCP Clinical Associate Professor Infectious Diseases Specialist The Ohio State University Medical
More informationThe International Collaborative Conference in Clinical Microbiology & Infectious Diseases
The International Collaborative Conference in Clinical Microbiology & Infectious Diseases PLUS: Antimicrobial stewardship in hospitals: Improving outcomes through better education and implementation of
More informationOAHHS Webinar. Christopher D. Pfeiffer, MD, MHS April 30, 2014
OAHHS Webinar Christopher D. Pfeiffer, MD, MHS April 30, 2014 Learning Objectives / Outline 1. Understand: What are CRE? Which CRE are most important? Why? 2. Learn about CRE epidemiology, nationally and
More informationANTIMICROBIAL RESISTANCE SURVEILLANCE FROM SENTINEL PUBLIC HOSPITALS, SOUTH AFRICA, 2014
ANTIMICROBIAL RESISTANCE SURVEILLANCE FROM SENTINEL PUBLIC HOSPITALS, SOUTH AFRICA, 2014 Olga Perovic, 1,2 Verushka Chetty 1 & Samantha Iyaloo 1 1 National Institute for Communicable Diseases, NHLS 2 Department
More informationCollecting and Interpreting Stewardship Data: Breakout Session
Collecting and Interpreting Stewardship Data: Breakout Session Michael S. Calderwood, MD, MPH Regional Hospital Epidemiologist, Dartmouth-Hitchcock Medical Center March 20, 2019 None Disclosures Outline
More informationDetection of ESBL Producing Gram Negative Uropathogens and their Antibiotic Resistance Pattern from a Tertiary Care Centre, Bengaluru, India
ISSN: 2319-7706 Volume 4 Number 12 (2015) pp. 578-583 http://www.ijcmas.com Original Research Article Detection of ESBL Producing Gram Negative Uropathogens and their Antibiotic Resistance Pattern from
More informationNew Opportunities for Microbiology Labs to Add Value to Antimicrobial Stewardship Programs
New Opportunities for Microbiology Labs to Add Value to Antimicrobial Stewardship Programs Patrick R. Murray, PhD Senior Director, WW Scientific Affairs 2017 BD. BD, the BD Logo and all other trademarks
More informationAntibiogram of Bacterial Isolates at Hail General Hospital, KSA June 1 December 31, 2012
IOSR Journal of Nursing and Health Science (IOSR-JNHS) e-issn: 2320 1959.p- ISSN: 2320 1940 Volume 4, Issue 1 Ver. I (Jan.-Feb. 2015), PP 21-26 www.iosrjournals.org Antibiogram of Bacterial Isolates at
More informationAntimicrobial Susceptibility Testing: Advanced Course
Antimicrobial Susceptibility Testing: Advanced Course Cascade Reporting Cascade Reporting I. Selecting Antimicrobial Agents for Testing and Reporting Selection of the most appropriate antimicrobials to
More informationSuggestions for appropriate agents to include in routine antimicrobial susceptibility testing
Suggestions for appropriate agents to include in routine antimicrobial susceptibility testing These suggestions are intended to indicate minimum sets of agents to test routinely in a diagnostic laboratory
More informationBirgit Ross Hospital Hygiene University Hospital Essen Essen, Germany. Should we screen for multiresistant gramnegative Bacteria?
Birgit Ross Hospital Hygiene University Hospital Essen Essen, Germany Should we screen for multiresistant gramnegative Bacteria? CONCLUSIONS: A program of universal surveillance, contact precautions,
More informationAvailable online at ISSN No:
Available online at www.ijmrhs.com ISSN No: 2319-5886 International Journal of Medical Research & Health Sciences, 2017, 6(4): 36-42 Comparative Evaluation of In-Vitro Doripenem Susceptibility with Other
More informationFighting MDR Pathogens in the ICU
Fighting MDR Pathogens in the ICU Dr. Murat Akova Hacettepe University School of Medicine, Department of Infectious Diseases, Ankara, Turkey 1 50.000 deaths each year in US and Europe due to antimicrobial
More information2017 Antibiogram. Central Zone. Alberta Health Services. including. Red Deer Regional Hospital. St. Mary s Hospital, Camrose
2017 Antibiogram Central Zone Alberta Health Services including Red Deer Regional Hospital St. Mary s Hospital, Camrose Introduction This antibiogram is a cumulative report of the antimicrobial susceptibility
More information11/22/2016. Hospital-acquired Infections Update Disclosures. Outline. No conflicts of interest to disclose. Hot topics:
Hospital-acquired Infections Update 2016 APIC-CI Conference November 17 th, 2016 Jay R. McDonald, MD Chief, ID Section VA St. Louis Health Care System Assistant Professor of medicine Washington University
More informationDR. MICHAEL A. BORG DIRECTOR OF INFECTION PREVENTION & CONTROL MATER DEI HOSPITAL - MALTA
DR. MICHAEL A. BORG DIRECTOR OF INFECTION PREVENTION & CONTROL MATER DEI HOSPITAL - MALTA The good old days The dread (of) infections that used to rage through the whole communities is muted Their retreat
More informationOutline. Antimicrobial resistance. Antimicrobial resistance in gram negative bacilli. % susceptibility 7/11/2010
Multi-Drug Resistant Organisms Is Combination Therapy the Way to Go? Sutthiporn Pattharachayakul, PharmD Prince of Songkhla University, Thailand Outline Prevalence of anti-microbial resistance in Acinetobacter
More informationBACTERIOLOGICAL PROFILE AND ANTIMICROBIAL SUSCEPTIBILITY PATTERN OF ISOLATES OF NEONATAL SEPTICEMIA IN A TERTIARY CARE HOSPITAL
IJCRR Section: Healthcare Sci. Journal Impact Factor 4.016 Research Article BACTERIOLOGICAL PROFILE AND ANTIMICROBIAL SUSCEPTIBILITY PATTERN OF ISOLATES OF NEONATAL SEPTICEMIA IN A TERTIARY CARE HOSPITAL
More informationNorth West Neonatal Operational Delivery Network Working together to provide the highest standard of care for babies and families
Document Title and Reference : Guideline for the management of multi-drug resistant organisms (MDRO) Main Author (s) Simon Power Ratified by: GM NSG Date Ratified: February 2012 Review Date: March 2017
More information5/4/2018. Multidrug Resistant Organisms (MDROs) Objectives. Outline. Define a multi-drug resistant organism (MDRO)
Multidrug Resistant Organisms (MDROs) Kasturi Shrestha, M.D. 05/11/2018 Objectives Define a multi-drug resistant organism (MDRO) Identify most challenging MDROs in healthcare Identify reasons for health
More informationAcinetobacter species-associated infections and their antibiotic susceptibility profiles in Malaysia.
Biomedical Research 12; 23 (4): 571-575 ISSN 97-938X Scientific Publishers of India Acinetobacter species-associated infections and their antibiotic susceptibility profiles in Malaysia. Nazmul MHM, Jamal
More informationAerobic Bacterial Profile and Antimicrobial Susceptibility Pattern of Pus Isolates in a Tertiary Care Hospital in Hadoti Region
International Journal of Current Microbiology and Applied Sciences ISSN: 2319-7706 Volume 6 Number 5 (2017) pp. 2866-2873 Journal homepage: http://www.ijcmas.com Original Research Article https://doi.org/10.20546/ijcmas.2017.605.326
More information